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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:194.1 nTPM
HPA Brain:202.3 nTPM
GTEx:194.1 nTPM
FANTOM5:613.2 Scaled Tags Per Million
Pig:668.4 nTPM
Mouse:27.0 nTPM
Allen mouse:2.5 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

202.3
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 77.2
2019 Male, age 18, unknown 127.9
1870 Female, age 42, unknown 99.4
2666 Male, age 74, left hemisphere 96.5
2828 Female, age 72, unknown 86.8
1830 Male, age 51, unknown 84.9
1833 Male, age 53, unknown 83.8
2411 Female, age 72, unknown 59.4
1827 Male, age 72, unknown 54.9
2219 Male, age 76, both hemispheres 40.5
2586 Male, age 75, left hemisphere 37.9
Dorsal raphe nucleus
nTPM: 165.0
2016 Female, age 72, unknown 279.3
2298 Female, age 72, unknown 214.5
1828 Male, age 53, unknown 152.8
2047 Male, age 72, unknown 101.8
2750 Male, age 76, both hemispheres 76.8
Inferior colliculus
nTPM: 84.4
1890 Male, age 53, unknown 137.7
2097 Female, age 72, unknown 76.4
2849 Male, age 72, unknown 61.9
1848 Female, age 42, unknown 61.5
Median raphe nucleus
nTPM: 82.7
2220 Male, age 76, midline 82.7
Periaquaductal grey, anterior
nTPM: 138.3
1795 Male, age 51, unknown 215.3
2502 Female, age 75, unknown 112.4
1947 Male, age 18, unknown 87.0
Periaquaductal grey, dorsal
nTPM: 167.5
2850 Male, age 76, both hemispheres 307.2
1831 Male, age 72, unknown 197.0
1840 Male, age 53, unknown 86.1
2464 Female, age 72, unknown 79.6
Periaquaductal grey, lateral
nTPM: 202.3
2272 Male, age 74, both hemispheres 276.7
2140 Male, age 76, both hemispheres 207.7
2053 Male, age 18, unknown 122.5
Pretectal area
nTPM: 96.0
2273 Male, age 74, both hemispheres 251.5
2224 Female, age 72, unknown 125.8
2316 Male, age 76, right hemisphere 99.1
2825 Male, age 18, unknown 89.7
1817 Female, age 42, unknown 81.5
1815 Male, age 53, unknown 76.7
2667 Female, age 75, unknown 71.5
2407 Male, age 75, both hemispheres 71.3
2007 Male, age 72, unknown 64.5
1816 Male, age 51, unknown 62.4
1944 Female, age 72, unknown 62.3
Red nucleus
nTPM: 108.4
2785 Male, age 18, unknown 131.3
2725 Female, age 75, unknown 121.9
2769 Male, age 72, unknown 118.7
2227 Male, age 72, unknown 117.7
1821 Female, age 72, unknown 113.9
1904 Male, age 53, unknown 112.7
2584 Male, age 75, left hemisphere 111.5
1954 Female, age 42, unknown 109.7
1865 Male, age 51, unknown 107.4
2503 Female, age 72, unknown 91.6
2588 Male, age 74, left hemisphere 83.5
2823 Male, age 76, right hemisphere 80.9
Substantia nigra
nTPM: 101.1
2590 Female, age 75, unknown 145.2
2665 Male, age 74, both hemispheres 137.8
2699 Male, age 18, unknown 130.6
1851 Male, age 51, unknown 125.5
2583 Male, age 75, right hemisphere 101.9
2409 Female, age 72, unknown 82.9
1941 Male, age 53, unknown 79.5
1916 Female, age 42, unknown 74.7
2241 Male, age 72, unknown 68.6
1889 Female, age 72, unknown 64.5
Superior colliculus
nTPM: 116.7
1995 Male, age 72, unknown 287.0
1913 Female, age 42, unknown 181.6
2587 Male, age 74, left hemisphere 139.6
2087 Female, age 72, unknown 108.8
2668 Female, age 75, unknown 84.2
1796 Male, age 53, unknown 84.1
2664 Male, age 75, both hemispheres 80.0
2261 Male, age 18, unknown 79.2
1839 Male, age 51, unknown 68.7
1895 Male, age 76, right hemisphere 53.8
Ventral tegmental area
nTPM: 126.8
1915 Female, age 42, unknown 171.4
2223 Female, age 72, unknown 165.3
2021 Male, age 53, unknown 156.4
1942 Male, age 51, unknown 98.6
2218 Male, age 76, both hemispheres 90.0
2410 Female, age 72, unknown 78.8

