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CANCER OVARIAN CANCER Show tissue menu
BREAST CANCER CARCINOID CERVICAL CANCER COLORECTAL CANCER ENDOMETRIAL CANCER GLIOMA HEAD AND NECK CANCER LIVER CANCER LUNG CANCER LYMPHOMA
MELANOMA OVARIAN CANCER PANCREATIC CANCER PROSTATE CANCER RENAL CANCER SKIN CANCER STOMACH CANCER TESTIS CANCER THYROID CANCER UROTHELIAL CANCER
OV TCGA OV VALIDATION PROTEIN OV CPTAC PROTEIN EXPRESSION
ANTIBODIES
AND
VALIDATION
Dictionary
Ovarian cancer
Human cancer
Ovary serous cystadenocarcinoma
OVARY SEROUS CYSTADENOCARCINOMA (TCGA) - Interactive survival scatter ploti

The Survival Scatter plot shows the clinical status (i.e. dead or alive) for all individuals in the patient cohort, based on the same data that underlies the corresponding Kaplan-Meier plots. Patients that are alive at last time for follow-up are shown in blue and patients who have died during the study are shown in red.

The x-axis shows the expression levels (FPKM) of the investigated gene in the tumor tissue at the time of diagnosis. The y-axis shows the follow-up time after diagnosis (years). Both axes are complimented with kernel density curves demonstrating the data density over the axes. The top density plot shows the expression levels (FPKM) distribution among dead (red) and alive patients (blue). The right density plot shows the data density of the survived years of dead patients with high and low expression levels respectively, stratified using the cutoff indicated by the vertical dashed line through the Survival Scatter plot. This cutoff is automatically defined based on the FPKM cutoff that minimizes the p-score. The cutoff can be changed by dragging the vertical line or by entering a cutoff value in the square labeled "Current cut-off".

Under the Survival Scatter plot the p-score landscape (black curve; left axis) is shown together with dead median separation (red curve; right axis). Dead median separation is the difference in median mRNA expression between patients who have died with high and low expression, respectively. It is calculated as follows: median FPKM expression of dead patients with high expression - median FPKM expression of dead patients with low expression. This is intended to aid the user in visually exploring custom cutoffs and the associated p-scores and dead median separation.

Individual patient data is displayed and can be filtered by clicking on one or more of the category buttons on the top of the page. Categories describing expression level and patient information include: high, low, alive, dead, female, male and tumor stages. The scale of the x-axis can be toggled between linear and log-scale by clicking on the "x log" button. Mouse-over function shows TCGA ID, patient information and mRNA expression (FPKM) for each patient.

& Survival analysisi

Kaplan-Meier plots summarize results from analysis of correlation between mRNA expression level and patient survival. Patients were divided based on level of expression into one of the two groups "low" (under cut off) or "high" (over cut off). X-axis shows time for survival (years) and y-axis shows the probability of survival, where 1.0 corresponds to 100 percent.

RPS4X is not prognostic in Ovary Serous Cystadenocarcinoma (TCGA)


Stage:

Survival analysis
Current cut offi

Current cut-off shows the cut-off (FPKM) currently selected. It may be changed manually. When the current cut-off is changed, the vertical dashed line indicating cut-off, the interactive survival scatter plot and the Kaplan-Meier curve will be automatically adjusted to show results accordingly.

:
Best expression cut offi

Based on the FPKM value of each gene, patients were classified into two groups and association between prognosis (survival) and gene expression (FPKM) was examined. The best expression cut-off refers the FPKM value that yields maximal difference with regard to survival between the two groups at the lowest log-rank P-value. Best expression cut-off was selected based on survival analysis .

When clicking on this number, the vertical dashed line indicating cut-off, the interactive survival plot, and the Kaplan-Meier curve will be adjusted to show results based on the best expression cut-off.

: 1520.81
Median expressioni

Median expression refers to the median FPKM value calculated based on the gene expression (FPKM) data from all patients in this dataset. When clicking on this number, the vertical dashed line indicating cut-off, the interactive survival plot, and the Kaplan-Meier curve will be adjusted to show results based on the median expression.

: N/A
Median follow up timei

Median follow up time refers to the median time (years) after diagnosis with this type of cancer, based on clinical data from all patients in this dataset.

: N/A
P scorei

Log-rank P value for Kaplan-Meier plot showing results from analysis of correlation between mRNA expression level and patient survival.

N/A
5-year survival highi

5-year survival for patients with higher expression than the expression cutoff.

For melanoma and glioma, 3-year survival is shown.

N/A
5-year survival lowi

5-year survival for patients with lower expression than the expression cutoff.

For melanoma and glioma, 3-year survival is shown.

N/A
TCGA RNA samplesi

RNA-seq data is reported as average FPKM (number Fragments Per Kilobase of exon per Million reads), generated by the The Cancer Genome Atlas (TCGA) .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. FPKM values of the individual samples are presented next to the box plot.

