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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:202.2 nTPM
HPA Brain:147.0 nTPM
GTEx:202.2 nTPM
FANTOM5:67.7 Scaled Tags Per Million
Pig:23.9 nTPM
Mouse:112.8 nTPM
Allen mouse:9.1 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

147.0
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 104.5
2586 Male, age 75, left hemisphere 136.5
2411 Female, age 72, unknown 130.2
2828 Female, age 72, unknown 114.5
1827 Male, age 72, unknown 109.1
1870 Female, age 42, unknown 103.3
1833 Male, age 53, unknown 99.0
1830 Male, age 51, unknown 96.5
2219 Male, age 76, both hemispheres 90.0
2666 Male, age 74, left hemisphere 83.0
2019 Male, age 18, unknown 82.5
Dorsal raphe nucleus
nTPM: 141.2
2298 Female, age 72, unknown 194.4
2047 Male, age 72, unknown 150.8
2016 Female, age 72, unknown 123.8
1828 Male, age 53, unknown 122.5
2750 Male, age 76, both hemispheres 114.7
Inferior colliculus
nTPM: 119.9
2097 Female, age 72, unknown 140.3
1848 Female, age 42, unknown 119.0
1890 Male, age 53, unknown 115.8
2849 Male, age 72, unknown 104.7
Median raphe nucleus
nTPM: 140.7
2220 Male, age 76, midline 140.7
Periaquaductal grey, anterior
nTPM: 147.0
1947 Male, age 18, unknown 164.7
2502 Female, age 75, unknown 142.7
1795 Male, age 51, unknown 133.5
Periaquaductal grey, dorsal
nTPM: 119.8
1840 Male, age 53, unknown 141.0
2850 Male, age 76, both hemispheres 121.3
2464 Female, age 72, unknown 120.0
1831 Male, age 72, unknown 97.0
Periaquaductal grey, lateral
nTPM: 114.3
2140 Male, age 76, both hemispheres 129.1
2053 Male, age 18, unknown 108.9
2272 Male, age 74, both hemispheres 105.0
Pretectal area
nTPM: 106.6
2224 Female, age 72, unknown 141.5
2273 Male, age 74, both hemispheres 122.0
2825 Male, age 18, unknown 121.2
2316 Male, age 76, right hemisphere 116.3
1817 Female, age 42, unknown 106.6
2007 Male, age 72, unknown 102.6
2667 Female, age 75, unknown 101.5
1944 Female, age 72, unknown 96.1
1816 Male, age 51, unknown 93.6
1815 Male, age 53, unknown 92.6
2407 Male, age 75, both hemispheres 78.9
Red nucleus
nTPM: 101.3
2503 Female, age 72, unknown 125.0
2227 Male, age 72, unknown 115.3
1821 Female, age 72, unknown 114.7
2725 Female, age 75, unknown 114.6
2769 Male, age 72, unknown 112.0
1954 Female, age 42, unknown 107.3
1904 Male, age 53, unknown 94.3
2588 Male, age 74, left hemisphere 91.0
2785 Male, age 18, unknown 86.9
2823 Male, age 76, right hemisphere 86.5
1865 Male, age 51, unknown 85.5
2584 Male, age 75, left hemisphere 82.0
Substantia nigra
nTPM: 118.1
1916 Female, age 42, unknown 168.4
1851 Male, age 51, unknown 145.8
2241 Male, age 72, unknown 125.3
2699 Male, age 18, unknown 121.7
1941 Male, age 53, unknown 115.4
1889 Female, age 72, unknown 113.3
2665 Male, age 74, both hemispheres 101.6
2590 Female, age 75, unknown 101.5
2409 Female, age 72, unknown 96.1
2583 Male, age 75, right hemisphere 92.2
Superior colliculus
nTPM: 105.2
1796 Male, age 53, unknown 131.9
1839 Male, age 51, unknown 119.1
2261 Male, age 18, unknown 116.0
2668 Female, age 75, unknown 111.4
2087 Female, age 72, unknown 102.6
2664 Male, age 75, both hemispheres 98.6
2587 Male, age 74, left hemisphere 97.8
1995 Male, age 72, unknown 93.6
1895 Male, age 76, right hemisphere 92.2
1913 Female, age 42, unknown 89.0
Ventral tegmental area
nTPM: 134.8
1915 Female, age 42, unknown 155.6
1942 Male, age 51, unknown 144.9
2410 Female, age 72, unknown 132.8
2021 Male, age 53, unknown 132.1
2218 Male, age 76, both hemispheres 121.8
2223 Female, age 72, unknown 121.5

