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TISSUE MIDBRAIN Show tissue menu
ADIPOSE TISSUE ADRENAL GLAND AMYGDALA APPENDIX BASAL GANGLIA BONE MARROW BREAST CEREBELLUM CEREBRAL CORTEX CERVIX CHOROID PLEXUS COLON DUODENUM
ENDOMETRIUM EPIDIDYMIS ESOPHAGUS FALLOPIAN TUBE GALLBLADDER HEART MUSCLE HIPPOCAMPAL FORMATION HYPOTHALAMUS KIDNEY LIVER LUNG LYMPH NODE MIDBRAIN
OVARY PANCREAS PARATHYROID GLAND PITUITARY GLAND PLACENTA PROSTATE RECTUM RETINA SALIVARY GLAND SEMINAL VESICLE SKELETAL MUSCLE SKIN SMALL INTESTINE
SMOOTH MUSCLE SPINAL CORD SPLEEN STOMACH TESTIS THYMUS THYROID GLAND TONGUE TONSIL URINARY BLADDER VAGINA
Dictionary
Tissue proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:961.6 nTPM
HPA Brain:381.8 nTPM
GTEx:961.6 nTPM
FANTOM5:12.1 Scaled Tags Per Million
Pig:360.5 nTPM
Mouse:377.5 nTPM
Allen mouse:11.2 Expression energy

MIDBRAIN - Annotated protein expression
Pending normal tissue analysis

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

381.8
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 349.3
2666 Male, age 74, left hemisphere 412.9
2411 Female, age 72, unknown 394.1
1870 Female, age 42, unknown 375.5
1830 Male, age 51, unknown 351.3
2828 Female, age 72, unknown 349.3
1827 Male, age 72, unknown 342.9
2586 Male, age 75, left hemisphere 339.9
2019 Male, age 18, unknown 330.4
1833 Male, age 53, unknown 325.4
2219 Male, age 76, both hemispheres 271.3
Dorsal raphe nucleus
nTPM: 348.1
2298 Female, age 72, unknown 387.0
2016 Female, age 72, unknown 371.3
2750 Male, age 76, both hemispheres 367.6
1828 Male, age 53, unknown 326.3
2047 Male, age 72, unknown 288.4
Inferior colliculus
nTPM: 328.2
1890 Male, age 53, unknown 341.9
2097 Female, age 72, unknown 341.1
2849 Male, age 72, unknown 319.3
1848 Female, age 42, unknown 310.6
Median raphe nucleus
nTPM: 319.2
2220 Male, age 76, midline 319.2
Periaquaductal grey, anterior
nTPM: 349.9
2502 Female, age 75, unknown 424.8
1947 Male, age 18, unknown 321.8
1795 Male, age 51, unknown 303.0
Periaquaductal grey, dorsal
nTPM: 336.8
1840 Male, age 53, unknown 372.1
2464 Female, age 72, unknown 349.9
1831 Male, age 72, unknown 341.0
2850 Male, age 76, both hemispheres 284.2
Periaquaductal grey, lateral
nTPM: 310.3
2053 Male, age 18, unknown 347.6
2272 Male, age 74, both hemispheres 303.9
2140 Male, age 76, both hemispheres 279.5
Pretectal area
nTPM: 319.1
2224 Female, age 72, unknown 359.6
2316 Male, age 76, right hemisphere 349.5
2825 Male, age 18, unknown 345.2
1815 Male, age 53, unknown 343.4
1817 Female, age 42, unknown 324.5
2007 Male, age 72, unknown 317.8
2273 Male, age 74, both hemispheres 307.5
1816 Male, age 51, unknown 304.9
1944 Female, age 72, unknown 290.5
2407 Male, age 75, both hemispheres 289.9
2667 Female, age 75, unknown 277.8
Red nucleus
nTPM: 364.5
2503 Female, age 72, unknown 445.5
1821 Female, age 72, unknown 410.2
1865 Male, age 51, unknown 389.8
1904 Male, age 53, unknown 377.3
2588 Male, age 74, left hemisphere 363.9
2584 Male, age 75, left hemisphere 362.5
2725 Female, age 75, unknown 359.7
2227 Male, age 72, unknown 353.4
2769 Male, age 72, unknown 349.1
1954 Female, age 42, unknown 328.4
2785 Male, age 18, unknown 319.4
2823 Male, age 76, right hemisphere 314.5
Substantia nigra
nTPM: 381.8
2665 Male, age 74, both hemispheres 443.5
2699 Male, age 18, unknown 441.5
1851 Male, age 51, unknown 436.1
2241 Male, age 72, unknown 416.0
2409 Female, age 72, unknown 390.5
1916 Female, age 42, unknown 378.9
2590 Female, age 75, unknown 367.2
1889 Female, age 72, unknown 327.4
1941 Male, age 53, unknown 325.3
2583 Male, age 75, right hemisphere 291.9
Superior colliculus
nTPM: 356.1
2587 Male, age 74, left hemisphere 433.4
1995 Male, age 72, unknown 421.1
1913 Female, age 42, unknown 390.8
1839 Male, age 51, unknown 360.4
1796 Male, age 53, unknown 342.8
2668 Female, age 75, unknown 342.5
2664 Male, age 75, both hemispheres 333.1
1895 Male, age 76, right hemisphere 324.7
2261 Male, age 18, unknown 318.5
2087 Female, age 72, unknown 293.2
Ventral tegmental area
nTPM: 371.5
1915 Female, age 42, unknown 411.3
2223 Female, age 72, unknown 399.2
2021 Male, age 53, unknown 386.4
2410 Female, age 72, unknown 375.0
1942 Male, age 51, unknown 344.7
2218 Male, age 76, both hemispheres 312.2