Average pTPM 1785.4
Number of samples 349
Samples
Sample Description pTPM
TCGA-25-2393-01A 81 years, female, white, stage:Stage IIIC, dead, 1157 days 6334.9
TCGA-04-1519-01A 48 years, female, stage:Stage IIIC, alive, 24 days 6087.6
TCGA-25-1632-01A 68 years, female, white, stage:Stage IV, dead, 1799 days 5469.8
TCGA-24-1846-01A 45 years, female, stage:Stage IIIC, alive, 133 days 5035.6
TCGA-25-1316-01A 55 years, female, white, stage:Stage IIIC, dead, 1279 days 5014.3
TCGA-09-1669-01A 54 years, female, white, stage:Stage IIIA, alive, 928 days 4516.2
TCGA-09-2054-01A 58 years, female, black or african american, stage:Stage IIIC, dead, 637 days 4126.1
TCGA-36-1577-01A 43 years, female, asian, stage:Stage IIC, alive, 783 days 4060.0
TCGA-61-2110-01A 56 years, female, white, stage:Stage IIIC, dead, 1354 days 4029.6
TCGA-13-0885-01A 70 years, female, white, stage:Stage IIIC, alive, 3388 days 3943.2
TCGA-10-0928-01A 71 years, female, white, stage:Stage IIIC, dead, 563 days 3923.2
TCGA-13-0727-01A 71 years, female, white, stage:Stage IIIC, dead, 462 days 3892.0
TCGA-23-1024-01A 52 years, female, white, stage:Stage IV, alive, 468 days 3817.0
TCGA-25-1319-01A 73 years, female, white, stage:Stage IIIC, dead, 1977 days 3659.2
TCGA-24-2038-01A 68 years, female, white, stage:Stage IIIA, dead, 1354 days 3637.5
TCGA-23-1113-01A 48 years, female, white, stage:Stage IV, dead, 949 days 3622.4
TCGA-09-1673-01A 50 years, female, white, stage:Stage IV, alive, 92 days 3487.1
TCGA-30-1891-01A 61 years, female, white, stage:Stage IIIC, dead, 914 days 3387.5
TCGA-57-1583-01A 57 years, female, black or african american, stage:Stage IIIC, dead, 346 days 3386.3
TCGA-09-1666-01A 57 years, female, white, stage:Stage IIIC, alive, 1752 days 3362.1
TCGA-24-0966-01A 78 years, female, black or african american, stage:Stage IIIC, alive, 232 days 3356.3
TCGA-61-1725-01A 40 years, female, white, stage:Stage IIIC, alive, 956 days 3305.8
TCGA-61-2008-01A 40 years, female, asian, stage:Stage IIC, alive, 932 days 3284.2
TCGA-29-1703-01A 56 years, female, black or african american, stage:Stage IIIC, dead, 1815 days 3284.0
TCGA-VG-A8LO-01A 55 years, female, black or african american, stage:Stage IV, dead, 24 days 3243.1
TCGA-25-1328-01A 38 years, female, white, stage:Stage IIIC, dead, 2009 days 3215.9
TCGA-13-A5FT-01A 67 years, female, black or african american, stage:Stage IIIC, alive, 2143 days 3202.4
TCGA-WR-A838-01A 72 years, female, black or african american, stage:Stage IIIC, dead, 304 days 3201.9
TCGA-13-1477-01A 49 years, female, white, stage:Stage IV, dead, 1662 days 3188.6
TCGA-61-2109-01A 40 years, female, white, stage:Stage IIIC, dead, 629 days 3175.2
TCGA-10-0927-01A 65 years, female, stage:Stage IIIC, dead, 2490 days 3152.4
TCGA-23-1027-01A 48 years, female, white, stage:Stage IIIC, dead, 976 days 3121.4
TCGA-29-1776-01A 63 years, female, black or african american, stage:Stage IIIC, alive, 360 days 3110.2
TCGA-61-1721-01A 38 years, female, white, stage:Stage IV, alive, 338 days 3103.4
TCGA-29-1768-01A 50 years, female, white, stage:Stage IV, dead, 952 days 3089.4
TCGA-25-2396-01A 71 years, female, white, stage:Stage IIIC, dead, 92 days 3082.9
TCGA-23-1028-01A 43 years, female, white, stage:Stage IIIC, alive, 1503 days 3053.7
TCGA-25-1631-01A 73 years, female, white, stage:Stage IIIC, dead, 9 days 3049.9
TCGA-61-1918-01A 45 years, female, white, stage:Stage IV, dead, 479 days 2984.4
TCGA-30-1861-01A 74 years, female, white, stage:Stage IIIC, dead, 1058 days 2979.4
TCGA-13-0883-01A 61 years, female, white, stage:Stage IIIC, dead, 2097 days 2972.7
TCGA-30-1714-01A 68 years, female, white, stage:Stage IV, dead, 1158 days 2968.4
TCGA-24-1565-01A 74 years, female, white, stage:Stage IIIC, dead, 312 days 2947.3
TCGA-29-1690-01A 66 years, female, white, stage:Stage IIIC, dead, 1448 days 2940.5
TCGA-13-0725-01A 44 years, female, white, stage:Stage IIIC, dead, 377 days 2917.7
TCGA-61-1728-01A 59 years, female, white, stage:Stage IV, alive, 848 days 2902.6
TCGA-13-1501-01A 50 years, female, white, stage:Stage IV, dead, 1314 days 2874.5
TCGA-13-0804-01A 73 years, female, white, stage:Stage IIIC, dead, 1073 days 2873.0
TCGA-23-1022-01A 67 years, female, white, stage:Stage IIIC, dead, 1511 days 2820.0
TCGA-13-1409-01A 73 years, female, white, stage:Stage IIIC, dead, 1742 days 2808.5
TCGA-61-2092-01A 57 years, female, white, stage:Stage IIIC, alive, 1573 days 2773.6
TCGA-61-2000-01A 67 years, female, white, stage:Stage IIIC, alive, 441 days 2726.1
TCGA-13-1404-01A 48 years, female, white, stage:Stage IIIC, alive, 2469 days 2722.2
TCGA-24-1567-01A 54 years, female, white, stage:Stage IIIB, dead, 524 days 2677.8
TCGA-13-1483-01A 61 years, female, white, stage:Stage IIIC, dead, 895 days 2640.8
TCGA-04-1514-01A 45 years, female, white, stage:Stage IIIA, dead, 1720 days 2616.7
TCGA-24-2267-01A 58 years, female, white, stage:Stage IIB, dead, 1446 days 2609.1
TCGA-25-1630-01A 73 years, female, white, stage:Stage IIIC, dead, 1162 days 2586.3
TCGA-04-1651-01A 53 years, female, white, stage:Stage IIIC, dead, 1102 days 2585.3
TCGA-29-1761-01A 80 years, female, asian, stage:Stage IIIC, dead, 528 days 2580.3
TCGA-13-0762-01A 65 years, female, white, stage:Stage IIIC, alive, 3400 days 2571.0
TCGA-24-1551-01A 53 years, female, white, stage:Stage IIIC, dead, 1579 days 2545.3
TCGA-36-1569-01A 52 years, female, white, stage:Stage IIIC, alive, 885 days 2521.7
TCGA-13-1408-01A 59 years, female, white, stage:Stage IIIC, dead, 1680 days 2511.5
TCGA-25-2400-01A 76 years, female, white, stage:Stage IIIC, dead, 1278 days 2511.4
TCGA-57-1584-01A 47 years, female, white, stage:Stage IIIC, alive, 643 days 2475.8
TCGA-61-1900-01A 51 years, female, black or african american, stage:Stage IIIB, alive, 176 days 2465.5
TCGA-59-2363-01A 40 years, female, asian, stage:Stage IIIA, alive, 165 days 2456.3
TCGA-24-1616-01A 56 years, female, white, stage:Stage IIIC, dead, 1163 days 2435.5
TCGA-36-1568-01A 52 years, female, stage:Stage IIIC, alive, 875 days 2387.8
TCGA-24-1923-01A 51 years, female, white, stage:Stage IIIC, dead, 690 days 2379.7
TCGA-59-A5PD-01A 55 years, female, black or african american, stage:Stage IC, dead, 624 days 2377.0
TCGA-10-0931-01A 44 years, female, white, stage:Stage IIIC, dead, 1000 days 2366.0
TCGA-29-1691-01A 51 years, female, white, stage:Stage IIIC, dead, 1470 days 2346.5
TCGA-29-1784-01A 55 years, female, white, stage:Stage IIIC, alive, 163 days 2314.3
TCGA-04-1362-01A 59 years, female, white, stage:Stage IIC, dead, 1348 days 2311.7
TCGA-29-1696-01A 43 years, female, white, stage:Stage IIIC, dead, 1032 days 2280.2
TCGA-23-1030-01A 64 years, female, white, stage:Stage IIIC, alive, 886 days 2277.3
TCGA-23-1111-01A 63 years, female, white, stage:Stage IIIC, alive, 98 days 2271.1
TCGA-24-2254-01A 66 years, female, white, stage:Stage IIIC, dead, 1736 days 2269.4
TCGA-24-2033-01A 87 years, female, white, stage:Stage IIIC, dead, 562 days 2258.0
TCGA-24-1467-01A 51 years, female, white, stage:Stage IIIC, dead, 3224 days 2246.6
TCGA-36-1574-01A 48 years, female, asian, stage:Stage IIIC, alive, 686 days 2223.2
TCGA-57-1582-01A 50 years, female, white, stage:Stage IIIC, dead, 731 days 2217.2
TCGA-09-1670-01A 57 years, female, white, stage:Stage IIIA, alive, 547 days 2192.4
TCGA-13-0730-01A 71 years, female, white, stage:Stage IIIC, dead, 542 days 2187.9
