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On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.
Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.
If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.
h
m
l
n
Cholangiocytes:
Not detected
Hepatocytes:
Not detected
RNA expressioni
A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.
The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.
Scroll down to view mRNA expression data in more detail.
Consensus:
92.4
nTPM
HPA:
59.8
nTPM
GTEx:
92.4
nTPM
FANTOM5:
102.9
Scaled Tags Per Million
LIVER - Antibody stainingi
Antibody staining in the annotated cell types in the current human tissue is reported as not detected, low, medium, or high, based on conventional immunohistochemistry profiling in selected tissues. This score is based on the combination of the staining intensity and fraction of stained cells.
Each image is clickable and will lead to virtual microscopy that enables deeper exploration of all samples and also displays staining intensity scores, fraction scores and subcellular localization as well as patient and tissue information for each sample.
Antibody HPA000261
Antibody HPA009066
Antibody HPA047089
Antibody HPA053624
Antibody CAB017698
Cholangiocytes
Not detected
Not detected
Low
Not detected
Not detected
Hepatocytes
Not detected
Not detected
Medium
Low
Not detected
LIVER - HPA RNA-seqi
The RNA-seq details section shows detailed information about the individual samples used for the transcript profiling and results of the RNA-seq analysis.
Information about each individual sample is listed below, including gender, age, a tissue section image and estimated fractions of cell types. nTPM (normalized transcripts per million) values give a quantification of the gene abundance which is comparable between different genes and samples.
Average nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
59.8
Female, age 60
Liver sample 21 nTPM: 64.2
Male, age 54
Liver sample 23 nTPM: 81.7
Cell types%
Hepatocytes:
80
Fibroblasts:
15
Other cell types:
5
Male, age 74
Liver sample 24 nTPM: 61
Cell types%
Hepatocytes:
85
Fibroblasts:
5
Other cell types:
10
Female, age 62
Liver sample 350 nTPM: 40.8
Cell types%
Hepatocytes:
70
Fibroblasts:
10
Other cell types:
20
Male, age 78
Liver sample 351 nTPM: 73.8
Cell types%
Hepatocytes:
75
Fibroblasts:
5
Other cell types:
20
Male, age 53
Liver sample 352 nTPM: 46.1
Cell types%
Hepatocytes:
80
Fibroblasts:
5
Other cell types:
15
Male, age 77
Liver sample 353 nTPM: 96
Cell types%
Hepatocytes:
75
Fibroblasts:
5
Other cell types:
20
Female, age 72
Liver sample 359 nTPM: 29.8
Cell types%
Hepatocytes:
50
Fibroblasts:
10
Other cell types:
40
Male, age 70
Liver sample 367 nTPM: 58.2
Cell types%
Hepatocytes:
65
Fibroblasts:
10
Other cell types:
25
Female, age 23
Liver sample 396 nTPM: 46.5
Cell types%
Hepatocytes:
70
Fibroblasts:
5
