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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:1331.1 nTPM
HPA Brain:592.1 nTPM
GTEx:1331.1 nTPM
FANTOM5:533.2 Scaled Tags Per Million
Pig:125.5 nTPM
Mouse:356.9 nTPM
Allen mouse:5.5 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

592.1
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 474.4
2411 Female, age 72, unknown 597.0
2019 Male, age 18, unknown 531.9
1870 Female, age 42, unknown 510.8
1827 Male, age 72, unknown 490.1
1833 Male, age 53, unknown 465.4
2219 Male, age 76, both hemispheres 449.0
2586 Male, age 75, left hemisphere 433.9
2828 Female, age 72, unknown 429.2
1830 Male, age 51, unknown 419.3
2666 Male, age 74, left hemisphere 417.0
Dorsal raphe nucleus
nTPM: 476.0
1828 Male, age 53, unknown 530.4
2298 Female, age 72, unknown 504.7
2750 Male, age 76, both hemispheres 500.9
2047 Male, age 72, unknown 448.7
2016 Female, age 72, unknown 395.3
Inferior colliculus
nTPM: 502.4
2097 Female, age 72, unknown 607.3
1890 Male, age 53, unknown 558.8
1848 Female, age 42, unknown 460.6
2849 Male, age 72, unknown 383.0
Median raphe nucleus
nTPM: 455.8
2220 Male, age 76, midline 455.8
Periaquaductal grey, anterior
nTPM: 450.7
1947 Male, age 18, unknown 469.1
1795 Male, age 51, unknown 462.8
2502 Female, age 75, unknown 420.4
Periaquaductal grey, dorsal
nTPM: 357.7
2464 Female, age 72, unknown 376.2
1831 Male, age 72, unknown 366.3
1840 Male, age 53, unknown 352.4
2850 Male, age 76, both hemispheres 336.0
Periaquaductal grey, lateral
nTPM: 358.7
2272 Male, age 74, both hemispheres 401.4
2053 Male, age 18, unknown 367.0
2140 Male, age 76, both hemispheres 307.9
Pretectal area
nTPM: 458.2
2007 Male, age 72, unknown 643.4
1817 Female, age 42, unknown 606.3
1816 Male, age 51, unknown 522.6
1944 Female, age 72, unknown 519.8
1815 Male, age 53, unknown 471.0
2224 Female, age 72, unknown 429.6
2667 Female, age 75, unknown 422.7
2273 Male, age 74, both hemispheres 398.7
2825 Male, age 18, unknown 389.4
2316 Male, age 76, right hemisphere 384.6
2407 Male, age 75, both hemispheres 252.4
Red nucleus
nTPM: 592.1
2588 Male, age 74, left hemisphere 806.9
2725 Female, age 75, unknown 711.0
2503 Female, age 72, unknown 701.4
1821 Female, age 72, unknown 698.5
2227 Male, age 72, unknown 604.1
2769 Male, age 72, unknown 581.3
2785 Male, age 18, unknown 539.8
1865 Male, age 51, unknown 536.1
1954 Female, age 42, unknown 528.9
2823 Male, age 76, right hemisphere 514.6
1904 Male, age 53, unknown 501.9
2584 Male, age 75, left hemisphere 381.2
Substantia nigra
nTPM: 566.3
1916 Female, age 42, unknown 769.0
1851 Male, age 51, unknown 659.3
1889 Female, age 72, unknown 605.5
2665 Male, age 74, both hemispheres 592.2
1941 Male, age 53, unknown 585.5
2241 Male, age 72, unknown 543.5
2699 Male, age 18, unknown 541.6
2409 Female, age 72, unknown 523.8
2590 Female, age 75, unknown 446.1
2583 Male, age 75, right hemisphere 396.9
Superior colliculus
nTPM: 410.0
2587 Male, age 74, left hemisphere 477.6
1796 Male, age 53, unknown 467.3
2668 Female, age 75, unknown 464.9
2087 Female, age 72, unknown 463.7
2261 Male, age 18, unknown 422.5
1895 Male, age 76, right hemisphere 417.9
1839 Male, age 51, unknown 405.4
1913 Female, age 42, unknown 386.8
1995 Male, age 72, unknown 352.2
2664 Male, age 75, both hemispheres 241.5
Ventral tegmental area
nTPM: 545.3
2223 Female, age 72, unknown 637.3
2410 Female, age 72, unknown 614.1
1915 Female, age 42, unknown 590.2
2218 Male, age 76, both hemispheres 581.4
1942 Male, age 51, unknown 456.5
2021 Male, age 53, unknown 392.4