TCGA-61-2097-01A 71 years, female, white, stage:Stage IIC, alive, 1844 days 2159.6
TCGA-30-1853-01A 58 years, female, white, stage:Stage IIIC, dead, 1103 days 2159.1
TCGA-24-2293-01A 47 years, female, white, stage:'--, dead, 506 days 2147.4
TCGA-24-1546-01A 46 years, female, white, stage:Stage IIIC, dead, 1955 days 2127.8
TCGA-30-1718-01A 44 years, female, white, stage:Stage IIIC, dead, 1579 days 2116.1
TCGA-09-2048-01A 63 years, female, white, stage:Stage IIIC, dead, 138 days 2102.6
TCGA-23-1118-01A 45 years, female, white, stage:Stage IIIC, alive, 2616 days 2097.9
TCGA-31-1944-01A 47 years, female, white, stage:Stage IIIC, alive, 1386 days 2094.4
TCGA-13-0886-01A 67 years, female, white, stage:Stage IIIC, alive, 4665 days 2074.9
TCGA-24-1413-01A 51 years, female, white, stage:Stage IIIC, alive, 192 days 2073.9
TCGA-29-1783-01A 58 years, female, white, stage:Stage IIIC, alive, 220 days 2056.8
TCGA-59-2355-01A 58 years, female, white, stage:Stage IV, dead, 65 days 2056.0
TCGA-25-1870-01A 59 years, female, white, stage:Stage IIIC, dead, 455 days 2053.1
TCGA-04-1536-01A 60 years, female, black or african american, stage:Stage IV, dead, 885 days 2051.7
TCGA-61-1907-01A 63 years, female, white, stage:Stage IIIC, alive, 952 days 2007.1
TCGA-25-2409-01A 71 years, female, white, stage:Stage IV, dead, 821 days 2003.7
TCGA-36-1570-01A 49 years, female, white, stage:Stage IIIC, alive, 655 days 2003.7
TCGA-29-1777-01A 47 years, female, white, stage:Stage IIIC, alive, 374 days 1994.6
TCGA-24-1924-01A 65 years, female, white, stage:Stage IIIC, dead, 919 days 1982.6
TCGA-23-1119-01A 64 years, female, white, stage:Stage IIIC, alive, 3953 days 1970.7
TCGA-13-1489-01A 70 years, female, white, stage:Stage IIIC, dead, 2553 days 1962.6
TCGA-61-1998-01A 48 years, female, white, stage:Stage IIIC, alive, 168 days 1961.0
TCGA-24-2024-01A 72 years, female, black or african american, stage:Stage IIIC, dead, 1769 days 1958.2
TCGA-61-1724-01A 47 years, female, white, stage:Stage IIIC, dead, 637 days 1952.5
TCGA-13-1485-01A 48 years, female, white, stage:Stage IV, dead, 629 days 1949.2
TCGA-24-1428-01A 50 years, female, white, stage:Stage IIIC, alive, 529 days 1948.9
TCGA-24-1419-01A 62 years, female, white, stage:Stage IIIC, alive, 239 days 1925.2
TCGA-24-1544-01A 71 years, female, black or african american, stage:Stage IIIC, dead, 820 days 1924.8
TCGA-13-0724-01A 72 years, female, white, stage:Stage IV, dead, 83 days 1910.9
TCGA-24-1553-01A 53 years, female, white, stage:Stage IIIB, dead, 1767 days 1901.6
TCGA-04-1655-01A 49 years, female, white, stage:Stage IIIB, dead, 1380 days 1890.5
TCGA-24-1103-01A 50 years, female, black or african american, stage:Stage IIIC, dead, 1646 days 1886.7
TCGA-25-1877-01A 81 years, female, white, stage:Stage IIIC, dead, 730 days 1883.6
TCGA-23-1110-01A 42 years, female, white, stage:Stage IIIC, alive, 1658 days 1866.6
TCGA-04-1350-01A 46 years, female, white, stage:Stage IIIC, dead, 1946 days 1866.3
TCGA-24-1550-01A 49 years, female, white, stage:Stage IIIC, dead, 1249 days 1851.6
TCGA-24-1562-01A 67 years, female, white, stage:Stage IIIC, dead, 1384 days 1823.4
TCGA-24-1416-01A 34 years, female, white, stage:Stage IV, alive, 194 days 1817.5
TCGA-13-1510-01A 62 years, female, white, stage:Stage IIIC, dead, 1359 days 1797.0
TCGA-31-1959-01A 49 years, female, white, stage:Stage IV, alive, 67 days 1791.5
TCGA-24-2261-01A 76 years, female, white, stage:Stage IIIC, dead, 24 days 1780.4
TCGA-30-1866-01A 61 years, female, white, stage:Stage IV, dead, 1114 days 1779.2
TCGA-29-1762-01A 59 years, female, white, stage:Stage IV, dead, 2634 days 1776.9
TCGA-25-1329-01A 76 years, female, white, stage:Stage IIIC, dead, 457 days 1773.7
TCGA-13-1506-01A 45 years, female, white, stage:Stage IIIC, dead, 1039 days 1760.5
TCGA-13-1509-01A 64 years, female, white, stage:Stage IV, alive, 2438 days 1751.3
TCGA-04-1365-01A 87 years, female, white, stage:Stage IIIB, alive, 947 days 1750.2
TCGA-29-1769-01A 40 years, female, white, stage:Stage IIIC, alive, 699 days 1749.4
TCGA-24-1431-01A 67 years, female, white, stage:Stage IIIC, dead, 583 days 1738.3
TCGA-13-0766-01A 42 years, female, white, stage:Stage IIIC, dead, 1725 days 1735.5
TCGA-25-1322-01A 62 years, female, white, stage:Stage IV, dead, 91 days 1730.4
TCGA-24-1426-01A 43 years, female, white, stage:Stage IIIC, alive, 163 days 1727.1
TCGA-30-1892-01A 52 years, female, white, stage:Stage IIIC, dead, 1484 days 1720.0
TCGA-24-1604-01A 66 years, female, white, stage:Stage IIIC, dead, 2688 days 1713.8
TCGA-13-1487-01A 74 years, female, white, stage:Stage IV, dead, 681 days 1708.8
TCGA-20-1682-01A 56 years, female, white, stage:Stage IIIC, alive, 837 days 1700.6
TCGA-25-1326-01A 61 years, female, white, stage:Stage IIIC, dead, 1249 days 1699.6
TCGA-29-2425-01A 60 years, female, white, stage:Stage IIIC, alive, 1977 days 1680.8
TCGA-24-2290-01A 56 years, female, white, stage:Stage IIIC, dead, 1102 days 1676.6
TCGA-5X-AA5U-01A 61 years, female, black or african american, stage:Stage IIC, alive, 361 days 1675.1
TCGA-61-2002-01A 46 years, female, white, stage:Stage IIIC, alive, 547 days 1671.7
TCGA-29-2427-01A 60 years, female, white, stage:Stage IIIC, alive, 1900 days 1666.3
TCGA-57-1586-01A 66 years, female, white, stage:Stage IIIC, alive, 679 days 1662.1
TCGA-04-1356-01A 62 years, female, white, stage:Stage IIC, dead, 1499 days 1659.1
TCGA-13-0714-01A 55 years, female, white, stage:Stage IV, dead, 189 days 1655.3
TCGA-13-0720-01A 48 years, female, white, stage:Stage IIIC, dead, 1355 days 1648.5
TCGA-13-1496-01A 65 years, female, white, stage:Stage IIIC, dead, 129 days 1646.9
TCGA-24-1844-01A 64 years, female, white, stage:Stage IIIC, alive, 113 days 1640.2
TCGA-24-1474-01A 57 years, female, black or african american, stage:Stage IIIC, dead, 676 days 1638.3
TCGA-09-1662-01A 58 years, female, white, stage:Stage IV, dead, 2717 days 1634.5
TCGA-24-1464-01A 70 years, female, white, stage:Stage IIIC, dead, 379 days 1626.4
TCGA-23-1122-01A 53 years, female, white, stage:Stage IIIC, dead, 1189 days 1623.6
TCGA-24-1930-01A 53 years, female, white, stage:Stage IIIC, dead, 2467 days 1613.7
TCGA-23-1107-01A 59 years, female, white, stage:Stage IV, dead, 9 days 1611.9
TCGA-24-2271-01A 55 years, female, asian, stage:Stage IIIC, dead, 962 days 1609.1
TCGA-23-1109-01A 62 years, female, white, stage:Stage IIIC, dead, 1562 days 1607.9
TCGA-59-2354-01A 63 years, female, white, stage:Stage IIIC, dead, 1046 days 1599.1
TCGA-23-1123-01A 59 years, female, white, stage:Stage IIIC, dead, 1018 days 1597.0
TCGA-24-1435-01A 57 years, female, white, stage:Stage IIIC, dead, 1324 days 1592.0
TCGA-61-1919-01A 58 years, female, white, stage:Stage IIIC, dead, 1161 days 1590.7
TCGA-04-1361-01A 57 years, female, white, stage:Stage IIIB, alive, 989 days 1590.3
TCGA-29-1688-01A 39 years, female, white, stage:Stage IIIC, dead, 2400 days 1584.2
TCGA-04-1343-01A 72 years, female, white, stage:Stage IV, dead, 361 days 1580.9
TCGA-24-1558-01A 73 years, female, white, stage:Stage IIIC, dead, 594 days 1572.7
TCGA-24-2023-01A 54 years, female, white, stage:Stage IIIA, dead, 1364 days 1549.7
TCGA-09-0364-01A 80 years, female, white, stage:Stage IIC, dead, 887 days 1542.7
TCGA-31-1946-01A 30 years, female, stage:Stage IIIC, alive, 918 days 1539.9
TCGA-29-2414-01A 75 years, female, white, stage:Stage IIIC, dead, 2621 days 1535.9
