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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:141.2 nTPM
HPA Brain:157.7 nTPM
GTEx:141.2 nTPM
FANTOM5:58.0 Scaled Tags Per Million
Pig:118.3 nTPM
Mouse:232.9 nTPM
Allen mouse:9.1 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

157.7
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 127.7
2586 Male, age 75, left hemisphere 208.2
2828 Female, age 72, unknown 151.2
1827 Male, age 72, unknown 141.7
2666 Male, age 74, left hemisphere 129.5
2019 Male, age 18, unknown 121.5
2411 Female, age 72, unknown 118.3
1870 Female, age 42, unknown 111.4
1833 Male, age 53, unknown 103.6
1830 Male, age 51, unknown 99.5
2219 Male, age 76, both hemispheres 91.6
Dorsal raphe nucleus
nTPM: 147.7
2298 Female, age 72, unknown 179.8
2047 Male, age 72, unknown 165.7
2016 Female, age 72, unknown 141.9
1828 Male, age 53, unknown 131.6
2750 Male, age 76, both hemispheres 119.5
Inferior colliculus
nTPM: 111.3
2097 Female, age 72, unknown 119.7
1848 Female, age 42, unknown 112.4
1890 Male, age 53, unknown 111.9
2849 Male, age 72, unknown 101.1
Median raphe nucleus
nTPM: 125.6
2220 Male, age 76, midline 125.6
Periaquaductal grey, anterior
nTPM: 157.7
1795 Male, age 51, unknown 175.9
2502 Female, age 75, unknown 149.9
1947 Male, age 18, unknown 147.2
Periaquaductal grey, dorsal
nTPM: 141.4
1840 Male, age 53, unknown 162.5
2850 Male, age 76, both hemispheres 149.6
1831 Male, age 72, unknown 139.1
2464 Female, age 72, unknown 114.2
Periaquaductal grey, lateral
nTPM: 147.2
2272 Male, age 74, both hemispheres 151.5
2140 Male, age 76, both hemispheres 150.5
2053 Male, age 18, unknown 139.6
Pretectal area
nTPM: 147.7
1816 Male, age 51, unknown 169.2
2007 Male, age 72, unknown 162.4
1944 Female, age 72, unknown 162.1
2273 Male, age 74, both hemispheres 155.7
1817 Female, age 42, unknown 148.5
1815 Male, age 53, unknown 146.7
2667 Female, age 75, unknown 141.8
2224 Female, age 72, unknown 141.5
2825 Male, age 18, unknown 136.5
2316 Male, age 76, right hemisphere 130.7
2407 Male, age 75, both hemispheres 129.6
Red nucleus
nTPM: 112.5
2785 Male, age 18, unknown 133.5
2584 Male, age 75, left hemisphere 124.4
2725 Female, age 75, unknown 116.7
1821 Female, age 72, unknown 115.5
2769 Male, age 72, unknown 112.6
1904 Male, age 53, unknown 110.4
2588 Male, age 74, left hemisphere 110.0
2503 Female, age 72, unknown 109.8
2823 Male, age 76, right hemisphere 109.0
2227 Male, age 72, unknown 103.1
1865 Male, age 51, unknown 102.9
1954 Female, age 42, unknown 101.9
Substantia nigra
nTPM: 142.9
1916 Female, age 42, unknown 181.0
1851 Male, age 51, unknown 159.5
2665 Male, age 74, both hemispheres 157.6
1889 Female, age 72, unknown 141.5
2583 Male, age 75, right hemisphere 136.0
1941 Male, age 53, unknown 135.8
2409 Female, age 72, unknown 135.8
2590 Female, age 75, unknown 131.6
2699 Male, age 18, unknown 131.6
2241 Male, age 72, unknown 118.2
Superior colliculus
nTPM: 137.7
2664 Male, age 75, both hemispheres 168.3
1796 Male, age 53, unknown 157.1
2668 Female, age 75, unknown 153.8
2261 Male, age 18, unknown 153.1
2087 Female, age 72, unknown 143.0
1995 Male, age 72, unknown 137.5
1839 Male, age 51, unknown 120.4
2587 Male, age 74, left hemisphere 120.2
1913 Female, age 42, unknown 118.5
1895 Male, age 76, right hemisphere 105.5
Ventral tegmental area
nTPM: 137.6
1915 Female, age 42, unknown 154.5
1942 Male, age 51, unknown 145.6
2021 Male, age 53, unknown 143.7
2410 Female, age 72, unknown 142.9
2218 Male, age 76, both hemispheres 128.5
2223 Female, age 72, unknown 110.1

