In this episode of Proteins Unfolded Evelina Sjöstedt, head of Single cell analysis at the Human Protein Atlas, joins the hosts PhD students Andrea Villanueva Raisman and Emilio Skarwan to explore the transcriptome, the bridge between our static DNA and active proteins.

The discussion highlights the flexibility of the transcriptome and how external factors like stress, diet, and disease cause the transcriptome to shift, providing researchers with a "to-do list" of protein production in different parts of the human body.

Evelina also introduces the field of single-cell transcriptomics, which allows scientists to map gene activity within individual cells to enable decoding of complex tissues like brain.

All in all this episode underscore how studying both the transcriptome and the proteome can provide a more complete picture of biological health and disease.

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