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

1331.1
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 1331.1
Samples: 139

Max nTPM: 3889.9
Min nTPM: 547.0
Std nTPM: 468.2
Median nTPM: 1296.6
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 3889.9
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 2819.9
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 2654.9
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 2526.7
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 2509.9
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 2400.0
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 2234.2
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 2184.7
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 2139.2
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 2061.1
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 2034.7
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 1887.0
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 1886.8
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 1839.9
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 1831.1
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 1797.5
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 1781.1
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 1715.3
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 1682.0
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 1663.8
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 1649.3
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 1648.3
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 1637.4
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 1617.7
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 1616.1
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 1609.9
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 1588.6
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 1578.4
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 1569.1
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 1548.0
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 1539.7
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 1536.7
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 1524.0
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 1521.9
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 1508.2
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 1501.7
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 1501.6
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 1489.9
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 1482.4
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 1477.6
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 1464.0
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 1460.8
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 1454.5
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 1454.0
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 1446.2
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 1446.1
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 1442.8
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 1425.8
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 1425.8
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 1424.4
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 1412.8
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 1409.2
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 1402.1
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 1398.9
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 1389.6
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 1365.2
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 1362.4
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 1360.6
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 1359.0
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 1355.2
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 1354.0
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 1348.5
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 1340.3
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 1336.8
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 1316.2
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 1316.1
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 1314.7
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 1309.5
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 1301.5
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 1296.6
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 1288.7
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 1268.1
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 1250.8
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 1236.4
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 1204.2
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 1197.7
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 1189.2
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 1187.5
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 1174.7
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 1170.8
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 1160.3
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 1159.6
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 1154.9
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 1147.5
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 1146.1
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 1145.3
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 1143.8
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 1138.8
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 1135.9
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 1133.4
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 1128.9
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 1121.3
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 1120.5
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 1116.8
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 1075.4
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 1063.0
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 1062.0
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 1061.1
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 1040.5
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 1037.4
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 1028.3
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 1026.8
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 1018.0
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 1017.2
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 1007.2
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 996.5
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 994.9
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 991.2
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 987.5
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 982.0
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 975.2
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 955.9
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 953.6
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 953.4
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 951.6
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 946.0
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 944.2
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 939.5
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 925.9
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 924.5
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 911.7
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 890.1
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 876.8
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 875.1
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 868.4
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 867.9
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 867.9
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 847.5
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 810.8
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 803.9
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 799.2
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 783.9
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 759.9
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 706.6
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 702.2
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 671.5
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 666.6
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 600.2
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 547.0
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

533.2
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 533.2
FF:10158-103A5 76 years, female 533.2

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

125.5
Pig sample Sample description nTPM
Substantia nigra
nTPM: 105.1
Samples: 4

Max nTPM: 148.8
Min nTPM: 77.7
Sample A Female 148.8
Sample B Female 84.2
Sample C Male 109.5
Sample D Male 77.7
Midbrain
nTPM: 111.5
Samples: 4

Max nTPM: 126.4
Min nTPM: 101.5
Sample A Female 115.2
Sample B Female 101.5
Sample C Male 126.4
Sample D Male 102.8
Periaqueductal gray
nTPM: 86.7
Samples: 3

Max nTPM: 104.7
Min nTPM: 75.9
Sample B Female 79.6
Sample C Male 104.7
Sample D Male 75.9
Superior colliculi
nTPM: 125.5
Samples: 4

Max nTPM: 148.2
Min nTPM: 102.2
Sample A Female 145.7
Sample B Female 102.2
Sample C Male 148.2
Sample D Male 105.8

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

356.9
Mouse sample Sample description nTPM
Midbrain
nTPM: 356.9
Samples: 4

Max nTPM: 415.7
Min nTPM: 310.8
Sample A Male 415.7
Sample B Male 334.8
Sample C Female 310.8
Sample D Female 366.3

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

5.5
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 5.5
69080022 Antisense, RP_050324_01_D12, Mouse strain C57BL/6J (56 days, male) 5.5

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