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On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.
Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.
If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.
h
m
l
n
Cholangiocytes:
Not detected
Hepatocytes:
Medium
RNA expressioni
A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.
The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.
Scroll down to view mRNA expression data in more detail.
Consensus:
113.7
nTPM
HPA:
99.8
nTPM
GTEx:
113.7
nTPM
FANTOM5:
213.0
Scaled Tags Per Million
LIVER - Antibody stainingi
Antibody staining in the annotated cell types in the current human tissue is reported as not detected, low, medium, or high, based on conventional immunohistochemistry profiling in selected tissues. This score is based on the combination of the staining intensity and fraction of stained cells.
Each image is clickable and will lead to virtual microscopy that enables deeper exploration of all samples and also displays staining intensity scores, fraction scores and subcellular localization as well as patient and tissue information for each sample.
Antibody HPA039901
Antibody HPA040006
Cholangiocytes
Not detected
Not detected
Hepatocytes
Medium
Medium
LIVER - HPA RNA-seqi
The RNA-seq details section shows detailed information about the individual samples used for the transcript profiling and results of the RNA-seq analysis.
Information about each individual sample is listed below, including gender, age, a tissue section image and estimated fractions of cell types. nTPM (normalized transcripts per million) values give a quantification of the gene abundance which is comparable between different genes and samples.
Average nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
99.8
Female, age 60
Liver sample 21 nTPM: 118.2
Male, age 54
Liver sample 23 nTPM: 115.4
Cell types%
Hepatocytes:
80
Fibroblasts:
15
Other cell types:
5
Male, age 74
Liver sample 24 nTPM: 101.9
Cell types%
Hepatocytes:
85
Fibroblasts:
5
Other cell types:
10
Female, age 62
Liver sample 350 nTPM: 62.8
Cell types%
Hepatocytes:
70
Fibroblasts:
10
Other cell types:
20
Male, age 78
Liver sample 351 nTPM: 80.6
Cell types%
Hepatocytes:
75
Fibroblasts:
5
Other cell types:
20
Male, age 53
Liver sample 352 nTPM: 91.1
Cell types%
Hepatocytes:
80
Fibroblasts:
5
Other cell types:
15
Male, age 77
Liver sample 353 nTPM: 92.2
Cell types%
Hepatocytes:
75
Fibroblasts:
5
Other cell types:
20
Female, age 72
Liver sample 359 nTPM: 139.5
Cell types%
Hepatocytes:
50
Fibroblasts:
10
Other cell types:
40
Male, age 70
Liver sample 367 nTPM: 93.2
Cell types%
Hepatocytes:
65
Fibroblasts:
10
Other cell types:
25
Female, age 23
Liver sample 396 nTPM: 103
Cell types%
Hepatocytes:
70
Fibroblasts:
5
Other cell types:
25
LIVER - GTEx RNA-seqi
RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.
Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
113.7
GTEx sample id
Sample description
nTPM
Liver Average nTPM: 113.7
Samples: 226
Max nTPM: 222.4
Min nTPM: 22.1
Std nTPM: 33.7
Median nTPM: 107.7
GTEX-1CB4J-0726-SM-7IGN8
60-69 years, male
222.4
GTEX-1JJ6O-0826-SM-CXZJL
60-69 years, male
216.0
GTEX-XXEK-1126-SM-4BRUX
50-59 years, male
214.3
GTEX-13PVQ-1526-SM-5IFEQ
50-59 years, male
200.4
GTEX-YFC4-1526-SM-5IFJS
40-49 years, female
198.0
GTEX-13NZ9-1326-SM-5MR3V
50-59 years, male
192.8
GTEX-12696-0826-SM-5EGGE
60-69 years, male
190.5
GTEX-1LH75-0926-SM-EAZ5C
50-59 years, female
178.6
GTEX-P78B-1326-SM-3P611
40-49 years, female
178.1
GTEX-13O1R-2026-SM-5KM3N
60-69 years, male
173.3
GTEX-1ICLY-1526-SM-C1YS4
50-59 years, male
172.8
GTEX-144GM-1326-SM-5LU5E
20-29 years, male
172.5
GTEX-145MF-0826-SM-5QGQA
50-59 years, male
172.3
GTEX-O5YT-0826-SM-3TW8N
20-29 years, male
171.7
GTEX-1EH9U-1126-SM-7IGLU
60-69 years, male
171.3
GTEX-131XE-0326-SM-5LZVO
50-59 years, male
170.4
GTEX-1KD5A-1226-SM-CXZK7
50-59 years, male
169.2
GTEX-1QP66-0226-SM-DPRXS
50-59 years, male
167.9
GTEX-QEL4-1226-SM-447A4
50-59 years, male
165.4
GTEX-132NY-0926-SM-5P9G3
60-69 years, male
165.0
GTEX-1K9T9-0726-SM-CXZJZ
50-59 years, female
164.8
GTEX-12KS4-1326-SM-5LUB3
30-39 years, male
163.9
GTEX-1GN73-1126-SM-9OSW5
60-69 years, male
163.4
GTEX-REY6-1226-SM-48FDR
60-69 years, male
160.0
GTEX-13N11-0926-SM-5IJG2
50-59 years, female
159.2
GTEX-ZTPG-1426-SM-51MT3
20-29 years, female
158.0
GTEX-139YR-0226-SM-5IFEM
50-59 years, male
157.7
GTEX-RU72-1426-SM-46MUF
50-59 years, female
152.7
GTEX-O5YV-0726-SM-EV798
60-69 years, female
152.6
GTEX-14C38-1526-SM-5RQJ7
50-59 years, male
152.5
GTEX-1HCU7-1726-SM-B2LX9
50-59 years, male
151.9
GTEX-148VI-0626-SM-5TDDH
60-69 years, female
151.5
GTEX-14JG1-1626-SM-664NH
40-49 years, male
149.9
GTEX-YB5E-0326-SM-5IFHU
40-49 years, male
149.1
GTEX-145MO-2326-SM-5NQ9K
60-69 years, male
148.8
GTEX-X4XY-1626-SM-46MVN
60-69 years, male
148.8
GTEX-ZYT6-0626-SM-5E45V
30-39 years, male
148.7
GTEX-139TS-1426-SM-5IFJD
60-69 years, male
145.1
GTEX-132AR-0426-SM-5IFH8
50-59 years, female
144.7
GTEX-U8XE-1526-SM-4E3HT
30-39 years, male
144.1
GTEX-S32W-1926-SM-4AD63
50-59 years, female
143.2
GTEX-1HBPI-1026-SM-AHZ4N
50-59 years, male
143.1
GTEX-WQUQ-1926-SM-4OOSA
60-69 years, male
141.6
GTEX-UTHO-2426-SM-4JBHD
60-69 years, male
141.2
GTEX-146FH-1526-SM-5NQBU
50-59 years, female
140.8
GTEX-VUSG-0126-SM-4KL1X
50-59 years, male
139.4
GTEX-15ER7-1826-SM-6LLI7
20-29 years, female
137.6
GTEX-131XH-0626-SM-5LZWH
50-59 years, male
137.4
GTEX-1NV8Z-1626-SM-DPRYT
60-69 years, male
137.0
GTEX-14DAQ-1726-SM-5S2R2
60-69 years, female
136.1
GTEX-RWSA-1426-SM-47JXA
40-49 years, male
136.0
GTEX-1GF9X-0426-SM-7MKHN
40-49 years, female
135.2
GTEX-13NYB-1026-SM-5IFH3
40-49 years, male
134.3
GTEX-14753-1626-SM-5NQ9L
60-69 years, male
133.5
GTEX-14E7W-1526-SM-6871X