Other cell types:
25
LIVER - GTEx RNA-seqi
RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.
Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
92.4
GTEx sample id
Sample description
nTPM
Liver Average nTPM: 92.4
Samples: 226
Max nTPM: 338.3
Min nTPM: 32.7
Std nTPM: 42.6
Median nTPM: 80.6
GTEX-ZAB4-0826-SM-5LU9D
40-49 years, male
338.3
GTEX-O5YT-0826-SM-3TW8N
20-29 years, male
270.9
GTEX-1497J-0726-SM-5Q5D1
60-69 years, male
262.5
GTEX-1IKK5-0326-SM-C1YPY
60-69 years, male
240.7
GTEX-QDVN-0826-SM-48TZ2
50-59 years, male
222.3
GTEX-1LGRB-0626-SM-CNNQH
50-59 years, female
214.5
GTEX-Q734-0326-SM-48U15
40-49 years, female
196.0
GTEX-YB5E-0326-SM-5IFHU
40-49 years, male
187.5
GTEX-ZVP2-0626-SM-51MSO
50-59 years, male
184.4
GTEX-11EQ9-0526-SM-5A5JZ
30-39 years, male
174.4
GTEX-ZYY3-0626-SM-5NQ6W
60-69 years, female
171.2
GTEX-132AR-0426-SM-5IFH8
50-59 years, female
169.4
GTEX-QEL4-1226-SM-447A4
50-59 years, male
166.5
GTEX-12WSI-0226-SM-5GCNA
50-59 years, male
166.2
GTEX-11GSP-0626-SM-5986T
60-69 years, female
163.4
GTEX-14BIL-1326-SM-79OMR
50-59 years, male
158.6
GTEX-13FTW-1126-SM-5J2NV
40-49 years, male
156.3
GTEX-1ICG6-1026-SM-B2LY6
70-79 years, female
153.1
GTEX-14PJO-1726-SM-68719
60-69 years, male
151.1
GTEX-14PHX-0526-SM-664NW
50-59 years, male
150.4
GTEX-1JMLX-1326-SM-CXZJO
50-59 years, male
143.7
GTEX-1E2YA-1226-SM-7MGY3
50-59 years, male
142.2
GTEX-RTLS-1326-SM-46MUN
60-69 years, female
138.7
GTEX-1QPFJ-1126-SM-E9U5V
30-39 years, female
137.5
GTEX-UTHO-2426-SM-4JBHD
60-69 years, male
135.8
GTEX-15DYW-1326-SM-6LPIV
60-69 years, female
135.5
GTEX-REY6-1226-SM-48FDR
60-69 years, male
132.1
GTEX-1NV8Z-1626-SM-DPRYT
60-69 years, male
131.7
GTEX-145MO-2326-SM-5NQ9K
60-69 years, male
131.5
GTEX-1EN7A-2026-SM-7MGY4
40-49 years, male
131.5
GTEX-147JS-1126-SM-5RQIW
60-69 years, male
131.2
GTEX-147GR-1326-SM-7IGLB
60-69 years, male
131.1
GTEX-1GF9W-0826-SM-7MKHI
60-69 years, male
131.1
GTEX-147F4-1426-SM-5LUA8
50-59 years, male
130.5
GTEX-ZTPG-1426-SM-51MT3
20-29 years, female
130.5
GTEX-X261-1726-SM-4PQYT
50-59 years, male
125.4
GTEX-13113-1326-SM-5GCOI
60-69 years, female
124.3
GTEX-11DXZ-0126-SM-5EGGY
50-59 years, male
124.1
GTEX-131YS-1626-SM-5HL6C
60-69 years, female
123.4
GTEX-1R9JW-0826-SM-DPRZJ
30-39 years, female
123.4
GTEX-12WSD-1426-SM-5GCN9
60-69 years, female
123.1
GTEX-1HCVE-1526-SM-B2LWW
50-59 years, male
121.6
GTEX-13N11-0926-SM-5IJG2
50-59 years, female
120.7
GTEX-1HB9E-0626-SM-AHZ4K
50-59 years, male
120.2
GTEX-ZVT4-0626-SM-5E45T
50-59 years, female
118.6
GTEX-WYVS-1926-SM-4PQZ2
40-49 years, female
117.8
GTEX-WK11-1326-SM-4OOSI
50-59 years, male
114.9
GTEX-1AX8Z-1026-SM-7189R
60-69 years, male
114.4
GTEX-1HT8W-0826-SM-C1YRJ
30-39 years, male
113.9
GTEX-Y5LM-0426-SM-4VBRO
40-49 years, female
113.2
GTEX-1LH75-0926-SM-EAZ5C
50-59 years, female
113.2
GTEX-1MJIX-0726-SM-DPRYP
40-49 years, male
113.1
GTEX-YEC4-0826-SM-5P9FV