TCGA-25-2401-01A 64 years, female, white, stage:Stage IIIC, dead, 90 days 1533.8
TCGA-24-0968-01A 59 years, female, white, stage:Stage IIIC, dead, 598 days 1532.5
TCGA-30-1860-01A 58 years, female, white, stage:Stage IIIC, dead, 1366 days 1532.4
TCGA-29-A5NZ-01A 66 years, female, black or african american, stage:Stage IIIC, dead, 1088 days 1532.1
TCGA-13-0765-01A 50 years, female, white, stage:Stage IIIC, dead, 1389 days 1522.0
TCGA-29-1770-01A 54 years, female, white, stage:Stage IIIC, alive, 741 days 1519.6
TCGA-13-1495-01A 60 years, female, white, stage:Stage IIIC, dead, 2749 days 1512.6
TCGA-61-2098-01A 62 years, female, white, stage:Stage IIIC, alive, 1993 days 1509.3
TCGA-24-1471-01A 60 years, female, white, stage:Stage IIIC, alive, 36 days 1507.5
TCGA-13-1505-01A 63 years, female, white, stage:Stage IIIC, alive, 1998 days 1505.2
TCGA-04-1347-01A 81 years, female, white, stage:Stage IV, alive, 1919 days 1500.5
TCGA-24-1845-01A 42 years, female, white, stage:Stage IIIC, alive, 116 days 1500.0
TCGA-29-1694-01A 45 years, female, white, stage:Stage IIIC, dead, 1187 days 1498.8
TCGA-24-1563-01A 66 years, female, black or african american, stage:Stage IIIC, dead, 1451 days 1496.3
TCGA-13-0795-01A 66 years, female, white, stage:Stage IIIC, dead, 619 days 1488.8
TCGA-29-1705-01A 47 years, female, white, stage:Stage IIIC, dead, 555 days 1484.8
TCGA-13-1403-01A 48 years, female, white, stage:Stage IIIC, dead, 2345 days 1483.7
TCGA-24-2280-01A 74 years, female, white, stage:Stage IIIC, alive, 2143 days 1483.5
TCGA-24-1424-01A 67 years, female, white, stage:Stage IIIC, alive, 183 days 1480.2
TCGA-23-2078-01A 66 years, female, white, stage:Stage IIIC, alive, 2661 days 1463.3
TCGA-59-2350-01A 44 years, female, stage:Stage IV, dead, 679 days 1453.0
TCGA-23-2084-01A 45 years, female, white, stage:Stage IV, dead, 1516 days 1452.4
TCGA-24-2281-01A 68 years, female, white, stage:Stage IIA, alive, 1357 days 1445.3
TCGA-61-1914-01A 65 years, female, stage:Stage IIIC, alive, 1722 days 1432.0
TCGA-10-0938-01A 80 years, female, white, stage:Stage IIIC, dead, 636 days 1418.0
TCGA-09-0366-01A 55 years, female, white, stage:Stage IIIC, dead, 1757 days 1416.7
TCGA-25-1321-01A 65 years, female, white, stage:Stage IIIC, dead, 1033 days 1416.4
TCGA-61-2101-01A 55 years, female, white, stage:Stage IIIC, dead, 1688 days 1414.0
TCGA-61-1910-01A 56 years, female, white, stage:Stage IIC, alive, 1127 days 1413.8
TCGA-09-2045-01A 50 years, female, asian, stage:Stage IV, dead, 1069 days 1411.9
TCGA-13-2060-01A 51 years, female, white, stage:Stage IV, alive, 2369 days 1411.4
TCGA-25-1323-01A 72 years, female, white, stage:Stage IIIC, dead, 395 days 1409.0
TCGA-24-1417-01A 54 years, female, white, stage:Stage IV, alive, 238 days 1408.4
TCGA-09-0367-01A 67 years, female, native hawaiian or other pacific islander, stage:Stage IIIC, dead, 547 days 1405.5
TCGA-04-1364-01A 61 years, female, white, stage:Stage IIIC, dead, 1024 days 1404.0
TCGA-04-1331-01A 78 years, female, white, stage:Stage IIIC, dead, 1336 days 1392.1
TCGA-36-1576-01A 76 years, female, stage:Stage IIIC, alive, 915 days 1375.6
TCGA-24-0979-01A 53 years, female, white, stage:Stage IV, dead, 1264 days 1375.5
TCGA-29-1701-01A 56 years, female, white, stage:Stage IIIC, dead, 515 days 1371.7
TCGA-25-1635-01A 71 years, female, white, stage:Stage IIIC, dead, 1583 days 1368.2
TCGA-24-2020-01A 67 years, female, white, stage:Stage IIIC, dead, 4624 days 1368.1
TCGA-29-1693-01A 72 years, female, white, stage:Stage IIIC, alive, 3096 days 1357.1
TCGA-24-1434-01A 59 years, female, white, stage:Stage IIIC, dead, 568 days 1356.5
TCGA-25-2398-01A 71 years, female, white, stage:Stage IIIC, dead, 1369 days 1346.1
TCGA-31-1951-01A 58 years, female, white, stage:Stage IIIC, alive, 684 days 1339.1
TCGA-30-1857-01A 64 years, female, white, stage:Stage IV, dead, 8 days 1335.2
TCGA-25-1315-01A 50 years, female, white, stage:Stage IIIC, dead, 1583 days 1327.0
TCGA-24-1560-01A 51 years, female, white, stage:Stage IIIC, dead, 1341 days 1319.4
TCGA-24-2036-01A 50 years, female, white, stage:Stage IIIA, dead, 1947 days 1314.0
TCGA-61-2111-01A 61 years, female, white, stage:Stage IV, alive, 3825 days 1313.2
TCGA-61-1738-01A 60 years, female, black or african american, stage:Stage IIIC, dead, 1089 days 1307.4
TCGA-13-0800-01A 52 years, female, white, stage:Stage IIIC, alive, 2661 days 1305.8
TCGA-29-1763-01A 43 years, female, black or african american, stage:Stage IIC, alive, 2032 days 1305.6
TCGA-13-1407-01A 51 years, female, white, stage:Stage IIIC, alive, 2534 days 1293.8
TCGA-10-0937-01A 44 years, female, white, stage:Stage IIIC, dead, 608 days 1290.1
TCGA-13-0887-01A 42 years, female, white, stage:Stage IIIC, dead, 2028 days 1289.3
TCGA-04-1542-01A 52 years, female, white, stage:Stage IIIB, dead, 2561 days 1286.5
TCGA-61-1737-01A 42 years, female, white, stage:Stage IV, alive, 1364 days 1277.2
TCGA-29-1774-01A 82 years, female, white, stage:Stage IIIC, alive, 527 days 1276.6
TCGA-25-2404-01A 38 years, female, american indian or alaska native, stage:Stage IIIC, dead, 883 days 1275.0
TCGA-61-2003-01A 53 years, female, white, stage:Stage IIIC, alive, 122 days 1269.4
TCGA-20-1687-01A 46 years, female, white, stage:Stage IV, alive, 81 days 1262.8
TCGA-13-0916-01A 49 years, female, white, stage:Stage IIIC, alive, 1785 days 1260.2
TCGA-24-2035-01A 65 years, female, white, stage:Stage IIIC, dead, 857 days 1257.5
TCGA-61-2009-01A 65 years, female, white, stage:Stage IIIC, alive, 1212 days 1255.4
TCGA-04-1530-01A 68 years, female, white, stage:Stage IIIC, dead, 3622 days 1247.6
TCGA-30-1862-01A 65 years, female, white, stage:Stage IV, dead, 186 days 1246.4
TCGA-36-1580-01A 82 years, female, stage:Stage IIIC, dead, 737 days 1245.0
TCGA-29-1785-01A 55 years, female, white, stage:Stage IIIC, dead, 1104 days 1244.6
TCGA-24-1430-01A 68 years, female, white, stage:Stage IIIC, dead, 863 days 1239.6
TCGA-13-1405-01A 49 years, female, white, stage:Stage IV, dead, 868 days 1229.0
TCGA-25-1320-01A 65 years, female, white, stage:Stage IIIC, dead, 1155 days 1225.7
TCGA-24-1928-01A 77 years, female, white, stage:Stage IIIC, dead, 336 days 1221.5
TCGA-59-2351-01A 51 years, female, white, stage:Stage IIIC, alive, 3532 days 1220.5
TCGA-20-0991-01A 78 years, female, white, stage:Stage IIB, alive, 797 days 1217.6
TCGA-13-1498-01A 73 years, female, white, stage:Stage IIIC, dead, 2012 days 1216.3
TCGA-24-1104-01A 56 years, female, white, stage:Stage IV, dead, 1933 days 1210.7
TCGA-57-1993-01A 56 years, female, white, stage:Stage IIIC, alive, 763 days 1204.5
TCGA-09-2051-01A 42 years, female, white, stage:Stage IIIC, alive, 1919 days 1195.8
TCGA-04-1332-01A 70 years, female, white, stage:Stage IIIC, dead, 1247 days 1192.4
TCGA-59-2348-01A 59 years, female, white, stage:Stage IIIC, alive, 5481 days 1188.1
TCGA-29-1711-01A 45 years, female, black or african american, stage:Stage IIIC, alive, 1053 days 1178.9
TCGA-23-1023-01A 65 years, female, white, stage:Stage IIIC, alive, 1233 days 1178.2
TCGA-04-1341-01A 85 years, female, white, stage:'--, alive, 33 days 1177.1
TCGA-24-1427-01A 58 years, female, stage:Stage IIIC, alive, 147 days 1168.2
TCGA-29-1778-01A 77 years, female, white, stage:Stage IIIC, alive, 454 days 1161.0
TCGA-31-1956-01A 60 years, female, white, stage:Stage IIIB, alive, 1342 days 1157.4
TCGA-04-1648-01A 57 years, female, white, stage:Stage IIIC, dead, 871 days 1156.3
