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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:42.0 nTPM
HPA Brain:169.4 nTPM
GTEx:42.0 nTPM
FANTOM5:48.5 Scaled Tags Per Million
Pig:113.6 nTPM
Mouse:186.9 nTPM
Allen mouse:10.4 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

169.4
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 132.8
2219 Male, age 76, both hemispheres 180.0
2666 Male, age 74, left hemisphere 163.9
1827 Male, age 72, unknown 162.3
2828 Female, age 72, unknown 136.5
2586 Male, age 75, left hemisphere 130.0
2019 Male, age 18, unknown 128.0
1870 Female, age 42, unknown 116.2
1833 Male, age 53, unknown 115.2
1830 Male, age 51, unknown 101.0
2411 Female, age 72, unknown 95.1
Dorsal raphe nucleus
nTPM: 109.8
2298 Female, age 72, unknown 126.0
1828 Male, age 53, unknown 114.9
2047 Male, age 72, unknown 110.7
2750 Male, age 76, both hemispheres 108.3
2016 Female, age 72, unknown 89.2
Inferior colliculus
nTPM: 141.6
2849 Male, age 72, unknown 184.9
1848 Female, age 42, unknown 137.9
2097 Female, age 72, unknown 126.9
1890 Male, age 53, unknown 116.7
Median raphe nucleus
nTPM: 169.4
2220 Male, age 76, midline 169.4
Periaquaductal grey, anterior
nTPM: 157.8
1795 Male, age 51, unknown 173.3
2502 Female, age 75, unknown 153.1
1947 Male, age 18, unknown 147.0
Periaquaductal grey, dorsal
nTPM: 137.2
1831 Male, age 72, unknown 140.8
1840 Male, age 53, unknown 140.2
2850 Male, age 76, both hemispheres 139.4
2464 Female, age 72, unknown 128.4
Periaquaductal grey, lateral
nTPM: 121.4
2140 Male, age 76, both hemispheres 127.0
2272 Male, age 74, both hemispheres 121.7
2053 Male, age 18, unknown 115.6
Pretectal area
nTPM: 160.5
1816 Male, age 51, unknown 226.4
1817 Female, age 42, unknown 210.0
1944 Female, age 72, unknown 185.1
2007 Male, age 72, unknown 180.4
2667 Female, age 75, unknown 172.3
1815 Male, age 53, unknown 163.8
2825 Male, age 18, unknown 141.9
2224 Female, age 72, unknown 137.8
2316 Male, age 76, right hemisphere 118.5
2407 Male, age 75, both hemispheres 118.5
2273 Male, age 74, both hemispheres 111.2
Red nucleus
nTPM: 90.3
2785 Male, age 18, unknown 121.2
2584 Male, age 75, left hemisphere 113.0
2725 Female, age 75, unknown 108.7
2588 Male, age 74, left hemisphere 107.7
1821 Female, age 72, unknown 86.9
2823 Male, age 76, right hemisphere 84.8
2227 Male, age 72, unknown 84.6
2769 Male, age 72, unknown 83.8
1954 Female, age 42, unknown 83.6
2503 Female, age 72, unknown 72.3
1904 Male, age 53, unknown 69.8
1865 Male, age 51, unknown 67.5
Substantia nigra
nTPM: 107.8
2665 Male, age 74, both hemispheres 148.3
1889 Female, age 72, unknown 147.1
1941 Male, age 53, unknown 145.5
1916 Female, age 42, unknown 115.4
1851 Male, age 51, unknown 96.0
2583 Male, age 75, right hemisphere 94.3
2590 Female, age 75, unknown 87.5
2241 Male, age 72, unknown 84.1
2409 Female, age 72, unknown 81.4
2699 Male, age 18, unknown 79.0
Superior colliculus
nTPM: 131.4
2087 Female, age 72, unknown 164.9
2261 Male, age 18, unknown 157.6
1895 Male, age 76, right hemisphere 148.8
2664 Male, age 75, both hemispheres 144.7
1796 Male, age 53, unknown 144.3
1839 Male, age 51, unknown 142.6
2668 Female, age 75, unknown 117.4
1913 Female, age 42, unknown 108.1
2587 Male, age 74, left hemisphere 96.2
1995 Male, age 72, unknown 89.3
Ventral tegmental area
nTPM: 115.6
2218 Male, age 76, both hemispheres 141.9
2223 Female, age 72, unknown 124.0
1942 Male, age 51, unknown 119.5
2021 Male, age 53, unknown 111.8
1915 Female, age 42, unknown 107.5
2410 Female, age 72, unknown 88.8

