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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
AND
VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
HPA Brain:160.7 nTPM
FANTOM5:4.4 Scaled Tags Per Million
Pig:93.6 nTPM
Mouse:0.2 nTPM
Allen mouse:11.7 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

160.7
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 112.5
2019 Male, age 18, unknown 135.7
2219 Male, age 76, both hemispheres 128.9
2586 Male, age 75, left hemisphere 117.5
1830 Male, age 51, unknown 115.4
2411 Female, age 72, unknown 108.6
1833 Male, age 53, unknown 108.0
2828 Female, age 72, unknown 108.0
1827 Male, age 72, unknown 104.1
1870 Female, age 42, unknown 99.4
2666 Male, age 74, left hemisphere 99.2
Dorsal raphe nucleus
nTPM: 150.3
2298 Female, age 72, unknown 217.8
2016 Female, age 72, unknown 185.1
1828 Male, age 53, unknown 142.2
2750 Male, age 76, both hemispheres 108.4
2047 Male, age 72, unknown 98.2
Inferior colliculus
nTPM: 113.0
2097 Female, age 72, unknown 149.1
1890 Male, age 53, unknown 117.8
2849 Male, age 72, unknown 94.9
1848 Female, age 42, unknown 90.3
Median raphe nucleus
nTPM: 97.6
2220 Male, age 76, midline 97.6
Periaquaductal grey, anterior
nTPM: 130.0
2502 Female, age 75, unknown 144.9
1795 Male, age 51, unknown 133.3
1947 Male, age 18, unknown 111.7
Periaquaductal grey, dorsal
nTPM: 139.4
1831 Male, age 72, unknown 174.1
2850 Male, age 76, both hemispheres 148.9
2464 Female, age 72, unknown 121.6
1840 Male, age 53, unknown 113.1
Periaquaductal grey, lateral
nTPM: 160.7
2272 Male, age 74, both hemispheres 212.5
2140 Male, age 76, both hemispheres 156.7
2053 Male, age 18, unknown 112.7
Pretectal area
nTPM: 125.3
2273 Male, age 74, both hemispheres 181.3
2224 Female, age 72, unknown 174.3
2316 Male, age 76, right hemisphere 131.7
1815 Male, age 53, unknown 123.3
2407 Male, age 75, both hemispheres 121.4
1816 Male, age 51, unknown 117.4
2007 Male, age 72, unknown 113.0
1817 Female, age 42, unknown 108.5
2667 Female, age 75, unknown 104.5
1944 Female, age 72, unknown 102.1
2825 Male, age 18, unknown 101.2
Red nucleus
nTPM: 119.9
1865 Male, age 51, unknown 143.9
2769 Male, age 72, unknown 141.8
2227 Male, age 72, unknown 139.0
2785 Male, age 18, unknown 138.2
2503 Female, age 72, unknown 137.4
1904 Male, age 53, unknown 132.7
1954 Female, age 42, unknown 111.7
1821 Female, age 72, unknown 110.9
2725 Female, age 75, unknown 108.9
2823 Male, age 76, right hemisphere 108.1
2584 Male, age 75, left hemisphere 87.6
2588 Male, age 74, left hemisphere 78.9
Substantia nigra
nTPM: 118.9
2699 Male, age 18, unknown 189.0
1851 Male, age 51, unknown 136.7
2665 Male, age 74, both hemispheres 136.1
1916 Female, age 42, unknown 115.9
2590 Female, age 75, unknown 111.7
2409 Female, age 72, unknown 102.7
1889 Female, age 72, unknown 102.1
1941 Male, age 53, unknown 100.7
2583 Male, age 75, right hemisphere 98.3
2241 Male, age 72, unknown 95.8
Superior colliculus
nTPM: 132.4
1995 Male, age 72, unknown 175.1
1913 Female, age 42, unknown 163.7
2668 Female, age 75, unknown 153.8
1796 Male, age 53, unknown 140.4
2587 Male, age 74, left hemisphere 134.6
2664 Male, age 75, both hemispheres 130.0
2087 Female, age 72, unknown 121.3
2261 Male, age 18, unknown 109.1
1839 Male, age 51, unknown 100.3
1895 Male, age 76, right hemisphere 96.0
Ventral tegmental area
nTPM: 144.7
1915 Female, age 42, unknown 169.7
2021 Male, age 53, unknown 162.8
2410 Female, age 72, unknown 143.1
2223 Female, age 72, unknown 140.1
1942 Male, age 51, unknown 127.9
2218 Male, age 76, both hemispheres 124.4

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

4.4
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 4.4
FF:10158-103A5 76 years, female 4.4

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

93.6
Pig sample Sample description nTPM
Substantia nigra
nTPM: 75.4
Samples: 4

Max nTPM: 103.0
Min nTPM: 56.9
Sample A Female 103.0
Sample B Female 80.3
Sample C Male 61.5
Sample D Male 56.9
Midbrain
nTPM: 79.0
Samples: 4

Max nTPM: 111.2
Min nTPM: 65.0
Sample A Female 111.2
Sample B Female 70.1
Sample C Male 65.0
Sample D Male 69.6
Periaqueductal gray
nTPM: 65.5
Samples: 3

Max nTPM: 77.8
Min nTPM: 58.1
Sample B Female 58.1
Sample C Male 77.8
Sample D Male 60.6
Superior colliculi
nTPM: 93.6
Samples: 4

Max nTPM: 117.9
Min nTPM: 69.8
Sample A Female 117.9
Sample B Female 113.6
Sample C Male 73.0
Sample D Male 69.8

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

0.2
Mouse sample Sample description nTPM
Midbrain
nTPM: 0.3
Samples: 4

Max nTPM: 1.0
Min nTPM: 0.0
Sample A Male 0.0
Sample B Male 1.0
Sample C Female 0.0
Sample D Female 0.0

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

11.7
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 11.7
69169367 Antisense, RP_050321_03_D08, Mouse strain C57BL/6J (56 days, male) 12.8
72129296 Antisense, RP_051017_03_F12, Mouse strain C57BL/6J (56 days, male) 10.6

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