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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:414.0 nTPM
HPA Brain:106.7 nTPM
GTEx:414.0 nTPM
FANTOM5:222.9 Scaled Tags Per Million
Pig:361.9 nTPM
Mouse:196.6 nTPM
Allen mouse:3.0 Expression energy

MIDBRAIN - Annotated protein expression
Pending normal tissue analysis

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

106.7
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 96.5
1870 Female, age 42, unknown 119.5
2666 Male, age 74, left hemisphere 112.2
2219 Male, age 76, both hemispheres 104.8
2586 Male, age 75, left hemisphere 100.5
1827 Male, age 72, unknown 94.9
1833 Male, age 53, unknown 89.7
2411 Female, age 72, unknown 86.9
2019 Male, age 18, unknown 86.3
1830 Male, age 51, unknown 86.2
2828 Female, age 72, unknown 83.7
Dorsal raphe nucleus
nTPM: 89.8
2016 Female, age 72, unknown 95.0
2298 Female, age 72, unknown 95.0
1828 Male, age 53, unknown 89.3
2750 Male, age 76, both hemispheres 86.2
2047 Male, age 72, unknown 83.4
Inferior colliculus
nTPM: 94.9
2849 Male, age 72, unknown 104.8
1890 Male, age 53, unknown 104.2
1848 Female, age 42, unknown 91.0
2097 Female, age 72, unknown 79.5
Median raphe nucleus
nTPM: 97.9
2220 Male, age 76, midline 97.9
Periaquaductal grey, anterior
nTPM: 88.4
2502 Female, age 75, unknown 97.8
1947 Male, age 18, unknown 85.4
1795 Male, age 51, unknown 81.9
Periaquaductal grey, dorsal
nTPM: 95.6
1840 Male, age 53, unknown 106.8
2850 Male, age 76, both hemispheres 103.0
1831 Male, age 72, unknown 95.9
2464 Female, age 72, unknown 76.8
Periaquaductal grey, lateral
nTPM: 78.9
2053 Male, age 18, unknown 92.1
2140 Male, age 76, both hemispheres 81.5
2272 Male, age 74, both hemispheres 63.2
Pretectal area
nTPM: 87.9
1817 Female, age 42, unknown 97.8
1815 Male, age 53, unknown 96.1
1816 Male, age 51, unknown 93.7
2007 Male, age 72, unknown 92.5
2825 Male, age 18, unknown 92.0
2407 Male, age 75, both hemispheres 88.3
2224 Female, age 72, unknown 87.1
2667 Female, age 75, unknown 85.5
1944 Female, age 72, unknown 84.1
2316 Male, age 76, right hemisphere 82.9
2273 Male, age 74, both hemispheres 66.6
Red nucleus
nTPM: 104.8
2503 Female, age 72, unknown 132.1
1821 Female, age 72, unknown 121.6
2588 Male, age 74, left hemisphere 112.4
1865 Male, age 51, unknown 109.7
1904 Male, age 53, unknown 106.5
2584 Male, age 75, left hemisphere 105.4
2227 Male, age 72, unknown 98.0
1954 Female, age 42, unknown 96.3
2725 Female, age 75, unknown 96.2
2769 Male, age 72, unknown 94.0
2823 Male, age 76, right hemisphere 93.9
2785 Male, age 18, unknown 91.3
Substantia nigra
nTPM: 106.7
2409 Female, age 72, unknown 138.8
2699 Male, age 18, unknown 118.4
2665 Male, age 74, both hemispheres 117.9
1851 Male, age 51, unknown 114.6
2241 Male, age 72, unknown 103.0
2590 Female, age 75, unknown 102.6
1889 Female, age 72, unknown 102.0
1916 Female, age 42, unknown 100.6
1941 Male, age 53, unknown 94.6
2583 Male, age 75, right hemisphere 74.9
Superior colliculus
nTPM: 97.2
1913 Female, age 42, unknown 113.8
2587 Male, age 74, left hemisphere 112.0
1995 Male, age 72, unknown 106.4
2668 Female, age 75, unknown 99.1
1895 Male, age 76, right hemisphere 97.0
1839 Male, age 51, unknown 96.2
2664 Male, age 75, both hemispheres 92.0
2261 Male, age 18, unknown 90.6
1796 Male, age 53, unknown 87.2
2087 Female, age 72, unknown 77.3
Ventral tegmental area
nTPM: 96.2
2223 Female, age 72, unknown 114.4
1915 Female, age 42, unknown 110.7
1942 Male, age 51, unknown 93.4
2021 Male, age 53, unknown 90.4
2218 Male, age 76, both hemispheres 88.2
2410 Female, age 72, unknown 79.9

