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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:746.1 nTPM
HPA Brain:716.0 nTPM
GTEx:746.1 nTPM
FANTOM5:62.9 Scaled Tags Per Million
Pig:337.4 nTPM
Mouse:266.6 nTPM
Allen mouse:9.6 Expression energy

MIDBRAIN - Annotated protein expression
Pending normal tissue analysis

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

716.0
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 616.9
2586 Male, age 75, left hemisphere 792.3
1870 Female, age 42, unknown 664.4
2411 Female, age 72, unknown 648.1
2666 Male, age 74, left hemisphere 644.9
1827 Male, age 72, unknown 634.2
2828 Female, age 72, unknown 628.3
1833 Male, age 53, unknown 567.4
1830 Male, age 51, unknown 552.9
2019 Male, age 18, unknown 529.0
2219 Male, age 76, both hemispheres 507.2
Dorsal raphe nucleus
nTPM: 646.5
2298 Female, age 72, unknown 727.6
2047 Male, age 72, unknown 649.4
2016 Female, age 72, unknown 638.9
2750 Male, age 76, both hemispheres 630.6
1828 Male, age 53, unknown 586.2
Inferior colliculus
nTPM: 624.0
2097 Female, age 72, unknown 664.3
1848 Female, age 42, unknown 626.8
1890 Male, age 53, unknown 618.7
2849 Male, age 72, unknown 586.2
Median raphe nucleus
nTPM: 589.0
2220 Male, age 76, midline 589.0
Periaquaductal grey, anterior
nTPM: 716.0
2502 Female, age 75, unknown 838.7
1947 Male, age 18, unknown 696.9
1795 Male, age 51, unknown 612.5
Periaquaductal grey, dorsal
nTPM: 593.5
1840 Male, age 53, unknown 706.5
2464 Female, age 72, unknown 590.6
1831 Male, age 72, unknown 578.4
2850 Male, age 76, both hemispheres 498.4
Periaquaductal grey, lateral
nTPM: 551.0
2053 Male, age 18, unknown 685.0
2272 Male, age 74, both hemispheres 494.2
2140 Male, age 76, both hemispheres 473.8
Pretectal area
nTPM: 576.9
1816 Male, age 51, unknown 612.8
2316 Male, age 76, right hemisphere 608.9
2825 Male, age 18, unknown 606.0
2224 Female, age 72, unknown 605.8
1817 Female, age 42, unknown 595.0
2407 Male, age 75, both hemispheres 590.8
2007 Male, age 72, unknown 589.1
1815 Male, age 53, unknown 586.3
1944 Female, age 72, unknown 542.6
2273 Male, age 74, both hemispheres 513.3
2667 Female, age 75, unknown 495.7
Red nucleus
nTPM: 628.8
1821 Female, age 72, unknown 708.6
2503 Female, age 72, unknown 703.4
2584 Male, age 75, left hemisphere 700.3
2769 Male, age 72, unknown 676.6
1865 Male, age 51, unknown 653.7
1904 Male, age 53, unknown 647.9
2227 Male, age 72, unknown 646.7
2588 Male, age 74, left hemisphere 595.6
2725 Female, age 75, unknown 585.5
1954 Female, age 42, unknown 583.9
2785 Male, age 18, unknown 535.5
2823 Male, age 76, right hemisphere 508.0
Substantia nigra
nTPM: 672.3
1851 Male, age 51, unknown 812.5
2665 Male, age 74, both hemispheres 725.0
1916 Female, age 42, unknown 697.0
2590 Female, age 75, unknown 688.9
2699 Male, age 18, unknown 678.8
2241 Male, age 72, unknown 644.4
1889 Female, age 72, unknown 629.0
2409 Female, age 72, unknown 622.6
1941 Male, age 53, unknown 613.6
2583 Male, age 75, right hemisphere 611.2
Superior colliculus
nTPM: 626.1
2664 Male, age 75, both hemispheres 750.5
2587 Male, age 74, left hemisphere 708.0
2261 Male, age 18, unknown 638.2
2668 Female, age 75, unknown 636.4
1839 Male, age 51, unknown 622.8
1796 Male, age 53, unknown 608.0
1913 Female, age 42, unknown 604.3
1995 Male, age 72, unknown 587.5
1895 Male, age 76, right hemisphere 557.5
2087 Female, age 72, unknown 548.3
Ventral tegmental area
nTPM: 668.9
2410 Female, age 72, unknown 727.2
2021 Male, age 53, unknown 705.6
1915 Female, age 42, unknown 690.9
2223 Female, age 72, unknown 658.9
1942 Male, age 51, unknown 635.1
2218 Male, age 76, both hemispheres 595.7

