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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:273.1 nTPM
HPA Brain:394.8 nTPM
GTEx:273.1 nTPM
FANTOM5:242.9 Scaled Tags Per Million
Pig:557.8 nTPM
Mouse:432.4 nTPM
Allen mouse:21.4 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

394.8
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 353.4
1827 Male, age 72, unknown 410.5
2666 Male, age 74, left hemisphere 397.2
2411 Female, age 72, unknown 369.1
1870 Female, age 42, unknown 355.3
2828 Female, age 72, unknown 348.9
2586 Male, age 75, left hemisphere 346.9
2019 Male, age 18, unknown 336.8
2219 Male, age 76, both hemispheres 335.9
1833 Male, age 53, unknown 332.1
1830 Male, age 51, unknown 301.3
Dorsal raphe nucleus
nTPM: 334.8
2298 Female, age 72, unknown 367.7
2047 Male, age 72, unknown 357.3
2750 Male, age 76, both hemispheres 352.0
1828 Male, age 53, unknown 323.4
2016 Female, age 72, unknown 273.4
Inferior colliculus
nTPM: 335.4
2849 Male, age 72, unknown 366.2
2097 Female, age 72, unknown 333.5
1848 Female, age 42, unknown 330.2
1890 Male, age 53, unknown 311.7
Median raphe nucleus
nTPM: 394.8
2220 Male, age 76, midline 394.8
Periaquaductal grey, anterior
nTPM: 339.8
1947 Male, age 18, unknown 367.7
1795 Male, age 51, unknown 353.4
2502 Female, age 75, unknown 298.4
Periaquaductal grey, dorsal
nTPM: 320.7
1840 Male, age 53, unknown 344.8
2850 Male, age 76, both hemispheres 333.3
1831 Male, age 72, unknown 329.1
2464 Female, age 72, unknown 275.8
Periaquaductal grey, lateral
nTPM: 300.0
2053 Male, age 18, unknown 320.6
2272 Male, age 74, both hemispheres 300.6
2140 Male, age 76, both hemispheres 278.9
Pretectal area
nTPM: 379.9
1817 Female, age 42, unknown 458.4
1816 Male, age 51, unknown 450.4
2007 Male, age 72, unknown 438.3
1944 Female, age 72, unknown 425.5
1815 Male, age 53, unknown 401.4
2667 Female, age 75, unknown 389.0
2224 Female, age 72, unknown 356.1
2407 Male, age 75, both hemispheres 355.3
2825 Male, age 18, unknown 331.9
2273 Male, age 74, both hemispheres 313.1
2316 Male, age 76, right hemisphere 259.5
Red nucleus
nTPM: 316.6
1821 Female, age 72, unknown 356.4
2584 Male, age 75, left hemisphere 346.9
2785 Male, age 18, unknown 342.9
2588 Male, age 74, left hemisphere 342.6
2725 Female, age 75, unknown 333.2
1865 Male, age 51, unknown 314.4
2503 Female, age 72, unknown 302.7
1954 Female, age 42, unknown 296.0
2769 Male, age 72, unknown 295.9
1904 Male, age 53, unknown 294.5
2823 Male, age 76, right hemisphere 293.2
2227 Male, age 72, unknown 281.0
Substantia nigra
nTPM: 346.8
1916 Female, age 42, unknown 413.0
1889 Female, age 72, unknown 407.3
1941 Male, age 53, unknown 406.0
1851 Male, age 51, unknown 361.6
2583 Male, age 75, right hemisphere 350.3
2665 Male, age 74, both hemispheres 325.6
2590 Female, age 75, unknown 316.9
2699 Male, age 18, unknown 310.8
2241 Male, age 72, unknown 297.4
2409 Female, age 72, unknown 279.3
Superior colliculus
nTPM: 342.5
2668 Female, age 75, unknown 383.7
1796 Male, age 53, unknown 365.7
2087 Female, age 72, unknown 357.5
2261 Male, age 18, unknown 353.1
2587 Male, age 74, left hemisphere 346.5
1895 Male, age 76, right hemisphere 339.7
2664 Male, age 75, both hemispheres 334.2
1839 Male, age 51, unknown 330.4
1913 Female, age 42, unknown 327.2
1995 Male, age 72, unknown 287.2
Ventral tegmental area
nTPM: 351.9
2218 Male, age 76, both hemispheres 387.1
1915 Female, age 42, unknown 367.8
2410 Female, age 72, unknown 367.2
2223 Female, age 72, unknown 365.5
1942 Male, age 51, unknown 322.2
2021 Male, age 53, unknown 301.6

