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On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.
Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.
If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.
h
m
l
n
Cholangiocytes:
Not detected
Hepatocytes:
Not detected
RNA expressioni
A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.
The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.
Scroll down to view mRNA expression data in more detail.
Consensus:
122.8
nTPM
HPA:
20.5
nTPM
GTEx:
122.8
nTPM
FANTOM5:
247.1
Scaled Tags Per Million
LIVER - Antibody stainingi
Antibody staining in the annotated cell types in the current human tissue is reported as not detected, low, medium, or high, based on conventional immunohistochemistry profiling in selected tissues. This score is based on the combination of the staining intensity and fraction of stained cells.
Each image is clickable and will lead to virtual microscopy that enables deeper exploration of all samples and also displays staining intensity scores, fraction scores and subcellular localization as well as patient and tissue information for each sample.
Antibody HPA055334
Antibody HPA058450
Antibody CAB034012
Cholangiocytes
Not detected
Not detected
Low
Hepatocytes
Low
Not detected
Low
LIVER - HPA RNA-seqi
The RNA-seq details section shows detailed information about the individual samples used for the transcript profiling and results of the RNA-seq analysis.
Information about each individual sample is listed below, including gender, age, a tissue section image and estimated fractions of cell types. nTPM (normalized transcripts per million) values give a quantification of the gene abundance which is comparable between different genes and samples.
Average nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
20.5
Female, age 60
Liver sample 21 nTPM: 50.4
Male, age 54
Liver sample 23 nTPM: 1
Cell types%
Hepatocytes:
80
Fibroblasts:
15
Other cell types:
5
Male, age 74
Liver sample 24 nTPM: 5.4
Cell types%
Hepatocytes:
85
Fibroblasts:
5
Other cell types:
10
Female, age 62
Liver sample 350 nTPM: 6.4
Cell types%
Hepatocytes:
70
Fibroblasts:
10
Other cell types:
20
Male, age 78
Liver sample 351 nTPM: 77.3
Cell types%
Hepatocytes:
75
Fibroblasts:
5
Other cell types:
20
Male, age 53
Liver sample 352 nTPM: 9.9
Cell types%
Hepatocytes:
80
Fibroblasts:
5
Other cell types:
15
Male, age 77
Liver sample 353 nTPM: 12.4
Cell types%
Hepatocytes:
75
Fibroblasts:
5
Other cell types:
20
Female, age 72
Liver sample 359 nTPM: 34.2
Cell types%
Hepatocytes:
50
Fibroblasts:
10
Other cell types:
40
Male, age 70
Liver sample 367 nTPM: 3.2
Cell types%
Hepatocytes:
65
Fibroblasts:
10
Other cell types:
25
Female, age 23
Liver sample 396 nTPM: 4.8
Cell types%
Hepatocytes:
70
Fibroblasts:
5
Other cell types:
25
LIVER - GTEx RNA-seqi
RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.
Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
122.8
GTEx sample id
Sample description
nTPM
Liver Average nTPM: 122.8
Samples: 226
Max nTPM: 292.8
Min nTPM: 39.5
Std nTPM: 37.0
Median nTPM: 117.3
GTEX-14PJO-1726-SM-68719
60-69 years, male
292.8
GTEX-1MJIX-0726-SM-DPRYP
40-49 years, male
267.4
GTEX-1S82Y-1026-SM-EV7BJ
40-49 years, male
259.8
GTEX-P44G-1126-SM-3NM9D
30-39 years, male
232.0
GTEX-13O3O-1826-SM-5IFGW
60-69 years, female
227.7
GTEX-XBEC-1526-SM-4AT68
50-59 years, male
209.3
GTEX-15ER7-1826-SM-6LLI7
20-29 years, female
207.9
GTEX-1HB9E-0626-SM-AHZ4K
50-59 years, male
194.9
GTEX-ZYY3-0626-SM-5NQ6W
60-69 years, female
193.3
GTEX-11NUK-1226-SM-5P9GM
50-59 years, male
185.6
GTEX-13113-1326-SM-5GCOI
60-69 years, female
185.5
GTEX-1RQEC-1126-SM-EAZ5E
60-69 years, male
184.5
GTEX-12ZZZ-1326-SM-59HKW
60-69 years, male
182.5
GTEX-Y5LM-0426-SM-4VBRO
40-49 years, female
179.8
GTEX-145MO-2326-SM-5NQ9K
60-69 years, male
177.0
GTEX-YECK-1926-SM-4W21H
60-69 years, male
176.9
GTEX-1I1HK-1126-SM-AHZ2L
60-69 years, male
175.4
GTEX-1KD4Q-1526-SM-D4P3L
40-49 years, male
174.8
GTEX-1ICLY-1526-SM-C1YS4
50-59 years, male
174.1
GTEX-WZTO-0626-SM-4PQYY
40-49 years, male
173.2
GTEX-1LH75-0926-SM-EAZ5C
50-59 years, female
172.3
GTEX-RNOR-1426-SM-48FDJ
50-59 years, female
170.9
GTEX-13NZB-0626-SM-5IFH6
30-39 years, male
170.4
GTEX-145LU-1326-SM-5LU9N
50-59 years, male
170.2
GTEX-1B8SG-1326-SM-79ONT
50-59 years, male
169.8
GTEX-1A8FM-1226-SM-7IGMD
50-59 years, female
169.0
GTEX-1GF9W-0826-SM-7MKHI
60-69 years, male
168.9
GTEX-1AX9I-1626-SM-72D5D
60-69 years, male
167.3
GTEX-17HGU-1826-SM-7IGQM
50-59 years, male
166.7
GTEX-ZAB4-0826-SM-5LU9D
40-49 years, male
164.8
GTEX-1I1GR-1526-SM-CNNQE
60-69 years, male
163.4
GTEX-XXEK-1126-SM-4BRUX
50-59 years, male
162.1
GTEX-131XH-0626-SM-5LZWH
50-59 years, male
161.3
GTEX-18465-1626-SM-7LG6N
50-59 years, male
160.6
GTEX-WK11-1326-SM-4OOSI
50-59 years, male
160.5
GTEX-11GSP-0626-SM-5986T
60-69 years, female
159.6
GTEX-11TT1-1726-SM-5EQLJ
20-29 years, male
159.5
GTEX-O5YT-0826-SM-3TW8N
20-29 years, male
156.5
GTEX-132NY-0926-SM-5P9G3
60-69 years, male
155.4
GTEX-144GM-1326-SM-5LU5E
20-29 years, male
153.8
GTEX-11NV4-1326-SM-5HL6V
60-69 years, male
153.7
GTEX-1K9T9-0726-SM-CXZJZ
50-59 years, female
153.4
GTEX-1KAFJ-0726-SM-CXZKF
50-59 years, male
152.8
GTEX-1B996-1426-SM-7EPIA
60-69 years, male
152.1
GTEX-1QP66-0226-SM-DPRXS
50-59 years, male
145.8
GTEX-15SHU-1826-SM-7KUKS
40-49 years, female
145.7
GTEX-YEC4-0826-SM-5P9FV
40-49 years, male
144.0
GTEX-X3Y1-2726-SM-4PQZH
40-49 years, male
143.6
GTEX-15RJE-1126-SM-6LPI5
40-49 years, male
142.8
GTEX-X4EO-1126-SM-4QARQ
60-69 years, female
142.6
GTEX-1GF9V-1226-SM-7MKGY
60-69 years, male
142.4
GTEX-1CAMQ-1426-SM-7MKFL
40-49 years, male
142.3
GTEX-1EKGG-1226-SM-7IGNO
60-69 years, male
142.2
GTEX-ZVT4-0626-SM-5E45T
50-59 years, female
141.1
GTEX-1JMLX-1326-SM-CXZJO
