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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:717.3 nTPM
HPA Brain:720.9 nTPM
GTEx:717.3 nTPM
FANTOM5:762.6 Scaled Tags Per Million
Pig:710.1 nTPM
Mouse:616.2 nTPM
Allen mouse:12.1 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

720.9
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 576.7
2586 Male, age 75, left hemisphere 776.8
2828 Female, age 72, unknown 748.0
2666 Male, age 74, left hemisphere 586.0
2411 Female, age 72, unknown 583.3
1827 Male, age 72, unknown 565.2
1870 Female, age 42, unknown 561.5
2019 Male, age 18, unknown 532.8
1833 Male, age 53, unknown 527.9
1830 Male, age 51, unknown 498.9
2219 Male, age 76, both hemispheres 386.4
Dorsal raphe nucleus
nTPM: 715.4
2298 Female, age 72, unknown 881.5
2016 Female, age 72, unknown 823.5
1828 Male, age 53, unknown 649.3
2047 Male, age 72, unknown 630.5
2750 Male, age 76, both hemispheres 592.2
Inferior colliculus
nTPM: 563.4
2097 Female, age 72, unknown 638.1
1890 Male, age 53, unknown 565.2
1848 Female, age 42, unknown 552.6
2849 Male, age 72, unknown 497.6
Median raphe nucleus
nTPM: 462.3
2220 Male, age 76, midline 462.3
Periaquaductal grey, anterior
nTPM: 709.2
1795 Male, age 51, unknown 763.7
1947 Male, age 18, unknown 714.0
2502 Female, age 75, unknown 650.0
Periaquaductal grey, dorsal
nTPM: 664.6
2850 Male, age 76, both hemispheres 717.4
1840 Male, age 53, unknown 707.5
2464 Female, age 72, unknown 633.4
1831 Male, age 72, unknown 600.2
Periaquaductal grey, lateral
nTPM: 720.9
2140 Male, age 76, both hemispheres 798.9
2053 Male, age 18, unknown 686.8
2272 Male, age 74, both hemispheres 676.9
Pretectal area
nTPM: 626.3
2273 Male, age 74, both hemispheres 787.5
2316 Male, age 76, right hemisphere 679.6
2224 Female, age 72, unknown 674.2
2825 Male, age 18, unknown 634.6
1817 Female, age 42, unknown 631.0
2667 Female, age 75, unknown 627.1
1815 Male, age 53, unknown 610.7
1944 Female, age 72, unknown 599.5
1816 Male, age 51, unknown 574.7
2007 Male, age 72, unknown 570.6
2407 Male, age 75, both hemispheres 499.2
Red nucleus
nTPM: 593.9
2503 Female, age 72, unknown 701.1
2227 Male, age 72, unknown 677.2
2769 Male, age 72, unknown 655.2
1954 Female, age 42, unknown 624.0
1821 Female, age 72, unknown 610.9
1904 Male, age 53, unknown 607.6
2725 Female, age 75, unknown 601.1
1865 Male, age 51, unknown 598.9
2785 Male, age 18, unknown 565.3
2823 Male, age 76, right hemisphere 530.8
2588 Male, age 74, left hemisphere 511.2
2584 Male, age 75, left hemisphere 443.8
Substantia nigra
nTPM: 580.9
1916 Female, age 42, unknown 653.9
1851 Male, age 51, unknown 651.4
2590 Female, age 75, unknown 626.2
2699 Male, age 18, unknown 607.9
2665 Male, age 74, both hemispheres 581.2
2583 Male, age 75, right hemisphere 572.5
1889 Female, age 72, unknown 564.3
2241 Male, age 72, unknown 531.6
2409 Female, age 72, unknown 511.5
1941 Male, age 53, unknown 508.6
Superior colliculus
nTPM: 614.1
1995 Male, age 72, unknown 790.5
1796 Male, age 53, unknown 675.2
2261 Male, age 18, unknown 652.4
2087 Female, age 72, unknown 641.1
2664 Male, age 75, both hemispheres 627.3
1913 Female, age 42, unknown 612.2
2668 Female, age 75, unknown 594.7
2587 Male, age 74, left hemisphere 580.0
1839 Male, age 51, unknown 544.7
1895 Male, age 76, right hemisphere 422.6
Ventral tegmental area
nTPM: 616.1
1942 Male, age 51, unknown 681.4
2021 Male, age 53, unknown 674.0
2410 Female, age 72, unknown 648.9
1915 Female, age 42, unknown 623.0
2218 Male, age 76, both hemispheres 546.8
2223 Female, age 72, unknown 522.6