70-79 years, male
133.5
GTEX-Y5LM-0426-SM-4VBRO
40-49 years, female
133.0
GTEX-13N2G-0926-SM-5IFGJ
60-69 years, male
132.6
GTEX-1S5VW-1826-SM-EAZ53
60-69 years, male
132.2
GTEX-11DXY-0526-SM-5EGGQ
60-69 years, male
132.1
GTEX-1B932-1426-SM-793AN
40-49 years, female
131.4
GTEX-P44G-1126-SM-3NM9D
30-39 years, male
131.2
GTEX-1JMLX-1326-SM-CXZJO
50-59 years, male
131.2
GTEX-1B8SG-1326-SM-79ONT
50-59 years, male
131.0
GTEX-S33H-1626-SM-4AD68
30-39 years, male
130.8
GTEX-X4EO-1126-SM-4QARQ
60-69 years, female
130.1
GTEX-12WSG-0626-SM-5FQTQ
50-59 years, female
129.7
GTEX-11TT1-1726-SM-5EQLJ
20-29 years, male
129.3
GTEX-11ZVC-0726-SM-5FQT9
50-59 years, female
129.1
GTEX-13FLV-0326-SM-5N9DJ
50-59 years, male
128.8
GTEX-1A32A-0826-SM-72D5C
50-59 years, female
128.5
GTEX-1GF9W-0826-SM-7MKHI
60-69 years, male
128.0
GTEX-1C6VQ-1626-SM-79OO1
50-59 years, male
127.7
GTEX-ZYY3-0626-SM-5NQ6W
60-69 years, female
126.5
GTEX-131YS-1626-SM-5HL6C
60-69 years, female
125.6
GTEX-WVLH-2126-SM-EYYWD
50-59 years, male
125.4
GTEX-13OW6-2626-SM-5IFF2
50-59 years, male
125.1
GTEX-1AX8Z-1026-SM-7189R
60-69 years, male
123.8
GTEX-1JJEA-1526-SM-CNNPK
60-69 years, male
123.8
GTEX-QEG4-1826-SM-CKZN9
30-39 years, male
123.8
GTEX-14XAO-0226-SM-68728
60-69 years, female
123.7
GTEX-17HGU-1826-SM-7IGQM
50-59 years, male
123.7
GTEX-1CB4F-1726-SM-7MGXH
60-69 years, male
123.5
GTEX-UPK5-1426-SM-4JBHH
40-49 years, male
123.3
GTEX-R53T-0326-SM-48FEC
50-59 years, female
123.0
GTEX-11ZTS-1426-SM-5EQMM
60-69 years, female
122.2
GTEX-Q734-0326-SM-48U15
40-49 years, female
119.8
GTEX-147F4-1426-SM-5LUA8
50-59 years, male
118.6
GTEX-1HB9E-0626-SM-AHZ4K
50-59 years, male
118.1
GTEX-WYVS-1926-SM-4PQZ2
40-49 years, female
118.0
GTEX-11TUW-1726-SM-5BC5C
60-69 years, male
117.0
GTEX-TKQ2-1726-SM-4DXUP
50-59 years, male
116.8
GTEX-13O3O-1826-SM-5IFGW
60-69 years, female
116.0
GTEX-1H11D-0826-SM-9OSWB
40-49 years, male
116.0
GTEX-18D9B-1526-SM-7KFRK
60-69 years, male
115.4
GTEX-1KAFJ-0726-SM-CXZKF
50-59 years, male
114.8
GTEX-14AS3-0126-SM-5Q5F4
40-49 years, female
114.5
GTEX-1BAJH-1526-SM-7RHGI
70-79 years, male
114.5
GTEX-144GL-1426-SM-79OMA
50-59 years, male
114.4
GTEX-YECK-1926-SM-4W21H
60-69 years, male
114.2
GTEX-1IKK5-0326-SM-C1YPY
60-69 years, male
114.1
GTEX-147JS-1126-SM-5RQIW
60-69 years, male
113.7
GTEX-13NZB-0626-SM-5IFH6
30-39 years, male
113.2
GTEX-1EN7A-2026-SM-7MGY4
40-49 years, male
112.8
GTEX-1KANB-2226-SM-DHXJW
50-59 years, male
112.5
GTEX-13SLX-1226-SM-5S2Q6
50-59 years, female
111.6
GTEX-1EKGG-1226-SM-7IGNO
60-69 years, male
111.5
GTEX-1QP6S-1326-SM-DPRZ8
40-49 years, male
111.4
GTEX-1GZ4I-1526-SM-9OSW9
50-59 years, male
111.3
GTEX-X4EP-1026-SM-4QAS5
60-69 years, female
111.2
GTEX-17HII-1026-SM-7IGLY
50-59 years, male
111.0
GTEX-139TU-0826-SM-5IJFG
60-69 years, male
109.3
GTEX-ZVT4-0626-SM-5E45T
50-59 years, female
108.0
GTEX-13PVR-0126-SM-5S2PY
60-69 years, female
