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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:116.7 nTPM
HPA Brain:609.7 nTPM
GTEx:116.7 nTPM
FANTOM5:706.7 Scaled Tags Per Million
Pig:272.4 nTPM
Mouse:250.6 nTPM
Allen mouse:12.4 Expression energy

MIDBRAIN - Annotated protein expression
Pending normal tissue analysis

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

609.7
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 537.7
2586 Male, age 75, left hemisphere 724.9
2666 Male, age 74, left hemisphere 643.8
2828 Female, age 72, unknown 557.7
2019 Male, age 18, unknown 550.3
1827 Male, age 72, unknown 529.5
2219 Male, age 76, both hemispheres 514.5
2411 Female, age 72, unknown 502.0
1833 Male, age 53, unknown 455.1
1870 Female, age 42, unknown 452.6
1830 Male, age 51, unknown 446.3
Dorsal raphe nucleus
nTPM: 497.6
2047 Male, age 72, unknown 569.7
2750 Male, age 76, both hemispheres 563.1
1828 Male, age 53, unknown 491.0
2298 Female, age 72, unknown 488.9
2016 Female, age 72, unknown 375.4
Inferior colliculus
nTPM: 451.6
1848 Female, age 42, unknown 464.2
2849 Male, age 72, unknown 451.6
1890 Male, age 53, unknown 448.8
2097 Female, age 72, unknown 442.0
Median raphe nucleus
nTPM: 575.1
2220 Male, age 76, midline 575.1
Periaquaductal grey, anterior
nTPM: 560.3
1795 Male, age 51, unknown 571.0
1947 Male, age 18, unknown 556.8
2502 Female, age 75, unknown 553.0
Periaquaductal grey, dorsal
nTPM: 411.1
2464 Female, age 72, unknown 440.9
1840 Male, age 53, unknown 419.4
1831 Male, age 72, unknown 417.9
2850 Male, age 76, both hemispheres 366.0
Periaquaductal grey, lateral
nTPM: 382.1
2053 Male, age 18, unknown 426.8
2272 Male, age 74, both hemispheres 361.9
2140 Male, age 76, both hemispheres 357.7
Pretectal area
nTPM: 537.8
1816 Male, age 51, unknown 723.5
1944 Female, age 72, unknown 672.4
2007 Male, age 72, unknown 664.6
1817 Female, age 42, unknown 655.9
1815 Male, age 53, unknown 609.2
2407 Male, age 75, both hemispheres 486.3
2224 Female, age 72, unknown 467.9
2667 Female, age 75, unknown 459.4
2825 Male, age 18, unknown 430.6
2316 Male, age 76, right hemisphere 385.7
2273 Male, age 74, both hemispheres 360.8
Red nucleus
nTPM: 527.2
2588 Male, age 74, left hemisphere 601.9
2785 Male, age 18, unknown 584.3
2725 Female, age 75, unknown 569.5
2584 Male, age 75, left hemisphere 566.6
1865 Male, age 51, unknown 540.2
1904 Male, age 53, unknown 513.6
1821 Female, age 72, unknown 510.7
2503 Female, age 72, unknown 506.9
2769 Male, age 72, unknown 494.8
2227 Male, age 72, unknown 486.0
2823 Male, age 76, right hemisphere 480.5
1954 Female, age 42, unknown 471.5
Substantia nigra
nTPM: 609.7
1916 Female, age 42, unknown 740.3
1941 Male, age 53, unknown 690.8
2665 Male, age 74, both hemispheres 669.9
1889 Female, age 72, unknown 639.1
1851 Male, age 51, unknown 629.5
2583 Male, age 75, right hemisphere 610.8
2241 Male, age 72, unknown 586.5
2409 Female, age 72, unknown 532.3
2699 Male, age 18, unknown 518.7
2590 Female, age 75, unknown 479.4
Superior colliculus
nTPM: 529.6
2668 Female, age 75, unknown 703.2
2087 Female, age 72, unknown 608.8
2261 Male, age 18, unknown 578.8
1796 Male, age 53, unknown 565.3
2664 Male, age 75, both hemispheres 537.0
2587 Male, age 74, left hemisphere 512.6
1895 Male, age 76, right hemisphere 466.1
1913 Female, age 42, unknown 457.4
1839 Male, age 51, unknown 451.3
1995 Male, age 72, unknown 415.6
Ventral tegmental area
nTPM: 561.7
2410 Female, age 72, unknown 657.2
2218 Male, age 76, both hemispheres 600.5
2223 Female, age 72, unknown 586.3
1915 Female, age 42, unknown 557.1
1942 Male, age 51, unknown 511.3
2021 Male, age 53, unknown 458.2

