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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:106.8 nTPM
HPA Brain:109.6 nTPM
GTEx:106.8 nTPM
FANTOM5:213.7 Scaled Tags Per Million
Pig:83.0 nTPM
Mouse:114.0 nTPM
Allen mouse:9.9 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

109.6
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 107.8
2828 Female, age 72, unknown 122.1
2411 Female, age 72, unknown 118.6
1827 Male, age 72, unknown 117.9
2586 Male, age 75, left hemisphere 113.5
1870 Female, age 42, unknown 107.9
1833 Male, age 53, unknown 107.4
2019 Male, age 18, unknown 103.4
2666 Male, age 74, left hemisphere 99.3
1830 Male, age 51, unknown 97.2
2219 Male, age 76, both hemispheres 90.4
Dorsal raphe nucleus
nTPM: 108.5
2298 Female, age 72, unknown 126.3
2016 Female, age 72, unknown 109.7
2047 Male, age 72, unknown 106.2
2750 Male, age 76, both hemispheres 100.9
1828 Male, age 53, unknown 99.4
Inferior colliculus
nTPM: 98.0
2849 Male, age 72, unknown 108.1
1848 Female, age 42, unknown 102.3
2097 Female, age 72, unknown 91.4
1890 Male, age 53, unknown 90.3
Median raphe nucleus
nTPM: 97.7
2220 Male, age 76, midline 97.7
Periaquaductal grey, anterior
nTPM: 106.3
1947 Male, age 18, unknown 111.8
1795 Male, age 51, unknown 105.4
2502 Female, age 75, unknown 101.7
Periaquaductal grey, dorsal
nTPM: 104.6
2850 Male, age 76, both hemispheres 111.8
1840 Male, age 53, unknown 109.0
1831 Male, age 72, unknown 99.3
2464 Female, age 72, unknown 98.5
Periaquaductal grey, lateral
nTPM: 105.5
2272 Male, age 74, both hemispheres 113.1
2053 Male, age 18, unknown 103.0
2140 Male, age 76, both hemispheres 100.4
Pretectal area
nTPM: 109.6
1816 Male, age 51, unknown 122.8
2007 Male, age 72, unknown 120.6
1817 Female, age 42, unknown 118.7
1815 Male, age 53, unknown 114.7
2316 Male, age 76, right hemisphere 113.7
2667 Female, age 75, unknown 112.7
2273 Male, age 74, both hemispheres 108.3
2825 Male, age 18, unknown 106.0
2224 Female, age 72, unknown 101.7
1944 Female, age 72, unknown 99.9
2407 Male, age 75, both hemispheres 86.8
Red nucleus
nTPM: 108.1
1821 Female, age 72, unknown 114.2
2725 Female, age 75, unknown 113.2
2588 Male, age 74, left hemisphere 113.0
2823 Male, age 76, right hemisphere 112.7
2503 Female, age 72, unknown 111.9
1904 Male, age 53, unknown 111.1
1954 Female, age 42, unknown 107.8
1865 Male, age 51, unknown 107.0
2785 Male, age 18, unknown 106.9
2227 Male, age 72, unknown 102.9
2769 Male, age 72, unknown 102.5
2584 Male, age 75, left hemisphere 94.3
Substantia nigra
nTPM: 104.7
1851 Male, age 51, unknown 114.4
2665 Male, age 74, both hemispheres 112.3
2590 Female, age 75, unknown 110.9
2583 Male, age 75, right hemisphere 109.1
1916 Female, age 42, unknown 108.5
1941 Male, age 53, unknown 108.0
1889 Female, age 72, unknown 105.9
2699 Male, age 18, unknown 101.7
2409 Female, age 72, unknown 91.5
2241 Male, age 72, unknown 85.2
Superior colliculus
nTPM: 107.6
2587 Male, age 74, left hemisphere 121.8
1913 Female, age 42, unknown 117.1
1995 Male, age 72, unknown 115.6
2261 Male, age 18, unknown 115.2
1796 Male, age 53, unknown 110.4
1895 Male, age 76, right hemisphere 105.4
1839 Male, age 51, unknown 102.3
2668 Female, age 75, unknown 97.3
2087 Female, age 72, unknown 95.6
2664 Male, age 75, both hemispheres 95.0
Ventral tegmental area
nTPM: 102.3
2410 Female, age 72, unknown 120.8
1915 Female, age 42, unknown 106.1
2021 Male, age 53, unknown 99.8
1942 Male, age 51, unknown 97.2
2218 Male, age 76, both hemispheres 95.6
2223 Female, age 72, unknown 94.2

