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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:208.2 nTPM
HPA Brain:234.4 nTPM
GTEx:208.2 nTPM
FANTOM5:520.3 Scaled Tags Per Million
Pig:156.0 nTPM
Mouse:582.8 nTPM
Allen mouse:14.7 Expression energy

MIDBRAIN - Annotated protein expression
Pending normal tissue analysis

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

234.4
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 191.3
1833 Male, age 53, unknown 256.5
2411 Female, age 72, unknown 254.3
1830 Male, age 51, unknown 252.2
1870 Female, age 42, unknown 221.9
2828 Female, age 72, unknown 193.8
2019 Male, age 18, unknown 186.5
2586 Male, age 75, left hemisphere 153.1
1827 Male, age 72, unknown 139.9
2666 Male, age 74, left hemisphere 132.7
2219 Male, age 76, both hemispheres 122.5
Dorsal raphe nucleus
nTPM: 136.8
2750 Male, age 76, both hemispheres 220.6
2016 Female, age 72, unknown 155.3
1828 Male, age 53, unknown 128.8
2298 Female, age 72, unknown 99.8
2047 Male, age 72, unknown 79.4
Inferior colliculus
nTPM: 120.2
2849 Male, age 72, unknown 138.6
1848 Female, age 42, unknown 133.0
1890 Male, age 53, unknown 109.9
2097 Female, age 72, unknown 99.3
Median raphe nucleus
nTPM: 97.4
2220 Male, age 76, midline 97.4
Periaquaductal grey, anterior
nTPM: 108.1
2502 Female, age 75, unknown 124.8
1947 Male, age 18, unknown 112.3
1795 Male, age 51, unknown 87.3
Periaquaductal grey, dorsal
nTPM: 100.0
2464 Female, age 72, unknown 155.9
1831 Male, age 72, unknown 101.0
2850 Male, age 76, both hemispheres 73.2
1840 Male, age 53, unknown 70.0
Periaquaductal grey, lateral
nTPM: 106.4
2053 Male, age 18, unknown 126.9
2272 Male, age 74, both hemispheres 116.6
2140 Male, age 76, both hemispheres 75.8
Pretectal area
nTPM: 131.9
2316 Male, age 76, right hemisphere 193.8
1815 Male, age 53, unknown 187.9
2667 Female, age 75, unknown 160.1
1817 Female, age 42, unknown 148.2
2407 Male, age 75, both hemispheres 147.0
2825 Male, age 18, unknown 134.8
2007 Male, age 72, unknown 115.2
2273 Male, age 74, both hemispheres 115.2
2224 Female, age 72, unknown 105.4
1816 Male, age 51, unknown 72.0
1944 Female, age 72, unknown 71.8
Red nucleus
nTPM: 234.4
1904 Male, age 53, unknown 319.1
1821 Female, age 72, unknown 287.7
1865 Male, age 51, unknown 274.8
2823 Male, age 76, right hemisphere 264.1
2769 Male, age 72, unknown 255.7
2227 Male, age 72, unknown 254.5
2785 Male, age 18, unknown 240.9
1954 Female, age 42, unknown 232.3
2503 Female, age 72, unknown 220.7
2588 Male, age 74, left hemisphere 204.9
2725 Female, age 75, unknown 131.1
2584 Male, age 75, left hemisphere 127.4
Substantia nigra
nTPM: 138.1
1851 Male, age 51, unknown 173.7
2583 Male, age 75, right hemisphere 170.6
2699 Male, age 18, unknown 163.6
2409 Female, age 72, unknown 162.6
2590 Female, age 75, unknown 147.0
1889 Female, age 72, unknown 139.1
2665 Male, age 74, both hemispheres 116.0
2241 Male, age 72, unknown 111.1
1916 Female, age 42, unknown 103.8
1941 Male, age 53, unknown 94.0
Superior colliculus
nTPM: 169.2
1995 Male, age 72, unknown 283.9
1913 Female, age 42, unknown 247.7
1895 Male, age 76, right hemisphere 212.7
1839 Male, age 51, unknown 184.9
2668 Female, age 75, unknown 168.7
2587 Male, age 74, left hemisphere 160.3
1796 Male, age 53, unknown 148.5
2664 Male, age 75, both hemispheres 110.5
2261 Male, age 18, unknown 88.1
2087 Female, age 72, unknown 86.5
Ventral tegmental area
nTPM: 158.6
2223 Female, age 72, unknown 231.8
2410 Female, age 72, unknown 208.5
1915 Female, age 42, unknown 141.1
1942 Male, age 51, unknown 130.3
2218 Male, age 76, both hemispheres 123.7
2021 Male, age 53, unknown 116.2