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

194.1
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 194.1
Samples: 139

Max nTPM: 1102.3
Min nTPM: 57.3
Std nTPM: 143.2
Median nTPM: 158.4
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 1102.3
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 777.1
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 725.2
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 711.4
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 573.7
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 495.9
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 380.7
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 368.8
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 340.7
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 330.7
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 323.7
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 322.8
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 318.1
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 317.4
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 317.3
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 316.2
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 313.6
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 312.1
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 310.7
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 309.4
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 306.2
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 290.7
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 289.9
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 287.5
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 284.9
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 275.9
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 268.5
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 261.8
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 260.0
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 256.0
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 247.8
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 241.6
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 241.3
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 237.2
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 237.1
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 233.7
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 233.6
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 217.0
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 214.4
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 214.3
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 209.2
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 206.3
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 199.6
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 199.1
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 197.1
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 192.4
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 192.2
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 188.6
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 187.2
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 184.7
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 183.6
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 180.9
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 180.3
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 179.9
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 179.8
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 179.6
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 178.2
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 175.8
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 169.9
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 169.1
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 169.0
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 165.2
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 165.1
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 164.5
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 162.9
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 159.7
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 159.6
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 159.3
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 158.9
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 158.4
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 158.2
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 156.6
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 155.0
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 153.7
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 148.8
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 146.3
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 144.7
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 144.3
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 144.3
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 144.3
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 139.7
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 139.5
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 139.3
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 135.0
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 134.9
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 132.4
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 131.2
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 130.9
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 129.1
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 128.5
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 126.8
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 122.2
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 122.0
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 120.8
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 120.8
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 120.3
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 119.4
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 119.3
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 119.1
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 118.7
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 116.9
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 115.5
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 114.3
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 113.5
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 111.4
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 110.2
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 109.7
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 109.1
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 105.0
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 103.7
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 103.5
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 102.0
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 100.8
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 100.1
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 99.3
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 98.7
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 98.7
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 96.5
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 92.0
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 90.0
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 90.0
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 88.5
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 88.3
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 87.1
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 86.8
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 85.2
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 83.1
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 82.4
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 77.4
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 72.7
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 72.4
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 70.7
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 69.7
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 63.7
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 63.7
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 61.2
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 58.4
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 58.1
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 57.3
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MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

613.2
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 613.2
FF:10158-103A5 76 years, female 613.2

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

668.4
Pig sample Sample description nTPM
Substantia nigra
nTPM: 299.2
Samples: 4

Max nTPM: 750.3
Min nTPM: 86.7
Sample A Female 203.4
Sample B Female 750.3
Sample C Male 86.7
Sample D Male 156.5
Midbrain
nTPM: 120.8
Samples: 4

Max nTPM: 184.4
Min nTPM: 60.9
Sample A Female 184.4
Sample B Female 116.8
Sample C Male 121.0
Sample D Male 60.9
Periaqueductal gray
nTPM: 184.3
Samples: 3

Max nTPM: 222.9
Min nTPM: 156.7
Sample B Female 173.3
Sample C Male 222.9
Sample D Male 156.7
Superior colliculi
nTPM: 668.4
Samples: 4

Max nTPM: 1706.4
Min nTPM: 115.3
Sample A Female 736.2
Sample B Female 1706.4
Sample C Male 115.3
Sample D Male 115.8

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

27.0
Mouse sample Sample description nTPM
Midbrain
nTPM: 27.1
Samples: 4

Max nTPM: 33.6
Min nTPM: 23.5
Sample A Male 33.6
Sample B Male 25.5
Sample C Female 23.5
Sample D Female 25.6

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

2.5
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 2.5
79677371 Antisense, RP_071218_02_C05, Mouse strain C57BL/6J (56 days, male) 3.3
79677375 Antisense, RP_071218_02_C11, Mouse strain C57BL/6J (56 days, male) 2.9
1310 Antisense, RP_Baylor_103104, Mouse strain C57BL/6J (56 days, male) 1.3
79907904 Antisense, RP_071218_02_C05, Mouse strain C57BL/6J (56 days, male) 1.2
1309 Antisense, RP_Baylor_103104, Mouse strain C57BL/6J (56 days, male) 0.4

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