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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:503.1 nTPM
HPA Brain:136.8 nTPM
GTEx:503.1 nTPM
FANTOM5:34.0 Scaled Tags Per Million
Pig:388.1 nTPM
Mouse:728.6 nTPM
Allen mouse:9.7 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

136.8
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 119.7
1870 Female, age 42, unknown 148.7
2666 Male, age 74, left hemisphere 145.7
2411 Female, age 72, unknown 133.3
1833 Male, age 53, unknown 119.8
2219 Male, age 76, both hemispheres 118.0
1827 Male, age 72, unknown 115.1
1830 Male, age 51, unknown 112.3
2828 Female, age 72, unknown 108.3
2019 Male, age 18, unknown 100.8
2586 Male, age 75, left hemisphere 95.3
Dorsal raphe nucleus
nTPM: 121.6
2298 Female, age 72, unknown 134.7
2016 Female, age 72, unknown 132.0
2750 Male, age 76, both hemispheres 129.6
1828 Male, age 53, unknown 107.5
2047 Male, age 72, unknown 104.4
Inferior colliculus
nTPM: 127.5
2849 Male, age 72, unknown 134.3
1848 Female, age 42, unknown 129.4
1890 Male, age 53, unknown 126.8
2097 Female, age 72, unknown 119.4
Median raphe nucleus
nTPM: 130.1
2220 Male, age 76, midline 130.1
Periaquaductal grey, anterior
nTPM: 121.2
2502 Female, age 75, unknown 140.0
1947 Male, age 18, unknown 113.9
1795 Male, age 51, unknown 109.7
Periaquaductal grey, dorsal
nTPM: 126.6
1840 Male, age 53, unknown 151.2
2850 Male, age 76, both hemispheres 127.4
2464 Female, age 72, unknown 115.2
1831 Male, age 72, unknown 112.5
Periaquaductal grey, lateral
nTPM: 120.7
2140 Male, age 76, both hemispheres 129.6
2053 Male, age 18, unknown 124.7
2272 Male, age 74, both hemispheres 107.9
Pretectal area
nTPM: 110.4
2224 Female, age 72, unknown 133.8
2316 Male, age 76, right hemisphere 133.7
2825 Male, age 18, unknown 127.9
1817 Female, age 42, unknown 113.8
1815 Male, age 53, unknown 113.6
2007 Male, age 72, unknown 104.5
2667 Female, age 75, unknown 101.6
1816 Male, age 51, unknown 101.4
1944 Female, age 72, unknown 96.3
2273 Male, age 74, both hemispheres 95.4
2407 Male, age 75, both hemispheres 92.9
Red nucleus
nTPM: 126.9
2503 Female, age 72, unknown 170.8
1821 Female, age 72, unknown 140.5
1865 Male, age 51, unknown 137.0
2227 Male, age 72, unknown 129.5
2725 Female, age 75, unknown 127.7
2769 Male, age 72, unknown 124.0
1904 Male, age 53, unknown 123.1
2588 Male, age 74, left hemisphere 119.9
1954 Female, age 42, unknown 119.4
2823 Male, age 76, right hemisphere 111.5
2584 Male, age 75, left hemisphere 110.0
2785 Male, age 18, unknown 109.5
Substantia nigra
nTPM: 126.8
2241 Male, age 72, unknown 155.2
2699 Male, age 18, unknown 154.1
1851 Male, age 51, unknown 149.3
2665 Male, age 74, both hemispheres 144.2
2409 Female, age 72, unknown 134.5
2590 Female, age 75, unknown 121.2
1916 Female, age 42, unknown 115.6
1941 Male, age 53, unknown 106.5
1889 Female, age 72, unknown 105.4
2583 Male, age 75, right hemisphere 81.6
Superior colliculus
nTPM: 120.6
2587 Male, age 74, left hemisphere 149.7
1913 Female, age 42, unknown 140.7
1839 Male, age 51, unknown 127.5
1995 Male, age 72, unknown 125.7
1796 Male, age 53, unknown 118.4
2261 Male, age 18, unknown 114.4
2668 Female, age 75, unknown 112.4
1895 Male, age 76, right hemisphere 110.4
2664 Male, age 75, both hemispheres 107.6
2087 Female, age 72, unknown 99.0
Ventral tegmental area
nTPM: 136.8
2223 Female, age 72, unknown 154.0
2021 Male, age 53, unknown 147.7
1915 Female, age 42, unknown 137.3
2410 Female, age 72, unknown 134.7
2218 Male, age 76, both hemispheres 124.6
1942 Male, age 51, unknown 122.8