50-59 years, male
141.0
GTEX-SJXC-1226-SM-4DM78
60-69 years, male
140.1
GTEX-13O1R-2026-SM-5KM3N
60-69 years, male
139.9
GTEX-X261-1726-SM-4PQYT
50-59 years, male
139.7
GTEX-1S5VW-1826-SM-EAZ53
60-69 years, male
139.4
GTEX-144GL-1426-SM-79OMA
50-59 years, male
139.0
GTEX-ZTPG-1426-SM-51MT3
20-29 years, female
138.7
GTEX-11DXZ-0126-SM-5EGGY
50-59 years, male
137.8
GTEX-1269C-0626-SM-5FQSS
60-69 years, female
137.8
GTEX-18A6Q-2026-SM-718AQ
60-69 years, male
137.2
GTEX-1497J-0726-SM-5Q5D1
60-69 years, male
136.9
GTEX-Q2AG-1126-SM-48U1P
40-49 years, female
135.4
GTEX-1PBJJ-0626-SM-DPRYO
30-39 years, male
135.1
GTEX-1C6VQ-1626-SM-79OO1
50-59 years, male
134.9
GTEX-RN64-1826-SM-48FDV
50-59 years, male
134.4
GTEX-13PVQ-1526-SM-5IFEQ
50-59 years, male
134.1
GTEX-1PIIG-1326-SM-EXOIR
30-39 years, male
133.7
GTEX-1HBPI-1026-SM-AHZ4N
50-59 years, male
133.6
GTEX-11TUW-1726-SM-5BC5C
60-69 years, male
133.4
GTEX-1JJ6O-0826-SM-CXZJL
60-69 years, male
133.4
GTEX-1A32A-0826-SM-72D5C
50-59 years, female
133.1
GTEX-YFC4-1526-SM-5IFJS
40-49 years, female
132.7
GTEX-WQUQ-1926-SM-4OOSA
60-69 years, male
132.5
GTEX-12KS4-1326-SM-5LUB3
30-39 years, male
131.2
GTEX-1E2YA-1226-SM-7MGY3
50-59 years, male
131.2
GTEX-1J8EW-1626-SM-C1YQ8
60-69 years, female
130.2
GTEX-X4EP-1026-SM-4QAS5
60-69 years, female
130.0
GTEX-15RJ7-2026-SM-6LPJ4
40-49 years, male
129.4
GTEX-11ZUS-2526-SM-59872
30-39 years, male
128.5
GTEX-1HBPH-2626-SM-A96TV
40-49 years, female
127.5
GTEX-13NYB-1026-SM-5IFH3
40-49 years, male
127.1
GTEX-15SZO-1226-SM-6LPIP
50-59 years, male
126.9
GTEX-1EWIQ-0726-SM-7MKFW
70-79 years, female
126.6
GTEX-12WSD-1426-SM-5GCN9
60-69 years, female
126.2
GTEX-17MF6-1126-SM-7DUFS
40-49 years, male
126.2
GTEX-13N2G-0926-SM-5IFGJ
60-69 years, male
126.0
GTEX-11OF3-0726-SM-5BC4Z
60-69 years, male
124.9
GTEX-1KD5A-1226-SM-CXZK7
50-59 years, male
124.7
GTEX-17EVP-1026-SM-7IGOZ
40-49 years, male
123.7
GTEX-1CB4J-0726-SM-7IGN8
60-69 years, male
123.7
GTEX-18D9B-1526-SM-7KFRK
60-69 years, male
123.3
GTEX-OOBJ-0826-SM-3NB2K
60-69 years, male
123.3
GTEX-Y111-0726-SM-EYYVM
50-59 years, male
123.1
GTEX-13PVR-0126-SM-5S2PY
60-69 years, female
122.9
GTEX-13112-1426-SM-5EGH8
50-59 years, male
122.6
GTEX-1NV8Z-1626-SM-DPRYT
60-69 years, male
122.2
GTEX-1B8L1-0726-SM-7P8RT
60-69 years, male
121.4
GTEX-11ZVC-0726-SM-5FQT9
50-59 years, female
121.2
GTEX-WVLH-2126-SM-EYYWD
50-59 years, male
120.8
GTEX-1HCU7-1726-SM-B2LX9
50-59 years, male
120.6
GTEX-13N11-0926-SM-5IJG2
50-59 years, female
120.3
GTEX-RWSA-1426-SM-47JXA
40-49 years, male
120.3
GTEX-T6MN-1226-SM-3NMA5
50-59 years, male
120.3
GTEX-QDVN-0826-SM-48TZ2
50-59 years, male
120.2
GTEX-1EH9U-1126-SM-7IGLU
60-69 years, male
118.5
GTEX-12696-0826-SM-5EGGE
60-69 years, male
118.1
GTEX-139TU-0826-SM-5IJFG
60-69 years, male
117.8
GTEX-O5YV-0726-SM-EV798
60-69 years, female
117.7
GTEX-1B933-1226-SM-731DW
50-59 years, female
117.4
