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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:530.5 nTPM
HPA Brain:149.9 nTPM
GTEx:530.5 nTPM
FANTOM5:192.6 Scaled Tags Per Million
Pig:234.1 nTPM
Mouse:1407.1 nTPM
Allen mouse:7.3 Expression energy

MIDBRAIN - Annotated protein expression
Pending normal tissue analysis

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

149.9
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 117.9
2019 Male, age 18, unknown 146.3
2411 Female, age 72, unknown 141.4
1827 Male, age 72, unknown 137.6
1870 Female, age 42, unknown 127.3
1833 Male, age 53, unknown 112.3
2666 Male, age 74, left hemisphere 109.8
2219 Male, age 76, both hemispheres 104.5
1830 Male, age 51, unknown 102.6
2828 Female, age 72, unknown 99.9
2586 Male, age 75, left hemisphere 97.4
Dorsal raphe nucleus
nTPM: 134.5
2298 Female, age 72, unknown 169.2
1828 Male, age 53, unknown 138.1
2047 Male, age 72, unknown 132.5
2750 Male, age 76, both hemispheres 127.2
2016 Female, age 72, unknown 105.5
Inferior colliculus
nTPM: 141.4
2097 Female, age 72, unknown 175.2
1890 Male, age 53, unknown 152.4
1848 Female, age 42, unknown 126.6
2849 Male, age 72, unknown 111.6
Median raphe nucleus
nTPM: 126.4
2220 Male, age 76, midline 126.4
Periaquaductal grey, anterior
nTPM: 131.8
1947 Male, age 18, unknown 153.1
1795 Male, age 51, unknown 132.2
2502 Female, age 75, unknown 110.2
Periaquaductal grey, dorsal
nTPM: 112.5
2850 Male, age 76, both hemispheres 119.5
2464 Female, age 72, unknown 112.6
1831 Male, age 72, unknown 112.5
1840 Male, age 53, unknown 105.3
Periaquaductal grey, lateral
nTPM: 113.8
2272 Male, age 74, both hemispheres 138.6
2053 Male, age 18, unknown 109.4
2140 Male, age 76, both hemispheres 93.3
Pretectal area
nTPM: 149.9
1816 Male, age 51, unknown 201.0
2007 Male, age 72, unknown 191.4
1817 Female, age 42, unknown 185.8
1944 Female, age 72, unknown 170.8
1815 Male, age 53, unknown 160.2
2224 Female, age 72, unknown 154.8
2667 Female, age 75, unknown 151.0
2273 Male, age 74, both hemispheres 127.5
2316 Male, age 76, right hemisphere 107.6
2825 Male, age 18, unknown 106.6
2407 Male, age 75, both hemispheres 91.9
Red nucleus
nTPM: 132.5
1821 Female, age 72, unknown 177.5
2725 Female, age 75, unknown 176.2
2785 Male, age 18, unknown 140.6
2584 Male, age 75, left hemisphere 137.0
1865 Male, age 51, unknown 125.5
2823 Male, age 76, right hemisphere 124.3
2503 Female, age 72, unknown 124.1
1954 Female, age 42, unknown 122.7
2769 Male, age 72, unknown 117.4
2588 Male, age 74, left hemisphere 116.1
2227 Male, age 72, unknown 115.0
1904 Male, age 53, unknown 113.4
Substantia nigra
nTPM: 144.1
1889 Female, age 72, unknown 198.7
2241 Male, age 72, unknown 172.7
1916 Female, age 42, unknown 166.5
1851 Male, age 51, unknown 159.5
1941 Male, age 53, unknown 158.8
2665 Male, age 74, both hemispheres 128.9
2409 Female, age 72, unknown 125.5
2699 Male, age 18, unknown 115.0
2590 Female, age 75, unknown 114.0
2583 Male, age 75, right hemisphere 100.9
Superior colliculus
nTPM: 124.1
1796 Male, age 53, unknown 143.4
2087 Female, age 72, unknown 139.6
2261 Male, age 18, unknown 134.1
2668 Female, age 75, unknown 129.4
2587 Male, age 74, left hemisphere 129.1
1895 Male, age 76, right hemisphere 126.6
1913 Female, age 42, unknown 124.1
1839 Male, age 51, unknown 108.3
2664 Male, age 75, both hemispheres 103.6
1995 Male, age 72, unknown 103.1
Ventral tegmental area
nTPM: 134.9
2410 Female, age 72, unknown 169.7
2223 Female, age 72, unknown 145.8
1915 Female, age 42, unknown 143.0
2218 Male, age 76, both hemispheres 133.3
1942 Male, age 51, unknown 113.7
2021 Male, age 53, unknown 104.0