TCGA-25-1634-01A 75 years, female, white, stage:Stage IIIC, dead, 1091 days 1151.4
TCGA-61-2012-01A 81 years, female, white, stage:Stage IIC, alive, 932 days 1146.4
TCGA-13-0924-01A 45 years, female, white, stage:Stage IV, alive, 2614 days 1143.5
TCGA-20-0987-01A 61 years, female, white, stage:Stage IIIC, dead, 701 days 1143.1
TCGA-29-2428-01A 58 years, female, white, stage:Stage IIIC, alive, 1372 days 1142.1
TCGA-31-1950-01A 76 years, female, white, stage:Stage IIIC, alive, 571 days 1139.5
TCGA-61-1741-01A 76 years, female, white, stage:Stage IIIB, dead, 1024 days 1133.1
TCGA-24-1557-01A 49 years, female, white, stage:Stage IIIC, dead, 1213 days 1133.0
TCGA-61-1995-01A 43 years, female, white, stage:Stage IIIC, alive, 61 days 1130.3
TCGA-29-1697-01A 62 years, female, white, stage:Stage IIIC, dead, 949 days 1130.1
TCGA-24-1847-01A 45 years, female, white, stage:Stage IV, alive, 343 days 1121.8
TCGA-25-2399-01A 80 years, female, white, stage:Stage IIIC, dead, 608 days 1119.3
TCGA-24-2289-01A 68 years, female, white, stage:Stage IV, dead, 2049 days 1119.2
TCGA-57-1585-01A 57 years, female, white, stage:Stage IIIC, dead, 53 days 1110.5
TCGA-OY-A56Q-01A 78 years, female, black or african american, stage:Stage IIA, alive, 576 days 1109.1
TCGA-24-0982-01A 77 years, female, white, stage:Stage IIIC, dead, 679 days 1108.6
TCGA-13-0906-01A 50 years, female, white, stage:Stage IIIC, alive, 3619 days 1087.8
TCGA-13-0920-01A 65 years, female, white, stage:Stage IIIC, dead, 1484 days 1087.3
TCGA-24-1105-01A 36 years, female, white, stage:Stage IIIC, dead, 1442 days 1085.1
TCGA-24-1843-01A 66 years, female, white, stage:Stage IIIC, alive, 106 days 1082.2
TCGA-24-1603-01A 53 years, female, white, stage:Stage IIIB, dead, 2742 days 1080.6
TCGA-20-1686-01A 75 years, female, white, stage:Stage IIIC, alive, 89 days 1068.9
TCGA-25-1633-01A 64 years, female, white, stage:Stage IIIC, dead, 1891 days 1063.8
TCGA-13-1410-01A 57 years, female, white, stage:Stage IV, alive, 2464 days 1058.4
TCGA-24-2027-01A 51 years, female, white, stage:Stage IV, dead, 3337 days 1045.1
TCGA-13-0923-01A 74 years, female, white, stage:Stage IIIC, alive, 2547 days 1044.2
TCGA-59-2352-01A 78 years, female, white, stage:Stage IIIC, dead, 286 days 1042.5
TCGA-24-1422-01A 82 years, female, black or african american, stage:Stage IIIC, dead, 23 days 1036.3
TCGA-29-1766-01A 74 years, female, white, stage:Stage IIIC, dead, 1199 days 1033.9
TCGA-24-2288-01A 70 years, female, white, stage:Stage IIIC, dead, 25 days 1032.0
TCGA-24-1842-01A 49 years, female, white, stage:Stage IIIC, alive, 253 days 1026.6
TCGA-13-1512-01A 49 years, female, white, stage:Stage IIIC, alive, 442 days 1021.7
TCGA-23-1116-01A 83 years, female, white, stage:Stage IIIC, dead, 592 days 1009.6
TCGA-25-1627-01A 73 years, female, white, stage:Stage IIIC, dead, 394 days 1007.7
TCGA-24-1850-01A 72 years, female, white, stage:Stage IIIC, alive, 168 days 996.2
TCGA-24-1423-01A 61 years, female, white, stage:Stage IIIC, alive, 190 days 983.2
TCGA-25-2392-01A 75 years, female, white, stage:Stage IV, dead, 31 days 973.0
TCGA-13-0911-01A 55 years, female, white, stage:Stage IV, dead, 1355 days 966.7
TCGA-36-1571-01A 53 years, female, white, stage:Stage IIIB, dead, 695 days 965.1
TCGA-13-0897-01A 54 years, female, white, stage:Stage IIIC, dead, 2182 days 959.2
TCGA-25-1317-01A 66 years, female, white, stage:Stage IIIC, dead, 61 days 957.0
TCGA-61-2088-01A 51 years, female, white, stage:Stage IIIC, alive, 145 days 953.1
TCGA-25-1626-01A 65 years, female, white, stage:Stage IIIC, dead, 518 days 950.3
TCGA-61-1911-01A 55 years, female, white, stage:Stage IIA, alive, 1293 days 947.6
TCGA-29-1710-01A 54 years, female, white, stage:Stage IIIC, dead, 951 days 940.2
TCGA-25-1313-01A 62 years, female, white, stage:Stage IV, dead, 820 days 933.9
TCGA-24-1425-01A 45 years, female, white, stage:Stage IIIC, alive, 181 days 931.6
TCGA-25-1623-01A 71 years, female, white, stage:Stage IV, dead, 565 days 931.6
TCGA-23-2077-01A 45 years, female, white, stage:Stage IIIC, alive, 3525 days 929.1
TCGA-25-2042-01A 60 years, female, american indian or alaska native, stage:Stage IIIC, dead, 396 days 924.4
TCGA-13-1499-01A 56 years, female, white, stage:Stage IIIC, alive, 3500 days 916.2
TCGA-23-1809-01A 63 years, female, white, stage:Stage IIC, alive, 16 days 903.8
TCGA-24-1549-01A 58 years, female, white, stage:Stage IIIB, dead, 1721 days 897.1
TCGA-31-1953-01A 52 years, female, asian, stage:Stage IIIC, alive, 204 days 895.8
TCGA-13-0726-01A 55 years, female, white, stage:Stage IIIC, dead, 949 days 895.2
TCGA-61-1733-01A 71 years, female, white, stage:Stage IIIC, alive, 967 days 888.7
TCGA-57-1994-01A 63 years, female, white, stage:'--, alive, 761 days 880.0
TCGA-13-1411-01A 81 years, female, white, stage:Stage IIIC, dead, 531 days 875.9
TCGA-24-1469-01A 71 years, female, white, stage:Stage IIIC, alive, 277 days 872.8
TCGA-13-0891-01A 73 years, female, white, stage:Stage IV, dead, 3128 days 872.4
TCGA-13-0888-01A 78 years, female, white, stage:Stage IIIC, dead, 2811 days 858.8
TCGA-29-1781-01A 69 years, female, white, stage:Stage IIIC, alive, 255 days 848.9
TCGA-13-0768-01A 73 years, female, white, stage:Stage IIIC, dead, 1784 days 824.9
TCGA-20-1683-01A 65 years, female, white, stage:Stage IIIC, alive, 772 days 824.5
TCGA-13-1507-01A 77 years, female, white, stage:Stage IIIC, dead, 1993 days 820.6
TCGA-24-1418-01A 68 years, female, white, stage:Stage IIIC, alive, 243 days 819.0
TCGA-25-1312-01A 69 years, female, white, stage:Stage IV, dead, 31 days 804.0
TCGA-29-1695-01A 62 years, female, white, stage:Stage IIIC, dead, 1229 days 792.8
TCGA-04-1338-01A 78 years, female, white, stage:Stage IIIC, alive, 1418 days 782.2
TCGA-13-1492-01A 66 years, female, white, stage:Stage IIIC, dead, 3819 days 777.7
TCGA-10-0933-01A 77 years, female, white, stage:Stage IIIC, dead, 446 days 769.2
TCGA-36-1581-01A 63 years, female, white, stage:Stage IIC, alive, 751 days 740.5
TCGA-24-1552-01A 77 years, female, white, stage:Stage IIIC, dead, 1259 days 737.6
TCGA-13-1511-01A 52 years, female, asian, stage:Stage IV, dead, 1650 days 730.9
TCGA-13-1488-01A 59 years, female, white, stage:Stage IV, dead, 2154 days 728.9
TCGA-25-1628-01A 67 years, female, white, stage:Stage IIIC, dead, 627 days 723.1
TCGA-09-0369-01A 56 years, female, white, stage:Stage IIIC, dead, 1082 days 713.1
TCGA-13-0797-01A 49 years, female, white, stage:Stage IIIC, alive, 2121 days 696.0
TCGA-23-1120-01A 60 years, female, white, stage:Stage IIIC, alive, 130 days 695.3
TCGA-24-2026-01A 79 years, female, white, stage:Stage IIIC, dead, 1059 days 683.1
TCGA-24-2297-01A 56 years, female, white, stage:Stage IIIC, dead, 1699 days 665.9
TCGA-24-2298-01A 55 years, female, white, stage:Stage IIIC, dead, 1620 days 661.3
TCGA-25-1318-01A 54 years, female, white, stage:Stage IIIC, dead, 1064 days 656.8
TCGA-61-2104-01A 53 years, female, white, stage:Stage IIC, alive, 2338 days 633.3
TCGA-13-1497-01A 47 years, female, white, stage:Stage IIIC, alive, 3871 days 630.8
TCGA-61-2102-01A 74 years, female, white, stage:Stage IIIC, dead, 197 days 473.9
TCGA-61-2113-01A 53 years, female, white, stage:Stage IIC, dead, 676 days 462.0
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OVARY SEROUS CYSTADENOCARCINOMA (VALIDATION) - Interactive survival scatter ploti

