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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:810.6 nTPM
HPA Brain:570.8 nTPM
GTEx:810.6 nTPM
FANTOM5:451.0 Scaled Tags Per Million
Mouse:1156.9 nTPM
Allen mouse:20.0 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

570.8
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 404.7
2019 Male, age 18, unknown 468.0
2411 Female, age 72, unknown 457.8
1827 Male, age 72, unknown 454.1
2828 Female, age 72, unknown 448.8
2219 Male, age 76, both hemispheres 405.0
1870 Female, age 42, unknown 403.7
1833 Male, age 53, unknown 400.3
1830 Male, age 51, unknown 340.5
2666 Male, age 74, left hemisphere 335.3
2586 Male, age 75, left hemisphere 334.0
Dorsal raphe nucleus
nTPM: 505.7
1828 Male, age 53, unknown 582.5
2047 Male, age 72, unknown 557.7
2298 Female, age 72, unknown 530.1
2016 Female, age 72, unknown 464.4
2750 Male, age 76, both hemispheres 393.9
Inferior colliculus
nTPM: 528.0
1890 Male, age 53, unknown 578.5
2097 Female, age 72, unknown 546.2
1848 Female, age 42, unknown 528.4
2849 Male, age 72, unknown 458.9
Median raphe nucleus
nTPM: 438.5
2220 Male, age 76, midline 438.5
Periaquaductal grey, anterior
nTPM: 379.7
1947 Male, age 18, unknown 401.1
2502 Female, age 75, unknown 374.7
1795 Male, age 51, unknown 363.3
Periaquaductal grey, dorsal
nTPM: 437.8
1840 Male, age 53, unknown 503.7
2850 Male, age 76, both hemispheres 426.6
2464 Female, age 72, unknown 422.3
1831 Male, age 72, unknown 398.5
Periaquaductal grey, lateral
nTPM: 387.5
2053 Male, age 18, unknown 402.0
2140 Male, age 76, both hemispheres 387.2
2272 Male, age 74, both hemispheres 373.3
Pretectal area
nTPM: 476.3
2667 Female, age 75, unknown 597.1
1817 Female, age 42, unknown 586.3
1944 Female, age 72, unknown 569.6
1816 Male, age 51, unknown 552.5
2007 Male, age 72, unknown 509.5
1815 Male, age 53, unknown 454.7
2273 Male, age 74, both hemispheres 451.8
2224 Female, age 72, unknown 421.7
2825 Male, age 18, unknown 384.4
2316 Male, age 76, right hemisphere 380.7
2407 Male, age 75, both hemispheres 331.0
Red nucleus
nTPM: 457.6
1821 Female, age 72, unknown 630.4
2503 Female, age 72, unknown 531.9
1954 Female, age 42, unknown 486.1
2823 Male, age 76, right hemisphere 482.2
2227 Male, age 72, unknown 444.5
2769 Male, age 72, unknown 444.5
1865 Male, age 51, unknown 444.4
2725 Female, age 75, unknown 442.6
2588 Male, age 74, left hemisphere 439.4
1904 Male, age 53, unknown 430.0
2785 Male, age 18, unknown 410.7
2584 Male, age 75, left hemisphere 304.3
Substantia nigra
nTPM: 570.8
1916 Female, age 42, unknown 803.3
2241 Male, age 72, unknown 661.9
1851 Male, age 51, unknown 635.7
2699 Male, age 18, unknown 603.9
1889 Female, age 72, unknown 588.9
2665 Male, age 74, both hemispheres 571.6
1941 Male, age 53, unknown 536.6
2409 Female, age 72, unknown 492.3
2590 Female, age 75, unknown 454.3
2583 Male, age 75, right hemisphere 359.2
Superior colliculus
nTPM: 408.0
2087 Female, age 72, unknown 503.6
1895 Male, age 76, right hemisphere 495.1
2587 Male, age 74, left hemisphere 454.2
1796 Male, age 53, unknown 408.2
2668 Female, age 75, unknown 402.1
1839 Male, age 51, unknown 401.9
2261 Male, age 18, unknown 391.2
2664 Male, age 75, both hemispheres 370.1
1913 Female, age 42, unknown 330.9
1995 Male, age 72, unknown 322.1
Ventral tegmental area
nTPM: 486.5
2410 Female, age 72, unknown 597.3
1915 Female, age 42, unknown 593.9
2218 Male, age 76, both hemispheres 528.3
1942 Male, age 51, unknown 446.8
2223 Female, age 72, unknown 392.0
2021 Male, age 53, unknown 361.0

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

810.6
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 810.6
Samples: 139

Max nTPM: 1732.1
Min nTPM: 321.0
Std nTPM: 254.0
Median nTPM: 777.0
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 1732.1
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 1597.1
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 1467.8
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 1370.6
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 1350.1
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 1340.0
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 1262.9
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 1245.4
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 1240.8
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 1209.6
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 1208.1
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 1179.1
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 1167.5
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 1155.3
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 1152.6
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 1141.2
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 1114.4
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 1091.0
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 1082.0
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 1068.4
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 1059.6
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 1057.2
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 1049.6
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 1047.1
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 1041.5
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 1040.9
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 1019.7
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 1019.5
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 1006.2
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 1003.1
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 999.9
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 994.4
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 972.7
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 965.2
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 962.1
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 959.5
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 924.4
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 913.7
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 911.2
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 910.7
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 910.4
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 885.5
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 883.4
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 882.1
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 881.3
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 880.2
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 875.0
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 866.8
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 865.5
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 858.3
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 853.8
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 853.7
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 850.9
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 846.3
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 840.1
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 837.0
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 835.5
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 835.0
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 829.9
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 824.1
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 817.9
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 810.5
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 803.9
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 803.0
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 802.5
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 795.0
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 788.6
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 788.2
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 778.5
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 777.0
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 774.1
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 771.9
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 765.5
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 757.2
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 756.5
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 754.7
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 749.4
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 747.4
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 747.3
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 742.2
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 736.2
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 735.6
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 730.3
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 728.9
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 726.3
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 722.6
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 721.3
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 716.3
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 701.9
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 700.8
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 697.8
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 692.5
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 689.7
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 683.0
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 678.6
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 677.5
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 675.9
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 670.3
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 670.1
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 669.8
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 667.2
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 659.9
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 657.1
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 655.9
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 647.2
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 643.1
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 637.2
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 634.9
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 626.5
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 623.8
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 620.2
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 618.6
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 614.7
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 600.8
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 591.7
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 587.5
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 583.9
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 582.0
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 547.4
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 544.8
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 537.9
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 519.5
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 506.5
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 505.0
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 503.8
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 503.0
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 490.4
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 480.1
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 471.9
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 449.7
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 443.2
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 442.7
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 437.1
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 430.7
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 423.1
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 389.4
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 359.7
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 333.9
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 321.0
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MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

451.0
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 451.0
FF:10158-103A5 76 years, female 451.0

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

1156.9
Mouse sample Sample description nTPM
Midbrain
nTPM: 1156.9
Samples: 4

Max nTPM: 1191.4
Min nTPM: 1113.6
Sample A Male 1191.4
Sample B Male 1156.3
Sample C Female 1113.6
Sample D Female 1166.2

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

20.0
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 20.0
74736213 Antisense, RP_060302_02_E08, Mouse strain C57BL/6J (56 days, male) 20.0

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