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

961.6
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 961.6
Samples: 139

Max nTPM: 3103.8
Min nTPM: 374.6
Std nTPM: 377.0
Median nTPM: 879.1
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 3103.8
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 2249.0
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 1986.7
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 1842.3
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 1703.4
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 1602.3
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 1585.3
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 1579.2
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 1541.0
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 1510.7
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 1491.7
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 1470.7
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 1465.1
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 1451.4
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 1433.2
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 1429.9
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 1410.7
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 1388.0
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 1322.7
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 1316.3
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 1296.8
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 1277.0
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 1268.9
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 1266.0
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 1262.9
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 1204.9
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 1203.8
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 1178.1
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 1176.5
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 1176.1
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 1157.4
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 1154.3
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 1151.7
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 1151.1
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 1150.1
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 1147.5
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 1115.3
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 1109.4
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 1105.8
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 1102.9
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 1098.8
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 1092.2
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 1067.8
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 1065.4
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 1064.9
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 1046.6
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 1041.4
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 1036.7
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 1033.8
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 1033.6
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 1032.0
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 999.9
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 987.1
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 983.3
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 978.4
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 973.4
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 968.4
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 967.0
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 963.6
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 935.0
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 932.3
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 929.3
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 926.5
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 921.3
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 920.2
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 918.7
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 915.9
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 897.3
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 881.3
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 879.1
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 869.2
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 868.4
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 867.9
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 861.7
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 858.2
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 855.1
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 849.8
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 840.9
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 832.7
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 826.9
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 820.8
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 815.7
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 812.1
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 801.3
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 800.4
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 798.0
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 797.8
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 790.7
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 786.5
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 786.1
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 785.5
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 771.5
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 756.4
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 750.1
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 747.3
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 744.8
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 741.2
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 737.6
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 734.2
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 713.0
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 711.0
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 709.9
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 703.1
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 700.8
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 698.8
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 698.5
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 685.2
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 680.6
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 676.5
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 675.3
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 670.4
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 667.9
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 667.0
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 655.8
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 641.6
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 640.6
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 609.1
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 605.3
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 602.3
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 600.8
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 599.7
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 585.4
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 584.9
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 583.7
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 580.7
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 575.1
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 569.8
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 565.9
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 560.8
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 560.6
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 555.8
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 551.7
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 549.1
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 531.3
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 527.1
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 526.1
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 500.0
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 426.4
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 374.6
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MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

12.1
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 12.1
FF:10158-103A5 76 years, female 12.1

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

360.5
Pig sample Sample description nTPM
Substantia nigra
nTPM: 353.4
Samples: 4

Max nTPM: 452.7
Min nTPM: 293.5
Sample A Female 452.7
Sample B Female 372.6
Sample C Male 293.5
Sample D Male 294.9
Midbrain
nTPM: 330.4
Samples: 4

Max nTPM: 478.7
Min nTPM: 209.5
Sample A Female 478.7
Sample B Female 369.3
Sample C Male 264.0
Sample D Male 209.5
Periaqueductal gray
nTPM: 265.4
Samples: 3

Max nTPM: 282.5
Min nTPM: 245.0
Sample B Female 282.5
Sample C Male 268.7
Sample D Male 245.0
Superior colliculi
nTPM: 360.5
Samples: 4

Max nTPM: 408.2
Min nTPM: 290.5
Sample A Female 404.6
Sample B Female 408.2
Sample C Male 338.6
Sample D Male 290.5

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

377.5
Mouse sample Sample description nTPM
Midbrain
nTPM: 377.5
Samples: 4

Max nTPM: 405.6
Min nTPM: 359.0
Sample A Male 405.6
Sample B Male 361.7
Sample C Female 359.0
Sample D Female 383.6

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

11.2
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 11.2
69549280 Antisense, RP_050126_02_C10, Mouse strain C57BL/6J (56 days, male) 11.2

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The Human Protein Atlas

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The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg Foundation.


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