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

116.7
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 116.7
Samples: 139

Max nTPM: 262.9
Min nTPM: 40.0
Std nTPM: 41.6
Median nTPM: 111.7
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 262.9
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 249.3
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 232.5
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 220.6
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 220.4
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 194.2
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 188.4
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 188.1
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 186.5
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 183.2
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 177.2
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 176.0
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 175.0
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 173.6
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 165.4
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 164.1
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 159.3
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 158.0
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 156.3
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 155.1
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 154.9
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 154.3
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 153.8
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 153.5
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 153.2
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 152.6
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 152.3
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 150.7
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 149.6
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 147.5
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 145.8
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 144.9
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 143.8
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 143.1
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 141.3
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 140.5
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 139.5
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 138.5
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 137.5
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 137.1
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 135.5
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 134.7
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 133.8
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 133.5
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 133.3
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 130.3
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 129.7
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 128.2
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 127.1
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 126.9
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 125.8
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 124.7
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 124.0
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 123.7
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 123.0
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 121.9
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 120.4
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 120.1
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 117.8
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 117.3
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 117.3
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 116.0
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 115.4
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 115.4
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 115.1
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 114.8
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 113.0
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 112.9
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 111.7
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 111.7
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 109.1
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 108.7
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 108.7
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 108.6
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 107.8
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 107.2
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 105.1
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 104.8
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 104.5
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 104.3
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 103.3
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 102.9
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 102.2
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 101.7
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 101.2
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 101.1
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 101.1
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 100.7
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 100.4
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 99.4
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 98.9
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 98.5
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 98.4
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 98.0
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 97.8
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 96.8
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 96.7
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 96.1
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 95.8
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 95.1
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 94.0
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 93.5
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 92.1
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 90.1
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 89.2
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 87.4
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 85.9
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 83.0
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 80.0
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 78.0
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 77.9
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 76.8
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 75.9
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 75.4
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 75.1
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 74.1
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 73.5
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 72.3
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 71.0
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 70.9
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 70.3
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 69.6
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 67.8
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 67.6
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 67.4
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 65.1
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 64.7
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 64.1
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 63.3
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 62.9
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 61.9
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 60.5
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 59.9
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 58.4
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 57.1
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 53.7
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 51.5
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 43.5
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 40.0
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

706.7
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 706.7
FF:10158-103A5 76 years, female 706.7

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

272.4
Pig sample Sample description nTPM
Substantia nigra
nTPM: 257.7
Samples: 4

Max nTPM: 319.1
Min nTPM: 171.5
Sample A Female 303.4
Sample B Female 171.5
Sample C Male 319.1
Sample D Male 236.6
Midbrain
nTPM: 272.4
Samples: 4

Max nTPM: 391.9
Min nTPM: 195.8
Sample A Female 257.0
Sample B Female 195.8
Sample C Male 391.9
Sample D Male 244.9
Periaqueductal gray
nTPM: 175.0
Samples: 3

Max nTPM: 201.5
Min nTPM: 153.9
Sample B Female 169.7
Sample C Male 201.5
Sample D Male 153.9
Superior colliculi
nTPM: 245.2
Samples: 4

Max nTPM: 332.4
Min nTPM: 127.6
Sample A Female 236.8
Sample B Female 127.6
Sample C Male 332.4
Sample D Male 284.0

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

250.6
Mouse sample Sample description nTPM
Midbrain
nTPM: 250.6
Samples: 4

Max nTPM: 262.0
Min nTPM: 227.4
Sample A Male 227.4
Sample B Male 258.2
Sample C Female 254.9
Sample D Female 262.0

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

12.4
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 12.4
69735759 Antisense, RP_050503_03_E02, Mouse strain C57BL/6J (56 days, male) 17.4
74513872 Antisense, RP_060208_01_E12, Mouse strain C57BL/6J (56 days, male) 7.4

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