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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
PRIMARY MOUSE DATA
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Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:65.5 nTPM
HPA Brain:82.9 nTPM
GTEx:65.5 nTPM
FANTOM5:1.7 Scaled Tags Per Million
Pig:219.9 nTPM
Mouse:216.1 nTPM
Allen mouse:10.7 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

82.9
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 50.8
1827 Male, age 72, unknown 95.6
1870 Female, age 42, unknown 66.7
2586 Male, age 75, left hemisphere 65.7
2828 Female, age 72, unknown 64.1
2411 Female, age 72, unknown 62.9
2219 Male, age 76, both hemispheres 41.0
2666 Male, age 74, left hemisphere 38.8
1830 Male, age 51, unknown 33.7
1833 Male, age 53, unknown 29.9
2019 Male, age 18, unknown 10.0
Dorsal raphe nucleus
nTPM: 36.1
2298 Female, age 72, unknown 57.0
2750 Male, age 76, both hemispheres 41.5
2016 Female, age 72, unknown 38.1
2047 Male, age 72, unknown 27.1
1828 Male, age 53, unknown 16.9
Inferior colliculus
nTPM: 39.7
2849 Male, age 72, unknown 53.6
1848 Female, age 42, unknown 43.8
2097 Female, age 72, unknown 35.0
1890 Male, age 53, unknown 26.4
Median raphe nucleus
nTPM: 49.6
2220 Male, age 76, midline 49.6
Periaquaductal grey, anterior
nTPM: 68.4
1795 Male, age 51, unknown 106.4
2502 Female, age 75, unknown 71.3
1947 Male, age 18, unknown 27.4
Periaquaductal grey, dorsal
nTPM: 61.4
2850 Male, age 76, both hemispheres 73.8
1831 Male, age 72, unknown 67.1
1840 Male, age 53, unknown 62.7
2464 Female, age 72, unknown 42.2
Periaquaductal grey, lateral
nTPM: 82.9
2053 Male, age 18, unknown 153.5
2140 Male, age 76, both hemispheres 60.7
2272 Male, age 74, both hemispheres 34.3
Pretectal area
nTPM: 58.3
2224 Female, age 72, unknown 185.7
2825 Male, age 18, unknown 145.0
2667 Female, age 75, unknown 57.3
2316 Male, age 76, right hemisphere 53.9
2407 Male, age 75, both hemispheres 37.1
1816 Male, age 51, unknown 35.1
2007 Male, age 72, unknown 30.7
2273 Male, age 74, both hemispheres 27.1
1815 Male, age 53, unknown 27.0
1944 Female, age 72, unknown 25.8
1817 Female, age 42, unknown 16.6
Red nucleus
nTPM: 15.2
2584 Male, age 75, left hemisphere 53.9
2227 Male, age 72, unknown 17.7
2769 Male, age 72, unknown 17.1
1821 Female, age 72, unknown 16.7
2725 Female, age 75, unknown 13.3
2823 Male, age 76, right hemisphere 12.3
1865 Male, age 51, unknown 10.4
1954 Female, age 42, unknown 10.0
1904 Male, age 53, unknown 8.4
2503 Female, age 72, unknown 8.4
2588 Male, age 74, left hemisphere 7.6
2785 Male, age 18, unknown 6.2
Substantia nigra
nTPM: 22.6
1941 Male, age 53, unknown 68.4
1889 Female, age 72, unknown 43.4
2241 Male, age 72, unknown 33.9
2590 Female, age 75, unknown 17.1
2699 Male, age 18, unknown 12.0
1916 Female, age 42, unknown 11.4
1851 Male, age 51, unknown 11.3
2583 Male, age 75, right hemisphere 11.2
2665 Male, age 74, both hemispheres 10.3
2409 Female, age 72, unknown 6.7
Superior colliculus
nTPM: 39.0
2261 Male, age 18, unknown 97.5
1839 Male, age 51, unknown 51.1
1895 Male, age 76, right hemisphere 49.2
1796 Male, age 53, unknown 48.5
2664 Male, age 75, both hemispheres 45.4
2587 Male, age 74, left hemisphere 40.6
1913 Female, age 42, unknown 22.2
2668 Female, age 75, unknown 18.0
2087 Female, age 72, unknown 14.3
1995 Male, age 72, unknown 3.7
Ventral tegmental area
nTPM: 37.7
1915 Female, age 42, unknown 60.3
2021 Male, age 53, unknown 52.8
1942 Male, age 51, unknown 33.9
2218 Male, age 76, both hemispheres 32.6
2223 Female, age 72, unknown 24.4
2410 Female, age 72, unknown 22.1

