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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:465.0 nTPM
HPA Brain:137.8 nTPM
GTEx:465.0 nTPM
FANTOM5:75.1 Scaled Tags Per Million
Pig:172.6 nTPM
Mouse:115.4 nTPM
Allen mouse:0.1 Expression energy

MIDBRAIN - Annotated protein expression
Pending normal tissue analysis

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

137.8
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 109.9
1870 Female, age 42, unknown 143.4
1833 Male, age 53, unknown 120.4
1830 Male, age 51, unknown 113.7
1827 Male, age 72, unknown 111.6
2666 Male, age 74, left hemisphere 110.0
2411 Female, age 72, unknown 107.8
2219 Male, age 76, both hemispheres 105.3
2828 Female, age 72, unknown 102.7
2019 Male, age 18, unknown 101.4
2586 Male, age 75, left hemisphere 83.3
Dorsal raphe nucleus
nTPM: 122.7
2750 Male, age 76, both hemispheres 127.7
2016 Female, age 72, unknown 124.1
2047 Male, age 72, unknown 122.2
1828 Male, age 53, unknown 120.3
2298 Female, age 72, unknown 119.4
Inferior colliculus
nTPM: 131.7
2849 Male, age 72, unknown 144.0
2097 Female, age 72, unknown 132.5
1848 Female, age 42, unknown 128.5
1890 Male, age 53, unknown 121.6
Median raphe nucleus
nTPM: 137.8
2220 Male, age 76, midline 137.8
Periaquaductal grey, anterior
nTPM: 113.3
1947 Male, age 18, unknown 119.2
2502 Female, age 75, unknown 111.5
1795 Male, age 51, unknown 109.2
Periaquaductal grey, dorsal
nTPM: 126.0
2850 Male, age 76, both hemispheres 149.4
1840 Male, age 53, unknown 137.8
1831 Male, age 72, unknown 112.8
2464 Female, age 72, unknown 103.8
Periaquaductal grey, lateral
nTPM: 116.4
2140 Male, age 76, both hemispheres 127.1
2053 Male, age 18, unknown 125.6
2272 Male, age 74, both hemispheres 96.5
Pretectal area
nTPM: 123.2
2667 Female, age 75, unknown 142.1
2224 Female, age 72, unknown 138.6
1817 Female, age 42, unknown 130.0
2407 Male, age 75, both hemispheres 128.0
2825 Male, age 18, unknown 126.4
1944 Female, age 72, unknown 123.0
1815 Male, age 53, unknown 118.5
1816 Male, age 51, unknown 117.5
2007 Male, age 72, unknown 113.2
2273 Male, age 74, both hemispheres 109.4
2316 Male, age 76, right hemisphere 109.0
Red nucleus
nTPM: 124.2
2725 Female, age 75, unknown 148.5
1821 Female, age 72, unknown 141.1
1865 Male, age 51, unknown 135.2
2227 Male, age 72, unknown 129.9
1954 Female, age 42, unknown 129.0
2503 Female, age 72, unknown 128.6
1904 Male, age 53, unknown 123.8
2769 Male, age 72, unknown 122.0
2823 Male, age 76, right hemisphere 118.6
2584 Male, age 75, left hemisphere 109.5
2588 Male, age 74, left hemisphere 104.1
2785 Male, age 18, unknown 100.1
Substantia nigra
nTPM: 129.3
2699 Male, age 18, unknown 156.4
2665 Male, age 74, both hemispheres 149.6
1916 Female, age 42, unknown 146.2
1889 Female, age 72, unknown 142.1
2241 Male, age 72, unknown 129.1
1851 Male, age 51, unknown 128.7
1941 Male, age 53, unknown 128.3
2590 Female, age 75, unknown 108.9
2409 Female, age 72, unknown 105.0
2583 Male, age 75, right hemisphere 98.8
Superior colliculus
nTPM: 116.4
1895 Male, age 76, right hemisphere 136.8
2587 Male, age 74, left hemisphere 135.8
1913 Female, age 42, unknown 124.9
1839 Male, age 51, unknown 119.7
1995 Male, age 72, unknown 118.3
1796 Male, age 53, unknown 110.3
2664 Male, age 75, both hemispheres 107.5
2261 Male, age 18, unknown 106.4
2087 Female, age 72, unknown 105.3
2668 Female, age 75, unknown 99.2
Ventral tegmental area
nTPM: 125.1
2223 Female, age 72, unknown 142.2
1915 Female, age 42, unknown 137.2
2218 Male, age 76, both hemispheres 124.5
2021 Male, age 53, unknown 121.6
1942 Male, age 51, unknown 113.6
2410 Female, age 72, unknown 111.3