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

414.0
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 414.0
Samples: 139

Max nTPM: 1194.0
Min nTPM: 204.9
Std nTPM: 148.9
Median nTPM: 381.0
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 1194.0
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 1142.7
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 910.4
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 730.8
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 701.0
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 666.6
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 647.7
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 645.4
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 634.0
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 633.5
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 628.1
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 609.9
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 583.8
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 581.4
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 574.4
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 571.4
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 551.6
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 549.5
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 547.2
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 533.4
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 526.0
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 515.7
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 510.8
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 510.0
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 505.3
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 503.0
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 498.5
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 494.2
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 494.0
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 492.1
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 491.1
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 489.7
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 480.9
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 474.9
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 474.4
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 472.5
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 470.2
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 465.8
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 464.0
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 460.0
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 459.8
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 459.1
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 456.2
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 455.9
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 453.0
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 447.7
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 445.2
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 438.5
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 437.9
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 433.6
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 432.6
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 429.2
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 424.1
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 420.2
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 418.4
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 411.6
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 409.6
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 407.9
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 404.8
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 403.7
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 400.7
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 398.7
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 395.7
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 395.6
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 395.3
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 393.6
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 389.9
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 387.6
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 384.2
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 381.0
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 380.0
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 375.0
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 373.3
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 372.2
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 371.3
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 367.3
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 367.0
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 363.8
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 362.7
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 359.9
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 355.0
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 355.0
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 353.4
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 352.4
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 351.8
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 349.1
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 346.8
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 346.7
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 346.2
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 344.9
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 338.7
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 338.0
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 337.5
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 335.5
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 334.6
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 334.3
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 332.5
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 330.8
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 328.2
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 326.6
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 322.7
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 322.1
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 321.8
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 321.1
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 320.2
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 317.8
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 315.9
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 314.5
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 313.5
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 311.9
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 311.9
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 311.2
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 308.3
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 308.0
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 306.9
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 304.2
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 297.8
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 287.8
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 286.3
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 285.8
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 285.1
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 285.0
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 284.7
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 282.3
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 273.8
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 273.5
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 267.8
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 264.9
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 262.7
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 262.1
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 258.6
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 253.5
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 243.7
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 243.5
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 231.2
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 220.4
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 218.5
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 207.6
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 204.9
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

222.9
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 222.9
FF:10158-103A5 76 years, female 222.9

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

361.9
Pig sample Sample description nTPM
Substantia nigra
nTPM: 361.9
Samples: 4

Max nTPM: 503.8
Min nTPM: 258.0
Sample A Female 503.8
Sample B Female 368.3
Sample C Male 317.3
Sample D Male 258.0
Midbrain
nTPM: 342.0
Samples: 4

Max nTPM: 430.8
Min nTPM: 250.6
Sample A Female 430.8
Sample B Female 395.2
Sample C Male 291.4
Sample D Male 250.6
Periaqueductal gray
nTPM: 293.0
Samples: 3

Max nTPM: 308.2
Min nTPM: 272.9
Sample B Female 297.8
Sample C Male 308.2
Sample D Male 272.9
Superior colliculi
nTPM: 343.3
Samples: 4

Max nTPM: 426.5
Min nTPM: 270.4
Sample A Female 426.5
Sample B Female 270.4
Sample C Male 372.8
Sample D Male 303.4

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

196.6
Mouse sample Sample description nTPM
Midbrain
nTPM: 196.6
Samples: 4

Max nTPM: 205.1
Min nTPM: 187.5
Sample A Male 197.9
Sample B Male 205.1
Sample C Female 187.5
Sample D Female 195.9

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

3.0
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 3.0
68445143 Antisense, RP_050111_02_H03, Mouse strain C57BL/6J (56 days, male) 3.0

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