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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:47.9 nTPM
HPA Brain:288.4 nTPM
GTEx:47.9 nTPM
FANTOM5:6.3 Scaled Tags Per Million
Pig:100.2 nTPM
Mouse:98.8 nTPM
Allen mouse:15.6 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

288.4
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 144.2
2219 Male, age 76, both hemispheres 187.7
1827 Male, age 72, unknown 182.6
2828 Female, age 72, unknown 157.9
2019 Male, age 18, unknown 155.6
2586 Male, age 75, left hemisphere 145.6
2666 Male, age 74, left hemisphere 132.5
1833 Male, age 53, unknown 130.1
2411 Female, age 72, unknown 125.3
1830 Male, age 51, unknown 114.6
1870 Female, age 42, unknown 110.1
Dorsal raphe nucleus
nTPM: 116.3
2298 Female, age 72, unknown 137.2
2047 Male, age 72, unknown 124.5
1828 Male, age 53, unknown 116.9
2750 Male, age 76, both hemispheres 114.7
2016 Female, age 72, unknown 88.1
Inferior colliculus
nTPM: 171.0
2097 Female, age 72, unknown 183.4
1848 Female, age 42, unknown 177.3
2849 Male, age 72, unknown 175.1
1890 Male, age 53, unknown 148.4
Median raphe nucleus
nTPM: 148.4
2220 Male, age 76, midline 148.4
Periaquaductal grey, anterior
nTPM: 288.4
2502 Female, age 75, unknown 517.1
1795 Male, age 51, unknown 178.9
1947 Male, age 18, unknown 169.3
Periaquaductal grey, dorsal
nTPM: 133.6
1840 Male, age 53, unknown 154.8
2464 Female, age 72, unknown 143.5
2850 Male, age 76, both hemispheres 121.5
1831 Male, age 72, unknown 114.7
Periaquaductal grey, lateral
nTPM: 117.1
2140 Male, age 76, both hemispheres 145.7
2053 Male, age 18, unknown 119.7
2272 Male, age 74, both hemispheres 85.9
Pretectal area
nTPM: 199.4
2667 Female, age 75, unknown 381.1
1816 Male, age 51, unknown 293.4
2007 Male, age 72, unknown 249.2
1944 Female, age 72, unknown 240.0
1817 Female, age 42, unknown 227.8
1815 Male, age 53, unknown 186.0
2316 Male, age 76, right hemisphere 144.2
2224 Female, age 72, unknown 141.3
2825 Male, age 18, unknown 130.6
2407 Male, age 75, both hemispheres 128.7
2273 Male, age 74, both hemispheres 71.0
Red nucleus
nTPM: 108.0
2785 Male, age 18, unknown 162.3
2588 Male, age 74, left hemisphere 116.2
2823 Male, age 76, right hemisphere 115.5
2584 Male, age 75, left hemisphere 110.9
2769 Male, age 72, unknown 108.9
1821 Female, age 72, unknown 108.4
2227 Male, age 72, unknown 105.9
1954 Female, age 42, unknown 104.9
2503 Female, age 72, unknown 104.2
1865 Male, age 51, unknown 93.2
1904 Male, age 53, unknown 93.2
2725 Female, age 75, unknown 72.7
Substantia nigra
nTPM: 137.8
2665 Male, age 74, both hemispheres 231.8
1889 Female, age 72, unknown 195.7
1916 Female, age 42, unknown 187.5
1941 Male, age 53, unknown 166.7
1851 Male, age 51, unknown 150.9
2699 Male, age 18, unknown 115.9
2241 Male, age 72, unknown 109.1
2409 Female, age 72, unknown 103.1
2590 Female, age 75, unknown 80.9
2583 Male, age 75, right hemisphere 36.3
Superior colliculus
nTPM: 165.9
2664 Male, age 75, both hemispheres 258.1
1895 Male, age 76, right hemisphere 221.6
2087 Female, age 72, unknown 212.9
2261 Male, age 18, unknown 195.1
1796 Male, age 53, unknown 186.8
2587 Male, age 74, left hemisphere 149.5
1839 Male, age 51, unknown 148.9
1913 Female, age 42, unknown 105.5
1995 Male, age 72, unknown 101.8
2668 Female, age 75, unknown 79.4
Ventral tegmental area
nTPM: 134.8
2218 Male, age 76, both hemispheres 180.9
2410 Female, age 72, unknown 146.5
1915 Female, age 42, unknown 146.1
1942 Male, age 51, unknown 137.8
2223 Female, age 72, unknown 101.8
2021 Male, age 53, unknown 95.6

