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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:698.8 nTPM
HPA Brain:812.9 nTPM
GTEx:698.8 nTPM
FANTOM5:1553.0 Scaled Tags Per Million
Pig:90.7 nTPM
Mouse:115.3 nTPM
Allen mouse:1.8 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

812.9
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 595.5
2411 Female, age 72, unknown 864.8
1830 Male, age 51, unknown 820.0
1870 Female, age 42, unknown 780.1
1833 Male, age 53, unknown 715.2
2019 Male, age 18, unknown 661.9
2828 Female, age 72, unknown 540.5
2666 Male, age 74, left hemisphere 436.8
1827 Male, age 72, unknown 434.3
2219 Male, age 76, both hemispheres 356.9
2586 Male, age 75, left hemisphere 344.2
Dorsal raphe nucleus
nTPM: 466.5
2750 Male, age 76, both hemispheres 905.9
2016 Female, age 72, unknown 454.3
1828 Male, age 53, unknown 407.3
2298 Female, age 72, unknown 297.1
2047 Male, age 72, unknown 268.0
Inferior colliculus
nTPM: 372.7
1848 Female, age 42, unknown 409.8
1890 Male, age 53, unknown 373.6
2849 Male, age 72, unknown 356.6
2097 Female, age 72, unknown 350.7
Median raphe nucleus
nTPM: 414.8
2220 Male, age 76, midline 414.8
Periaquaductal grey, anterior
nTPM: 351.2
1947 Male, age 18, unknown 410.3
2502 Female, age 75, unknown 399.6
1795 Male, age 51, unknown 243.8
Periaquaductal grey, dorsal
nTPM: 287.3
2464 Female, age 72, unknown 431.0
1831 Male, age 72, unknown 322.0
1840 Male, age 53, unknown 203.3
2850 Male, age 76, both hemispheres 192.9
Periaquaductal grey, lateral
nTPM: 298.3
2053 Male, age 18, unknown 354.4
2272 Male, age 74, both hemispheres 353.2
2140 Male, age 76, both hemispheres 187.3
Pretectal area
nTPM: 369.1
2316 Male, age 76, right hemisphere 556.4
1815 Male, age 53, unknown 524.1
2825 Male, age 18, unknown 409.8
1817 Female, age 42, unknown 408.9
2407 Male, age 75, both hemispheres 380.6
2007 Male, age 72, unknown 378.5
2273 Male, age 74, both hemispheres 376.5
2224 Female, age 72, unknown 327.9
2667 Female, age 75, unknown 274.9
1944 Female, age 72, unknown 221.2
1816 Male, age 51, unknown 201.3
Red nucleus
nTPM: 812.9
1865 Male, age 51, unknown 1104.4
1821 Female, age 72, unknown 1099.7
1904 Male, age 53, unknown 991.5
2823 Male, age 76, right hemisphere 891.3
2769 Male, age 72, unknown 825.0
1954 Female, age 42, unknown 822.3
2227 Male, age 72, unknown 812.4
2503 Female, age 72, unknown 800.7
2785 Male, age 18, unknown 704.5
2588 Male, age 74, left hemisphere 623.7
2725 Female, age 75, unknown 620.4
2584 Male, age 75, left hemisphere 458.3
Substantia nigra
nTPM: 460.4
1851 Male, age 51, unknown 614.4
2409 Female, age 72, unknown 560.5
2590 Female, age 75, unknown 541.3
1889 Female, age 72, unknown 516.3
2241 Male, age 72, unknown 475.9
2699 Male, age 18, unknown 450.6
2583 Male, age 75, right hemisphere 427.6
1916 Female, age 42, unknown 366.9
1941 Male, age 53, unknown 341.3
2665 Male, age 74, both hemispheres 309.6
Superior colliculus
nTPM: 491.7
1913 Female, age 42, unknown 786.3
1995 Male, age 72, unknown 675.0
1895 Male, age 76, right hemisphere 668.6
2587 Male, age 74, left hemisphere 586.4
2668 Female, age 75, unknown 530.8
1839 Male, age 51, unknown 501.4
1796 Male, age 53, unknown 368.3
2664 Male, age 75, both hemispheres 274.7
2087 Female, age 72, unknown 272.8
2261 Male, age 18, unknown 252.8
Ventral tegmental area
nTPM: 544.1
2223 Female, age 72, unknown 785.8
2410 Female, age 72, unknown 708.5
2021 Male, age 53, unknown 501.0
1915 Female, age 42, unknown 448.1
1942 Male, age 51, unknown 423.6
2218 Male, age 76, both hemispheres 397.8