40-49 years, male
112.4
GTEX-1JJEA-1526-SM-CNNPK
60-69 years, male
111.5
GTEX-18D9B-1526-SM-7KFRK
60-69 years, male
111.2
GTEX-WFON-1726-SM-4LVMQ
40-49 years, male
111.0
GTEX-1GZ4I-1526-SM-9OSW9
50-59 years, male
109.6
GTEX-14E7W-1526-SM-6871X
70-79 years, male
107.3
GTEX-12WSM-0726-SM-5GCOW
60-69 years, male
106.2
GTEX-17HII-1026-SM-7IGLY
50-59 years, male
105.9
GTEX-1C6VQ-1626-SM-79OO1
50-59 years, male
104.3
GTEX-U3ZN-0226-SM-3DB8D
30-39 years, female
104.2
GTEX-1KAFJ-0726-SM-CXZKF
50-59 years, male
104.0
GTEX-12KS4-1326-SM-5LUB3
30-39 years, male
103.3
GTEX-13SLX-1226-SM-5S2Q6
50-59 years, female
102.0
GTEX-11WQC-0726-SM-5EQMR
60-69 years, male
101.2
GTEX-ZAB5-0426-SM-5CVMI
50-59 years, male
100.8
GTEX-ZF29-2026-SM-DNZYW
60-69 years, female
100.6
GTEX-17HGU-1826-SM-7IGQM
50-59 years, male
100.2
GTEX-12WSG-0626-SM-5FQTQ
50-59 years, female
99.2
GTEX-18A7A-1526-SM-72D69
50-59 years, female
99.2
GTEX-15RJE-1126-SM-6LPI5
40-49 years, male
98.9
GTEX-15RJ7-2026-SM-6LPJ4
40-49 years, male
98.8
GTEX-148VI-0626-SM-5TDDH
60-69 years, female
98.2
GTEX-11ZTS-1426-SM-5EQMM
60-69 years, female
97.3
GTEX-X4EP-1026-SM-4QAS5
60-69 years, female
96.9
GTEX-11DXY-0526-SM-5EGGQ
60-69 years, male
96.7
GTEX-13OW6-2626-SM-5IFF2
50-59 years, male
95.5
GTEX-17MF6-1126-SM-7DUFS
40-49 years, male
95.5
GTEX-T6MN-1226-SM-3NMA5
50-59 years, male
95.1
GTEX-1QCLZ-1226-SM-EAZ49
60-69 years, female
95.1
GTEX-1F75A-1626-SM-9JGGT
50-59 years, male
94.5
GTEX-1GN73-1126-SM-9OSW5
60-69 years, male
94.4
GTEX-ZVT3-1626-SM-5GU66
60-69 years, female
94.3
GTEX-131XE-0326-SM-5LZVO
50-59 years, male
93.3
GTEX-1JJ6O-0826-SM-CXZJL
60-69 years, male
91.8
GTEX-1399R-1226-SM-5P9GF
30-39 years, male
90.6
GTEX-1212Z-0226-SM-59HLF
60-69 years, male
90.2
GTEX-1269C-0626-SM-5FQSS
60-69 years, female
90.0
GTEX-ZZPU-0426-SM-5GZYH
50-59 years, female
89.6
GTEX-RM2N-1926-SM-48FCU
50-59 years, male
89.4
GTEX-14753-1626-SM-5NQ9L
60-69 years, male
88.7
GTEX-1A8G7-1126-SM-731ED
60-69 years, male
88.7
GTEX-P78B-1326-SM-3P611
40-49 years, female
88.4
GTEX-X3Y1-2726-SM-4PQZH
40-49 years, male
87.6
GTEX-15SHU-1826-SM-7KUKS
40-49 years, female
87.1
GTEX-18A66-2026-SM-7189C
60-69 years, male
87.0
GTEX-146FH-1526-SM-5NQBU
50-59 years, female
86.7
GTEX-17F96-1226-SM-79OK2
70-79 years, male
86.6
GTEX-14AS3-0126-SM-5Q5F4
40-49 years, female
85.7
GTEX-13FLV-0326-SM-5N9DJ
50-59 years, male
85.4
GTEX-Y111-0726-SM-EYYVM
50-59 years, male
85.4
GTEX-13PVR-0126-SM-5S2PY
60-69 years, female
85.1
GTEX-RNOR-1426-SM-48FDJ
50-59 years, female
85.0
GTEX-1B933-1226-SM-731DW
50-59 years, female
83.8
GTEX-S4Z8-0526-SM-4AD4T
60-69 years, male
83.4
GTEX-11ZVC-0726-SM-5FQT9
50-59 years, female
83.3
GTEX-WY7C-0726-SM-4ONCB
50-59 years, male
82.8
GTEX-R53T-0326-SM-48FEC
50-59 years, female
82.3
GTEX-1HBPH-2626-SM-A96TV
40-49 years, female
81.9
GTEX-13QJC-0726-SM-5RQJK
60-69 years, female
81.4
GTEX-XBEC-1526-SM-4AT68
