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BRAIN BASAL GANGLIA Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
AND
VALIDATION
Brain proteome
Basal ganglia
BASAL GANGLIA - Expression summary
Protein expression
Caudatei

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

h
m
l
n
Glial cells: High
Neuronal cells: High
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
HPA Brain:142.2 nTPM
FANTOM5:10.7 Scaled Tags Per Million
Pig:141.3 nTPM
Mouse:1.6 nTPM
Allen mouse:13.4 Expression energy

CAUDATE - Antibody stainingi

Antibody staining in the annotated cell types in the current human tissue is reported as not detected, low, medium, or high, based on conventional immunohistochemistry profiling in selected tissues. This score is based on the combination of the staining intensity and fraction of stained cells.

Each image is clickable and will lead to virtual microscopy that enables deeper exploration of all samples and also displays staining intensity scores, fraction scores and subcellular localization as well as patient and tissue information for each sample.

Antibody HPA041189
Glial cells High
Neuronal cells High



BASAL GANGLIA - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

142.2
Sample id Sample description nTPM
Caudate nucleus
nTPM: 138.1
2289 Male, age 61, right hemisphere 177.6
1781 Male, age 74, unknown 158.6
2481 Female, age 94, left hemisphere 136.3
2290 Female, age 72, unknown 132.8
2846 Female, age 79, unknown 132.6
1857 Female, age 85, left hemisphere 130.1
2288 Male, age 75, left hemisphere 128.7
1854 Male, age 80, left hemisphere 108.5
Globus pallidus, externus
nTPM: 125.8
2646 Male, age 61, right hemisphere 180.3
1996 Male, age 80, right hemisphere 138.9
2772 Female, age 79, unknown 120.7
2395 Male, age 75, both hemispheres 115.5
2567 Female, age 72, unknown 73.5
Globus pallidus, internus
nTPM: 130.9
2111 Female, age 85, right hemisphere 147.4
2483 Female, age 94, right hemisphere 147.3
2566 Female, age 72, unknown 137.6
2778 Female, age 91, both hemispheres 125.6
1818 Male, age 74, unknown 122.1
2037 Male, age 80, right hemisphere 122.0
2287 Male, age 75, right hemisphere 114.4
Nucleus accumbens
nTPM: 133.4
2286 Male, age 75, left hemisphere 145.8
1783 Male, age 74, unknown 144.3
1806 Female, age 85, left hemisphere 141.7
2732 Male, age 80, right hemisphere 136.5
2824 Male, age 61, right hemisphere 136.1
2391 Female, age 94, left hemisphere 130.2
2698 Female, age 72, unknown 117.5
1856 Female, age 91, right hemisphere 114.8
Nucleus basalis of Meynert
nTPM: 142.2
2569 Male, age 61, both hemispheres 195.4
2484 Female, age 94, left hemisphere 141.6
2821 Male, age 75, both hemispheres 117.4
2393 Male, age 80, right hemisphere 114.5
Nucleus of the diagonal band
nTPM: 103.5
1979 Male, age 74, unknown 149.5
1812 Female, age 91, both hemispheres 115.5
2775 Male, age 80, right hemisphere 96.3
2195 Female, age 85, both hemispheres 93.2
2029 Male, age 61, right hemisphere 63.2
Putamen
nTPM: 118.4
2482 Female, age 94, left hemisphere 151.6
2647 Male, age 75, left hemisphere 146.6
2466 Female, age 79, unknown 130.1
1937 Female, age 91, right hemisphere 118.5
2489 Female, age 72, unknown 107.1
1838 Male, age 80, right hemisphere 88.4
1829 Male, age 74, unknown 86.6
Septal nuclei
nTPM: 117.9
2199 Male, age 80, right hemisphere 173.8
2059 Female, age 85, both hemispheres 128.5
2031 Female, age 72, unknown 116.9
2009 Female, age 91, both hemispheres 106.1
2394 Male, age 61, left hemisphere 103.5
1960 Male, age 74, unknown 101.5
2629 Female, age 94, right hemisphere 95.2
Stria terminalis, bed nucleus
nTPM: 88.4
2486 Female, age 94, both hemispheres 91.8
1974 Female, age 91, both hemispheres 87.1
2201 Male, age 74, unknown 86.2

BASAL GANGLIA - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

10.7
FANTOM5 sample id Sample description Scaled Tags Per Million
Caudate nucleus
Scaled Tags Per Million: 5.2
FF:10164-103B2 76 years, female 5.2
Nucleus accumbens
Scaled Tags Per Million: 4.1
FF:10037-101F1 23-56 years, mixed 4.1
Putamen
Scaled Tags Per Million: 3.3
FF:10176-103C5 60 years, female 3.3
Globus pallidus
Scaled Tags Per Million: 10.7
FF:10175-103C4 60 years, female 17.2
FF:10161-103A8 76 years, female 4.3

BASAL GANGLIA - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

141.3
Pig sample Sample description nTPM
Caudate
nTPM: 141.3
Samples: 4

Max nTPM: 154.7
Min nTPM: 125.5
Sample A Female 134.9
Sample B Female 154.7
Sample C Male 150.0
Sample D Male 125.5
Putamen
nTPM: 112.2
Samples: 4

Max nTPM: 163.9
Min nTPM: 86.7
Sample A Female 92.9
Sample B Female 86.7
Sample C Male 163.9
Sample D Male 105.2
Septum
nTPM: 97.2
Samples: 4

Max nTPM: 130.2
Min nTPM: 64.1
Sample A Female 130.2
Sample B Female 111.9
Sample C Male 64.1
Sample D Male 82.6
Ventral pallidum
nTPM: 89.9
Samples: 4

Max nTPM: 130.6
Min nTPM: 51.4
Sample A Female 94.4
Sample B Female 130.6
Sample C Male 51.4
Sample D Male 83.0

BASAL GANGLIA - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

1.6
Mouse sample Sample description nTPM
Caudate putamen
nTPM: 0.7
Samples: 4

Max nTPM: 2.9
Min nTPM: 0.0
Sample A Male 0.0
Sample B Male 2.9
Sample C Female 0.0
Sample D Female 0.0
Septum
nTPM: 1.3
Samples: 4

Max nTPM: 2.2
Min nTPM: 0.0
Sample A Male 1.9
Sample B Male 1.1
Sample C Female 0.0
Sample D Female 2.2
Ventral forebrain
nTPM: 1.6
Samples: 4

Max nTPM: 2.8
Min nTPM: 0.0
Sample A Male 2.2
Sample B Male 0.0
Sample C Female 1.5
Sample D Female 2.8

BASAL GANGLIA - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

13.4
Allen experiment id Experiment description Expression energy
Striatum
Expression energy: 13.4
69169367 Antisense, RP_050321_03_D08, Mouse strain C57BL/6J (56 days, male) 13.5
72129296 Antisense, RP_051017_03_F12, Mouse strain C57BL/6J (56 days, male) 13.3
Pallidum
Expression energy: 12.4
69169367 Antisense, RP_050321_03_D08, Mouse strain C57BL/6J (56 days, male) 13.6
72129296 Antisense, RP_051017_03_F12, Mouse strain C57BL/6J (56 days, male) 11.2

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