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

141.2
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 141.2
Samples: 139

Max nTPM: 403.2
Min nTPM: 57.9
Std nTPM: 46.4
Median nTPM: 132.2
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 403.2
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 313.9
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 297.6
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 285.5
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 276.8
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 246.2
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 239.0
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 225.2
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 221.4
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 212.2
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 205.0
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 201.6
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 192.0
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 186.0
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 180.5
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 175.5
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 171.8
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 171.6
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 171.2
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 168.9
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 168.6
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 166.8
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 165.3
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 164.4
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 164.4
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 163.2
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 162.8
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 161.7
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 159.4
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 158.4
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 154.9
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 154.6
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 153.2
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 152.6
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 149.9
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 149.8
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 148.4
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 148.1
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 148.0
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 147.9
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 146.8
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 146.7
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 146.3
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 144.5
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 143.9
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 143.1
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 141.7
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 141.3
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 140.9
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 140.3
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 140.3
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 140.2
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 139.2
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 138.7
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 138.6
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 138.2
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 138.0
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 138.0
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 137.5
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 137.1
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 137.0
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 136.4
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 135.7
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 135.7
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 134.5
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 133.9
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 133.8
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 132.9
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 132.6
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 132.2
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 132.1
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 131.8
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 131.7
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 130.1
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 129.8
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 129.7
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 129.6
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 129.5
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 129.3
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 128.9
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 128.6
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 128.1
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 127.4
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 127.3
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 126.4
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 125.9
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 125.6
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 125.2
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 124.6
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 124.6
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 124.5
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 123.0
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 122.3
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 122.2
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 121.5
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 121.4
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 120.0
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 119.9
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 119.3
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 119.2
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 119.2
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 118.7
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 117.8
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 116.7
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 116.6
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 115.8
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 114.8
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 114.7
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 114.7
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 114.0
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 113.4
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 111.3
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 111.3
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 111.3
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 109.1
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 108.3
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 108.1
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 108.1
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 107.9
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 105.9
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 105.0
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 104.4
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 103.0
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 101.0
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 100.0
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 99.6
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 97.7
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 97.0
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 96.9
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 96.3
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 93.5
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 93.2
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 91.2
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 88.1
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 83.6
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 79.9
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 76.0
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 75.5
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 57.9
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

58.0
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 58.0
FF:10158-103A5 76 years, female 58.0

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

118.3
Pig sample Sample description nTPM
Substantia nigra
nTPM: 105.7
Samples: 4

Max nTPM: 141.0
Min nTPM: 81.4
Sample A Female 141.0
Sample B Female 94.0
Sample C Male 106.4
Sample D Male 81.4
Midbrain
nTPM: 118.4
Samples: 4

Max nTPM: 174.7
Min nTPM: 82.8
Sample A Female 174.7
Sample B Female 97.0
Sample C Male 118.9
Sample D Male 82.8
Periaqueductal gray
nTPM: 92.7
Samples: 3

Max nTPM: 107.2
Min nTPM: 81.5
Sample B Female 89.5
Sample C Male 107.2
Sample D Male 81.5
Superior colliculi
nTPM: 102.5
Samples: 4

Max nTPM: 127.8
Min nTPM: 88.8
Sample A Female 127.8
Sample B Female 94.6
Sample C Male 98.8
Sample D Male 88.8

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

232.9
Mouse sample Sample description nTPM
Midbrain
nTPM: 232.9
Samples: 4

Max nTPM: 249.8
Min nTPM: 214.6
Sample A Male 249.8
Sample B Male 214.6
Sample C Female 219.2
Sample D Female 248.1

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

9.1
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 9.1
513 Antisense, RP_Baylor_102825, Mouse strain C57BL/6J (56 days, male) 9.1
512 Antisense, RP_Baylor_102825, Mouse strain C57BL/6J (56 days, male) 7.1

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