The Survival Scatter plot shows the clinical status (i.e. dead or alive) for all individuals in the patient cohort, based on the same data that underlies the corresponding Kaplan-Meier plots. Patients that are alive at last time for follow-up are shown in blue and patients who have died during the study are shown in red.

The x-axis shows the expression levels (FPKM) of the investigated gene in the tumor tissue at the time of diagnosis. The y-axis shows the follow-up time after diagnosis (years). Both axes are complimented with kernel density curves demonstrating the data density over the axes. The top density plot shows the expression levels (FPKM) distribution among dead (red) and alive patients (blue). The right density plot shows the data density of the survived years of dead patients with high and low expression levels respectively, stratified using the cutoff indicated by the vertical dashed line through the Survival Scatter plot. This cutoff is automatically defined based on the FPKM cutoff that minimizes the p-score. The cutoff can be changed by dragging the vertical line or by entering a cutoff value in the square labeled "Current cut-off".

Under the Survival Scatter plot the p-score landscape (black curve; left axis) is shown together with dead median separation (red curve; right axis). Dead median separation is the difference in median mRNA expression between patients who have died with high and low expression, respectively. It is calculated as follows: median FPKM expression of dead patients with high expression - median FPKM expression of dead patients with low expression. This is intended to aid the user in visually exploring custom cutoffs and the associated p-scores and dead median separation.

