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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:293.8 nTPM
HPA Brain:180.5 nTPM
GTEx:293.8 nTPM
FANTOM5:488.1 Scaled Tags Per Million
Pig:143.8 nTPM
Mouse:101.0 nTPM
Allen mouse:7.0 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

180.5
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 157.2
2019 Male, age 18, unknown 200.0
2666 Male, age 74, left hemisphere 194.6
2586 Male, age 75, left hemisphere 181.4
1827 Male, age 72, unknown 153.3
2411 Female, age 72, unknown 153.0
2828 Female, age 72, unknown 143.1
1830 Male, age 51, unknown 142.0
1833 Male, age 53, unknown 141.4
1870 Female, age 42, unknown 138.7
2219 Male, age 76, both hemispheres 124.6
Dorsal raphe nucleus
nTPM: 139.7
2750 Male, age 76, both hemispheres 170.0
1828 Male, age 53, unknown 157.2
2047 Male, age 72, unknown 128.1
2298 Female, age 72, unknown 126.3
2016 Female, age 72, unknown 116.7
Inferior colliculus
nTPM: 129.9
1890 Male, age 53, unknown 158.7
2097 Female, age 72, unknown 140.5
1848 Female, age 42, unknown 110.3
2849 Male, age 72, unknown 110.3
Median raphe nucleus
nTPM: 164.1
2220 Male, age 76, midline 164.1
Periaquaductal grey, anterior
nTPM: 130.5
2502 Female, age 75, unknown 144.0
1795 Male, age 51, unknown 127.3
1947 Male, age 18, unknown 120.0
Periaquaductal grey, dorsal
nTPM: 132.1
2850 Male, age 76, both hemispheres 171.9
1831 Male, age 72, unknown 146.3
2464 Female, age 72, unknown 122.6
1840 Male, age 53, unknown 87.6
Periaquaductal grey, lateral
nTPM: 126.6
2140 Male, age 76, both hemispheres 148.5
2053 Male, age 18, unknown 118.5
2272 Male, age 74, both hemispheres 112.7
Pretectal area
nTPM: 156.0
2007 Male, age 72, unknown 207.3
1817 Female, age 42, unknown 197.5
1815 Male, age 53, unknown 189.5
1816 Male, age 51, unknown 180.6
1944 Female, age 72, unknown 171.5
2407 Male, age 75, both hemispheres 157.5
2667 Female, age 75, unknown 133.0
2316 Male, age 76, right hemisphere 129.0
2825 Male, age 18, unknown 120.4
2224 Female, age 72, unknown 115.2
2273 Male, age 74, both hemispheres 114.5
Red nucleus
nTPM: 180.5
1904 Male, age 53, unknown 207.9
2785 Male, age 18, unknown 204.1
1821 Female, age 72, unknown 202.0
1865 Male, age 51, unknown 197.1
1954 Female, age 42, unknown 176.1
2503 Female, age 72, unknown 175.8
2588 Male, age 74, left hemisphere 175.0
2227 Male, age 72, unknown 171.8
2769 Male, age 72, unknown 168.7
2823 Male, age 76, right hemisphere 165.2
2725 Female, age 75, unknown 164.9
2584 Male, age 75, left hemisphere 156.9
Substantia nigra
nTPM: 174.7
1916 Female, age 42, unknown 235.9
1851 Male, age 51, unknown 189.3
2699 Male, age 18, unknown 180.6
1889 Female, age 72, unknown 173.7
2583 Male, age 75, right hemisphere 168.9
1941 Male, age 53, unknown 167.1
2409 Female, age 72, unknown 166.1
2665 Male, age 74, both hemispheres 163.3
2590 Female, age 75, unknown 150.8
2241 Male, age 72, unknown 150.7
Superior colliculus
nTPM: 148.3
2668 Female, age 75, unknown 191.0
1913 Female, age 42, unknown 164.6
1995 Male, age 72, unknown 154.8
2087 Female, age 72, unknown 153.6
2587 Male, age 74, left hemisphere 144.0
2261 Male, age 18, unknown 140.7
2664 Male, age 75, both hemispheres 140.3
1796 Male, age 53, unknown 138.0
1839 Male, age 51, unknown 129.8
1895 Male, age 76, right hemisphere 126.8
Ventral tegmental area
nTPM: 152.7
2223 Female, age 72, unknown 173.3
2410 Female, age 72, unknown 168.9
1915 Female, age 42, unknown 160.6
2218 Male, age 76, both hemispheres 144.1
1942 Male, age 51, unknown 135.7
2021 Male, age 53, unknown 133.6

