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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:234.0 nTPM
HPA Brain:261.4 nTPM
GTEx:234.0 nTPM
FANTOM5:375.5 Scaled Tags Per Million
Pig:546.4 nTPM
Mouse:448.3 nTPM
Allen mouse:1.4 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

261.4
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 240.4
2411 Female, age 72, unknown 293.5
1870 Female, age 42, unknown 272.2
2019 Male, age 18, unknown 245.4
1833 Male, age 53, unknown 244.1
2666 Male, age 74, left hemisphere 229.7
1827 Male, age 72, unknown 227.7
1830 Male, age 51, unknown 225.8
2828 Female, age 72, unknown 225.4
2586 Male, age 75, left hemisphere 222.6
2219 Male, age 76, both hemispheres 217.5
Dorsal raphe nucleus
nTPM: 235.6
2750 Male, age 76, both hemispheres 275.3
2298 Female, age 72, unknown 256.1
2047 Male, age 72, unknown 226.8
2016 Female, age 72, unknown 210.8
1828 Male, age 53, unknown 209.2
Inferior colliculus
nTPM: 211.4
2097 Female, age 72, unknown 253.2
1890 Male, age 53, unknown 210.1
1848 Female, age 42, unknown 201.1
2849 Male, age 72, unknown 181.3
Median raphe nucleus
nTPM: 243.0
2220 Male, age 76, midline 243.0
Periaquaductal grey, anterior
nTPM: 246.4
1947 Male, age 18, unknown 263.7
2502 Female, age 75, unknown 238.8
1795 Male, age 51, unknown 236.8
Periaquaductal grey, dorsal
nTPM: 195.3
2464 Female, age 72, unknown 205.2
1831 Male, age 72, unknown 202.0
2850 Male, age 76, both hemispheres 192.7
1840 Male, age 53, unknown 181.2
Periaquaductal grey, lateral
nTPM: 194.9
2053 Male, age 18, unknown 215.9
2272 Male, age 74, both hemispheres 205.7
2140 Male, age 76, both hemispheres 163.1
Pretectal area
nTPM: 234.6
1815 Male, age 53, unknown 284.3
2007 Male, age 72, unknown 274.3
1817 Female, age 42, unknown 262.7
1816 Male, age 51, unknown 255.5
1944 Female, age 72, unknown 237.2
2224 Female, age 72, unknown 229.0
2667 Female, age 75, unknown 219.5
2825 Male, age 18, unknown 212.2
2273 Male, age 74, both hemispheres 211.1
2316 Male, age 76, right hemisphere 199.0
2407 Male, age 75, both hemispheres 195.7
Red nucleus
nTPM: 261.4
1821 Female, age 72, unknown 309.6
1904 Male, age 53, unknown 301.4
2503 Female, age 72, unknown 290.7
1954 Female, age 42, unknown 281.2
1865 Male, age 51, unknown 270.2
2785 Male, age 18, unknown 262.4
2725 Female, age 75, unknown 254.2
2823 Male, age 76, right hemisphere 247.2
2588 Male, age 74, left hemisphere 242.9
2769 Male, age 72, unknown 239.9
2227 Male, age 72, unknown 236.5
2584 Male, age 75, left hemisphere 200.4
Substantia nigra
nTPM: 239.5
2241 Male, age 72, unknown 281.7
2409 Female, age 72, unknown 261.3
1889 Female, age 72, unknown 258.3
1851 Male, age 51, unknown 257.3
1916 Female, age 42, unknown 242.9
2590 Female, age 75, unknown 239.7
1941 Male, age 53, unknown 238.1
2583 Male, age 75, right hemisphere 231.3
2699 Male, age 18, unknown 201.4
2665 Male, age 74, both hemispheres 183.4
Superior colliculus
nTPM: 230.5
1913 Female, age 42, unknown 261.6
2668 Female, age 75, unknown 254.4
2587 Male, age 74, left hemisphere 252.3
2261 Male, age 18, unknown 240.2
1995 Male, age 72, unknown 237.2
1895 Male, age 76, right hemisphere 221.3
1796 Male, age 53, unknown 216.5
1839 Male, age 51, unknown 216.3
2087 Female, age 72, unknown 214.0
2664 Male, age 75, both hemispheres 191.5
Ventral tegmental area
nTPM: 237.4
2410 Female, age 72, unknown 278.7
1915 Female, age 42, unknown 242.1
2218 Male, age 76, both hemispheres 238.0
2223 Female, age 72, unknown 233.3
1942 Male, age 51, unknown 223.7
2021 Male, age 53, unknown 208.6

