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  • PNMA2
TISSUE PRIMARY DATA MIDBRAIN Show tissue menu
ADIPOSE TISSUE ADRENAL GLAND AMYGDALA APPENDIX BASAL GANGLIA BONE MARROW BREAST BRONCHUS CEREBELLUM CEREBRAL CORTEX CERVIX CHOROID PLEXUS COLON DUODENUM
ENDOMETRIUM EPIDIDYMIS ESOPHAGUS FALLOPIAN TUBE GALLBLADDER HEART MUSCLE HIPPOCAMPAL FORMATION HYPOTHALAMUS KIDNEY LIVER LUNG LYMPH NODE MIDBRAIN NASOPHARYNX
ORAL MUCOSA OVARY PANCREAS PARATHYROID GLAND PITUITARY GLAND PLACENTA PROSTATE RECTUM RETINA SALIVARY GLAND SEMINAL VESICLE SKELETAL MUSCLE SKIN SMALL INTESTINE
SMOOTH MUSCLE SOFT TISSUE SPINAL CORD SPLEEN STOMACH TESTIS THYMUS THYROID GLAND TONGUE TONSIL URINARY BLADDER VAGINA
ANTIBODIES
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VALIDATION
Dictionary
Tissue proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:35.1 nTPM
HPA Brain:121.2 nTPM
GTEx:35.1 nTPM
FANTOM5:23.6 Scaled Tags Per Million
Pig:42.9 nTPM
Mouse:22.5 nTPM
Allen mouse:0.3 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

121.2
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 81.9
1827 Male, age 72, unknown 111.0
2411 Female, age 72, unknown 92.7
1870 Female, age 42, unknown 91.1
2586 Male, age 75, left hemisphere 86.3
1833 Male, age 53, unknown 80.1
2666 Male, age 74, left hemisphere 79.2
2219 Male, age 76, both hemispheres 74.2
1830 Male, age 51, unknown 72.5
2828 Female, age 72, unknown 70.7
2019 Male, age 18, unknown 60.8
Dorsal raphe nucleus
nTPM: 95.3
2298 Female, age 72, unknown 126.3
2047 Male, age 72, unknown 96.4
1828 Male, age 53, unknown 90.5
2016 Female, age 72, unknown 86.2
2750 Male, age 76, both hemispheres 77.2
Inferior colliculus
nTPM: 115.5
2097 Female, age 72, unknown 136.0
2849 Male, age 72, unknown 124.9
1848 Female, age 42, unknown 117.4
1890 Male, age 53, unknown 83.8
Median raphe nucleus
nTPM: 117.6
2220 Male, age 76, midline 117.6
Periaquaductal grey, anterior
nTPM: 121.2
2502 Female, age 75, unknown 142.0
1947 Male, age 18, unknown 115.5
1795 Male, age 51, unknown 106.1
Periaquaductal grey, dorsal
nTPM: 114.1
1840 Male, age 53, unknown 147.6
2850 Male, age 76, both hemispheres 110.8
1831 Male, age 72, unknown 100.4
2464 Female, age 72, unknown 97.7
Periaquaductal grey, lateral
nTPM: 107.8
2140 Male, age 76, both hemispheres 114.4
2053 Male, age 18, unknown 107.5
2272 Male, age 74, both hemispheres 101.7
Pretectal area
nTPM: 100.9
2224 Female, age 72, unknown 133.3
1816 Male, age 51, unknown 114.6
2825 Male, age 18, unknown 114.4
2273 Male, age 74, both hemispheres 110.5
1944 Female, age 72, unknown 104.2
2316 Male, age 76, right hemisphere 97.7
2407 Male, age 75, both hemispheres 97.6
2007 Male, age 72, unknown 94.5
1815 Male, age 53, unknown 84.3
1817 Female, age 42, unknown 84.2
2667 Female, age 75, unknown 74.5
Red nucleus
nTPM: 51.8
2584 Male, age 75, left hemisphere 72.9
2725 Female, age 75, unknown 64.8
2785 Male, age 18, unknown 58.1
1821 Female, age 72, unknown 56.2
2769 Male, age 72, unknown 54.3
2227 Male, age 72, unknown 54.1
1954 Female, age 42, unknown 50.3
2503 Female, age 72, unknown 46.1
2588 Male, age 74, left hemisphere 43.4
2823 Male, age 76, right hemisphere 42.1
1865 Male, age 51, unknown 39.6
1904 Male, age 53, unknown 39.2
Substantia nigra
nTPM: 85.1
1941 Male, age 53, unknown 114.4
2241 Male, age 72, unknown 100.5
1916 Female, age 42, unknown 94.7
2590 Female, age 75, unknown 89.8
2665 Male, age 74, both hemispheres 89.5
1889 Female, age 72, unknown 89.4
1851 Male, age 51, unknown 79.8
2699 Male, age 18, unknown 68.7
2583 Male, age 75, right hemisphere 66.3
2409 Female, age 72, unknown 57.8
Superior colliculus
nTPM: 90.9
2664 Male, age 75, both hemispheres 125.6
1839 Male, age 51, unknown 112.9
2261 Male, age 18, unknown 112.0
1796 Male, age 53, unknown 104.3
1895 Male, age 76, right hemisphere 104.3
2087 Female, age 72, unknown 94.5
2587 Male, age 74, left hemisphere 81.6
2668 Female, age 75, unknown 72.1
1913 Female, age 42, unknown 53.5
1995 Male, age 72, unknown 48.6
Ventral tegmental area
nTPM: 91.9
2218 Male, age 76, both hemispheres 104.5
1942 Male, age 51, unknown 103.6
1915 Female, age 42, unknown 94.7
2021 Male, age 53, unknown 92.2
2223 Female, age 72, unknown 80.8
2410 Female, age 72, unknown 75.9

