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TISSUE PRIMARY DATA MIDBRAIN Show tissue menu
ADIPOSE TISSUE ADRENAL GLAND AMYGDALA APPENDIX BASAL GANGLIA BONE MARROW BREAST BRONCHUS CEREBELLUM CEREBRAL CORTEX CERVIX CHOROID PLEXUS COLON DUODENUM
ENDOMETRIUM EPIDIDYMIS ESOPHAGUS FALLOPIAN TUBE GALLBLADDER HEART MUSCLE HIPPOCAMPAL FORMATION HYPOTHALAMUS KIDNEY LIVER LUNG LYMPH NODE MIDBRAIN NASOPHARYNX
ORAL MUCOSA OVARY PANCREAS PARATHYROID GLAND PITUITARY GLAND PLACENTA PROSTATE RECTUM RETINA SALIVARY GLAND SEMINAL VESICLE SKELETAL MUSCLE SKIN SMALL INTESTINE
SMOOTH MUSCLE SOFT TISSUE SPINAL CORD SPLEEN STOMACH TESTIS THYMUS THYROID GLAND TONGUE TONSIL URINARY BLADDER VAGINA
ANTIBODIES
AND
VALIDATION
Dictionary
Tissue proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:632.6 nTPM
HPA Brain:284.8 nTPM
GTEx:632.6 nTPM
FANTOM5:284.5 Scaled Tags Per Million
Pig:240.5 nTPM
Mouse:427.4 nTPM
Allen mouse:7.5 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

284.8
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 261.5
2586 Male, age 75, left hemisphere 390.7
2666 Male, age 74, left hemisphere 287.8
2411 Female, age 72, unknown 287.6
1870 Female, age 42, unknown 260.3
1827 Male, age 72, unknown 250.8
2828 Female, age 72, unknown 248.2
1833 Male, age 53, unknown 235.1
1830 Male, age 51, unknown 225.3
2019 Male, age 18, unknown 220.2
2219 Male, age 76, both hemispheres 209.1
Dorsal raphe nucleus
nTPM: 266.1
2298 Female, age 72, unknown 280.0
2016 Female, age 72, unknown 272.7
2750 Male, age 76, both hemispheres 263.7
2047 Male, age 72, unknown 262.4
1828 Male, age 53, unknown 251.7
Inferior colliculus
nTPM: 227.1
1890 Male, age 53, unknown 243.4
2097 Female, age 72, unknown 235.8
1848 Female, age 42, unknown 222.1
2849 Male, age 72, unknown 207.1
Median raphe nucleus
nTPM: 219.9
2220 Male, age 76, midline 219.9
Periaquaductal grey, anterior
nTPM: 284.8
2502 Female, age 75, unknown 337.2
1947 Male, age 18, unknown 262.7
1795 Male, age 51, unknown 254.5
Periaquaductal grey, dorsal
nTPM: 227.5
1840 Male, age 53, unknown 251.4
2464 Female, age 72, unknown 239.4
1831 Male, age 72, unknown 238.0
2850 Male, age 76, both hemispheres 181.1
Periaquaductal grey, lateral
nTPM: 209.9
2053 Male, age 18, unknown 260.6
2140 Male, age 76, both hemispheres 189.0
2272 Male, age 74, both hemispheres 180.2
Pretectal area
nTPM: 220.2
2825 Male, age 18, unknown 239.9
2007 Male, age 72, unknown 239.1
2407 Male, age 75, both hemispheres 237.2
2316 Male, age 76, right hemisphere 236.3
2224 Female, age 72, unknown 227.6
1815 Male, age 53, unknown 227.4
1817 Female, age 42, unknown 224.7
1816 Male, age 51, unknown 220.7
2273 Male, age 74, both hemispheres 193.1
1944 Female, age 72, unknown 189.4
2667 Female, age 75, unknown 186.7
Red nucleus
nTPM: 270.6
2503 Female, age 72, unknown 325.8
2584 Male, age 75, left hemisphere 309.6
1821 Female, age 72, unknown 293.0
1904 Male, age 53, unknown 285.5
2588 Male, age 74, left hemisphere 284.2
2769 Male, age 72, unknown 284.0
1865 Male, age 51, unknown 278.7
2227 Male, age 72, unknown 276.9
2785 Male, age 18, unknown 245.9
2725 Female, age 75, unknown 243.2
1954 Female, age 42, unknown 223.4
2823 Male, age 76, right hemisphere 197.5
Substantia nigra
nTPM: 272.5
1851 Male, age 51, unknown 337.8
2665 Male, age 74, both hemispheres 302.8
2699 Male, age 18, unknown 295.5
2590 Female, age 75, unknown 290.3
1916 Female, age 42, unknown 283.1
2583 Male, age 75, right hemisphere 263.5
1889 Female, age 72, unknown 248.0
1941 Male, age 53, unknown 237.8
2241 Male, age 72, unknown 235.5
2409 Female, age 72, unknown 230.4
Superior colliculus
nTPM: 257.7
2664 Male, age 75, both hemispheres 325.3
2587 Male, age 74, left hemisphere 298.3
1995 Male, age 72, unknown 266.1
2668 Female, age 75, unknown 258.3
1796 Male, age 53, unknown 257.2
1839 Male, age 51, unknown 256.9
1913 Female, age 42, unknown 254.0
2261 Male, age 18, unknown 233.2
1895 Male, age 76, right hemisphere 215.9
2087 Female, age 72, unknown 211.4
Ventral tegmental area
nTPM: 265.5
2410 Female, age 72, unknown 301.5
1915 Female, age 42, unknown 293.4
2223 Female, age 72, unknown 269.5
2021 Male, age 53, unknown 261.4
1942 Male, age 51, unknown 254.9
2218 Male, age 76, both hemispheres 212.1