107.9
GTEX-11NUK-1226-SM-5P9GM
50-59 years, male
107.5
GTEX-11NV4-1326-SM-5HL6V
60-69 years, male
107.5
GTEX-12WSD-1426-SM-5GCN9
60-69 years, female
106.2
GTEX-11WQC-0726-SM-5EQMR
60-69 years, male
106.0
GTEX-13VXU-0926-SM-5IFFH
50-59 years, male
105.9
GTEX-1GN2E-0926-SM-9WPOH
60-69 years, male
105.8
GTEX-X261-1726-SM-4PQYT
50-59 years, male
105.6
GTEX-1J8EW-1626-SM-C1YQ8
60-69 years, female
105.5
GTEX-13113-1326-SM-5GCOI
60-69 years, female
105.4
GTEX-14E1K-0326-SM-5S2PE
50-59 years, male
105.3
GTEX-1399R-1226-SM-5P9GF
30-39 years, male
105.1
GTEX-QDVN-0826-SM-48TZ2
50-59 years, male
104.6
GTEX-1269C-0626-SM-5FQSS
60-69 years, female
104.4
GTEX-18465-1626-SM-7LG6N
50-59 years, male
104.2
GTEX-13112-1426-SM-5EGH8
50-59 years, male
103.8
GTEX-1IKJJ-1526-SM-C1YSC
60-69 years, male
103.6
GTEX-PX3G-0826-SM-48TZS
20-29 years, female
103.4
GTEX-1A8FM-1226-SM-7IGMD
50-59 years, female
103.2
GTEX-13QJC-0726-SM-5RQJK
60-69 years, female
102.8
GTEX-1B996-1426-SM-7EPIA
60-69 years, male
102.5
GTEX-14PJO-1726-SM-68719
60-69 years, male
101.1
GTEX-QESD-2026-SM-447BI
20-29 years, male
101.0
GTEX-ZEX8-0826-SM-4WKHK
50-59 years, male
100.7
GTEX-RM2N-1926-SM-48FCU
50-59 years, male
100.2
GTEX-1A8G7-1126-SM-731ED
60-69 years, male
100.1
GTEX-1399T-0826-SM-5IFES
60-69 years, male
99.8
GTEX-Z9EW-0426-SM-5CVM9
40-49 years, male
99.6
GTEX-ZZPU-0426-SM-5GZYH
50-59 years, female
99.1
GTEX-1B8L1-0726-SM-7P8RT
60-69 years, male
98.6
GTEX-1212Z-0226-SM-59HLF
60-69 years, male
97.7
GTEX-1QCLZ-1226-SM-EAZ49
60-69 years, female
97.6
GTEX-1HBPH-2626-SM-A96TV
40-49 years, female
97.4
GTEX-15RJE-1126-SM-6LPI5
40-49 years, male
97.3
GTEX-1KWVE-0326-SM-EV7AF
30-39 years, male
96.8
GTEX-18A7A-1526-SM-72D69
50-59 years, female
96.2
GTEX-WY7C-0726-SM-4ONCB
50-59 years, male
95.9
GTEX-147GR-1326-SM-7IGLB
60-69 years, male
95.5
GTEX-WZTO-0626-SM-4PQYY
40-49 years, male
95.2
GTEX-18A6Q-2026-SM-718AQ
60-69 years, male
94.8
GTEX-11DXZ-0126-SM-5EGGY
50-59 years, male
94.7
GTEX-YEC4-0826-SM-5P9FV
40-49 years, male
94.2
GTEX-1GN1U-0926-SM-9WPPY
50-59 years, female
93.3
GTEX-1E2YA-1226-SM-7MGY3
50-59 years, male
92.9
GTEX-1QPFJ-1126-SM-E9U5V
30-39 years, female
92.9
GTEX-1GF9V-1226-SM-7MKGY
60-69 years, male
92.8
GTEX-QV44-0326-SM-C1YQX
50-59 years, male
92.8
GTEX-17EVP-1026-SM-7IGOZ
40-49 years, male
92.7
GTEX-1EWIQ-0726-SM-7MKFW
70-79 years, female
92.7
GTEX-RN64-1826-SM-48FDV
50-59 years, male
92.6
GTEX-RTLS-1326-SM-46MUN
60-69 years, female
92.6
GTEX-OIZF-0826-SM-3MJGO
60-69 years, male
92.2
GTEX-ZF2S-3026-SM-4WWCH
50-59 years, female
92.1
GTEX-X3Y1-2726-SM-4PQZH
40-49 years, male
91.9
GTEX-1R9JW-0826-SM-DPRZJ
30-39 years, female
91.7
GTEX-Y111-0726-SM-EYYVM
50-59 years, male
91.6
GTEX-1PIIG-1326-SM-EXOIR
30-39 years, male
91.2
GTEX-ZAB5-0426-SM-5CVMI
50-59 years, male
90.8
GTEX-15RJ7-2026-SM-6LPJ4
40-49 years, male
90.5
GTEX-ZPU1-0826-SM-57WG2
40-49 years, male
