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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:631.2 nTPM
HPA Brain:359.8 nTPM
GTEx:631.2 nTPM
FANTOM5:556.5 Scaled Tags Per Million
Pig:204.5 nTPM
Mouse:155.9 nTPM
Allen mouse:8.8 Expression energy

MIDBRAIN - Annotated protein expression
Pending normal tissue analysis

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

359.8
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 258.4
2411 Female, age 72, unknown 362.1
1870 Female, age 42, unknown 340.6
1833 Male, age 53, unknown 295.0
1827 Male, age 72, unknown 284.1
1830 Male, age 51, unknown 269.6
2019 Male, age 18, unknown 235.9
2219 Male, age 76, both hemispheres 230.0
2828 Female, age 72, unknown 229.0
2586 Male, age 75, left hemisphere 175.1
2666 Male, age 74, left hemisphere 162.2
Dorsal raphe nucleus
nTPM: 358.2
2298 Female, age 72, unknown 484.8
2047 Male, age 72, unknown 376.5
2750 Male, age 76, both hemispheres 320.7
1828 Male, age 53, unknown 306.1
2016 Female, age 72, unknown 302.8
Inferior colliculus
nTPM: 290.1
2097 Female, age 72, unknown 316.8
2849 Male, age 72, unknown 307.7
1848 Female, age 42, unknown 289.1
1890 Male, age 53, unknown 246.8
Median raphe nucleus
nTPM: 346.2
2220 Male, age 76, midline 346.2
Periaquaductal grey, anterior
nTPM: 288.0
1947 Male, age 18, unknown 316.5
1795 Male, age 51, unknown 278.0
2502 Female, age 75, unknown 269.5
Periaquaductal grey, dorsal
nTPM: 318.1
2850 Male, age 76, both hemispheres 388.3
1840 Male, age 53, unknown 351.8
2464 Female, age 72, unknown 278.1
1831 Male, age 72, unknown 254.1
Periaquaductal grey, lateral
nTPM: 359.8
2272 Male, age 74, both hemispheres 436.7
2140 Male, age 76, both hemispheres 326.2
2053 Male, age 18, unknown 316.6
Pretectal area
nTPM: 300.9
2273 Male, age 74, both hemispheres 469.1
2224 Female, age 72, unknown 367.0
2667 Female, age 75, unknown 315.7
2825 Male, age 18, unknown 315.4
1817 Female, age 42, unknown 276.2
1944 Female, age 72, unknown 274.8
1815 Male, age 53, unknown 271.4
1816 Male, age 51, unknown 263.2
2007 Male, age 72, unknown 261.3
2407 Male, age 75, both hemispheres 252.2
2316 Male, age 76, right hemisphere 243.6
Red nucleus
nTPM: 251.8
1821 Female, age 72, unknown 334.1
2725 Female, age 75, unknown 292.6
1954 Female, age 42, unknown 269.3
1865 Male, age 51, unknown 262.5
2503 Female, age 72, unknown 255.7
1904 Male, age 53, unknown 253.2
2227 Male, age 72, unknown 248.9
2769 Male, age 72, unknown 247.5
2823 Male, age 76, right hemisphere 241.9
2785 Male, age 18, unknown 238.3
2584 Male, age 75, left hemisphere 189.8
2588 Male, age 74, left hemisphere 188.2
Substantia nigra
nTPM: 278.2
1916 Female, age 42, unknown 335.0
1941 Male, age 53, unknown 329.1
2241 Male, age 72, unknown 322.3
1889 Female, age 72, unknown 316.9
1851 Male, age 51, unknown 312.7
2699 Male, age 18, unknown 286.6
2409 Female, age 72, unknown 256.4
2590 Female, age 75, unknown 237.2
2583 Male, age 75, right hemisphere 199.2
2665 Male, age 74, both hemispheres 186.7
Superior colliculus
nTPM: 270.2
2587 Male, age 74, left hemisphere 360.0
1895 Male, age 76, right hemisphere 291.3
1796 Male, age 53, unknown 284.3
1913 Female, age 42, unknown 275.1
1839 Male, age 51, unknown 274.5
2261 Male, age 18, unknown 270.4
2668 Female, age 75, unknown 261.2
1995 Male, age 72, unknown 246.4
2087 Female, age 72, unknown 230.0
2664 Male, age 75, both hemispheres 209.1
Ventral tegmental area
nTPM: 306.9
2410 Female, age 72, unknown 350.7
2223 Female, age 72, unknown 341.1
2218 Male, age 76, both hemispheres 312.1
1915 Female, age 42, unknown 311.9
1942 Male, age 51, unknown 265.6
2021 Male, age 53, unknown 259.8

