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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:65.9 nTPM
HPA Brain:129.3 nTPM
GTEx:65.9 nTPM
FANTOM5:182.3 Scaled Tags Per Million
Mouse:38.1 nTPM
Allen mouse:0.3 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

129.3
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 104.1
1830 Male, age 51, unknown 142.8
1833 Male, age 53, unknown 134.6
1870 Female, age 42, unknown 127.5
2019 Male, age 18, unknown 127.4
2411 Female, age 72, unknown 126.0
2828 Female, age 72, unknown 89.2
2586 Male, age 75, left hemisphere 81.8
2666 Male, age 74, left hemisphere 79.0
1827 Male, age 72, unknown 74.2
2219 Male, age 76, both hemispheres 58.1
Dorsal raphe nucleus
nTPM: 84.8
2750 Male, age 76, both hemispheres 118.9
2016 Female, age 72, unknown 85.9
1828 Male, age 53, unknown 83.5
2298 Female, age 72, unknown 73.9
2047 Male, age 72, unknown 61.9
Inferior colliculus
nTPM: 68.9
1848 Female, age 42, unknown 81.7
2849 Male, age 72, unknown 71.2
1890 Male, age 53, unknown 69.9
2097 Female, age 72, unknown 52.6
Median raphe nucleus
nTPM: 87.3
2220 Male, age 76, midline 87.3
Periaquaductal grey, anterior
nTPM: 67.4
2502 Female, age 75, unknown 82.8
1947 Male, age 18, unknown 63.5
1795 Male, age 51, unknown 56.0
Periaquaductal grey, dorsal
nTPM: 66.6
2850 Male, age 76, both hemispheres 81.7
2464 Female, age 72, unknown 72.8
1831 Male, age 72, unknown 63.2
1840 Male, age 53, unknown 48.9
Periaquaductal grey, lateral
nTPM: 78.6
2272 Male, age 74, both hemispheres 87.7
2053 Male, age 18, unknown 77.3
2140 Male, age 76, both hemispheres 70.8
Pretectal area
nTPM: 73.9
1815 Male, age 53, unknown 90.8
2407 Male, age 75, both hemispheres 90.4
2273 Male, age 74, both hemispheres 88.4
2316 Male, age 76, right hemisphere 83.9
1817 Female, age 42, unknown 79.2
2224 Female, age 72, unknown 76.3
2825 Male, age 18, unknown 75.6
2007 Male, age 72, unknown 72.0
2667 Female, age 75, unknown 66.0
1944 Female, age 72, unknown 48.9
1816 Male, age 51, unknown 41.1
Red nucleus
nTPM: 129.3
1865 Male, age 51, unknown 172.7
1904 Male, age 53, unknown 150.2
2769 Male, age 72, unknown 145.6
1821 Female, age 72, unknown 144.8
2227 Male, age 72, unknown 144.7
2785 Male, age 18, unknown 133.5
2823 Male, age 76, right hemisphere 129.6
1954 Female, age 42, unknown 121.3
2503 Female, age 72, unknown 114.3
2584 Male, age 75, left hemisphere 106.4
2725 Female, age 75, unknown 95.6
2588 Male, age 74, left hemisphere 93.3
Substantia nigra
nTPM: 92.4
2590 Female, age 75, unknown 124.0
2699 Male, age 18, unknown 111.2
1851 Male, age 51, unknown 107.8
2583 Male, age 75, right hemisphere 104.5
2409 Female, age 72, unknown 96.9
1889 Female, age 72, unknown 84.6
2241 Male, age 72, unknown 78.4
2665 Male, age 74, both hemispheres 76.5
1916 Female, age 42, unknown 72.0
1941 Male, age 53, unknown 68.4
Superior colliculus
nTPM: 87.1
1913 Female, age 42, unknown 136.1
1995 Male, age 72, unknown 131.3
2587 Male, age 74, left hemisphere 106.5
1839 Male, age 51, unknown 88.8
1895 Male, age 76, right hemisphere 82.9
2664 Male, age 75, both hemispheres 72.6
1796 Male, age 53, unknown 71.0
2668 Female, age 75, unknown 70.9
2087 Female, age 72, unknown 59.8
2261 Male, age 18, unknown 50.9
Ventral tegmental area
nTPM: 97.5
2223 Female, age 72, unknown 131.4
2410 Female, age 72, unknown 108.6
2021 Male, age 53, unknown 95.8
2218 Male, age 76, both hemispheres 87.8
1915 Female, age 42, unknown 81.2
1942 Male, age 51, unknown 80.4

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

65.9
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 65.9
Samples: 139

Max nTPM: 154.4
Min nTPM: 19.3
Std nTPM: 23.2
Median nTPM: 61.3
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 154.4
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 130.9
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 124.3
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 121.6
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 119.1
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 115.8
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 115.8
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 113.3
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 111.6
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 110.6
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 109.7
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 103.6
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 103.3
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 101.7
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 101.6
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 98.3
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 93.7
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 91.5
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 90.3
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 87.0
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 86.4
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 86.4
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 86.0
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 85.5
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 85.2
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 84.2
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 83.0
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 82.0
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 81.1
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 79.9
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 79.4
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 78.8
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 78.4
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 78.1
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 78.0
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 77.0
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 76.8
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 76.2
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 76.0
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 75.0
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 74.8
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 74.7
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 74.4
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 74.0
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 71.8
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 71.5
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 71.1
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 71.0
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 71.0
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 70.8
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 70.7
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 70.0
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 68.6
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 68.4
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 67.2
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 64.5
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 64.2
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 64.0
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 63.6
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 63.6
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 63.2
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 63.1
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 63.1
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 62.8
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 62.8
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 62.7
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 62.5
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 62.0
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 61.4
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 61.3
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 61.2
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 61.0
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 60.2
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 60.0
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 59.6
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 58.9
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 58.5
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 58.2
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 57.0
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 56.7
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 56.6
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 56.5
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 56.3
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 56.0
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 55.9
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 55.6
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 55.5
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 55.4
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 54.3
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 54.3
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 54.2
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 53.9
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 53.9
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 53.5
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 53.3
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 53.2
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 52.8
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 52.6
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 52.4
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 51.9
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 51.8
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 51.7
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 51.1
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 50.5
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 50.1
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 50.0
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 48.7
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 48.4
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 47.8
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 47.3
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 47.3
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 47.1
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 46.8
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 45.8
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 45.4
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 45.4
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 44.9
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 44.4
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 44.0
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 43.8
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 43.5
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 43.3
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 42.5
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 42.0
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 40.9
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 40.5
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 40.3
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 40.2
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 39.3
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 39.3
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 39.1
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 39.0
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 38.6
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 38.2
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 34.7
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 32.7
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 29.3
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 25.9
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 19.3
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MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

182.3
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 182.3
FF:10158-103A5 76 years, female 182.3

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

38.1
Mouse sample Sample description nTPM
Midbrain
nTPM: 38.2
Samples: 4

Max nTPM: 42.9
Min nTPM: 35.1
Sample A Male 42.9
Sample B Male 37.4
Sample C Female 35.1
Sample D Female 37.2

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

0.3
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 0.3
68269586 Antisense, RP_041129_01_H03, Mouse strain C57BL/6J (56 days, male) 0.3

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