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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:179.0 nTPM
HPA Brain:75.3 nTPM
GTEx:179.0 nTPM
FANTOM5:125.0 Scaled Tags Per Million
Pig:350.2 nTPM
Mouse:355.0 nTPM
Allen mouse:0.2 Expression energy

MIDBRAIN - Annotated protein expression
Pending normal tissue analysis

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

75.3
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 59.1
2019 Male, age 18, unknown 84.6
2586 Male, age 75, left hemisphere 66.3
1827 Male, age 72, unknown 63.0
2411 Female, age 72, unknown 58.8
1870 Female, age 42, unknown 57.2
2219 Male, age 76, both hemispheres 55.6
2828 Female, age 72, unknown 54.7
1833 Male, age 53, unknown 53.3
1830 Male, age 51, unknown 49.7
2666 Male, age 74, left hemisphere 47.5
Dorsal raphe nucleus
nTPM: 65.8
2298 Female, age 72, unknown 76.9
1828 Male, age 53, unknown 71.6
2047 Male, age 72, unknown 67.0
2750 Male, age 76, both hemispheres 59.4
2016 Female, age 72, unknown 54.0
Inferior colliculus
nTPM: 68.9
1890 Male, age 53, unknown 81.5
2097 Female, age 72, unknown 75.5
1848 Female, age 42, unknown 63.5
2849 Male, age 72, unknown 55.2
Median raphe nucleus
nTPM: 59.6
2220 Male, age 76, midline 59.6
Periaquaductal grey, anterior
nTPM: 61.8
1947 Male, age 18, unknown 65.8
1795 Male, age 51, unknown 61.3
2502 Female, age 75, unknown 58.2
Periaquaductal grey, dorsal
nTPM: 55.4
2850 Male, age 76, both hemispheres 60.5
1831 Male, age 72, unknown 56.5
1840 Male, age 53, unknown 54.5
2464 Female, age 72, unknown 50.1
Periaquaductal grey, lateral
nTPM: 55.5
2272 Male, age 74, both hemispheres 62.5
2140 Male, age 76, both hemispheres 53.0
2053 Male, age 18, unknown 51.1
Pretectal area
nTPM: 74.2
1817 Female, age 42, unknown 101.8
2007 Male, age 72, unknown 99.2
1816 Male, age 51, unknown 89.6
1944 Female, age 72, unknown 88.7
2667 Female, age 75, unknown 74.2
1815 Male, age 53, unknown 72.3
2273 Male, age 74, both hemispheres 64.4
2224 Female, age 72, unknown 64.3
2316 Male, age 76, right hemisphere 56.4
2407 Male, age 75, both hemispheres 56.3
2825 Male, age 18, unknown 49.5
Red nucleus
nTPM: 69.9
1821 Female, age 72, unknown 93.5
2725 Female, age 75, unknown 79.2
2785 Male, age 18, unknown 78.5
2503 Female, age 72, unknown 71.3
1865 Male, age 51, unknown 70.6
2227 Male, age 72, unknown 68.9
2769 Male, age 72, unknown 68.5
1954 Female, age 42, unknown 68.0
2823 Male, age 76, right hemisphere 66.1
1904 Male, age 53, unknown 64.4
2588 Male, age 74, left hemisphere 59.1
2584 Male, age 75, left hemisphere 50.7
Substantia nigra
nTPM: 75.3
1916 Female, age 42, unknown 99.9
1851 Male, age 51, unknown 87.6
1889 Female, age 72, unknown 85.6
2409 Female, age 72, unknown 81.8
1941 Male, age 53, unknown 80.8
2241 Male, age 72, unknown 68.0
2699 Male, age 18, unknown 67.4
2665 Male, age 74, both hemispheres 67.3
2590 Female, age 75, unknown 60.8
2583 Male, age 75, right hemisphere 53.3
Superior colliculus
nTPM: 62.9
2087 Female, age 72, unknown 71.2
2587 Male, age 74, left hemisphere 70.9
2668 Female, age 75, unknown 68.6
1796 Male, age 53, unknown 67.6
1895 Male, age 76, right hemisphere 66.2
2261 Male, age 18, unknown 61.9
1913 Female, age 42, unknown 59.6
2664 Male, age 75, both hemispheres 56.6
1995 Male, age 72, unknown 54.8
1839 Male, age 51, unknown 51.6
Ventral tegmental area
nTPM: 66.7
1915 Female, age 42, unknown 79.8
2410 Female, age 72, unknown 75.6
2218 Male, age 76, both hemispheres 69.2
1942 Male, age 51, unknown 62.9
2223 Female, age 72, unknown 61.7
2021 Male, age 53, unknown 50.9