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

42.0
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 42.0
Samples: 139

Max nTPM: 147.7
Min nTPM: 9.7
Std nTPM: 24.2
Median nTPM: 36.9
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 147.7
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 109.9
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 102.7
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 101.5
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 95.7
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 94.3
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 92.8
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 90.6
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 88.5
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 87.1
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 85.3
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 83.1
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 78.9
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 76.4
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 76.4
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 72.6
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 71.7
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 67.2
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 67.1
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 66.3
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 66.1
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 62.3
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 61.5
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 59.9
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 59.6
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 58.6
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 58.5
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 56.3
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 55.6
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 55.6
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 55.6
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 55.6
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 55.3
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 55.1
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 54.2
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 54.2
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 54.1
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 52.9
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 52.6
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 52.3
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 52.0
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 51.9
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 51.8
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 51.4
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 51.0
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 50.8
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 50.5
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 48.2
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 47.9
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 46.9
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 46.6
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 46.3
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 46.3
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 45.7
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 45.7
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 45.0
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 44.7
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 44.6
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 43.8
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 43.0
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 42.2
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 41.9
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 41.9
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 41.3
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 41.2
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 40.4
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 38.6
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 38.1
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 37.9
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 36.9
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 36.1
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 34.6
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 33.9
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 32.7
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 32.6
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 32.5
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 32.2
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 31.7
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 31.6
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 30.6
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 30.4
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 29.6
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 29.1
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 29.0
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 28.6
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 28.5
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 28.4
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 27.4
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 27.1
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 26.7
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 25.9
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 25.7
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 25.6
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 25.3
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 25.2
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 24.6
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 24.6
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 24.6
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 24.5
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 24.0
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 23.8
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 23.8
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 23.6
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 23.0
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 23.0
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 22.9
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 22.9
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 22.1
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 21.8
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 21.7
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 21.6
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 21.5
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 21.4
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 21.3
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 21.2
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 20.9
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 20.4
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 20.1
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 20.1
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 20.0
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 19.5
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 18.3
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 18.3
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 17.8
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 17.8
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 17.4
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 17.4
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 16.4
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 16.2
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 16.0
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 15.2
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 15.0
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 14.9
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 14.3
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 13.3
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 12.9
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 11.9
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 11.4
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 9.7
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

48.5
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 48.5
FF:10158-103A5 76 years, female 48.5

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

113.6
Pig sample Sample description nTPM
Substantia nigra
nTPM: 74.4
Samples: 4

Max nTPM: 110.0
Min nTPM: 36.1
Sample A Female 94.1
Sample B Female 57.2
Sample C Male 110.0
Sample D Male 36.1
Midbrain
nTPM: 108.4
Samples: 4

Max nTPM: 170.4
Min nTPM: 34.3
Sample A Female 34.3
Sample B Female 78.3
Sample C Male 170.4
Sample D Male 150.6
Periaqueductal gray
nTPM: 82.7
Samples: 3

Max nTPM: 102.9
Min nTPM: 69.1
Sample B Female 76.0
Sample C Male 102.9
Sample D Male 69.1
Superior colliculi
nTPM: 113.6
Samples: 4

Max nTPM: 128.3
Min nTPM: 88.0
Sample A Female 115.2
Sample B Female 88.0
Sample C Male 128.3
Sample D Male 122.8

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

186.9
Mouse sample Sample description nTPM
Midbrain
nTPM: 186.9
Samples: 4

Max nTPM: 204.6
Min nTPM: 169.3
Sample A Male 204.6
Sample B Male 169.3
Sample C Female 188.0
Sample D Female 185.7

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

10.4
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 10.4
68193007 Antisense, RP_040922_01_D12, Mouse strain C57BL/6J (56 days, male) 16.2
72109445 Antisense, RP_050712_04_G07, Mouse strain C57BL/6J (56 days, male) 9.5
72182975 Antisense, RP_050719_03_A03, Mouse strain C57BL/6J (56 days, male) 5.5
70918916 Antisense, RP_050712_04_G07, Mouse strain C57BL/6J (56 days, male) 5.3

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