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

746.1
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 746.1
Samples: 139

Max nTPM: 1413.6
Min nTPM: 341.6
Std nTPM: 184.3
Median nTPM: 722.3
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 1413.6
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 1282.4
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 1242.1
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 1240.3
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 1182.7
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 1117.5
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 1116.5
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 1089.4
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 1021.1
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 1003.2
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 997.2
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 993.1
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 976.1
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 970.4
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 966.7
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 966.3
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 960.7
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 958.2
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 951.4
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 945.3
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 938.5
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 937.4
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 934.9
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 934.6
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 929.5
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 918.5
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 916.2
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 889.8
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 883.8
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 880.6
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 880.3
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 876.4
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 876.3
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 869.8
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 865.6
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 850.7
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 844.5
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 843.1
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 842.8
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 838.6
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 837.7
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 837.0
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 817.3
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 811.7
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 811.2
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 801.0
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 796.3
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 789.9
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 788.3
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 784.7
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 782.6
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 780.9
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 780.7
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 777.9
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 777.6
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 775.6
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 774.7
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 768.2
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 768.0
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 746.7
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 744.3
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 743.1
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 739.7
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 738.4
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 727.7
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 727.5
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 726.6
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 725.5
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 724.1
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 722.3
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 721.9
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 719.1
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 706.8
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 705.2
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 692.3
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 688.8
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 688.5
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 681.1
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 679.6
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 671.8
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 671.7
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 665.0
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 664.4
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 663.2
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 663.1
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 659.5
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 658.4
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 650.7
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 650.0
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 649.9
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 642.5
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 639.3
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 636.5
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 634.6
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 628.3
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 627.9
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 624.1
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 623.2
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 620.9
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 616.4
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 615.3
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 614.9
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 609.8
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 609.0
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 605.2
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 601.3
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 596.9
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 596.2
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 596.0
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 595.7
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 595.1
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 585.4
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 583.3
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 580.4
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 579.6
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 578.2
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 573.7
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 564.7
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 563.5
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 562.8
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 561.4
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 560.9
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 560.4
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 556.3
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 555.0
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 550.2
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 547.0
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 534.1
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 528.4
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 527.9
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 527.7
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 525.7
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 514.4
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 494.3
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 493.2
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 480.9
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 470.6
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 450.2
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 341.6
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

62.9
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 62.9
FF:10158-103A5 76 years, female 62.9

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

337.4
Pig sample Sample description nTPM
Substantia nigra
nTPM: 274.2
Samples: 4

Max nTPM: 339.5
Min nTPM: 225.7
Sample A Female 339.5
Sample B Female 256.2
Sample C Male 275.4
Sample D Male 225.7
Midbrain
nTPM: 318.4
Samples: 4

Max nTPM: 345.4
Min nTPM: 289.4
Sample A Female 334.8
Sample B Female 289.4
Sample C Male 345.4
Sample D Male 303.8
Periaqueductal gray
nTPM: 240.2
Samples: 3

Max nTPM: 273.5
Min nTPM: 208.3
Sample B Female 238.8
Sample C Male 273.5
Sample D Male 208.3
Superior colliculi
nTPM: 337.4
Samples: 4

Max nTPM: 368.4
Min nTPM: 289.1
Sample A Female 368.4
Sample B Female 359.0
Sample C Male 332.9
Sample D Male 289.1

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

266.6
Mouse sample Sample description nTPM
Midbrain
nTPM: 266.6
Samples: 4

Max nTPM: 291.2
Min nTPM: 231.5
Sample A Male 291.2
Sample B Male 258.6
Sample C Female 231.5
Sample D Female 285.1

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

9.6
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 9.6
69818299 Antisense, RP_050510_04_G12, Mouse strain C57BL/6J (56 days, male) 10.0
74882810 Antisense, RP_060315_04_H02, Mouse strain C57BL/6J (56 days, male) 9.2

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