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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:576.3 nTPM
HPA Brain:854.0 nTPM
GTEx:576.3 nTPM
FANTOM5:1958.7 Scaled Tags Per Million
Pig:583.2 nTPM
Mouse:1161.1 nTPM
Allen mouse:23.0 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

854.0
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 622.1
2666 Male, age 74, left hemisphere 746.1
2411 Female, age 72, unknown 744.8
1827 Male, age 72, unknown 736.1
2219 Male, age 76, both hemispheres 664.9
2019 Male, age 18, unknown 594.0
1870 Female, age 42, unknown 592.2
1833 Male, age 53, unknown 578.2
2828 Female, age 72, unknown 565.7
1830 Male, age 51, unknown 513.1
2586 Male, age 75, left hemisphere 485.3
Dorsal raphe nucleus
nTPM: 737.1
2298 Female, age 72, unknown 913.5
2047 Male, age 72, unknown 841.2
1828 Male, age 53, unknown 713.4
2750 Male, age 76, both hemispheres 663.6
2016 Female, age 72, unknown 553.7
Inferior colliculus
nTPM: 564.5
2097 Female, age 72, unknown 625.0
2849 Male, age 72, unknown 552.0
1848 Female, age 42, unknown 544.8
1890 Male, age 53, unknown 536.2
Median raphe nucleus
nTPM: 854.0
2220 Male, age 76, midline 854.0
Periaquaductal grey, anterior
nTPM: 704.7
1947 Male, age 18, unknown 805.9
1795 Male, age 51, unknown 673.9
2502 Female, age 75, unknown 634.3
Periaquaductal grey, dorsal
nTPM: 594.7
1840 Male, age 53, unknown 652.9
2850 Male, age 76, both hemispheres 624.2
2464 Female, age 72, unknown 558.9
1831 Male, age 72, unknown 542.9
Periaquaductal grey, lateral
nTPM: 577.6
2272 Male, age 74, both hemispheres 627.5
2053 Male, age 18, unknown 562.6
2140 Male, age 76, both hemispheres 542.8
Pretectal area
nTPM: 679.3
1816 Male, age 51, unknown 875.4
1944 Female, age 72, unknown 767.4
2007 Male, age 72, unknown 767.3
1817 Female, age 42, unknown 746.6
2224 Female, age 72, unknown 722.7
1815 Male, age 53, unknown 689.6
2667 Female, age 75, unknown 686.5
2825 Male, age 18, unknown 612.2
2273 Male, age 74, both hemispheres 580.8
2407 Male, age 75, both hemispheres 549.1
2316 Male, age 76, right hemisphere 474.6
Red nucleus
nTPM: 586.0
1821 Female, age 72, unknown 750.5
2725 Female, age 75, unknown 713.7
2588 Male, age 74, left hemisphere 622.1
2503 Female, age 72, unknown 605.2
2584 Male, age 75, left hemisphere 582.1
1954 Female, age 42, unknown 567.5
1904 Male, age 53, unknown 553.6
1865 Male, age 51, unknown 547.6
2785 Male, age 18, unknown 545.1
2227 Male, age 72, unknown 522.8
2769 Male, age 72, unknown 520.4
2823 Male, age 76, right hemisphere 501.7
Substantia nigra
nTPM: 845.5
1916 Female, age 42, unknown 1201.1
1851 Male, age 51, unknown 980.9
2241 Male, age 72, unknown 973.3
1941 Male, age 53, unknown 938.3
1889 Female, age 72, unknown 795.4
2409 Female, age 72, unknown 783.7
2699 Male, age 18, unknown 774.8
2665 Male, age 74, both hemispheres 759.6
2590 Female, age 75, unknown 659.3
2583 Male, age 75, right hemisphere 588.3
Superior colliculus
nTPM: 579.2
2087 Female, age 72, unknown 668.4
2261 Male, age 18, unknown 661.3
1796 Male, age 53, unknown 660.7
2587 Male, age 74, left hemisphere 642.4
2668 Female, age 75, unknown 633.4
1839 Male, age 51, unknown 564.5
1895 Male, age 76, right hemisphere 542.8
2664 Male, age 75, both hemispheres 509.7
1913 Female, age 42, unknown 482.4
1995 Male, age 72, unknown 426.1
Ventral tegmental area
nTPM: 762.1
2410 Female, age 72, unknown 939.9
1915 Female, age 42, unknown 888.3
2218 Male, age 76, both hemispheres 823.8
2223 Female, age 72, unknown 659.4
1942 Male, age 51, unknown 653.9
2021 Male, age 53, unknown 607.6