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

234.0
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 234.0
Samples: 139

Max nTPM: 390.3
Min nTPM: 131.4
Std nTPM: 50.7
Median nTPM: 229.3
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 390.3
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 388.1
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 386.8
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 380.8
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 354.3
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 334.0
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 330.6
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 318.1
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 315.7
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 308.6
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 305.2
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 298.7
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 298.7
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 298.2
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 297.0
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 296.1
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 295.0
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 290.4
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 289.2
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 288.3
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 287.4
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 286.4
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 285.1
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 278.8
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 273.7
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 272.2
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 272.0
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 270.0
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 269.8
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 269.5
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 269.3
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 267.6
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 265.7
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 265.0
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 264.7
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 264.3
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 262.1
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 258.0
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 257.9
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 257.6
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 257.2
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 256.7
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 256.2
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 254.6
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 253.2
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 252.3
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 249.4
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 248.3
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 248.3
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 247.6
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 247.4
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 246.8
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 245.9
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 243.1
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 240.5
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 240.3
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 239.8
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 239.5
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 239.5
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 238.4
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 237.0
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 236.9
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 235.3
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 233.6
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 233.0
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 232.9
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 232.3
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 231.5
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 230.7
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 229.3
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 228.5
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 225.9
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 222.8
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 222.0
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 221.5
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 220.4
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 220.3
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 220.3
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 219.1
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 217.9
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 217.4
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 216.3
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 216.1
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 215.5
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 214.1
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 212.8
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 212.3
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 212.0
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 211.6
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 210.6
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 209.6
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 208.2
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 207.9
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 207.5
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 207.1
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 206.6
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 206.2
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 206.0
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 203.2
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 202.9
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 200.2
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 200.2
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 197.6
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 194.0
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 193.7
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 192.8
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 192.6
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 191.5
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 191.2
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 190.9
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 188.3
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 187.7
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 186.9
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 185.9
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 185.7
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 185.3
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 184.0
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 183.4
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 183.0
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 182.7
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 180.8
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 180.4
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 176.9
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 176.4
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 176.1
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 175.7
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 173.4
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 172.2
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 171.5
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 169.6
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 168.5
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 168.1
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 164.1
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 162.6
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 156.8
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 155.3
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 152.5
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 149.7
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 131.4
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

375.5
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 375.5
FF:10158-103A5 76 years, female 375.5

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

546.4
Pig sample Sample description nTPM
Substantia nigra
nTPM: 520.2
Samples: 4

Max nTPM: 663.8
Min nTPM: 381.8
Sample A Female 663.8
Sample B Female 381.8
Sample C Male 543.7
Sample D Male 491.6
Midbrain
nTPM: 546.4
Samples: 4

Max nTPM: 793.1
Min nTPM: 438.9
Sample A Female 793.1
Sample B Female 513.1
Sample C Male 440.6
Sample D Male 438.9
Periaqueductal gray
nTPM: 401.5
Samples: 3

Max nTPM: 422.4
Min nTPM: 368.0
Sample B Female 422.4
Sample C Male 414.2
Sample D Male 368.0
Superior colliculi
nTPM: 491.8
Samples: 4

Max nTPM: 580.7
Min nTPM: 361.7
Sample A Female 580.7
Sample B Female 361.7
Sample C Male 546.8
Sample D Male 477.8

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

448.3
Mouse sample Sample description nTPM
Midbrain
nTPM: 448.3
Samples: 4

Max nTPM: 456.9
Min nTPM: 439.9
Sample A Male 452.3
Sample B Male 439.9
Sample C Female 444.2
Sample D Female 456.9

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

1.4
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 1.4
1131 Antisense, RP_Baylor_103129, Mouse strain C57BL/6J (56 days, male) 5.5
1130 Antisense, RP_Baylor_103129, Mouse strain C57BL/6J (56 days, male) 4.7
70566163 Antisense, RP_050628_02_D11, Mouse strain C57BL/6J (56 days, male) 0.1
1132 Sense, RPS_Baylor_37069, Mouse strain C57BL/6J (56 days, male) 0.0
73931419 Antisense, RP_051214_04_E11, Mouse strain C57BL/6J (56 days, male) 0.0

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