GTEX-131YS-1626-SM-5HL6C
60-69 years, female
117.2
GTEX-17HII-1026-SM-7IGLY
50-59 years, male
117.1
GTEX-147F4-1426-SM-5LUA8
50-59 years, male
117.0
GTEX-13X6J-1826-SM-5TDCT
50-59 years, male
116.3
GTEX-14A5I-1726-SM-5QGQ5
50-59 years, female
116.3
GTEX-P78B-1326-SM-3P611
40-49 years, female
116.2
GTEX-QESD-2026-SM-447BI
20-29 years, male
115.4
GTEX-OIZF-0826-SM-3MJGO
60-69 years, male
115.4
GTEX-1F75A-1626-SM-9JGGT
50-59 years, male
115.2
GTEX-1QP6S-1326-SM-DPRZ8
40-49 years, male
114.9
GTEX-S32W-1926-SM-4AD63
50-59 years, female
114.7
GTEX-139TS-1426-SM-5IFJD
60-69 years, male
114.6
GTEX-1EN7A-2026-SM-7MGY4
40-49 years, male
114.6
GTEX-17F96-1226-SM-79OK2
70-79 years, male
113.2
GTEX-1399R-1226-SM-5P9GF
30-39 years, male
112.8
GTEX-147JS-1126-SM-5RQIW
60-69 years, male
112.0
GTEX-REY6-1226-SM-48FDR
60-69 years, male
111.8
GTEX-1212Z-0226-SM-59HLF
60-69 years, male
111.6
GTEX-1A8G7-1126-SM-731ED
60-69 years, male
111.6
GTEX-13QJC-0726-SM-5RQJK
60-69 years, female
111.5
GTEX-15DYW-1326-SM-6LPIV
60-69 years, female
111.2
GTEX-1GN73-1126-SM-9OSW5
60-69 years, male
110.9
GTEX-1GF9X-0426-SM-7MKHN
40-49 years, female
110.2
GTEX-X4XY-1626-SM-46MVN
60-69 years, male
110.2
GTEX-1IKJJ-1526-SM-C1YSC
60-69 years, male
110.1
GTEX-1KWVE-0326-SM-EV7AF
30-39 years, male
110.1
GTEX-1LGRB-0626-SM-CNNQH
50-59 years, female
109.2
GTEX-148VI-0626-SM-5TDDH
60-69 years, female
109.1
GTEX-14BIL-1326-SM-79OMR
50-59 years, male
108.8
GTEX-Z9EW-0426-SM-5CVM9
40-49 years, male
108.4
GTEX-13FTW-1126-SM-5J2NV
40-49 years, male
108.0
GTEX-146FH-1526-SM-5NQBU
50-59 years, female
107.1
GTEX-S4Z8-0526-SM-4AD4T
60-69 years, male
107.1
GTEX-1GN1U-0926-SM-9WPPY
50-59 years, female
107.1
GTEX-131XE-0326-SM-5LZVO
50-59 years, male
106.8
GTEX-WY7C-0726-SM-4ONCB
50-59 years, male
106.7
GTEX-ZPU1-0826-SM-57WG2
40-49 years, male
106.7
GTEX-WYVS-1926-SM-4PQZ2
40-49 years, female
106.1
GTEX-ZF2S-3026-SM-4WWCH
50-59 years, female
106.0
GTEX-14753-1626-SM-5NQ9L
60-69 years, male
104.7
GTEX-1R9JW-0826-SM-DPRZJ
30-39 years, female
104.3
GTEX-12WSG-0626-SM-5FQTQ
50-59 years, female
104.2
GTEX-14XAO-0226-SM-68728
60-69 years, female
104.2
GTEX-ZZPU-0426-SM-5GZYH
50-59 years, female
104.2
GTEX-11DXY-0526-SM-5EGGQ
60-69 years, male
102.9
GTEX-13VXU-0926-SM-5IFFH
50-59 years, male
102.7
GTEX-18A66-2026-SM-7189C
60-69 years, male
102.1
GTEX-14JG1-1626-SM-664NH
40-49 years, male
102.0
GTEX-1IKK5-0326-SM-C1YPY
60-69 years, male
101.2
GTEX-14C38-1526-SM-5RQJ7
50-59 years, male
101.1
GTEX-1AMFI-0826-SM-731DV
50-59 years, female
100.7
GTEX-1CB4F-1726-SM-7MGXH
60-69 years, male
100.4
GTEX-13OW6-2626-SM-5IFF2
50-59 years, male
100.2
GTEX-UTHO-2426-SM-4JBHD
60-69 years, male
99.8
GTEX-ZF29-2026-SM-DNZYW
60-69 years, female
99.2
GTEX-11EQ9-0526-SM-5A5JZ
30-39 years, male
99.1
GTEX-YB5E-0326-SM-5IFHU
40-49 years, male
98.5
GTEX-QEL4-1226-SM-447A4
50-59 years, male
97.8
GTEX-RU72-1426-SM-46MUF
50-59 years, female