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

631.2
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 631.2
Samples: 139

Max nTPM: 1609.5
Min nTPM: 250.9
Std nTPM: 207.2
Median nTPM: 585.8
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 1609.5
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 1432.2
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 1389.2
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 1292.5
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 1249.3
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 1200.7
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 1090.4
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 1038.4
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 1015.2
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 887.4
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 870.7
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 864.0
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 863.7
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 841.6
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 837.5
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 828.6
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 814.9
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 782.3
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 776.0
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 771.0
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 769.5
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 757.4
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 745.8
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 745.1
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 743.2
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 734.1
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 732.3
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 725.5
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 719.0
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 708.8
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 702.7
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 697.1
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 695.3
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 684.3
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 681.6
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 681.0
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 676.3
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 664.5
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 658.0
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 655.5
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 653.5
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 652.5
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 650.1
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 647.3
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 646.8
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 645.9
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 644.7
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 637.4
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 633.9
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 627.8
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 624.7
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 622.5
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 622.5
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 621.4
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 619.3
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 618.4
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 614.0
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 612.8
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 610.1
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 609.3
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 606.3
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 606.3
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 605.2
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 599.7
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 596.8
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 592.9
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 591.9
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 591.0
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 586.9
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 585.8
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 584.3
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 582.3
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 580.5
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 579.4
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 579.3
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 575.9
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 575.5
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 572.7
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 571.7
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 569.9
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 568.1
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 567.7
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 561.9
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 561.1
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 559.2
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 559.2
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 559.1
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 558.1
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 556.8
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 554.7
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 553.6
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 552.5
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 552.1
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 539.4
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 539.1
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 538.7
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 534.6
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 533.5
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 533.2
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 532.5
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 529.8
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 528.1
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 526.8
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 525.5
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 522.2
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 522.1
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 516.0
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 507.5
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 504.7
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 497.9
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 492.2
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 490.9
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 490.1
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 487.3
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 479.7
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 477.3
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 474.8
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 470.7
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 469.5
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 462.9
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 462.5
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 460.9
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 459.4
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 455.9
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 451.0
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 438.5
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 437.5
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 437.3
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 425.6
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 419.9
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 412.1
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 403.1
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 401.5
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 400.5
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 373.1
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 365.9
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 360.9
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 346.5
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 250.9
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

556.5
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 556.5
FF:10158-103A5 76 years, female 556.5

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

204.5
Pig sample Sample description nTPM
Substantia nigra
nTPM: 195.9
Samples: 4

Max nTPM: 245.8
Min nTPM: 163.3
Sample A Female 245.8
Sample B Female 163.3
Sample C Male 176.7
Sample D Male 197.6
Midbrain
nTPM: 204.5
Samples: 4

Max nTPM: 322.8
Min nTPM: 155.3
Sample A Female 322.8
Sample B Female 175.4
Sample C Male 155.3
Sample D Male 164.3
Periaqueductal gray
nTPM: 183.0
Samples: 3

Max nTPM: 205.1
Min nTPM: 157.6
Sample B Female 157.6
Sample C Male 186.2
Sample D Male 205.1
Superior colliculi
nTPM: 187.9
Samples: 4

Max nTPM: 227.4
Min nTPM: 155.1
Sample A Female 227.4
Sample B Female 155.1
Sample C Male 183.7
Sample D Male 185.5

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

155.9
Mouse sample Sample description nTPM
Midbrain
nTPM: 155.9
Samples: 4

Max nTPM: 162.0
Min nTPM: 148.5
Sample A Male 154.0
Sample B Male 159.2
Sample C Female 148.5
Sample D Female 162.0

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

8.8
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 8.8
69627021 Antisense, RP_050428_01_G02, Mouse strain C57BL/6J (56 days, male) 9.8
81600140 Antisense, RP_080312_03_A05, Mouse strain C57BL/6J (56 days, male) 7.9

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