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

65.5
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 65.5
Samples: 139

Max nTPM: 941.8
Min nTPM: 0.9
Std nTPM: 113.9
Median nTPM: 34.1
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 941.8
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 560.5
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 480.6
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 404.3
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 310.9
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 276.9
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 246.1
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 236.8
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 222.4
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 189.6
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 186.9
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 186.6
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 182.7
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 156.7
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 153.1
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 136.0
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 131.8
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 120.7
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 120.0
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 118.4
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 117.9
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 113.0
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 105.7
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 100.5
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 92.9
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 87.6
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 85.0
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 83.5
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 76.3
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 75.4
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 69.1
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 63.3
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 61.4
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 61.0
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 61.0
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 57.0
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 55.9
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 55.3
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 55.1
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 54.5
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 52.1
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 51.0
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 50.2
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 48.4
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 48.2
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 46.9
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 46.3
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 45.6
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 45.5
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 45.1
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 44.5
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 44.4
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 44.4
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 44.1
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 42.7
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 42.6
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 42.5
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 41.8
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 41.0
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 40.4
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 39.4
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 38.6
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 38.5
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 38.5
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 38.2
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 37.9
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 37.7
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 36.3
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 35.8
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 34.1
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 33.6
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 33.0
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 31.7
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 31.5
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 30.7
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 30.7
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 30.6
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 30.0
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 29.9
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 27.6
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 26.8
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 26.4
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 25.8
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 21.5
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 20.9
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 20.7
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 20.3
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 19.6
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 18.6
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 18.4
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 17.9
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 17.3
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 17.1
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 16.9
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 16.8
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 13.4
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 12.9
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 12.7
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 12.6
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 12.5
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 11.5
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 11.3
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 11.2
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 10.7
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 10.7
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 10.4
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 10.1
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 9.6
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 9.5
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 9.4
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 9.4
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 9.2
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 8.7
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 8.5
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 8.3
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 7.9
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 7.2
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 5.9
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 5.8
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 5.6
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 5.5
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 5.4
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 5.3
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 5.0
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 4.8
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 4.6
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 4.4
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 4.1
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 4.1
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 4.0
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 3.2
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 2.7
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 2.5
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 2.0
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 1.9
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 1.6
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 1.3
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 1.1
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 0.9
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MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

1.7
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 1.7
FF:10158-103A5 76 years, female 1.7

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

219.9
Pig sample Sample description nTPM
Substantia nigra
nTPM: 126.7
Samples: 4

Max nTPM: 223.4
Min nTPM: 14.3
Sample A Female 223.4
Sample B Female 57.2
Sample C Male 211.9
Sample D Male 14.3
Midbrain
nTPM: 219.9
Samples: 4

Max nTPM: 417.2
Min nTPM: 29.1
Sample A Female 29.1
Sample B Female 128.2
Sample C Male 417.2
Sample D Male 305.1
Periaqueductal gray
nTPM: 111.2
Samples: 3

Max nTPM: 155.8
Min nTPM: 72.5
Sample B Female 72.5
Sample C Male 155.8
Sample D Male 105.4
Superior colliculi
nTPM: 175.8
Samples: 4

Max nTPM: 272.9
Min nTPM: 111.1
Sample A Female 201.5
Sample B Female 117.5
Sample C Male 272.9
Sample D Male 111.1

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

216.1
Mouse sample Sample description nTPM
Midbrain
nTPM: 216.1
Samples: 4

Max nTPM: 222.2
Min nTPM: 208.7
Sample A Male 221.2
Sample B Male 208.7
Sample C Female 212.4
Sample D Female 222.2

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

10.7
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 10.7
75496134 Antisense, RP_060523_03_F02, Mouse strain C57BL/6J (56 days, male) 12.2
75496136 Antisense, RP_060523_03_H02, Mouse strain C57BL/6J (56 days, male) 12.0
75492322 Antisense, RP_060523_03_F02, Mouse strain C57BL/6J (56 days, male) 11.8
75457438 Antisense, RP_060523_03_E02, Mouse strain C57BL/6J (56 days, male) 11.5
75496133 Antisense, RP_060523_03_E02, Mouse strain C57BL/6J (56 days, male) 11.5
75496135 Antisense, RP_060523_03_G02, Mouse strain C57BL/6J (56 days, male) 11.5
75492430 Antisense, RP_060523_03_H02, Mouse strain C57BL/6J (56 days, male) 11.2
75457440 Antisense, RP_060523_03_G02, Mouse strain C57BL/6J (56 days, male) 10.8
75492224 Antisense, RP_060523_03_E02, Mouse strain C57BL/6J (56 days, male) 10.5
75492428 Antisense, RP_060523_03_G02, Mouse strain C57BL/6J (56 days, male) 9.9
69117422 Antisense, RP_050330_01_B06, Mouse strain C57BL/6J (56 days, male) 9.8
75457439 Antisense, RP_060523_03_F02, Mouse strain C57BL/6J (56 days, male) 9.8
75496380 Antisense, RP_060523_03_F02, Mouse strain C57BL/6J (56 days, male) 9.5
75496390 Antisense, RP_060523_03_G02, Mouse strain C57BL/6J (56 days, male) 9.5
75496400 Antisense, RP_060523_03_H02, Mouse strain C57BL/6J (56 days, male) 9.5
75496370 Antisense, RP_060523_03_E02, Mouse strain C57BL/6J (56 days, male) 9.1
79556662 Antisense, RP_071204_01_B06, Mouse strain C57BL/6J (56 days, male) 7.4

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