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

632.6
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 632.6
Samples: 139

Max nTPM: 1853.0
Min nTPM: 289.3
Std nTPM: 232.8
Median nTPM: 581.4
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 1853.0
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 1390.4
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 1289.6
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 1286.3
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 1197.0
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 1143.3
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 1099.5
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 1076.8
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 1056.5
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 1043.9
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 937.8
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 930.4
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 924.9
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 915.5
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 913.3
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 902.9
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 880.5
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 870.3
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 864.2
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 847.5
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 838.4
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 816.0
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 814.3
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 813.1
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 803.4
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 794.2
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 758.2
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 758.0
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 756.6
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 732.2
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 724.6
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 721.1
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 717.8
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 715.3
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 713.7
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 710.6
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 704.7
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 704.1
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 699.2
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 691.0
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 688.1
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 686.3
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 679.1
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 677.9
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 676.5
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 668.7
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 664.6
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 661.8
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 659.5
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 655.1
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 654.5
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 653.3
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 652.9
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 647.3
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 642.9
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 638.0
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 637.8
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 631.4
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 619.2
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 617.6
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 616.1
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 614.2
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 613.4
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 607.6
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 604.7
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 600.3
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 597.2
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 595.2
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 587.1
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 581.4
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 577.6
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 574.6
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 574.4
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 565.3
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 564.8
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 558.8
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 556.6
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 556.4
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 555.7
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 555.2
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 549.9
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 546.9
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 545.8
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 544.9
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 537.6
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 534.4
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 532.6
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 527.3
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 523.8
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 523.7
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 521.9
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 515.6
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 514.0
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 510.4
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 509.8
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 507.5
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 507.2
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 505.2
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 504.2
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 500.6
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 499.9
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 496.6
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 493.9
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 492.2
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 482.3
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 476.2
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 472.6
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 469.7
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 468.6
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 458.9
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 457.2
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 456.2
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 454.3
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 442.0
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 438.8
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 436.6
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 434.2
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 434.1
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 432.4
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 429.0
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 421.6
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 421.2
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 411.5
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 409.8
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 408.4
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 391.1
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 388.9
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 385.1
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 383.2
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 378.1
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 370.0
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 369.8
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 361.9
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 358.8
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 357.3
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 331.3
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 320.3
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 304.1
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 289.3
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MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

284.5
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 284.5
FF:10158-103A5 76 years, female 284.5

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

240.5
Pig sample Sample description nTPM
Substantia nigra
nTPM: 235.2
Samples: 4

Max nTPM: 291.0
Min nTPM: 180.7
Sample A Female 291.0
Sample B Female 243.5
Sample C Male 180.7
Sample D Male 225.7
Midbrain
nTPM: 231.6
Samples: 4

Max nTPM: 349.5
Min nTPM: 161.1
Sample A Female 349.5
Sample B Female 234.1
Sample C Male 181.8
Sample D Male 161.1
Periaqueductal gray
nTPM: 175.7
Samples: 3

Max nTPM: 182.9
Min nTPM: 166.4
Sample B Female 182.9
Sample C Male 177.7
Sample D Male 166.4
Superior colliculi
nTPM: 240.5
Samples: 4

Max nTPM: 283.7
Min nTPM: 189.6
Sample A Female 283.7
Sample B Female 274.1
Sample C Male 189.6
Sample D Male 214.6

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

427.4
Mouse sample Sample description nTPM
Midbrain
nTPM: 427.5
Samples: 4

Max nTPM: 486.7
Min nTPM: 382.9
Sample A Male 486.7
Sample B Male 414.3
Sample C Female 382.9
Sample D Female 425.9

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

7.5
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 7.5
77464982 Antisense, RP_070129_02_F08, Mouse strain C57BL/6J (56 days, male) 7.5
77868800 Antisense, RP_070129_02_F08, Mouse strain C57BL/6J (56 days, male) 2.3

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The Human Protein Atlas

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The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg Foundation.


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