90.4
GTEX-11ZUS-2526-SM-59872
30-39 years, male
90.2
GTEX-12WSM-0726-SM-5GCOW
60-69 years, male
89.7
GTEX-SJXC-1226-SM-4DM78
60-69 years, male
89.7
GTEX-Y5V5-0926-SM-4VBPZ
60-69 years, female
89.6
GTEX-145LU-1326-SM-5LU9N
50-59 years, male
89.5
GTEX-1I1HK-1126-SM-AHZ2L
60-69 years, male
89.2
GTEX-14PHX-0526-SM-664NW
50-59 years, male
88.9
GTEX-18A66-2026-SM-7189C
60-69 years, male
88.9
GTEX-12WSI-0226-SM-5GCNA
50-59 years, male
88.7
GTEX-1HT8W-0826-SM-C1YRJ
30-39 years, male
88.7
GTEX-WFON-1726-SM-4LVMQ
40-49 years, male
88.5
GTEX-15DYW-1326-SM-6LPIV
60-69 years, female
88.2
GTEX-13FTW-1126-SM-5J2NV
40-49 years, male
88.0
GTEX-1CAMQ-1426-SM-7MKFL
40-49 years, male
87.9
GTEX-13FTZ-0726-SM-5IFFY
60-69 years, male
87.5
GTEX-ZVT3-1626-SM-5GU66
60-69 years, female
87.3
GTEX-1ICG6-1026-SM-B2LY6
70-79 years, female
87.1
GTEX-RNOR-1426-SM-48FDJ
50-59 years, female
86.0
GTEX-14BIL-1326-SM-79OMR
50-59 years, male
85.6
GTEX-11OF3-0726-SM-5BC4Z
60-69 years, male
83.9
GTEX-1RQEC-1126-SM-EAZ5E
60-69 years, male
83.3
GTEX-T6MN-1226-SM-3NMA5
50-59 years, male
82.5
GTEX-1PBJJ-0626-SM-DPRYO
30-39 years, male
82.5
GTEX-ZAB4-0826-SM-5LU9D
40-49 years, male
81.7
GTEX-1LGRB-0626-SM-CNNQH
50-59 years, female
81.3
GTEX-OOBJ-0826-SM-3NB2K
60-69 years, male
80.9
GTEX-1497J-0726-SM-5Q5D1
60-69 years, male
80.5
GTEX-XBEC-1526-SM-4AT68
50-59 years, male
79.6
GTEX-12WSL-0226-SM-5CVMJ
50-59 years, male
79.4
GTEX-1MJIX-0726-SM-DPRYP
40-49 years, male
78.8
GTEX-14A5I-1726-SM-5QGQ5
50-59 years, female
78.1
GTEX-ZVP2-0626-SM-51MSO
50-59 years, male
77.8
GTEX-1F75A-1626-SM-9JGGT
50-59 years, male
75.9
GTEX-15SZO-1226-SM-6LPIP
50-59 years, male
74.7
GTEX-17MF6-1126-SM-7DUFS
40-49 years, male
73.5
GTEX-13X6J-1826-SM-5TDCT
50-59 years, male
71.9
GTEX-1HCVE-1526-SM-B2LWW
50-59 years, male
71.5
GTEX-S4Z8-0526-SM-4AD4T
60-69 years, male
70.7
GTEX-ZF29-2026-SM-DNZYW
60-69 years, female
69.9
GTEX-Q2AG-1126-SM-48U1P
40-49 years, female
68.5
GTEX-1B933-1226-SM-731DW
50-59 years, female
66.6
GTEX-1S82Y-1026-SM-EV7BJ
40-49 years, male
66.3
GTEX-1KD4Q-1526-SM-D4P3L
40-49 years, male
63.1
GTEX-11GSP-0626-SM-5986T
60-69 years, female
62.9
GTEX-11EQ9-0526-SM-5A5JZ
30-39 years, male
62.2
GTEX-15SHU-1826-SM-7KUKS
40-49 years, female
58.0
GTEX-U3ZN-0226-SM-3DB8D
30-39 years, female
58.0
GTEX-17HHE-0126-SM-79398
50-59 years, male
55.4
GTEX-17F96-1226-SM-79OK2
70-79 years, male
54.9
GTEX-1I1GR-1526-SM-CNNQE
60-69 years, male
52.7
GTEX-1AMFI-0826-SM-731DV
50-59 years, female
52.6
GTEX-WK11-1326-SM-4OOSI
50-59 years, male
40.9
GTEX-1AX9I-1626-SM-72D5D
60-69 years, male
40.2
GTEX-12ZZZ-1326-SM-59HKW
60-69 years, male
22.1
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LIVER - FANTOM5 CAGEi
RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.
Max subtype Scaled Tags Per Millioni
Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.
The Human Protein Atlas project is funded