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

106.8
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 106.8
Samples: 139

Max nTPM: 193.4
Min nTPM: 77.3
Std nTPM: 21.6
Median nTPM: 101.5
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 193.4
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 187.3
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 175.8
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 166.3
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 166.0
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 163.3
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 159.7
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 153.3
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 152.3
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 151.6
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 142.0
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 136.6
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 133.5
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 130.5
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 128.8
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 128.0
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 127.1
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 126.8
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 125.9
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 125.2
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 122.4
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 122.3
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 122.3
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 122.3
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 122.2
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 121.9
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 120.5
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 120.3
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 119.6
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 119.2
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 119.1
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 119.0
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 117.9
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 115.0
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 114.2
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 113.5
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 113.5
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 112.9
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 111.7
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 111.6
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 110.3
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 110.2
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 110.0
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 109.7
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 108.5
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 108.4
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 108.3
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 107.2
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 106.9
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 106.6
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 105.9
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 105.7
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 105.4
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 104.7
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 104.4
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 104.2
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 104.0
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 103.9
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 103.8
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 103.6
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 103.5
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 103.4
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 103.3
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 103.1
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 102.8
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 102.7
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 102.6
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 102.5
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 102.0
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 101.5
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 101.4
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 101.3
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 101.1
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 100.6
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 100.3
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 100.2
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 100.1
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 99.8
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 99.3
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 98.8
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 98.8
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 98.7
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 98.4
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 98.2
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 97.5
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 97.3
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 96.8
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 96.6
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 96.4
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 96.4
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 96.4
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 96.3
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 96.2
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 95.9
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 95.9
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 95.9
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 95.8
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 95.8
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 95.7
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 95.6
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 95.5
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 95.4
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 94.4
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 93.8
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 92.9
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 92.7
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 92.5
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 92.3
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 92.2
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 92.2
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 91.6
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 91.3
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 90.2
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 89.8
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 89.4
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 89.4
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 89.2
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 88.2
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 88.2
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 88.0
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 87.5
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 87.5
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 87.4
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 87.2
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 87.1
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 86.6
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 86.3
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 84.8
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 83.2
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 82.7
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 82.2
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 82.1
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 81.8
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 80.9
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 80.6
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 80.3
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 79.7
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 78.0
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 77.3
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

213.7
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 213.7
FF:10158-103A5 76 years, female 213.7

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

83.0
Pig sample Sample description nTPM
Substantia nigra
nTPM: 74.5
Samples: 4

Max nTPM: 78.2
Min nTPM: 67.5
Sample A Female 78.2
Sample B Female 67.5
Sample C Male 76.5
Sample D Male 75.7
Midbrain
nTPM: 83.0
Samples: 4

Max nTPM: 110.5
Min nTPM: 69.1
Sample A Female 110.5
Sample B Female 69.1
Sample C Male 82.3
Sample D Male 70.2
Periaqueductal gray
nTPM: 74.3
Samples: 3

Max nTPM: 80.9
Min nTPM: 68.3
Sample B Female 73.8
Sample C Male 80.9
Sample D Male 68.3
Superior colliculi
nTPM: 82.8
Samples: 4

Max nTPM: 89.5
Min nTPM: 78.4
Sample A Female 89.5
Sample B Female 79.4
Sample C Male 83.9
Sample D Male 78.4

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

114.0
Mouse sample Sample description nTPM
Midbrain
nTPM: 114.0
Samples: 4

Max nTPM: 116.7
Min nTPM: 108.7
Sample A Male 116.3
Sample B Male 108.7
Sample C Female 114.4
Sample D Female 116.7

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

9.9
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 9.9
74988735 Antisense, RP_060315_04_B03, Mouse strain C57BL/6J (56 days, male) 11.4
70593345 Antisense, RP_050407_04_A05, Mouse strain C57BL/6J (56 days, male) 8.4

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