97.5
GTEX-1GN2E-0926-SM-9WPOH
60-69 years, male
96.8
GTEX-1KANB-2226-SM-DHXJW
50-59 years, male
96.6
GTEX-U8XE-1526-SM-4E3HT
30-39 years, male
95.4
GTEX-ZEX8-0826-SM-4WKHK
50-59 years, male
95.1
GTEX-RM2N-1926-SM-48FCU
50-59 years, male
94.4
GTEX-1B932-1426-SM-793AN
40-49 years, female
94.0
GTEX-13SLX-1226-SM-5S2Q6
50-59 years, female
93.9
GTEX-TKQ2-1726-SM-4DXUP
50-59 years, male
93.8
GTEX-11ZTS-1426-SM-5EQMM
60-69 years, female
92.7
GTEX-12WSM-0726-SM-5GCOW
60-69 years, male
92.5
GTEX-14DAQ-1726-SM-5S2R2
60-69 years, female
92.1
GTEX-11WQC-0726-SM-5EQMR
60-69 years, male
91.6
GTEX-1AX8Z-1026-SM-7189R
60-69 years, male
91.1
GTEX-139YR-0226-SM-5IFEM
50-59 years, male
90.1
GTEX-132AR-0426-SM-5IFH8
50-59 years, female
89.1
GTEX-13FTZ-0726-SM-5IFFY
60-69 years, male
88.9
GTEX-147GR-1326-SM-7IGLB
60-69 years, male
87.6
GTEX-1QCLZ-1226-SM-EAZ49
60-69 years, female
87.2
GTEX-1HT8W-0826-SM-C1YRJ
30-39 years, male
85.9
GTEX-13NZ9-1326-SM-5MR3V
50-59 years, male
85.1
GTEX-12WSL-0226-SM-5CVMJ
50-59 years, male
84.8
GTEX-ZAB5-0426-SM-5CVMI
50-59 years, male
84.8
GTEX-1JJEA-1526-SM-CNNPK
60-69 years, male
84.0
GTEX-13FLV-0326-SM-5N9DJ
50-59 years, male
83.9
GTEX-18A7A-1526-SM-72D69
50-59 years, female
83.7
GTEX-PX3G-0826-SM-48TZS
20-29 years, female
83.5
GTEX-12WSI-0226-SM-5GCNA
50-59 years, male
82.7
GTEX-Q734-0326-SM-48U15
40-49 years, female
82.7
GTEX-QV44-0326-SM-C1YQX
50-59 years, male
82.5
GTEX-1GZ4I-1526-SM-9OSW9
50-59 years, male
82.1
GTEX-WFON-1726-SM-4LVMQ
40-49 years, male
81.6
GTEX-1H11D-0826-SM-9OSWB
40-49 years, male
81.0
GTEX-ZYT6-0626-SM-5E45V
30-39 years, male
80.9
GTEX-ZVT3-1626-SM-5GU66
60-69 years, female
80.0
GTEX-1QPFJ-1126-SM-E9U5V
30-39 years, female
79.8
GTEX-1HCVE-1526-SM-B2LWW
50-59 years, male
78.9
GTEX-14PHX-0526-SM-664NW
50-59 years, male
78.0
GTEX-Y5V5-0926-SM-4VBPZ
60-69 years, female
77.8
GTEX-QEG4-1826-SM-CKZN9
30-39 years, male
77.5
GTEX-R53T-0326-SM-48FEC
50-59 years, female
76.3
GTEX-17HHE-0126-SM-79398
50-59 years, male
74.7
GTEX-ZVP2-0626-SM-51MSO
50-59 years, male
74.0
GTEX-UPK5-1426-SM-4JBHH
40-49 years, male
73.2
GTEX-14AS3-0126-SM-5Q5F4
40-49 years, female
72.8
GTEX-145MF-0826-SM-5QGQA
50-59 years, male
72.1
GTEX-S33H-1626-SM-4AD68
30-39 years, male
72.1
GTEX-1399T-0826-SM-5IFES
60-69 years, male
70.6
GTEX-VUSG-0126-SM-4KL1X
50-59 years, male
70.1
GTEX-14E1K-0326-SM-5S2PE
50-59 years, male
68.9
GTEX-1BAJH-1526-SM-7RHGI
70-79 years, male
68.8
GTEX-14E7W-1526-SM-6871X
70-79 years, male
67.7
GTEX-1ICG6-1026-SM-B2LY6
70-79 years, female
63.8
GTEX-RTLS-1326-SM-46MUN
60-69 years, female
62.7
GTEX-U3ZN-0226-SM-3DB8D
30-39 years, female
39.5
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LIVER - FANTOM5 CAGEi
RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.
Max subtype Scaled Tags Per Millioni
Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.
The Human Protein Atlas project is funded