50-59 years, male
80.9
GTEX-1KD5A-1226-SM-CXZK7
50-59 years, male
80.7
GTEX-S33H-1626-SM-4AD68
30-39 years, male
80.4
GTEX-QV44-0326-SM-C1YQX
50-59 years, male
80.3
GTEX-PX3G-0826-SM-48TZS
20-29 years, female
80.1
GTEX-1CAMQ-1426-SM-7MKFL
40-49 years, male
79.7
GTEX-1GN2E-0926-SM-9WPOH
60-69 years, male
79.7
GTEX-OIZF-0826-SM-3MJGO
60-69 years, male
79.4
GTEX-11TT1-1726-SM-5EQLJ
20-29 years, male
79.1
GTEX-139YR-0226-SM-5IFEM
50-59 years, male
78.1
GTEX-WVLH-2126-SM-EYYWD
50-59 years, male
77.9
GTEX-1B8L1-0726-SM-7P8RT
60-69 years, male
77.8
GTEX-1RQEC-1126-SM-EAZ5E
60-69 years, male
77.8
GTEX-1B996-1426-SM-7EPIA
60-69 years, male
77.3
GTEX-1B8SG-1326-SM-79ONT
50-59 years, male
77.0
GTEX-1BAJH-1526-SM-7RHGI
70-79 years, male
77.0
GTEX-X4EO-1126-SM-4QARQ
60-69 years, female
76.9
GTEX-1I1HK-1126-SM-AHZ2L
60-69 years, male
76.7
GTEX-UPK5-1426-SM-4JBHH
40-49 years, male
76.4
GTEX-ZF2S-3026-SM-4WWCH
50-59 years, female
76.2
GTEX-ZEX8-0826-SM-4WKHK
50-59 years, male
76.1
GTEX-1399T-0826-SM-5IFES
60-69 years, male
76.0
GTEX-132NY-0926-SM-5P9G3
60-69 years, male
75.7
GTEX-14E1K-0326-SM-5S2PE
50-59 years, male
75.5
GTEX-ZPU1-0826-SM-57WG2
40-49 years, male
75.5
GTEX-14DAQ-1726-SM-5S2R2
60-69 years, female
75.1
GTEX-18A6Q-2026-SM-718AQ
60-69 years, male
74.8
GTEX-1CB4F-1726-SM-7MGXH
60-69 years, male
74.5
GTEX-Y5V5-0926-SM-4VBPZ
60-69 years, female
74.4
GTEX-Z9EW-0426-SM-5CVM9
40-49 years, male
74.2
GTEX-S32W-1926-SM-4AD63
50-59 years, female
73.8
GTEX-1GF9V-1226-SM-7MKGY
60-69 years, male
73.2
GTEX-1A8FM-1226-SM-7IGMD
50-59 years, female
73.1
GTEX-145MF-0826-SM-5QGQA
50-59 years, male
72.8
GTEX-1QP66-0226-SM-DPRXS
50-59 years, male
72.7
GTEX-14JG1-1626-SM-664NH
40-49 years, male
72.3
GTEX-Q2AG-1126-SM-48U1P
40-49 years, female
72.2
GTEX-12696-0826-SM-5EGGE
60-69 years, male
72.0
GTEX-1ICLY-1526-SM-C1YS4
50-59 years, male
72.0
GTEX-12WSL-0226-SM-5CVMJ
50-59 years, male
71.7
GTEX-1I1GR-1526-SM-CNNQE
60-69 years, male
71.4
GTEX-11ZUS-2526-SM-59872
30-39 years, male
71.3
GTEX-139TU-0826-SM-5IJFG
60-69 years, male
70.9
GTEX-13NZ9-1326-SM-5MR3V
50-59 years, male
70.9
GTEX-1GN1U-0926-SM-9WPPY
50-59 years, female
70.7
GTEX-1KANB-2226-SM-DHXJW
50-59 years, male
70.6
GTEX-YECK-1926-SM-4W21H
60-69 years, male
70.2
GTEX-ZYT6-0626-SM-5E45V
30-39 years, male
70.2
GTEX-1H11D-0826-SM-9OSWB
40-49 years, male
70.2
GTEX-145LU-1326-SM-5LU9N
50-59 years, male
69.7
GTEX-1EH9U-1126-SM-7IGLU
60-69 years, male
69.5
GTEX-13N2G-0926-SM-5IFGJ
60-69 years, male
69.4
GTEX-14XAO-0226-SM-68728
60-69 years, female
69.2
GTEX-13NYB-1026-SM-5IFH3
40-49 years, male
68.8
GTEX-1HBPI-1026-SM-AHZ4N
50-59 years, male
68.1
GTEX-1AMFI-0826-SM-731DV
50-59 years, female
68.0
GTEX-OOBJ-0826-SM-3NB2K
60-69 years, male
67.9
GTEX-144GM-1326-SM-5LU5E
20-29 years, male
67.5
GTEX-1PBJJ-0626-SM-DPRYO
30-39 years, male
66.2
GTEX-VUSG-0126-SM-4KL1X
50-59 years, male
66.1
GTEX-13O1R-2026-SM-5KM3N
