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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:155.0 nTPM
HPA Brain:259.0 nTPM
GTEx:155.0 nTPM
FANTOM5:285.7 Scaled Tags Per Million
Pig:457.8 nTPM
Mouse:133.5 nTPM
Allen mouse:3.0 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

259.0
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 148.0
2019 Male, age 18, unknown 202.7
2411 Female, age 72, unknown 168.7
2666 Male, age 74, left hemisphere 164.6
2219 Male, age 76, both hemispheres 163.0
2828 Female, age 72, unknown 151.3
1830 Male, age 51, unknown 138.5
1833 Male, age 53, unknown 136.5
1870 Female, age 42, unknown 129.1
1827 Male, age 72, unknown 123.7
2586 Male, age 75, left hemisphere 102.0
Dorsal raphe nucleus
nTPM: 174.4
2047 Male, age 72, unknown 198.7
2750 Male, age 76, both hemispheres 198.6
2298 Female, age 72, unknown 186.7
1828 Male, age 53, unknown 165.1
2016 Female, age 72, unknown 122.8
Inferior colliculus
nTPM: 127.7
2097 Female, age 72, unknown 141.5
1890 Male, age 53, unknown 141.4
2849 Male, age 72, unknown 116.7
1848 Female, age 42, unknown 111.4
Median raphe nucleus
nTPM: 259.0
2220 Male, age 76, midline 259.0
Periaquaductal grey, anterior
nTPM: 138.0
1795 Male, age 51, unknown 150.7
1947 Male, age 18, unknown 134.5
2502 Female, age 75, unknown 128.9
Periaquaductal grey, dorsal
nTPM: 128.4
2850 Male, age 76, both hemispheres 165.9
2464 Female, age 72, unknown 119.9
1831 Male, age 72, unknown 116.0
1840 Male, age 53, unknown 111.6
Periaquaductal grey, lateral
nTPM: 145.4
2272 Male, age 74, both hemispheres 199.2
2140 Male, age 76, both hemispheres 141.4
2053 Male, age 18, unknown 95.6
Pretectal area
nTPM: 163.2
2007 Male, age 72, unknown 217.0
1817 Female, age 42, unknown 212.8
1944 Female, age 72, unknown 190.6
1815 Male, age 53, unknown 188.8
2273 Male, age 74, both hemispheres 174.2
1816 Male, age 51, unknown 163.8
2667 Female, age 75, unknown 162.3
2224 Female, age 72, unknown 144.0
2407 Male, age 75, both hemispheres 130.7
2825 Male, age 18, unknown 106.3
2316 Male, age 76, right hemisphere 105.0
Red nucleus
nTPM: 148.1
2785 Male, age 18, unknown 204.0
1865 Male, age 51, unknown 165.9
2725 Female, age 75, unknown 160.1
2823 Male, age 76, right hemisphere 157.9
1904 Male, age 53, unknown 152.8
2503 Female, age 72, unknown 148.6
1954 Female, age 42, unknown 146.4
2769 Male, age 72, unknown 135.7
2227 Male, age 72, unknown 133.5
1821 Female, age 72, unknown 130.4
2588 Male, age 74, left hemisphere 125.4
2584 Male, age 75, left hemisphere 116.8
Substantia nigra
nTPM: 217.4
1916 Female, age 42, unknown 355.1
1851 Male, age 51, unknown 259.2
2699 Male, age 18, unknown 249.1
1941 Male, age 53, unknown 240.6
2241 Male, age 72, unknown 214.3
1889 Female, age 72, unknown 207.3
2409 Female, age 72, unknown 184.9
2665 Male, age 74, both hemispheres 180.6
2590 Female, age 75, unknown 147.7
2583 Male, age 75, right hemisphere 135.0
Superior colliculus
nTPM: 141.3
2668 Female, age 75, unknown 189.0
2087 Female, age 72, unknown 166.1
2587 Male, age 74, left hemisphere 162.3
1913 Female, age 42, unknown 154.4
1995 Male, age 72, unknown 142.7
2261 Male, age 18, unknown 134.2
1796 Male, age 53, unknown 132.2
1839 Male, age 51, unknown 111.8
2664 Male, age 75, both hemispheres 111.6
1895 Male, age 76, right hemisphere 108.7
Ventral tegmental area
nTPM: 195.9
1915 Female, age 42, unknown 233.4
2218 Male, age 76, both hemispheres 232.5
2410 Female, age 72, unknown 217.3
2223 Female, age 72, unknown 171.0
2021 Male, age 53, unknown 161.5
1942 Male, age 51, unknown 159.7