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

202.2
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 202.2
Samples: 139

Max nTPM: 466.6
Min nTPM: 84.3
Std nTPM: 67.7
Median nTPM: 194.1
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 466.6
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 447.9
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 430.2
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 398.7
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 369.8
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 362.4
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 340.1
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 331.5
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 321.9
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 321.4
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 291.7
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 275.1
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 273.2
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 271.7
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 266.5
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 265.7
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 264.3
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 263.8
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 255.4
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 253.0
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 252.7
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 252.1
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 251.7
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 251.4
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 251.3
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 251.1
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 249.9
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 249.4
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 246.1
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 243.7
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 243.4
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 240.5
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 238.8
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 236.1
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 233.6
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 232.4
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 231.9
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 230.9
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 230.9
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 229.3
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 227.5
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 226.8
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 218.8
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 217.4
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 215.5
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 213.0
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 212.2
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 212.0
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 210.8
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 210.4
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 209.9
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 209.9
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 209.7
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 209.7
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 209.6
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 209.1
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 209.0
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 208.8
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 208.2
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 207.6
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 207.1
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 202.9
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 201.3
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 199.1
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 197.3
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 197.2
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 196.5
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 195.7
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 194.6
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 194.1
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 192.8
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 191.9
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 191.8
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 191.7
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 191.4
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 190.2
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 189.3
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 188.6
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 187.4
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 187.4
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 179.9
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 178.7
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 178.0
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 177.2
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 175.5
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 173.4
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 171.9
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 171.4
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 169.9
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 169.2
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 168.8
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 165.8
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 165.6
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 163.8
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 163.6
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 162.8
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 162.6
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 162.1
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 161.7
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 161.3
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 160.9
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 160.8
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 159.7
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 158.7
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 158.6
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 157.3
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 153.9
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 153.4
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 152.0
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 151.8
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 151.8
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 151.1
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 148.0
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 146.2
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 145.7
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 145.7
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 142.8
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 142.4
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 140.1
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 139.5
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 138.4
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 137.0
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 136.0
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 135.8
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 134.9
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 134.3
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 133.9
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 130.2
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 119.6
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 119.2
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 115.9
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 114.5
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 113.6
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 103.8
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 100.7
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 98.9
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 98.4
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 94.3
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 84.3
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

67.7
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 67.7
FF:10158-103A5 76 years, female 67.7

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

23.9
Pig sample Sample description nTPM
Substantia nigra
nTPM: 23.4
Samples: 4

Max nTPM: 30.8
Min nTPM: 17.9
Sample A Female 24.1
Sample B Female 30.8
Sample C Male 20.8
Sample D Male 17.9
Midbrain
nTPM: 16.0
Samples: 4

Max nTPM: 19.1
Min nTPM: 8.2
Sample A Female 17.5
Sample B Female 19.1
Sample C Male 19.0
Sample D Male 8.2
Periaqueductal gray
nTPM: 9.8
Samples: 3

Max nTPM: 11.7
Min nTPM: 6.4
Sample B Female 11.7
Sample C Male 11.4
Sample D Male 6.4
Superior colliculi
nTPM: 23.9
Samples: 4

Max nTPM: 31.3
Min nTPM: 15.1
Sample A Female 22.3
Sample B Female 26.9
Sample C Male 31.3
Sample D Male 15.1

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

112.8
Mouse sample Sample description nTPM
Midbrain
nTPM: 112.9
Samples: 4

Max nTPM: 148.6
Min nTPM: 85.4
Sample A Male 148.6
Sample B Male 101.0
Sample C Female 85.4
Sample D Female 116.4

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

9.1
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 9.1
641541 Antisense, RP_040914_01_F12, Mouse strain C57BL/6J (56 days, male) 9.1

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