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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:481.5 nTPM
HPA Brain:681.6 nTPM
GTEx:481.5 nTPM
FANTOM5:737.7 Scaled Tags Per Million
Pig:1123.6 nTPM
Mouse:70.8 nTPM
Allen mouse:2.2 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

681.6
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 537.1
2411 Female, age 72, unknown 682.7
1833 Male, age 53, unknown 659.1
1870 Female, age 42, unknown 658.3
1830 Male, age 51, unknown 649.6
2828 Female, age 72, unknown 587.7
2019 Male, age 18, unknown 539.1
1827 Male, age 72, unknown 424.1
2586 Male, age 75, left hemisphere 421.2
2666 Male, age 74, left hemisphere 379.9
2219 Male, age 76, both hemispheres 369.7
Dorsal raphe nucleus
nTPM: 414.2
2750 Male, age 76, both hemispheres 689.0
2016 Female, age 72, unknown 422.6
1828 Male, age 53, unknown 396.2
2298 Female, age 72, unknown 292.2
2047 Male, age 72, unknown 271.2
Inferior colliculus
nTPM: 388.1
2849 Male, age 72, unknown 434.2
1848 Female, age 42, unknown 412.2
1890 Male, age 53, unknown 384.4
2097 Female, age 72, unknown 321.7
Median raphe nucleus
nTPM: 415.4
2220 Male, age 76, midline 415.4
Periaquaductal grey, anterior
nTPM: 312.8
2502 Female, age 75, unknown 376.5
1947 Male, age 18, unknown 287.4
1795 Male, age 51, unknown 274.5
Periaquaductal grey, dorsal
nTPM: 322.1
2464 Female, age 72, unknown 412.5
1831 Male, age 72, unknown 348.2
2850 Male, age 76, both hemispheres 281.1
1840 Male, age 53, unknown 246.4
Periaquaductal grey, lateral
nTPM: 318.2
2053 Male, age 18, unknown 374.2
2272 Male, age 74, both hemispheres 330.4
2140 Male, age 76, both hemispheres 250.0
Pretectal area
nTPM: 383.8
2667 Female, age 75, unknown 532.9
1815 Male, age 53, unknown 483.7
2316 Male, age 76, right hemisphere 431.7
2407 Male, age 75, both hemispheres 413.6
2825 Male, age 18, unknown 407.8
1817 Female, age 42, unknown 399.9
2273 Male, age 74, both hemispheres 348.9
2224 Female, age 72, unknown 334.9
2007 Male, age 72, unknown 332.6
1944 Female, age 72, unknown 283.4
1816 Male, age 51, unknown 252.3
Red nucleus
nTPM: 681.6
2823 Male, age 76, right hemisphere 838.6
2769 Male, age 72, unknown 823.3
2227 Male, age 72, unknown 778.8
1865 Male, age 51, unknown 774.0
1821 Female, age 72, unknown 762.6
1904 Male, age 53, unknown 755.8
1954 Female, age 42, unknown 665.5
2503 Female, age 72, unknown 656.9
2785 Male, age 18, unknown 641.4
2588 Male, age 74, left hemisphere 565.5
2584 Male, age 75, left hemisphere 498.5
2725 Female, age 75, unknown 418.4
Substantia nigra
nTPM: 392.0
2699 Male, age 18, unknown 504.6
2583 Male, age 75, right hemisphere 497.7
1851 Male, age 51, unknown 471.0
1889 Female, age 72, unknown 429.3
2409 Female, age 72, unknown 360.7
1941 Male, age 53, unknown 352.8
1916 Female, age 42, unknown 344.3
2590 Female, age 75, unknown 343.6
2665 Male, age 74, both hemispheres 314.7
2241 Male, age 72, unknown 300.9
Superior colliculus
nTPM: 447.7
1913 Female, age 42, unknown 644.9
1995 Male, age 72, unknown 623.0
2587 Male, age 74, left hemisphere 497.5
1839 Male, age 51, unknown 479.0
1895 Male, age 76, right hemisphere 468.8
2668 Female, age 75, unknown 449.1
1796 Male, age 53, unknown 388.3
2664 Male, age 75, both hemispheres 342.8
2087 Female, age 72, unknown 305.5
2261 Male, age 18, unknown 277.7
Ventral tegmental area
nTPM: 491.7
2223 Female, age 72, unknown 793.5
2410 Female, age 72, unknown 519.0
2218 Male, age 76, both hemispheres 436.0
1942 Male, age 51, unknown 409.5
2021 Male, age 53, unknown 399.5
1915 Female, age 42, unknown 392.8