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

179.0
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 179.0
Samples: 139

Max nTPM: 320.2
Min nTPM: 78.7
Std nTPM: 47.1
Median nTPM: 174.1
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 320.2
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 313.0
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 309.7
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 293.8
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 286.7
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 277.8
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 270.3
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 266.1
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 263.7
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 261.4
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 260.9
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 260.7
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 257.1
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 246.4
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 245.2
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 244.8
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 237.9
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 236.8
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 236.4
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 231.2
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 231.1
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 228.2
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 223.8
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 218.9
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 218.1
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 217.6
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 215.6
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 212.6
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 211.8
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 211.4
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 209.4
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 206.8
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 202.4
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 199.0
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 198.2
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 195.6
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 194.4
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 193.8
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 193.4
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 192.6
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 189.0
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 187.4
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 187.2
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 186.7
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 185.9
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 185.8
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 185.7
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 184.8
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 184.4
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 183.5
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 182.5
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 182.0
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 181.8
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 180.9
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 180.1
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 179.9
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 179.1
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 179.1
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 178.9
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 178.8
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 178.7
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 177.1
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 177.0
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 175.8
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 175.7
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 175.5
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 175.3
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 174.3
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 174.2
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 174.1
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 173.8
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 173.3
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 173.1
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 173.0
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 172.8
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 172.5
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 172.2
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 172.0
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 170.8
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 170.5
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 169.6
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 168.6
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 168.5
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 168.5
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 167.9
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 167.6
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 166.3
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 165.6
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 164.1
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 163.0
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 162.5
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 162.2
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 162.1
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 161.5
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 160.3
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 160.3
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 159.9
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 155.5
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 155.2
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 151.1
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 150.1
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 149.4
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 148.2
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 146.7
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 146.3
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 146.2
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 145.8
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 143.4
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 143.3
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 141.4
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 140.4
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 140.3
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 139.7
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 139.6
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 138.4
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 138.1
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 137.1
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 134.9
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 133.7
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 133.4
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 132.0
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 131.9
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 131.6
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 131.0
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 129.1
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 124.7
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 122.7
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 122.0
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 115.7
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 115.1
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 115.0
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 111.5
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 110.1
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 104.2
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 101.1
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 94.2
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 89.6
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 84.2
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 78.7
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

125.0
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 125.0
FF:10158-103A5 76 years, female 125.0

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

350.2
Pig sample Sample description nTPM
Substantia nigra
nTPM: 276.8
Samples: 4

Max nTPM: 423.2
Min nTPM: 186.4
Sample A Female 423.2
Sample B Female 238.1
Sample C Male 259.3
Sample D Male 186.4
Midbrain
nTPM: 280.9
Samples: 4

Max nTPM: 300.9
Min nTPM: 253.5
Sample A Female 284.7
Sample B Female 284.5
Sample C Male 300.9
Sample D Male 253.5
Periaqueductal gray
nTPM: 214.0
Samples: 3

Max nTPM: 225.2
Min nTPM: 201.1
Sample B Female 215.6
Sample C Male 225.2
Sample D Male 201.1
Superior colliculi
nTPM: 350.2
Samples: 4

Max nTPM: 446.8
Min nTPM: 281.8
Sample A Female 446.8
Sample B Female 282.3
Sample C Male 389.7
Sample D Male 281.8

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

355.0
Mouse sample Sample description nTPM
Midbrain
nTPM: 355.1
Samples: 4

Max nTPM: 423.0
Min nTPM: 288.5
Sample A Male 423.0
Sample B Male 316.3
Sample C Female 288.5
Sample D Female 392.4

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

0.2
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 0.2
71763957 Antisense, RP_050921_02_H08, Mouse strain C57BL/6J (56 days, male) 0.2

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