60-69 years, male
65.9
GTEX-11OF3-0726-SM-5BC4Z
60-69 years, male
65.8
GTEX-11NV4-1326-SM-5HL6V
60-69 years, male
65.0
GTEX-1B932-1426-SM-793AN
40-49 years, female
65.0
GTEX-U8XE-1526-SM-4E3HT
30-39 years, male
64.2
GTEX-17HHE-0126-SM-79398
50-59 years, male
63.8
GTEX-1EWIQ-0726-SM-7MKFW
70-79 years, female
63.5
GTEX-13VXU-0926-SM-5IFFH
50-59 years, male
63.3
GTEX-13PVQ-1526-SM-5IFEQ
50-59 years, male
63.2
GTEX-139TS-1426-SM-5IFJD
60-69 years, male
63.1
GTEX-1EKGG-1226-SM-7IGNO
60-69 years, male
62.8
GTEX-13O3O-1826-SM-5IFGW
60-69 years, female
62.4
GTEX-14A5I-1726-SM-5QGQ5
50-59 years, female
62.0
GTEX-18465-1626-SM-7LG6N
50-59 years, male
61.1
GTEX-13X6J-1826-SM-5TDCT
50-59 years, male
59.8
GTEX-11NUK-1226-SM-5P9GM
50-59 years, male
59.6
GTEX-15ER7-1826-SM-6LLI7
20-29 years, female
59.2
GTEX-12ZZZ-1326-SM-59HKW
60-69 years, male
58.6
GTEX-17EVP-1026-SM-7IGOZ
40-49 years, male
58.5
GTEX-RU72-1426-SM-46MUF
50-59 years, female
57.6
GTEX-1J8EW-1626-SM-C1YQ8
60-69 years, female
57.0
GTEX-TKQ2-1726-SM-4DXUP
50-59 years, male
56.6
GTEX-YFC4-1526-SM-5IFJS
40-49 years, female
56.6
GTEX-1KD4Q-1526-SM-D4P3L
40-49 years, male
56.5
GTEX-13FTZ-0726-SM-5IFFY
60-69 years, male
56.3
GTEX-131XH-0626-SM-5LZWH
50-59 years, male
55.5
GTEX-13NZB-0626-SM-5IFH6
30-39 years, male
55.3
GTEX-1IKJJ-1526-SM-C1YSC
60-69 years, male
55.3
GTEX-SJXC-1226-SM-4DM78
60-69 years, male
54.0
GTEX-QESD-2026-SM-447BI
20-29 years, male
53.3
GTEX-1QP6S-1326-SM-DPRZ8
40-49 years, male
52.4
GTEX-13112-1426-SM-5EGH8
50-59 years, male
52.3
GTEX-RWSA-1426-SM-47JXA
40-49 years, male
51.8
GTEX-1GF9X-0426-SM-7MKHN
40-49 years, female
50.5
GTEX-11TUW-1726-SM-5BC5C
60-69 years, male
49.2
GTEX-1KWVE-0326-SM-EV7AF
30-39 years, male
49.2
GTEX-P44G-1126-SM-3NM9D
30-39 years, male
48.2
GTEX-WQUQ-1926-SM-4OOSA
60-69 years, male
47.9
GTEX-144GL-1426-SM-79OMA
50-59 years, male
47.5
GTEX-14C38-1526-SM-5RQJ7
50-59 years, male
47.5
GTEX-1PIIG-1326-SM-EXOIR
30-39 years, male
46.9
GTEX-1K9T9-0726-SM-CXZJZ
50-59 years, female
45.8
GTEX-RN64-1826-SM-48FDV
50-59 years, male
45.6
GTEX-1CB4J-0726-SM-7IGN8
60-69 years, male
43.9
GTEX-X4XY-1626-SM-46MVN
60-69 years, male
43.7
GTEX-O5YV-0726-SM-EV798
60-69 years, female
43.6
GTEX-1HCU7-1726-SM-B2LX9
50-59 years, male
42.9
GTEX-WZTO-0626-SM-4PQYY
40-49 years, male
42.2
GTEX-1AX9I-1626-SM-72D5D
60-69 years, male
42.1
GTEX-15SZO-1226-SM-6LPIP
50-59 years, male
41.3
GTEX-QEG4-1826-SM-CKZN9
30-39 years, male
40.8
GTEX-1S5VW-1826-SM-EAZ53
60-69 years, male
40.7
GTEX-XXEK-1126-SM-4BRUX
50-59 years, male
38.9
GTEX-1A32A-0826-SM-72D5C
50-59 years, female
33.6
GTEX-1S82Y-1026-SM-EV7BJ
40-49 years, male
32.7
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LIVER - FANTOM5 CAGEi
RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.
Max subtype Scaled Tags Per Millioni
Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.
The Human Protein Atlas project is funded