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

35.1
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 35.1
Samples: 139

Max nTPM: 140.1
Min nTPM: 3.8
Std nTPM: 20.8
Median nTPM: 30.0
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 140.1
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 120.1
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 88.6
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 88.6
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 83.5
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 81.0
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 80.6
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 73.9
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 71.3
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 71.2
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 70.7
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 66.0
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 64.4
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 64.3
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 62.1
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 57.3
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 54.7
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 54.3
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 53.9
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 51.3
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 50.8
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 49.1
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 48.4
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 48.0
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 47.8
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 47.6
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 46.3
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 45.3
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 45.1
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 45.0
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 45.0
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 44.9
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 44.9
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 44.3
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 42.9
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 42.8
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 42.7
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 42.6
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 42.2
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 42.1
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 41.6
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 41.1
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 40.8
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 40.0
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 38.9
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 38.7
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 38.4
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 38.0
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 37.5
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 37.2
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 37.2
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 36.8
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 36.4
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 35.2
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 34.4
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 34.2
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 34.2
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 34.1
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 33.8
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 33.6
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 32.6
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 32.1
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 32.0
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 31.9
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 31.6
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 31.4
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 30.7
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 30.6
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 30.0
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 30.0
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 29.9
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 29.5
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 28.5
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 28.0
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 27.8
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 27.6
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 27.5
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 27.0
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 26.8
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 26.6
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 26.3
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 26.2
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 25.8
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 25.5
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 25.2
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 24.9
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 24.8
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 24.7
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 24.6
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 24.6
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 24.0
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 24.0
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 23.8
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 23.8
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 23.4
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 23.4
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 23.4
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 23.3
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 22.9
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 22.9
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 22.9
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 22.8
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 22.7
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 22.5
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 22.3
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 22.1
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 21.5
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 20.1
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 19.8
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 19.8
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 19.4
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 19.4
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 19.3
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 19.3
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 19.2
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 18.6
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 18.2
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 18.1
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 17.8
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 17.7
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 17.2
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 17.2
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 17.1
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 16.7
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 16.2
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 15.8
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 15.2
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 15.1
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 14.6
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 14.0
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 13.8
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 13.5
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 13.4
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 11.9
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 11.7
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 8.4
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 7.2
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 6.9
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 3.8
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

23.6
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 23.6
FF:10158-103A5 76 years, female 23.6

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

42.9
Pig sample Sample description nTPM
Substantia nigra
nTPM: 31.8
Samples: 4

Max nTPM: 52.6
Min nTPM: 8.7
Sample A Female 52.6
Sample B Female 21.1
Sample C Male 44.8
Sample D Male 8.7
Midbrain
nTPM: 38.7
Samples: 4

Max nTPM: 57.6
Min nTPM: 10.2
Sample A Female 10.2
Sample B Female 30.8
Sample C Male 56.1
Sample D Male 57.6
Periaqueductal gray
nTPM: 32.2
Samples: 3

Max nTPM: 41.2
Min nTPM: 26.5
Sample B Female 29.0
Sample C Male 41.2
Sample D Male 26.5
Superior colliculi
nTPM: 42.9
Samples: 4

Max nTPM: 60.3
Min nTPM: 17.1
Sample A Female 60.3
Sample B Female 17.1
Sample C Male 52.7
Sample D Male 41.6

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

22.5
Mouse sample Sample description nTPM
Midbrain
nTPM: 22.5
Samples: 4

Max nTPM: 23.5
Min nTPM: 21.3
Sample A Male 21.3
Sample B Male 23.3
Sample C Female 21.7
Sample D Female 23.5

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

0.3
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 0.3
69816374 Antisense, RP_050505_04_H07, Mouse strain C57BL/6J (56 days, male) 0.3

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