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

717.3
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 717.3
Samples: 139

Max nTPM: 1753.0
Min nTPM: 259.1
Std nTPM: 279.1
Median nTPM: 667.1
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 1753.0
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 1719.4
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 1645.0
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 1640.8
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 1527.2
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 1490.2
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 1365.2
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 1194.3
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 1108.9
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 1083.1
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 1077.7
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 1063.9
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 1061.0
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 1049.6
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 1049.1
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 1048.3
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 990.2
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 970.2
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 953.6
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 949.7
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 944.1
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 933.4
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 933.2
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 914.1
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 907.0
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 903.3
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 901.4
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 900.6
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 882.5
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 862.4
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 857.7
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 856.2
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 829.7
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 826.8
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 823.4
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 822.7
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 822.4
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 821.3
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 815.8
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 809.9
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 802.9
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 792.9
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 788.3
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 780.6
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 778.3
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 762.6
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 758.3
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 758.3
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 754.7
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 742.0
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 738.7
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 736.2
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 734.3
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 728.8
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 721.8
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 718.1
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 716.3
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 715.4
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 715.2
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 700.5
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 695.0
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 683.3
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 679.8
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 679.6
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 677.7
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 674.0
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 673.7
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 672.8
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 671.5
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 667.1
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 654.1
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 653.0
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 651.4
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 649.2
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 634.4
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 633.3
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 628.9
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 625.8
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 624.5
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 621.7
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 617.8
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 617.2
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 613.3
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 610.8
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 606.1
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 602.4
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 598.3
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 590.3
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 589.5
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 583.6
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 582.3
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 579.1
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 577.2
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 575.9
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 570.3
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 566.8
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 565.6
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 565.5
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 562.4
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 562.0
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 561.2
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 555.4
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 550.6
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 550.4
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 543.8
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 541.3
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 535.7
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 533.5
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 523.6
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 521.0
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 515.0
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 514.6
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 512.6
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 509.4
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 498.5
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 495.2
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 493.4
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 491.9
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 484.6
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 477.0
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 476.1
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 464.7
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 464.6
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 460.4
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 456.9
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 447.6
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 446.8
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 417.8
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 400.0
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 387.3
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 383.5
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 371.8
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 362.0
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 335.0
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 319.4
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 316.9
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 301.3
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 278.6
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 259.1
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

762.6
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 762.6
FF:10158-103A5 76 years, female 762.6

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

710.1
Pig sample Sample description nTPM
Substantia nigra
nTPM: 710.1
Samples: 4

Max nTPM: 805.9
Min nTPM: 566.8
Sample A Female 787.1
Sample B Female 566.8
Sample C Male 680.7
Sample D Male 805.9
Midbrain
nTPM: 630.2
Samples: 4

Max nTPM: 1058.4
Min nTPM: 435.9
Sample A Female 1058.4
Sample B Female 541.2
Sample C Male 485.1
Sample D Male 435.9
Periaqueductal gray
nTPM: 592.4
Samples: 3

Max nTPM: 696.0
Min nTPM: 530.5
Sample B Female 550.8
Sample C Male 696.0
Sample D Male 530.5
Superior colliculi
nTPM: 527.4
Samples: 4

Max nTPM: 672.6
Min nTPM: 369.1
Sample A Female 672.6
Sample B Female 369.1
Sample C Male 497.2
Sample D Male 570.7

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

616.2
Mouse sample Sample description nTPM
Midbrain
nTPM: 616.2
Samples: 4

Max nTPM: 635.6
Min nTPM: 579.2
Sample A Male 628.8
Sample B Male 579.2
Sample C Female 621.3
Sample D Female 635.6

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

12.1
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 12.1
227 Antisense, RP_Baylor_102672, Mouse strain C57BL/6J (56 days, male) 12.1
68269526 Antisense, RP_041129_01_G04, Mouse strain C57BL/6J (56 days, male) 12.1
226 Antisense, RP_Baylor_102672, Mouse strain C57BL/6J (56 days, male) 9.0

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