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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:1024.4 nTPM
HPA Brain:399.8 nTPM
GTEx:1024.4 nTPM
FANTOM5:289.3 Scaled Tags Per Million
Pig:882.5 nTPM
Mouse:1311.5 nTPM
Allen mouse:12.4 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

399.8
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 315.7
2411 Female, age 72, unknown 351.4
2666 Male, age 74, left hemisphere 342.7
1827 Male, age 72, unknown 339.4
2019 Male, age 18, unknown 334.3
1870 Female, age 42, unknown 325.3
2219 Male, age 76, both hemispheres 319.0
2828 Female, age 72, unknown 312.4
1833 Male, age 53, unknown 292.0
2586 Male, age 75, left hemisphere 270.8
1830 Male, age 51, unknown 269.9
Dorsal raphe nucleus
nTPM: 304.7
1828 Male, age 53, unknown 344.5
2298 Female, age 72, unknown 325.4
2750 Male, age 76, both hemispheres 297.9
2047 Male, age 72, unknown 297.2
2016 Female, age 72, unknown 258.5
Inferior colliculus
nTPM: 330.3
1890 Male, age 53, unknown 362.2
1848 Female, age 42, unknown 333.0
2097 Female, age 72, unknown 325.5
2849 Male, age 72, unknown 300.4
Median raphe nucleus
nTPM: 314.3
2220 Male, age 76, midline 314.3
Periaquaductal grey, anterior
nTPM: 314.0
1947 Male, age 18, unknown 334.3
2502 Female, age 75, unknown 306.2
1795 Male, age 51, unknown 301.6
Periaquaductal grey, dorsal
nTPM: 258.6
1840 Male, age 53, unknown 281.6
1831 Male, age 72, unknown 262.7
2464 Female, age 72, unknown 247.1
2850 Male, age 76, both hemispheres 243.0
Periaquaductal grey, lateral
nTPM: 253.0
2272 Male, age 74, both hemispheres 260.5
2053 Male, age 18, unknown 255.5
2140 Male, age 76, both hemispheres 243.1
Pretectal area
nTPM: 338.5
1817 Female, age 42, unknown 437.4
1944 Female, age 72, unknown 420.3
2007 Male, age 72, unknown 419.6
1816 Male, age 51, unknown 405.2
2667 Female, age 75, unknown 346.9
1815 Male, age 53, unknown 344.6
2825 Male, age 18, unknown 286.4
2224 Female, age 72, unknown 275.2
2273 Male, age 74, both hemispheres 269.6
2316 Male, age 76, right hemisphere 262.8
2407 Male, age 75, both hemispheres 255.9
Red nucleus
nTPM: 365.2
2503 Female, age 72, unknown 424.2
1821 Female, age 72, unknown 406.2
2785 Male, age 18, unknown 392.9
2588 Male, age 74, left hemisphere 387.8
2725 Female, age 75, unknown 374.3
1865 Male, age 51, unknown 368.6
2227 Male, age 72, unknown 365.8
2769 Male, age 72, unknown 358.8
1954 Female, age 42, unknown 354.8
1904 Male, age 53, unknown 336.1
2823 Male, age 76, right hemisphere 318.4
2584 Male, age 75, left hemisphere 294.1
Substantia nigra
nTPM: 399.8
1916 Female, age 42, unknown 526.0
2665 Male, age 74, both hemispheres 440.9
1889 Female, age 72, unknown 434.3
1851 Male, age 51, unknown 429.0
1941 Male, age 53, unknown 410.1
2241 Male, age 72, unknown 404.8
2409 Female, age 72, unknown 399.7
2699 Male, age 18, unknown 373.1
2590 Female, age 75, unknown 291.1
2583 Male, age 75, right hemisphere 289.5
Superior colliculus
nTPM: 311.4
2668 Female, age 75, unknown 394.7
2087 Female, age 72, unknown 383.1
1895 Male, age 76, right hemisphere 352.6
1796 Male, age 53, unknown 331.0
2587 Male, age 74, left hemisphere 330.3
2261 Male, age 18, unknown 303.1
1839 Male, age 51, unknown 280.5
1913 Female, age 42, unknown 271.2
1995 Male, age 72, unknown 242.0
2664 Male, age 75, both hemispheres 225.8
Ventral tegmental area
nTPM: 338.8
1915 Female, age 42, unknown 397.2
2410 Female, age 72, unknown 376.6
2218 Male, age 76, both hemispheres 359.3
1942 Male, age 51, unknown 328.7
2223 Female, age 72, unknown 325.7
2021 Male, age 53, unknown 245.3