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

293.8
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 293.8
Samples: 139

Max nTPM: 598.9
Min nTPM: 155.3
Std nTPM: 87.2
Median nTPM: 265.2
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 598.9
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 579.0
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 551.5
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 522.2
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 521.9
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 502.6
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 499.4
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 475.6
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 475.2
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 466.7
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 460.9
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 460.8
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 439.4
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 403.3
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 391.5
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 391.0
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 390.1
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 386.2
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 381.5
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 378.7
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 378.3
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 369.2
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 361.3
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 358.7
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 358.3
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 353.6
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 353.3
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 348.5
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 344.6
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 341.0
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 339.2
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 336.6
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 336.0
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 335.9
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 333.0
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 330.3
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 328.9
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 328.1
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 326.6
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 323.7
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 323.5
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 320.8
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 316.4
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 315.9
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 314.9
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 314.1
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 314.0
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 313.9
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 310.7
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 309.2
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 309.0
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 307.6
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 304.1
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 302.3
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 299.7
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 295.3
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 294.1
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 290.7
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 284.4
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 282.8
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 278.1
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 277.6
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 276.4
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 276.1
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 273.0
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 271.8
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 270.7
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 269.4
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 267.1
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 265.2
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 261.3
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 260.8
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 260.5
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 258.6
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 258.1
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 257.3
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 254.8
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 254.3
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 252.8
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 252.6
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 252.4
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 252.1
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 251.7
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 250.5
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 249.7
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 246.9
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 246.5
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 245.8
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 245.5
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 244.9
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 244.8
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 244.6
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 243.9
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 243.1
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 242.1
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 242.0
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 240.3
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 239.9
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 239.9
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 239.8
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 239.5
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 239.3
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 237.6
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 236.8
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 235.9
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 234.2
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 234.0
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 232.7
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 231.7
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 230.0
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 229.6
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 228.8
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 228.8
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 227.9
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 227.0
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 224.7
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 222.9
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 222.9
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 218.3
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 215.7
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 213.3
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 213.0
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 212.9
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 210.4
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 208.7
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 208.3
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 207.0
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 206.5
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 204.4
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 200.4
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 199.2
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 197.3
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 195.1
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 193.6
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 190.4
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 186.1
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 176.5
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 168.3
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 155.3
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

488.1
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 488.1
FF:10158-103A5 76 years, female 488.1

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

143.8
Pig sample Sample description nTPM
Substantia nigra
nTPM: 132.6
Samples: 4

Max nTPM: 143.8
Min nTPM: 117.6
Sample A Female 143.8
Sample B Female 117.6
Sample C Male 131.9
Sample D Male 137.1
Midbrain
nTPM: 143.8
Samples: 4

Max nTPM: 202.0
Min nTPM: 114.1
Sample A Female 202.0
Sample B Female 114.1
Sample C Male 132.4
Sample D Male 126.6
Periaqueductal gray
nTPM: 104.0
Samples: 3

Max nTPM: 113.6
Min nTPM: 98.5
Sample B Female 99.9
Sample C Male 113.6
Sample D Male 98.5
Superior colliculi
nTPM: 143.0
Samples: 4

Max nTPM: 169.3
Min nTPM: 113.0
Sample A Female 169.3
Sample B Female 113.0
Sample C Male 146.3
Sample D Male 143.4

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

101.0
Mouse sample Sample description nTPM
Midbrain
nTPM: 101.0
Samples: 4

Max nTPM: 106.9
Min nTPM: 95.1
Sample A Male 106.9
Sample B Male 101.8
Sample C Female 95.1
Sample D Female 100.2

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

7.0
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 7.0
69288650 Antisense, RP_050407_01_D10, Mouse strain C57BL/6J (56 days, male) 7.0

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