Individual patient data is displayed and can be filtered by clicking on one or more of the category buttons on the top of the page. Categories describing expression level and patient information include: high, low, alive, dead, female, male and tumor stages. The scale of the x-axis can be toggled between linear and log-scale by clicking on the "x log" button. Mouse-over function shows TCGA ID, patient information and mRNA expression (FPKM) for each patient.

& Survival analysisi

Kaplan-Meier plots summarize results from analysis of correlation between mRNA expression level and patient survival. Patients were divided based on level of expression into one of the two groups "low" (under cut off) or "high" (over cut off). X-axis shows time for survival (years) and y-axis shows the probability of survival, where 1.0 corresponds to 100 percent.

RPS4X is not prognostic in Ovary Serous Cystadenocarcinoma (validation)


Stage:
Survival analysis
Current cut offi

Current cut-off shows the cut-off (FPKM) currently selected. It may be changed manually. When the current cut-off is changed, the vertical dashed line indicating cut-off, the interactive survival scatter plot and the Kaplan-Meier curve will be automatically adjusted to show results accordingly.

:
Best expression cut offi

Based on the FPKM value of each gene, patients were classified into two groups and association between prognosis (survival) and gene expression (FPKM) was examined. The best expression cut-off refers the FPKM value that yields maximal difference with regard to survival between the two groups at the lowest log-rank P-value. Best expression cut-off was selected based on survival analysis .

When clicking on this number, the vertical dashed line indicating cut-off, the interactive survival plot, and the Kaplan-Meier curve will be adjusted to show results based on the best expression cut-off.

: 1037.7
Median expressioni

Median expression refers to the median FPKM value calculated based on the gene expression (FPKM) data from all patients in this dataset. When clicking on this number, the vertical dashed line indicating cut-off, the interactive survival plot, and the Kaplan-Meier curve will be adjusted to show results based on the median expression.

: N/A
Median follow up timei

Median follow up time refers to the median time (years) after diagnosis with this type of cancer, based on clinical data from all patients in this dataset.

: N/A
P scorei

Log-rank P value for Kaplan-Meier plot showing results from analysis of correlation between mRNA expression level and patient survival.

N/A
5-year survival highi

5-year survival for patients with higher expression than the expression cutoff.

For melanoma and glioma, 3-year survival is shown.

N/A
5-year survival lowi

5-year survival for patients with lower expression than the expression cutoff.

For melanoma and glioma, 3-year survival is shown.

N/A
TCGA RNA samplesi

RNA-seq data is reported as average FPKM (number Fragments Per Kilobase of exon per Million reads), generated by the The Cancer Genome Atlas (TCGA) .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. FPKM values of the individual samples are presented next to the box plot.