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

1024.4
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 1024.4
Samples: 139

Max nTPM: 2619.5
Min nTPM: 552.7
Std nTPM: 310.8
Median nTPM: 965.2
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 2619.5
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 2337.3
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 1907.7
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 1824.2
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 1694.1
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 1592.8
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 1588.8
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 1586.2
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 1560.3
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 1547.0
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 1525.7
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 1405.2
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 1400.0
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 1386.6
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 1372.8
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 1320.0
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 1309.9
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 1306.2
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 1263.1
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 1236.4
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 1234.8
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 1228.4
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 1218.6
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 1216.9
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 1215.1
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 1208.2
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 1205.8
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 1200.3
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 1178.5
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 1168.4
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 1160.1
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 1158.6
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 1155.2
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 1145.4
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 1142.5
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 1140.2
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 1139.4
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 1133.7
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 1132.9
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 1126.1
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 1116.4
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 1106.3
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 1103.5
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 1100.4
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 1093.7
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 1092.9
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 1090.9
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 1088.3
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 1087.1
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 1085.6
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 1081.8
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 1080.5
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 1075.1
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 1064.1
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 1048.8
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 1047.1
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 1042.8
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 1038.8
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 1038.6
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 1037.4
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 1021.6
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 1019.9
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 1018.5
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 1010.8
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 1009.0
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 993.9
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 989.7
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 977.7
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 970.0
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 965.2
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 965.2
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 962.1
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 961.3
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 953.4
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 952.3
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 945.3
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 941.4
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 933.5
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 933.5
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 932.7
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 913.6
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 912.1
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 908.6
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 905.8
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 899.5
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 899.0
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 894.6
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 893.0
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 884.4
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 882.5
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 880.1
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 878.8
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 868.1
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 866.9
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 866.8
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 862.4
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 862.4
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 857.3
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 848.0
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 842.5
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 839.4
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 837.7
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 835.3
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 833.2
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 831.6
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 828.7
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 823.5
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 810.4
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 801.9
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 793.7
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 789.8
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 784.0
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 781.8
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 780.3
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 767.3
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 766.2
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 755.8
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 755.4
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 753.5
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 735.4
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 734.0
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 727.3
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 723.7
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 713.7
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 712.6
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 705.1
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 699.8
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 671.2
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 665.7
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 664.3
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 663.7
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 653.5
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 638.9
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 624.0
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 623.3
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 622.1
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 604.4
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 594.5
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 552.7
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

289.3
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 289.3
FF:10158-103A5 76 years, female 289.3

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

882.5
Pig sample Sample description nTPM
Substantia nigra
nTPM: 674.7
Samples: 4

Max nTPM: 894.1
Min nTPM: 523.3
Sample A Female 894.1
Sample B Female 523.3
Sample C Male 692.1
Sample D Male 589.3
Midbrain
nTPM: 786.3
Samples: 4

Max nTPM: 1031.8
Min nTPM: 642.3
Sample A Female 778.9
Sample B Female 692.1
Sample C Male 1031.8
Sample D Male 642.3
Periaqueductal gray
nTPM: 536.8
Samples: 3

Max nTPM: 597.0
Min nTPM: 450.7
Sample B Female 562.7
Sample C Male 597.0
Sample D Male 450.7
Superior colliculi
nTPM: 882.6
Samples: 4

Max nTPM: 1098.4
Min nTPM: 688.9
Sample A Female 971.3
Sample B Female 688.9
Sample C Male 1098.4
Sample D Male 771.6

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

1311.5
Mouse sample Sample description nTPM
Midbrain
nTPM: 1311.5
Samples: 4

Max nTPM: 1487.4
Min nTPM: 1158.6
Sample A Male 1487.4
Sample B Male 1227.3
Sample C Female 1158.6
Sample D Female 1372.6

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

12.4
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 12.4
69568980 Antisense, RP_050426_03_C01, Mouse strain C57BL/6J (56 days, male) 12.8
73992933 Antisense, RP_051214_03_C11, Mouse strain C57BL/6J (56 days, male) 12.0

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