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

465.0
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 465.0
Samples: 139

Max nTPM: 995.6
Min nTPM: 257.0
Std nTPM: 126.5
Median nTPM: 447.8
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 995.6
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 890.9
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 873.5
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 804.5
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 772.3
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 732.3
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 709.7
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 686.6
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 655.8
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 613.6
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 613.0
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 610.7
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 609.6
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 608.8
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 606.1
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 603.2
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 594.4
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 584.7
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 580.6
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 579.8
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 574.5
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 572.2
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 566.1
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 563.5
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 558.4
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 556.5
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 555.5
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 553.7
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 550.3
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 547.2
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 541.4
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 538.6
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 538.3
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 536.9
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 535.2
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 533.0
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 522.8
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 521.2
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 518.3
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 517.5
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 516.9
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 507.0
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 504.4
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 499.8
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 499.5
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 498.3
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 498.0
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 497.8
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 494.6
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 492.6
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 491.4
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 489.7
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 484.7
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 483.5
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 482.8
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 482.8
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 475.5
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 474.5
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 473.1
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 472.4
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 472.1
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 468.3
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 467.5
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 465.2
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 464.1
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 460.4
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 458.1
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 454.9
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 449.6
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 447.8
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 442.4
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 439.8
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 437.1
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 435.6
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 434.7
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 434.4
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 433.8
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 433.2
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 431.4
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 428.3
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 427.9
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 427.6
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 427.2
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 426.9
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 426.0
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 423.2
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 420.3
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 419.9
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 416.4
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 413.0
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 412.2
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 412.1
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 408.9
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 407.1
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 406.1
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 404.7
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 402.5
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 399.4
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 396.0
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 394.6
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 386.2
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 382.7
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 380.0
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 379.0
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 378.0
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 377.1
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 375.5
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 370.1
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 369.2
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 366.3
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 364.0
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 362.7
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 361.9
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 354.5
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 351.7
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 351.3
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 345.8
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 342.1
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 341.9
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 341.5
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 340.7
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 339.2
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 333.7
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 332.3
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 329.0
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 321.7
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 314.1
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 313.4
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 312.0
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 311.0
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 280.0
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 277.0
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 276.0
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 274.2
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 272.0
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 265.3
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 262.4
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 259.8
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 257.0
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

75.1
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 75.1
FF:10158-103A5 76 years, female 75.1

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

172.6
Pig sample Sample description nTPM
Substantia nigra
nTPM: 172.6
Samples: 4

Max nTPM: 219.2
Min nTPM: 130.0
Sample A Female 219.2
Sample B Female 175.8
Sample C Male 165.4
Sample D Male 130.0
Midbrain
nTPM: 155.5
Samples: 4

Max nTPM: 174.6
Min nTPM: 137.8
Sample A Female 174.6
Sample B Female 166.5
Sample C Male 137.8
Sample D Male 142.9
Periaqueductal gray
nTPM: 153.0
Samples: 3

Max nTPM: 168.7
Min nTPM: 141.2
Sample B Female 141.2
Sample C Male 168.7
Sample D Male 149.0
Superior colliculi
nTPM: 161.6
Samples: 4

Max nTPM: 210.4
Min nTPM: 123.7
Sample A Female 210.4
Sample B Female 123.7
Sample C Male 172.9
Sample D Male 139.4

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

115.4
Mouse sample Sample description nTPM
Midbrain
nTPM: 115.4
Samples: 4

Max nTPM: 126.0
Min nTPM: 98.9
Sample A Male 126.0
Sample B Male 117.6
Sample C Female 98.9
Sample D Female 119.0

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

0.1
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 0.1
71763951 Antisense, RP_050921_02_H07, Mouse strain C57BL/6J (56 days, male) 0.1

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