Average pTPM 1723.3
Number of samples 81
Samples
Sample Description pTPM
DO46523 52 years, female, NA, stage:IV, alive, 1873 days 6298.7
DO46384 55 years, female, NA, stage:III, dead, 614 days 5720.8
DO46338 59 years, female, NA, stage:III, dead, 596 days 4008.9
DO46328 52 years, female, NA, stage:III, dead, 972 days 3744.3
DO46561 52 years, female, NA, stage:III, dead, 195 days 3024.6
DO46390 65 years, female, NA, stage:III, dead, 374 days 2782.2
DO46370 54 years, female, NA, stage:III, dead, 1727 days 2685.5
DO46342 67 years, female, NA, stage:III, dead, 1398 days 2679.2
DO46597 60 years, female, NA, stage:III, dead, 393 days 2621.1
DO46606 73 years, female, NA, stage:III, alive, 804 days 2536.0
DO46533 46 years, female, NA, stage:III, alive, 3667 days 2521.9
DO46326 51 years, female, NA, stage:III, dead, 701 days 2457.0
DO46591 58 years, female, NA, stage:III, dead, 195 days 2422.8
DO46518 62 years, female, NA, stage:III, alive, 2960 days 2422.2
DO46404 55 years, female, NA, stage:III, dead, 690 days 2272.0
DO46560 45 years, female, NA, stage:IV, dead, 286 days 2138.0
DO46330 60 years, female, NA, stage:III, dead, 684 days 2077.2
DO46581 66 years, female, NA, stage:III, dead, 408 days 2069.6
DO46380 51 years, female, NA, stage:III, dead, 1423 days 2068.6
DO46366 65 years, female, NA, stage:III, dead, 2054 days 2016.8
DO46388 74 years, female, NA, stage:III, dead, 413 days 2013.7
DO46386 49 years, female, NA, stage:III, dead, 1162 days 1996.1
DO46586 55 years, female, NA, stage:III, dead, 1019 days 1937.0
DO46360 58 years, female, NA, stage:IV, dead, 1759 days 1930.2
DO46402 77 years, female, NA, stage:III, dead, 511 days 1898.5
DO46513 54 years, female, NA, stage:IV, dead, 1883 days 1892.5
DO46352 60 years, female, NA, stage:III, dead, 677 days 1880.2
DO46568 66 years, female, NA, stage:III, dead, 320 days 1873.3
DO46453 66 years, female, NA, stage:III, dead, 3294 days 1847.7
DO46538 57 years, female, NA, stage:III, dead, 1527 days 1845.9
DO46356 68 years, female, NA, stage:III, dead, 911 days 1827.6
DO46331 72 years, female, NA, stage:III, dead, 612 days 1805.1
DO46463 49 years, female, NA, stage:III, dead, 2451 days 1715.2
DO46392 48 years, female, NA, stage:III, dead, 628 days 1695.9
DO46611 52 years, female, NA, stage:III, dead, 734 days 1691.5
DO46325 54 years, female, NA, stage:III, dead, 477 days 1690.2
DO46458 67 years, female, NA, stage:IV, alive, 3787 days 1656.3
DO46346 54 years, female, NA, stage:III, dead, 1187 days 1646.2
DO46438 55 years, female, NA, stage:IV, alive, 2227 days 1611.6
DO46394 61 years, female, NA, stage:IV, dead, 1039 days 1599.1
DO46358 60 years, female, NA, stage:III, dead, 423 days 1558.5
DO46508 50 years, female, NA, stage:III, dead, 2101 days 1529.6
DO46344 46 years, female, NA, stage:III, dead, 642 days 1517.1
DO46364 45 years, female, NA, stage:III, dead, 806 days 1512.4
DO46333 58 years, female, NA, stage:III, dead, 359 days 1482.2
DO46408 56 years, female, NA, stage:III, dead, 489 days 1444.1
DO46432 56 years, female, NA, stage:III, alive, 2218 days 1443.2
DO46493 62 years, female, NA, stage:IV, alive, 839 days 1431.4
DO46576 75 years, female, NA, stage:III, alive, 133 days 1416.8
DO46400 70 years, female, NA, stage:III, dead, 719 days 1405.8
DO46376 58 years, female, NA, stage:III, dead, 1430 days 1282.0
DO46329 52 years, female, NA, stage:III, dead, 1699 days 1276.0
DO46443 59 years, female, NA, stage:III, dead, 2464 days 1230.1
DO46551 58 years, female, NA, stage:III, dead, 1055 days 1194.4
DO46378 59 years, female, NA, stage:III, alive, 843 days 1193.1
DO46354 73 years, female, NA, stage:III, dead, 843 days 1160.9
DO46588 74 years, female, NA, stage:III, dead, 438 days 1152.6
DO46412 64 years, female, NA, stage:III, dead, 597 days 1134.9
DO46602 74 years, female, NA, stage:III, dead, 205 days 1134.0
DO46372 39 years, female, NA, stage:III, dead, 1326 days 1128.0
DO46448 45 years, female, NA, stage:III, dead, 654 days 1125.4
DO46334 77 years, female, NA, stage:III, dead, 496 days 1121.6
DO46546 73 years, female, NA, stage:III, dead, 1889 days 1073.1
DO46396 64 years, female, NA, stage:III, dead, 583 days 1053.6
DO46428 59 years, female, NA, stage:IV, alive, 2644 days 1021.8
DO46468 67 years, female, NA, stage:III, alive, 2776 days 1018.2
DO46436 58 years, female, NA, stage:III, alive, 3193 days 962.1
DO46350 66 years, female, NA, stage:III, dead, 886 days 959.7
DO46368 57 years, female, NA, stage:III, dead, 2879 days 911.0
DO46382 62 years, female, NA, stage:IV, dead, 311 days 907.1
DO46398 66 years, female, NA, stage:III, alive, 437 days 887.8
DO46336 70 years, female, NA, stage:IV, dead, 664 days 869.7
DO46362 61 years, female, NA, stage:III, dead, 1639 days 862.5
DO46340 62 years, female, NA, stage:III, dead, 616 days 853.9
DO46332 56 years, female, NA, stage:III, dead, 689 days 761.0
DO46571 61 years, female, NA, stage:III, dead, 243 days 753.1
DO46528 56 years, female, NA, stage:III, alive, 6139 days 728.7
DO46566 78 years, female, NA, stage:III, dead, 673 days 707.1
DO46348 58 years, female, NA, stage:IV, dead, 287 days 687.5
DO46374 69 years, female, NA, stage:III, dead, 1409 days 549.0
DO46327 54 years, female, NA, stage:III, dead, 184 days 525.4
Show allShow less
OVARY SEROUS CYSTADENOCARCINOMA - Protein relative expression (CPTAC)
Number of samples 108
Samples
Sample ID Sample type nRPX
2b4ce90c-8036-4207-ac3e-54a76f_D2 Tumor 0.9
0cc794c3-5bf5-4621-b238-58a0f6_D2 Tumor 0.7
2563cb02-d58a-4286-8634-7502cd_D2 Tumor 0.6
91b287fd-eadb-442d-abcd-20b741_D2 Tumor 0.6
558333b0-ea23-4303-9e3c-4932b1_D2 Tumor 0.6
af95e2c6-25c4-4ab8-bf06-3e15ff_D2 Tumor 0.5
62f5840e-6cd7-4200-b651-645e53_D2 Tumor 0.5
a03d1103-b809-42c4-ad5c-5aff58_D2 Tumor 0.5
eb0a53df-7620-4024-8d2d-051142_D2 Tumor 0.5
41d0619e-b299-42e2-ac32-29e784_D2 Tumor 0.5
1de8d3d8-fc0e-4be0-8aa7-127c7b_D2 Tumor 0.5
2115808b-6a0d-49bc-a8d7-b83bde_D2 Tumor 0.5
3490835c-c004-45ed-91f3-7c206f_D2 Tumor 0.5
8d78194e-fbef-4819-a7b5-b73ae9_D2 Tumor 0.4
1b2ab076-c72f-4bbe-b9f9-657d24_D2 Tumor 0.4
2dc28da8-7ff1-4b9b-b5bd-17cc25_D2 Tumor 0.4
256ac9f5-1e19-44b4-92fb-fef3fc_D2 Tumor 0.4
76e77c6b-c80e-4391-bdbb-e1dcea_D2 Tumor 0.4
f6c215ea-5381-4521-bb61-be8e97_D2 Tumor 0.4
c17b0ff9-9057-4848-a0cc-abb25f_D2 Tumor 0.3
9b90eb78-2f50-4aeb-b010-d642f9_D2 Tumor 0.3
2224c03f-b7b1-4368-887e-2b4cdf_D2 Tumor 0.3
318d53c3-216b-4de1-a098-77d6dd_D2 Tumor 0.3
3946a96c-e0ae-442f-83b4-a9350e_D2 Tumor 0.3
7d953d1d-84b6-4ecd-b1d7-1ed865_D2 Tumor 0.3
a8853382-b726-4ce8-98d5-ca89df_D2 Tumor 0.3
d38f40fb-dd78-43b2-8b7b-4b6977_D2 Tumor 0.3
347e379b-77c0-4dd3-aa25-18c9d1_D2 Tumor 0.3
5c3971ee-87c7-4dff-b66e-f18892_D2 Tumor 0.2
7069e990-4a4e-4984-a66d-4d835a_D2 Tumor 0.2
9c8e78bf-b03e-4ba0-9909-5ff070_D2 Tumor 0.2
74a45e5a-a35a-4c60-a4b4-f3f5ea_D2 Tumor 0.2
28d0abdb-f682-4bd3-9425-a9c508_D2 Tumor 0.2
d109a3c0-350e-47f5-bda0-61899c_D2 Tumor 0.2
15524912-685a-47ce-a824-567848_D2 Tumor 0.2
52c064a7-78d9-4a1a-85b4-27c6d1_D2 Tumor 0.2
1772e913-f62e-446a-8cf3-720348_D2 Tumor 0.2
fe83e13f-9754-403b-8f74-d6caf8_D2 Tumor 0.2
5ea22f5e-307b-491d-801f-8b7fa6_D2 Tumor 0.2
e9d416e7-f661-400a-896e-388545_D2 Tumor 0.2
51a4ce2f-4166-4c6b-a7e0-942d0a_D2 Tumor 0.2
4ccb249a-6722-491e-97e9-e3b4e7_D2 Tumor 0.2
9e0d47e0-f633-468b-b82b-4d752d_D2 Tumor 0.1
8e17b45e-6a06-4e4e-913d-7b1edb_D2 Tumor 0.1
79b60f32-6cca-4cb6-9a1e-22a3ac_D2 Tumor 0.1
27f3ca2d-a86f-479d-8e7e-5307c7_D2 Tumor 0.1
80873a0c-1f40-4d51-bab1-3f2071_D2 Tumor 0.1
3a380577-c134-47ba-a1ce-988d7c_D2 Tumor 0.1
bd266bdd-12e4-42cb-9c49-911bfc_D2 Tumor 0.1
e7b656bf-3c34-4ba1-bdf3-c7eefe_D2 Tumor 0.1
927f0958-db5a-4bc5-92b7-2a3695_D2 Tumor 0.1
d4791079-c826-4fc7-9d9b-ee20ba_D2 Tumor 0.1
69d552be-7cb2-4bb4-b602-a27b3e_D2 Tumor 0.1
50997c44-1c8b-4d34-b535-4a6cc2_D2 Tumor 0.1
1c9145ad-1981-4871-aa7e-8b11de_D2 Tumor 0.0
6530147a-efe9-4df6-ac2f-03ece3_D2 Tumor 0.0
08296da7-70ea-44df-8646-09f2cc_D2 Tumor 0.0
10c2d629-0287-4511-ac25-f29031_D2 Tumor 0.0
627e6e36-3dca-4ee5-9755-6f3510_D2 Tumor 0.0
161317f3-1a39-438e-af45-cd2502_D2 Tumor 0.0
285fed94-1495-448e-879b-b55de9_D2 Tumor 0.0
42d860a3-8a0c-4c44-a09a-9ad8cf_D2 Tumor 0.0
6319b36b-533c-4e86-8e12-80552e_D3 Tumor -0.1
46c73531-f531-4ec3-97fe-b39d9d_D2 Tumor -0.1
2f901c90-617e-46da-9fac-d68369_D2 Tumor -0.1
e3ebe010-cd31-4b5d-8fcb-b7103b_D2 Tumor -0.1
3dcf8b3c-c0c5-4dfa-9543-5d30fb_D2 Tumor -0.1
eb3f3494-7057-4afe-b212-e6e9a3_D2 Tumor -0.1
0745488e-0bfb-4d1f-8228-dedf76_D1_D2 Normal -0.2
1db5574d-aca7-403c-8100-6e705f_D2 Normal -0.2
092af714-b97a-457c-b0e9-8c20e8_D2 Normal -0.2
ce1e5dfc-2ef1-4633-af93-5ea4d9_D2 Tumor -0.2
2433b136-fc7b-4cea-b958-bc6efb_D2 Tumor -0.2
8234f8ea-bdbd-45b0-bd0b-16f1e7_D2 Tumor -0.3
cfd76f9a-ce60-4ec7-8e6b-a8fc31_D3 Tumor -0.3
efc971f8-54c5-4531-a792-705ecf_D2 Tumor -0.3
a583d3ff-8165-43e9-b764-23b7ef_D1_D2 Normal -0.3
35a345a4-e954-4c81-ae3f-7797cd_D2 Tumor -0.3
3d3e1888-d67e-4c69-ba83-112d0f_D2 Tumor -0.3
1a10c200-3895-4648-b951-94f99f_D2 Tumor -0.3
685ec3c2-e67a-40d3-9eb3-aa01c9_D1_D2 Normal -0.4
994f9b8e-46cb-413f-8ec8-2c2fed_D2 Normal -0.4
61f76fe6-a1c6-41b8-bdc2-2f9209_D2 Normal -0.4
fbb41c94-aabd-49cc-90b2-882c3e_D2 Tumor -0.4
1abbcb28-f221-4cd4-8c01-37b9bb_D1_D2 Normal -0.4
340a3769-3031-41ae-bb08-a2f696_D2 Normal -0.4
2b73e01c-347a-4dae-a71d-752aeb_D2 Normal -0.4
49bd51fe-48a1-4828-b66e-b30c38_D2 Tumor -0.4
05387aad-2a1f-42c2-8d6f-950598_D3 Tumor -0.5
6e209757-a7f4-45af-b5f3-2ebc02_D2 Normal -0.5
8ed739dd-ae0f-4881-971a-db3cf4_D1_D2 Normal -0.5
9a7a86d3-bbf2-4d36-941d-c75c03_D1_D2 Tumor -0.5
3fbf076a-824b-4eac-b6dc-bf5e59_D2 Normal -0.5
1556af7e-c2ae-4fce-9aae-87c459_D1_D2 Normal -0.5
3e746bea-ed68-40e6-b348-6ddf08_D2 Normal -0.5
a65d8e76-640f-4341-a561-afbb57_D2 Normal -0.5
21efd60f-6a31-4b98-9477-16a905_D2 Normal -0.6
a3a26070-fb84-406a-8280-d555e6_D2 Normal -0.6
51c1c79e-5a8e-4b0a-bf92-1c0cab_D2 Tumor -0.6
b22659b9-e12c-4725-a7db-a833de_D1_D2 Normal -0.6
e23eb014-69c1-460a-b9d4-9786c8_D2 Normal -0.6
7c7ce2d7-6c8a-424e-8e6c-d14ad1_D2 Tumor -0.6
e6850782-fd2a-4c53-b682-1852fe_D2 Tumor -0.7
7edfd606-4bee-4529-9fec-1ca7f0_D2 Normal -0.7
2ed8beb2-bc63-4bad-b5fe-1916a0_D2 Tumor -0.7
31c15e30-21d4-4843-bd4a-9cd0d8_D2 Normal -0.8
b9c1f22e-61f7-45ed-b3b4-5094c7_D2 Normal -0.9
0c87932d-b6fd-4eb5-b86a-a34d07_D2 Tumor -0.9
Show allShow less
OVARIAN CANCER - Protein expressioni

A mouse-over function shows sample information and annotation data. Click on an image to view it in a full screen mode. Samples can be filtered based on level of antibody staining by selecting one or several of the following categories: high, medium, low and not detected. The assay and annotation is described here.

Note that samples used for immunohistochemistry by the Human Protein Atlas do not correspond to samples in the TCGA dataset.

 

Antibody stainingi

Antibody staining in the annotated cell types in the current human tissue is reported as not detected, low, medium, or high, based on conventional immunohistochemistry profiling in selected tissues. This score is based on the combination of the staining intensity and fraction of stained cells.

Each image is clickable and will lead to virtual microscopy that enables deeper exploration of all samples and also displays staining intensity scores, fraction scores and subcellular localization as well as patient and tissue information for each sample.


Antibody HPA000857
 Staining
  High
  Medium
  Low
  Not detected
 Intensity
  Strong
  Moderate
  Weak
  Negative
 Quantity
  >75%
  75%-25%
  <25%
  None
 Location
  Nuclear
  Cytoplasmic/membranous
  Cytoplasmic/membranous,nuclear
  None
Cystadenocarcinoma, serous, NOS
Cystadenocarcinoma, mucinous, NOS
Carcinoma, endometroid

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