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

481.5
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 481.5
Samples: 139

Max nTPM: 1226.0
Min nTPM: 131.9
Std nTPM: 193.9
Median nTPM: 454.2
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 1226.0
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 1200.3
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 989.7
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 917.5
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 885.9
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 884.6
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 864.0
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 813.9
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 811.7
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 805.6
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 793.4
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 784.0
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 770.5
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 769.0
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 766.6
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 763.0
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 746.7
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 722.2
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 689.4
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 684.3
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 657.0
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 642.7
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 640.1
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 627.5
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 618.2
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 616.7
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 614.9
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 614.0
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 599.8
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 593.5
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 582.4
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 580.8
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 573.9
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 572.3
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 561.6
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 548.4
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 546.9
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 545.5
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 545.1
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 544.4
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 541.5
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 535.9
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 535.8
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 532.2
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 531.1
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 528.2
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 524.3
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 517.1
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 514.4
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 513.5
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 511.0
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 510.2
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 509.3
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 509.3
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 505.6
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 501.5
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 498.8
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 491.0
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 490.7
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 487.1
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 485.8
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 483.2
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 480.2
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 478.4
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 476.0
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 475.2
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 474.6
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 459.5
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 456.5
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 454.2
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 445.3
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 444.8
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 440.7
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 440.0
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 435.5
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 435.0
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 432.1
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 430.1
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 429.4
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 425.4
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 422.8
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 419.0
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 413.9
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 406.5
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 405.3
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 404.6
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 403.0
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 392.5
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 386.7
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 382.0
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 379.4
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 379.2
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 379.1
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 376.4
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 375.6
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 373.7
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 373.5
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 373.0
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 372.7
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 372.2
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 367.8
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 362.2
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 361.7
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 351.9
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 343.5
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 342.9
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 337.7
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 335.9
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 332.2
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 330.6
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 328.4
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 328.3
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 326.3
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 325.8
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 324.3
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 322.2
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 321.9
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 316.7
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 309.7
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 306.0
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 301.7
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 297.6
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 286.6
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 282.1
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 266.0
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 265.4
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 263.1
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 255.2
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 249.3
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 248.9
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 243.6
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 240.2
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 213.3
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 207.1
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 188.5
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 167.2
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 140.7
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 134.3
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 131.9
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

737.7
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 737.7
FF:10158-103A5 76 years, female 737.7

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

1123.6
Pig sample Sample description nTPM
Substantia nigra
nTPM: 726.8
Samples: 4

Max nTPM: 1253.1
Min nTPM: 350.2
Sample A Female 796.0
Sample B Female 350.2
Sample C Male 507.7
Sample D Male 1253.1
Midbrain
nTPM: 1123.6
Samples: 4

Max nTPM: 3065.5
Min nTPM: 376.1
Sample A Female 3065.5
Sample B Female 658.0
Sample C Male 394.8
Sample D Male 376.1
Periaqueductal gray
nTPM: 449.7
Samples: 3

Max nTPM: 506.3
Min nTPM: 364.5
Sample B Female 506.3
Sample C Male 364.5
Sample D Male 478.2
Superior colliculi
nTPM: 641.1
Samples: 4

Max nTPM: 802.9
Min nTPM: 363.9
Sample A Female 766.2
Sample B Female 363.9
Sample C Male 631.4
Sample D Male 802.9

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

70.8
Mouse sample Sample description nTPM
Midbrain
nTPM: 70.8
Samples: 4

Max nTPM: 78.1
Min nTPM: 62.0
Sample A Male 75.7
Sample B Male 62.0
Sample C Female 67.5
Sample D Female 78.1

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

2.2
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 2.2
671 Antisense, RP_Baylor_102908, Mouse strain C57BL/6J (56 days, male) 4.0
670 Antisense, RP_Baylor_102908, Mouse strain C57BL/6J (56 days, male) 2.9
672 Sense, RPS_Baylor_37014, Mouse strain C57BL/6J (56 days, male) 0.3

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