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

273.1
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 273.1
Samples: 139

Max nTPM: 595.1
Min nTPM: 172.4
Std nTPM: 63.6
Median nTPM: 264.3
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 595.1
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 481.7
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 441.6
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 417.5
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 406.9
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 380.0
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 377.9
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 371.3
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 371.0
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 368.9
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 368.6
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 368.2
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 368.0
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 365.7
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 355.5
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 347.9
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 345.9
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 339.6
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 334.3
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 334.0
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 333.3
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 329.0
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 326.7
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 325.4
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 323.9
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 322.0
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 319.4
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 311.0
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 310.4
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 308.9
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 308.8
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 308.4
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 307.4
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 306.2
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 305.2
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 304.6
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 304.5
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 301.8
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 301.6
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 299.1
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 298.8
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 296.6
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 296.2
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 295.8
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 295.3
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 294.1
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 292.7
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 292.1
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 291.1
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 289.8
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 289.8
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 289.4
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 288.8
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 288.5
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 285.9
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 284.0
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 282.4
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 278.9
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 277.3
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 276.4
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 275.9
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 272.0
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 271.6
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 270.6
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 269.8
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 269.3
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 268.9
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 267.7
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 267.6
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 264.3
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 263.6
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 259.2
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 257.3
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 256.8
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 253.7
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 253.4
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 252.2
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 246.8
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 246.7
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 246.2
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 244.1
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 244.0
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 241.5
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 241.1
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 238.8
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 238.6
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 238.1
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 237.8
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 237.8
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 237.3
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 236.4
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 236.4
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 234.5
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 234.5
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 234.2
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 234.1
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 233.9
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 233.1
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 232.8
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 232.5
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 231.4
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 230.6
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 227.7
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 226.8
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 225.1
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 225.1
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 224.5
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 224.5
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 223.9
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 223.4
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 222.3
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 221.0
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 219.9
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 218.7
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 217.9
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 217.6
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 217.2
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 215.5
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 215.4
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 209.9
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 209.7
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 209.7
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 209.3
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 208.4
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 207.4
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 207.1
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 207.1
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 205.1
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 200.5
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 199.8
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 197.3
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 196.1
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 195.8
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 194.1
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 188.2
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 187.6
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 187.2
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 178.3
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 172.4
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

242.9
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 242.9
FF:10158-103A5 76 years, female 242.9

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

557.8
Pig sample Sample description nTPM
Substantia nigra
nTPM: 442.0
Samples: 4

Max nTPM: 538.1
Min nTPM: 326.4
Sample A Female 538.1
Sample B Female 326.4
Sample C Male 525.1
Sample D Male 378.4
Midbrain
nTPM: 557.8
Samples: 4

Max nTPM: 718.4
Min nTPM: 368.2
Sample A Female 597.8
Sample B Female 368.2
Sample C Male 718.4
Sample D Male 546.9
Periaqueductal gray
nTPM: 386.4
Samples: 3

Max nTPM: 452.0
Min nTPM: 347.4
Sample B Female 347.4
Sample C Male 452.0
Sample D Male 359.9
Superior colliculi
nTPM: 530.6
Samples: 4

Max nTPM: 644.0
Min nTPM: 350.0
Sample A Female 564.8
Sample B Female 350.0
Sample C Male 644.0
Sample D Male 563.5

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

432.4
Mouse sample Sample description nTPM
Midbrain
nTPM: 432.4
Samples: 4

Max nTPM: 442.2
Min nTPM: 418.7
Sample A Male 418.7
Sample B Male 442.2
Sample C Female 439.4
Sample D Female 429.3

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

21.4
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 21.4
74357589 Antisense, RP_060117_01_A05, Mouse strain C57BL/6J (56 days, male) 21.4

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