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

576.3
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 576.3
Samples: 139

Max nTPM: 2060.0
Min nTPM: 246.6
Std nTPM: 270.9
Median nTPM: 494.5
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 2060.0
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 1875.9
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 1282.1
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 1204.6
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 1182.8
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 1169.0
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 1125.7
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 1114.1
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 1006.9
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 994.1
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 992.5
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 936.6
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 912.8
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 898.4
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 893.9
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 884.0
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 859.4
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 844.8
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 844.3
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 797.0
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 768.2
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 765.9
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 761.1
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 755.1
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 750.3
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 748.7
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 740.2
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 732.3
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 730.8
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 707.3
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 678.2
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 677.0
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 668.0
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 665.3
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 660.7
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 658.5
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 651.4
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 644.1
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 641.2
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 620.1
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 618.9
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 609.9
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 607.4
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 596.2
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 586.4
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 585.5
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 584.0
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 580.0
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 575.9
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 575.8
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 572.6
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 569.2
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 565.4
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 562.8
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 558.7
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 557.2
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 552.0
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 519.8
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 517.8
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 517.4
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 512.3
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 510.6
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 508.5
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 507.5
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 503.6
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 500.2
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 497.3
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 497.3
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 494.7
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 494.5
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 494.2
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 492.1
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 491.8
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 489.0
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 487.1
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 487.0
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 484.4
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 483.8
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 483.5
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 479.6
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 473.0
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 472.8
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 468.2
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 462.9
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 461.7
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 459.6
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 458.4
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 455.9
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 455.7
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 448.1
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 439.9
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 439.2
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 437.2
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 433.2
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 427.7
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 423.8
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 421.9
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 418.5
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 412.6
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 411.9
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 411.1
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 407.0
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 406.3
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 405.8
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 403.9
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 402.1
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 397.6
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 393.8
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 391.9
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 383.8
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 383.6
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 382.1
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 381.5
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 380.4
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 377.5
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 377.0
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 374.1
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 373.1
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 373.1
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 363.8
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 363.5
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 359.5
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 355.5
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 353.2
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 352.7
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 352.0
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 349.0
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 343.4
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 340.3
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 334.1
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 330.0
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 323.6
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 323.2
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 310.2
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 307.1
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 304.1
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 302.0
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 287.6
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 246.6
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

1958.7
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 1958.7
FF:10158-103A5 76 years, female 1958.7

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

583.2
Pig sample Sample description nTPM
Substantia nigra
nTPM: 583.2
Samples: 4

Max nTPM: 768.3
Min nTPM: 358.3
Sample A Female 750.4
Sample B Female 455.9
Sample C Male 768.3
Sample D Male 358.3
Midbrain
nTPM: 566.8
Samples: 4

Max nTPM: 701.1
Min nTPM: 512.3
Sample A Female 524.1
Sample B Female 512.3
Sample C Male 701.1
Sample D Male 529.8
Periaqueductal gray
nTPM: 477.3
Samples: 3

Max nTPM: 583.0
Min nTPM: 398.4
Sample B Female 450.4
Sample C Male 583.0
Sample D Male 398.4
Superior colliculi
nTPM: 538.2
Samples: 4

Max nTPM: 636.9
Min nTPM: 385.3
Sample A Female 599.5
Sample B Female 385.3
Sample C Male 636.9
Sample D Male 531.0

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

1161.1
Mouse sample Sample description nTPM
Midbrain
nTPM: 1161.1
Samples: 4

Max nTPM: 1207.0
Min nTPM: 1098.4
Sample A Male 1098.4
Sample B Male 1166.7
Sample C Female 1207.0
Sample D Female 1172.4

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

23.0
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 23.0
69735168 Antisense, RP_050503_02_C01, Mouse strain C57BL/6J (56 days, male) 23.0

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