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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
HPA Brain:284.8 nTPM
FANTOM5:366.0 Scaled Tags Per Million
Pig:102.2 nTPM
Mouse:67.0 nTPM
Allen mouse:11.8 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

284.8
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 189.6
2019 Male, age 18, unknown 237.9
2828 Female, age 72, unknown 227.0
1827 Male, age 72, unknown 223.7
2586 Male, age 75, left hemisphere 221.8
1870 Female, age 42, unknown 193.8
1833 Male, age 53, unknown 182.5
2411 Female, age 72, unknown 175.6
1830 Male, age 51, unknown 173.3
2666 Male, age 74, left hemisphere 149.9
2219 Male, age 76, both hemispheres 110.9
Dorsal raphe nucleus
nTPM: 229.7
2047 Male, age 72, unknown 261.1
2298 Female, age 72, unknown 241.1
1828 Male, age 53, unknown 239.3
2016 Female, age 72, unknown 208.8
2750 Male, age 76, both hemispheres 198.4
Inferior colliculus
nTPM: 219.4
1890 Male, age 53, unknown 229.0
2097 Female, age 72, unknown 222.6
1848 Female, age 42, unknown 213.1
2849 Male, age 72, unknown 213.0
Median raphe nucleus
nTPM: 281.7
2220 Male, age 76, midline 281.7
Periaquaductal grey, anterior
nTPM: 238.4
1795 Male, age 51, unknown 248.5
2502 Female, age 75, unknown 241.8
1947 Male, age 18, unknown 224.8
Periaquaductal grey, dorsal
nTPM: 229.8
2850 Male, age 76, both hemispheres 325.0
1840 Male, age 53, unknown 230.0
1831 Male, age 72, unknown 191.3
2464 Female, age 72, unknown 172.8
Periaquaductal grey, lateral
nTPM: 284.8
2140 Male, age 76, both hemispheres 379.3
2272 Male, age 74, both hemispheres 263.9
2053 Male, age 18, unknown 211.3
Pretectal area
nTPM: 254.8
2407 Male, age 75, both hemispheres 414.4
1816 Male, age 51, unknown 276.0
1944 Female, age 72, unknown 268.7
2007 Male, age 72, unknown 268.3
2316 Male, age 76, right hemisphere 260.5
1817 Female, age 42, unknown 242.6
2273 Male, age 74, both hemispheres 241.2
2667 Female, age 75, unknown 224.5
2224 Female, age 72, unknown 213.3
2825 Male, age 18, unknown 200.8
1815 Male, age 53, unknown 192.0
Red nucleus
nTPM: 198.8
2725 Female, age 75, unknown 261.8
2785 Male, age 18, unknown 226.6
1821 Female, age 72, unknown 206.1
2227 Male, age 72, unknown 203.2
2823 Male, age 76, right hemisphere 203.2
2769 Male, age 72, unknown 201.5
2503 Female, age 72, unknown 198.5
1954 Female, age 42, unknown 189.5
1904 Male, age 53, unknown 181.9
1865 Male, age 51, unknown 175.4
2584 Male, age 75, left hemisphere 170.7
2588 Male, age 74, left hemisphere 167.1
Substantia nigra
nTPM: 235.4
1916 Female, age 42, unknown 327.4
1851 Male, age 51, unknown 269.3
1941 Male, age 53, unknown 256.8
1889 Female, age 72, unknown 244.1
2409 Female, age 72, unknown 233.3
2699 Male, age 18, unknown 223.1
2241 Male, age 72, unknown 213.4
2590 Female, age 75, unknown 207.6
2665 Male, age 74, both hemispheres 193.7
2583 Male, age 75, right hemisphere 185.3
Superior colliculus
nTPM: 213.8
2664 Male, age 75, both hemispheres 292.4
2261 Male, age 18, unknown 255.6
1796 Male, age 53, unknown 249.8
2087 Female, age 72, unknown 248.4
2587 Male, age 74, left hemisphere 197.2
2668 Female, age 75, unknown 193.8
1839 Male, age 51, unknown 181.3
1995 Male, age 72, unknown 176.0
1913 Female, age 42, unknown 174.5
1895 Male, age 76, right hemisphere 168.6
Ventral tegmental area
nTPM: 224.7
1915 Female, age 42, unknown 267.4
2218 Male, age 76, both hemispheres 234.8
1942 Male, age 51, unknown 232.5
2021 Male, age 53, unknown 215.7
2410 Female, age 72, unknown 206.7
2223 Female, age 72, unknown 191.4

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

366.0
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 366.0
FF:10158-103A5 76 years, female 366.0

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

102.2
Pig sample Sample description nTPM
Substantia nigra
nTPM: 83.0
Samples: 4

Max nTPM: 116.8
Min nTPM: 52.7
Sample A Female 116.8
Sample B Female 65.3
Sample C Male 97.1
Sample D Male 52.7
Midbrain
nTPM: 85.1
Samples: 4

Max nTPM: 97.2
Min nTPM: 70.7
Sample A Female 78.5
Sample B Female 70.7
Sample C Male 93.8
Sample D Male 97.2
Periaqueductal gray
nTPM: 68.9
Samples: 3

Max nTPM: 76.5
Min nTPM: 61.2
Sample B Female 68.9
Sample C Male 76.5
Sample D Male 61.2
Superior colliculi
nTPM: 102.2
Samples: 4

Max nTPM: 124.4
Min nTPM: 78.0
Sample A Female 124.4
Sample B Female 78.0
Sample C Male 118.6
Sample D Male 87.6

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

67.0
Mouse sample Sample description nTPM
Midbrain
nTPM: 67.0
Samples: 4

Max nTPM: 72.8
Min nTPM: 62.0
Sample A Male 62.0
Sample B Male 69.0
Sample C Female 72.8
Sample D Female 64.0

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

11.8
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 11.8
634450 Antisense, RP_040907_02_H11, Mouse strain C57BL/6J (56 days, male) 11.8

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