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

208.2
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 208.2
Samples: 139

Max nTPM: 714.9
Min nTPM: 70.9
Std nTPM: 118.0
Median nTPM: 177.1
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 714.9
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 696.6
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 579.4
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 575.7
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 560.9
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 497.6
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 434.8
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 418.9
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 396.8
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 391.6
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 389.3
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 389.2
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 384.2
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 375.4
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 372.3
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 360.5
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 345.0
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 332.4
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 323.8
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 317.6
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 304.1
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 293.4
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 290.2
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 281.2
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 280.3
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 276.7
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 269.8
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 264.7
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 263.9
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 261.9
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 259.7
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 259.2
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 258.6
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 258.0
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 249.6
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 239.1
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 237.7
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 234.4
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 233.8
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 233.8
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 230.1
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 219.0
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 218.2
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 217.7
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 214.9
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 214.9
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 213.7
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 209.1
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 208.7
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 207.1
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 201.1
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 200.2
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 198.0
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 197.5
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 196.9
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 196.4
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 194.6
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 194.3
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 192.9
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 190.8
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 190.5
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 188.4
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 187.8
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 185.1
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 183.9
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 183.9
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 181.3
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 181.2
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 179.3
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 177.1
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 173.3
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 170.8
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 169.8
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 169.2
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 167.8
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 167.5
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 167.3
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 166.3
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 162.5
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 161.7
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 161.4
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 160.8
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 159.9
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 157.3
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 156.9
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 155.6
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 148.4
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 144.3
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 143.9
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 142.0
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 141.9
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 141.5
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 140.4
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 139.8
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 139.2
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 138.6
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 138.3
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 137.2
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 136.5
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 136.0
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 135.6
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 135.6
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 133.9
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 133.0
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 132.3
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 131.4
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 129.8
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 128.2
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 126.8
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 125.4
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 124.9
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 124.1
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 123.7
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 121.1
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 120.2
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 119.5
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 115.9
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 112.0
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 111.3
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 110.8
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 110.4
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 110.1
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 109.8
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 109.5
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 105.9
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 105.2
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 101.6
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 98.5
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 98.4
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 95.6
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 91.7
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 90.6
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 87.1
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 86.2
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 84.3
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 84.0
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 72.8
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 71.2
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 70.9
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

520.3
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 520.3
FF:10158-103A5 76 years, female 520.3

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

156.0
Pig sample Sample description nTPM
Substantia nigra
nTPM: 139.7
Samples: 4

Max nTPM: 240.7
Min nTPM: 93.7
Sample A Female 123.6
Sample B Female 93.7
Sample C Male 100.9
Sample D Male 240.7
Midbrain
nTPM: 156.0
Samples: 4

Max nTPM: 401.0
Min nTPM: 51.5
Sample A Female 401.0
Sample B Female 115.0
Sample C Male 51.5
Sample D Male 56.5
Periaqueductal gray
nTPM: 71.5
Samples: 3

Max nTPM: 91.4
Min nTPM: 47.0
Sample B Female 76.2
Sample C Male 47.0
Sample D Male 91.4
Superior colliculi
nTPM: 96.6
Samples: 4

Max nTPM: 133.7
Min nTPM: 49.8
Sample A Female 97.9
Sample B Female 49.8
Sample C Male 105.1
Sample D Male 133.7

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

582.8
Mouse sample Sample description nTPM
Midbrain
nTPM: 582.9
Samples: 4

Max nTPM: 689.3
Min nTPM: 499.6
Sample A Male 503.6
Sample B Male 499.6
Sample C Female 689.3
Sample D Female 638.9

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

14.7
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 14.7
386243 Antisense, RP_040804_01_D04, Mouse strain C57BL/6J (56 days, male) 14.7

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