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

155.0
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 155.0
Samples: 139

Max nTPM: 289.3
Min nTPM: 59.0
Std nTPM: 43.8
Median nTPM: 147.9
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 289.3
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 272.2
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 254.7
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 247.6
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 241.9
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 238.2
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 236.0
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 235.4
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 228.7
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 226.9
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 222.6
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 221.9
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 220.0
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 218.7
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 217.7
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 216.3
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 216.0
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 215.8
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 208.3
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 207.1
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 206.5
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 206.1
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 205.6
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 202.2
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 199.4
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 197.8
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 195.2
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 193.1
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 193.0
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 191.3
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 189.4
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 189.0
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 188.9
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 186.1
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 185.9
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 185.8
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 183.7
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 181.4
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 180.5
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 180.2
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 177.8
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 177.1
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 176.7
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 174.4
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 174.1
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 170.3
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 168.8
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 166.5
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 162.2
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 161.7
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 159.1
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 158.6
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 155.7
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 154.8
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 154.6
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 154.5
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 153.5
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 152.9
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 152.6
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 151.2
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 151.1
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 150.7
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 150.7
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 150.4
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 150.1
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 149.3
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 149.2
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 148.9
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 148.6
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 147.9
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 145.4
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 144.2
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 143.9
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 143.5
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 143.3
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 142.9
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 142.8
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 142.7
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 142.6
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 141.9
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 141.6
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 140.9
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 140.7
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 139.8
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 137.5
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 136.5
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 136.2
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 135.8
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 135.0
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 133.9
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 132.7
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 131.9
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 131.5
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 130.8
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 130.0
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 129.8
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 129.7
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 129.5
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 129.3
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 129.3
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 128.3
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 127.4
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 126.9
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 126.8
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 126.6
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 126.6
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 126.0
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 125.1
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 124.8
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 124.5
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 123.7
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 122.4
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 121.9
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 120.0
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 117.6
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 115.7
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 115.2
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 115.2
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 111.5
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 109.5
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 107.2
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 107.0
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 106.8
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 103.5
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 103.1
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 101.6
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 100.7
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 98.4
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 96.0
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 95.0
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 94.4
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 90.9
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 90.3
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 87.3
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 86.2
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 86.1
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 85.0
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 71.2
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 59.0
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

285.7
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 285.7
FF:10158-103A5 76 years, female 285.7

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

457.8
Pig sample Sample description nTPM
Substantia nigra
nTPM: 457.9
Samples: 4

Max nTPM: 626.5
Min nTPM: 319.6
Sample A Female 513.0
Sample B Female 319.6
Sample C Male 372.3
Sample D Male 626.5
Midbrain
nTPM: 418.5
Samples: 4

Max nTPM: 602.8
Min nTPM: 296.3
Sample A Female 602.8
Sample B Female 458.9
Sample C Male 315.9
Sample D Male 296.3
Periaqueductal gray
nTPM: 332.7
Samples: 3

Max nTPM: 356.2
Min nTPM: 309.2
Sample B Female 309.2
Sample C Male 332.8
Sample D Male 356.2
Superior colliculi
nTPM: 406.9
Samples: 4

Max nTPM: 531.6
Min nTPM: 213.7
Sample A Female 531.6
Sample B Female 213.7
Sample C Male 367.9
Sample D Male 514.5

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

133.5
Mouse sample Sample description nTPM
Midbrain
nTPM: 133.5
Samples: 4

Max nTPM: 144.7
Min nTPM: 124.1
Sample A Male 144.7
Sample B Male 124.1
Sample C Female 126.8
Sample D Female 138.4

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

3.0
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 3.0
69873708 Antisense, RP_050512_01_G10, Mouse strain C57BL/6J (56 days, male) 3.0

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