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

47.9
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 47.9
Samples: 139

Max nTPM: 225.7
Min nTPM: 0.6
Std nTPM: 40.5
Median nTPM: 37.6
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 225.7
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 164.5
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 140.3
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 136.1
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 124.8
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 121.0
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 119.5
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 115.9
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 114.4
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 112.0
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 108.3
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 107.3
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 104.6
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 104.5
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 103.7
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 103.5
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 103.3
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 100.8
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 99.5
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 98.5
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 93.7
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 93.0
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 90.6
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 90.3
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 86.4
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 86.2
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 82.6
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 81.0
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 80.9
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 79.2
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 79.1
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 77.4
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 77.1
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 76.1
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 74.5
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 74.2
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 73.3
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 73.2
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 71.4
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 68.6
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 67.5
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 66.4
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 64.8
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 64.1
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 63.6
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 62.5
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 62.1
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 61.3
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 59.5
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 58.9
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 58.3
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 58.2
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 57.6
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 55.0
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 53.8
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 53.2
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 53.0
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 51.7
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 49.3
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 49.1
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 49.0
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 47.4
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 43.5
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 41.7
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 40.3
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 39.1
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 38.9
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 38.8
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 38.3
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 37.6
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 36.0
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 35.6
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 34.7
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 34.3
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 33.4
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 33.1
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 32.2
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 29.9
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 28.2
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 27.7
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 27.4
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 27.4
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 27.0
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 23.0
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 22.8
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 22.8
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 22.6
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 21.4
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 21.3
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 21.3
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 21.3
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 20.9
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 20.6
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 19.4
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 19.3
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 18.6
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 18.4
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 16.5
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 16.2
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 16.0
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 15.9
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 15.5
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 15.0
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 14.5
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 14.1
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 13.2
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 13.1
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 12.6
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 12.4
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 11.8
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 11.8
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 11.4
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 9.8
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 9.6
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 9.2
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 8.8
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 8.0
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 7.9
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 7.8
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 7.6
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 7.5
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 7.4
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 7.2
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 6.3
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 5.6
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 5.0
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 4.5
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 4.3
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 3.9
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 3.5
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 3.0
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 2.8
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 2.6
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 2.2
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 1.7
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 1.6
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 1.4
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 0.7
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 0.6
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

6.3
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 6.3
FF:10158-103A5 76 years, female 6.3

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

100.2
Pig sample Sample description nTPM
Substantia nigra
nTPM: 63.0
Samples: 4

Max nTPM: 95.6
Min nTPM: 18.6
Sample A Female 94.3
Sample B Female 43.5
Sample C Male 95.6
Sample D Male 18.6
Midbrain
nTPM: 96.5
Samples: 4

Max nTPM: 193.2
Min nTPM: 16.5
Sample A Female 16.5
Sample B Female 48.2
Sample C Male 193.2
Sample D Male 128.1
Periaqueductal gray
nTPM: 63.5
Samples: 3

Max nTPM: 86.1
Min nTPM: 51.1
Sample B Female 51.1
Sample C Male 86.1
Sample D Male 53.3
Superior colliculi
nTPM: 100.2
Samples: 4

Max nTPM: 137.9
Min nTPM: 38.5
Sample A Female 107.1
Sample B Female 38.5
Sample C Male 137.9
Sample D Male 117.3

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

98.8
Mouse sample Sample description nTPM
Midbrain
nTPM: 98.8
Samples: 4

Max nTPM: 108.8
Min nTPM: 90.6
Sample A Male 90.6
Sample B Male 95.8
Sample C Female 108.8
Sample D Female 99.9

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

15.6
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 15.6
79556694 Antisense, RP_071204_01_C09, Mouse strain C57BL/6J (56 days, male) 18.9
79632316 Antisense, RP_071204_01_C09, Mouse strain C57BL/6J (56 days, male) 18.9
1585 Antisense, RP_040526_01_F03, Mouse strain C57BL/6J (56 days, male) 12.3
1586 Antisense, RP_040526_01_F03, Mouse strain C57BL/6J (56 days, male) 8.9

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