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

698.8
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 698.8
Samples: 139

Max nTPM: 2254.6
Min nTPM: 239.8
Std nTPM: 378.8
Median nTPM: 584.6
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 2254.6
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 1852.9
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 1826.5
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 1714.4
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 1627.8
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 1598.1
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 1543.7
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 1438.2
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 1381.0
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 1354.7
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 1322.0
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 1316.7
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 1260.1
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 1257.8
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 1241.5
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 1218.6
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 1189.8
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 1152.3
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 1147.7
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 1146.2
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 1111.4
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 1109.7
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 1064.2
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 1030.0
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 1005.6
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 1004.7
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 992.0
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 988.4
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 955.8
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 932.0
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 923.3
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 921.2
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 919.9
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 884.7
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 884.2
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 857.2
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 835.8
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 823.8
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 802.6
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 799.5
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 790.5
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 771.4
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 768.4
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 753.9
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 747.1
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 746.8
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 746.1
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 736.3
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 723.0
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 721.3
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 715.7
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 708.3
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 691.7
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 646.4
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 646.1
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 640.8
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 632.1
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 628.8
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 616.6
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 615.0
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 613.6
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 612.9
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 606.8
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 606.4
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 606.3
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 605.0
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 593.6
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 586.9
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 586.5
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 584.6
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 583.5
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 579.3
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 573.7
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 571.5
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 565.5
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 553.3
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 547.6
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 545.7
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 542.7
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 540.0
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 537.7
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 527.4
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 522.8
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 516.9
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 516.0
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 513.5
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 510.3
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 509.2
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 508.4
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 504.2
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 485.0
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 484.8
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 478.4
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 477.1
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 474.9
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 473.4
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 464.3
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 463.4
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 449.6
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 445.8
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 443.0
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 436.1
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 435.3
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 428.3
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 427.3
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 424.2
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 423.9
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 417.5
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 409.5
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 398.7
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 392.9
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 391.9
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 391.6
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 385.3
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 383.7
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 383.4
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 378.5
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 377.7
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 377.1
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 375.4
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 371.6
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 366.1
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 363.8
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 351.6
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 342.9
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 330.3
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 328.4
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 313.4
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 301.7
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 299.0
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 299.0
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 298.3
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 292.8
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 289.4
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 281.4
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 272.9
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 265.4
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 243.3
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 239.8
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MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

1553.0
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 1553.0
FF:10158-103A5 76 years, female 1553.0

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

90.7
Pig sample Sample description nTPM
Substantia nigra
nTPM: 87.9
Samples: 4

Max nTPM: 104.8
Min nTPM: 70.0
Sample A Female 103.1
Sample B Female 73.7
Sample C Male 70.0
Sample D Male 104.8
Midbrain
nTPM: 90.7
Samples: 4

Max nTPM: 142.3
Min nTPM: 54.0
Sample A Female 142.3
Sample B Female 98.9
Sample C Male 54.0
Sample D Male 67.6
Periaqueductal gray
nTPM: 69.1
Samples: 3

Max nTPM: 79.1
Min nTPM: 54.7
Sample B Female 79.1
Sample C Male 54.7
Sample D Male 73.4
Superior colliculi
nTPM: 82.2
Samples: 4

Max nTPM: 97.5
Min nTPM: 68.3
Sample A Female 97.5
Sample B Female 68.3
Sample C Male 75.7
Sample D Male 87.2

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

115.3
Mouse sample Sample description nTPM
Midbrain
nTPM: 115.4
Samples: 4

Max nTPM: 120.7
Min nTPM: 111.3
Sample A Male 115.9
Sample B Male 113.5
Sample C Female 111.3
Sample D Female 120.7

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

1.8
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 1.8
71656904 Antisense, RP_050927_04_E05, Mouse strain C57BL/6J (56 days, male) 1.8

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