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

503.1
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 503.1
Samples: 139

Max nTPM: 1717.7
Min nTPM: 211.2
Std nTPM: 197.4
Median nTPM: 473.4
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 1717.7
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 995.9
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 992.8
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 948.6
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 931.5
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 921.4
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 815.8
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 814.4
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 782.2
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 773.3
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 773.2
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 758.5
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 754.2
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 748.8
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 736.7
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 728.2
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 727.7
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 712.9
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 712.4
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 703.7
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 697.9
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 683.0
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 675.6
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 666.4
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 663.1
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 657.6
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 639.3
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 635.5
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 622.3
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 619.4
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 618.6
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 609.4
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 602.6
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 596.5
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 581.7
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 579.6
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 577.7
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 575.1
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 574.7
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 573.8
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 570.8
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 566.7
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 563.1
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 560.8
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 559.6
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 553.8
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 550.4
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 549.5
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 549.4
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 538.9
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 530.9
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 523.7
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 521.4
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 520.0
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 516.8
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 512.8
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 504.1
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 502.4
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 496.1
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 488.6
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 488.1
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 487.3
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 484.8
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 484.6
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 479.5
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 477.0
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 476.7
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 476.0
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 474.4
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 473.4
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 466.9
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 457.8
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 457.4
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 457.4
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 455.7
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 455.3
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 449.7
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 448.3
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 447.6
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 444.9
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 441.3
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 439.9
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 439.1
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 435.1
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 428.3
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 419.5
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 405.5
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 404.0
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 402.6
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 402.4
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 402.3
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 399.6
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 392.5
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 392.4
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 385.6
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 377.3
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 374.2
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 373.1
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 372.2
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 372.0
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 369.4
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 368.4
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 365.1
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 363.6
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 363.0
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 360.3
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 358.3
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 356.7
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 356.1
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 352.6
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 350.7
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 349.0
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 348.0
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 343.7
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 343.3
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 340.1
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 338.7
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 338.4
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 332.0
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 330.3
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 328.3
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 320.6
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 317.9
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 307.3
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 297.5
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 293.1
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 290.5
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 289.4
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 289.0
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 280.6
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 279.1
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 278.8
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 277.9
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 273.5
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 266.5
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 255.9
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 234.9
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 234.0
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 211.2
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

34.0
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 34.0
FF:10158-103A5 76 years, female 34.0

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

388.1
Pig sample Sample description nTPM
Substantia nigra
nTPM: 388.2
Samples: 4

Max nTPM: 444.3
Min nTPM: 363.2
Sample A Female 444.3
Sample B Female 378.5
Sample C Male 363.2
Sample D Male 366.6
Midbrain
nTPM: 381.8
Samples: 4

Max nTPM: 541.0
Min nTPM: 286.5
Sample A Female 541.0
Sample B Female 410.7
Sample C Male 289.1
Sample D Male 286.5
Periaqueductal gray
nTPM: 323.3
Samples: 3

Max nTPM: 338.6
Min nTPM: 295.6
Sample B Female 335.6
Sample C Male 338.6
Sample D Male 295.6
Superior colliculi
nTPM: 379.2
Samples: 4

Max nTPM: 423.4
Min nTPM: 340.8
Sample A Female 423.4
Sample B Female 406.4
Sample C Male 340.8
Sample D Male 346.3

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

728.6
Mouse sample Sample description nTPM
Midbrain
nTPM: 728.6
Samples: 4

Max nTPM: 751.6
Min nTPM: 693.5
Sample A Male 751.6
Sample B Male 741.9
Sample C Female 727.3
Sample D Female 693.5

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

9.7
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 9.7
69873295 Antisense, RP_050510_04_H12, Mouse strain C57BL/6J (56 days, male) 9.7

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