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

530.5
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 530.5
Samples: 139

Max nTPM: 1257.7
Min nTPM: 274.6
Std nTPM: 144.5
Median nTPM: 504.9
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 1257.7
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 1135.9
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 874.5
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 848.8
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 844.4
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 800.0
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 793.1
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 789.8
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 761.7
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 736.9
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 734.0
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 716.6
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 716.4
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 709.5
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 698.1
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 693.6
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 689.4
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 678.8
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 676.4
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 670.6
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 666.8
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 653.4
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 645.1
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 631.6
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 631.1
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 618.5
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 616.1
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 608.8
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 604.4
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 604.2
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 600.0
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 597.6
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 587.2
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 583.0
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 580.9
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 578.8
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 577.7
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 576.8
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 573.5
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 572.0
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 571.3
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 571.2
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 571.2
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 568.3
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 568.0
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 563.7
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 563.1
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 560.8
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 560.0
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 558.0
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 551.8
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 550.7
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 550.1
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 546.9
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 542.5
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 541.9
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 541.1
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 541.0
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 534.0
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 533.6
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 529.2
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 526.4
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 526.3
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 522.2
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 518.7
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 514.3
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 512.3
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 507.9
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 507.4
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 504.9
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 504.7
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 502.7
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 500.5
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 499.9
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 499.0
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 496.6
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 496.4
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 495.5
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 494.9
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 494.0
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 493.3
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 490.4
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 485.5
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 483.9
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 483.9
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 481.9
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 478.3
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 477.9
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 476.2
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 474.9
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 474.1
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 473.0
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 471.7
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 471.2
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 470.5
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 470.1
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 469.8
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 463.9
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 463.1
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 461.7
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 447.7
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 431.3
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 430.6
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 428.7
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 428.4
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 426.9
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 426.4
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 426.2
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 423.1
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 422.5
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 422.3
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 420.0
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 418.9
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 418.6
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 416.7
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 414.0
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 408.1
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 400.4
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 393.8
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 389.5
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 389.3
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 389.1
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 380.9
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 379.9
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 378.0
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 376.2
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 372.5
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 370.1
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 365.7
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 360.9
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 353.3
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 347.3
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 340.5
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 335.8
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 321.4
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 310.7
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 309.1
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 302.5
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 274.6
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

192.6
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 192.6
FF:10158-103A5 76 years, female 192.6

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

234.1
Pig sample Sample description nTPM
Substantia nigra
nTPM: 194.8
Samples: 4

Max nTPM: 300.9
Min nTPM: 121.5
Sample A Female 300.9
Sample B Female 184.1
Sample C Male 172.8
Sample D Male 121.5
Midbrain
nTPM: 199.8
Samples: 4

Max nTPM: 219.2
Min nTPM: 180.1
Sample A Female 180.1
Sample B Female 191.8
Sample C Male 207.9
Sample D Male 219.2
Periaqueductal gray
nTPM: 149.5
Samples: 3

Max nTPM: 169.1
Min nTPM: 130.8
Sample B Female 148.5
Sample C Male 169.1
Sample D Male 130.8
Superior colliculi
nTPM: 234.1
Samples: 4

Max nTPM: 328.3
Min nTPM: 175.1
Sample A Female 328.3
Sample B Female 185.8
Sample C Male 247.3
Sample D Male 175.1

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

1407.1
Mouse sample Sample description nTPM
Midbrain
nTPM: 1407.1
Samples: 4

Max nTPM: 1519.6
Min nTPM: 1293.9
Sample A Male 1494.5
Sample B Male 1320.4
Sample C Female 1293.9
Sample D Female 1519.6

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

7.3
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 7.3
67862431 Antisense, RP_041018_01_C03, Mouse strain C57BL/6J (56 days, male) 7.3
68203444 Antisense, RP_041018_01_C03, Mouse strain C57BL/6J (56 days, male) 5.1

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