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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
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Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:297.6 nTPM
HPA Brain:513.2 nTPM
GTEx:297.6 nTPM
FANTOM5:538.3 Scaled Tags Per Million
Pig:175.2 nTPM
Mouse:128.1 nTPM
Allen mouse:6.0 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

513.2
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 409.8
2019 Male, age 18, unknown 548.7
2411 Female, age 72, unknown 502.8
1870 Female, age 42, unknown 498.4
1830 Male, age 51, unknown 493.7
1833 Male, age 53, unknown 447.9
2828 Female, age 72, unknown 412.0
2586 Male, age 75, left hemisphere 369.4
1827 Male, age 72, unknown 295.5
2219 Male, age 76, both hemispheres 265.4
2666 Male, age 74, left hemisphere 264.2
Dorsal raphe nucleus
nTPM: 324.0
2750 Male, age 76, both hemispheres 484.7
2016 Female, age 72, unknown 338.8
1828 Male, age 53, unknown 317.5
2047 Male, age 72, unknown 241.2
2298 Female, age 72, unknown 237.6
Inferior colliculus
nTPM: 270.7
1890 Male, age 53, unknown 309.2
1848 Female, age 42, unknown 292.3
2097 Female, age 72, unknown 242.9
2849 Male, age 72, unknown 238.2
Median raphe nucleus
nTPM: 337.1
2220 Male, age 76, midline 337.1
Periaquaductal grey, anterior
nTPM: 276.3
2502 Female, age 75, unknown 311.4
1795 Male, age 51, unknown 265.1
1947 Male, age 18, unknown 252.4
Periaquaductal grey, dorsal
nTPM: 265.5
2850 Male, age 76, both hemispheres 338.9
2464 Female, age 72, unknown 294.2
1831 Male, age 72, unknown 261.4
1840 Male, age 53, unknown 167.5
Periaquaductal grey, lateral
nTPM: 345.2
2140 Male, age 76, both hemispheres 399.7
2272 Male, age 74, both hemispheres 335.3
2053 Male, age 18, unknown 300.7
Pretectal area
nTPM: 300.6
2316 Male, age 76, right hemisphere 407.5
2273 Male, age 74, both hemispheres 400.7
2667 Female, age 75, unknown 356.1
1815 Male, age 53, unknown 346.1
2407 Male, age 75, both hemispheres 319.8
1817 Female, age 42, unknown 304.2
2007 Male, age 72, unknown 280.4
2825 Male, age 18, unknown 280.2
2224 Female, age 72, unknown 255.8
1944 Female, age 72, unknown 192.2
1816 Male, age 51, unknown 163.6
Red nucleus
nTPM: 513.2
1904 Male, age 53, unknown 624.0
2769 Male, age 72, unknown 622.1
1865 Male, age 51, unknown 619.0
2227 Male, age 72, unknown 616.4
2785 Male, age 18, unknown 596.2
1954 Female, age 42, unknown 566.7
1821 Female, age 72, unknown 544.1
2503 Female, age 72, unknown 494.3
2823 Male, age 76, right hemisphere 468.9
2588 Male, age 74, left hemisphere 347.9
2584 Male, age 75, left hemisphere 338.8
2725 Female, age 75, unknown 319.6
Substantia nigra
nTPM: 337.6
1851 Male, age 51, unknown 426.9
2583 Male, age 75, right hemisphere 411.2
2590 Female, age 75, unknown 392.7
2409 Female, age 72, unknown 387.3
2699 Male, age 18, unknown 365.5
1916 Female, age 42, unknown 304.8
1889 Female, age 72, unknown 296.9
1941 Male, age 53, unknown 284.1
2241 Male, age 72, unknown 266.2
2665 Male, age 74, both hemispheres 240.1
Superior colliculus
nTPM: 322.8
1995 Male, age 72, unknown 503.5
1913 Female, age 42, unknown 462.9
2587 Male, age 74, left hemisphere 371.7
1839 Male, age 51, unknown 322.2
2668 Female, age 75, unknown 296.0
1796 Male, age 53, unknown 294.0
2664 Male, age 75, both hemispheres 257.4
1895 Male, age 76, right hemisphere 255.5
2087 Female, age 72, unknown 244.8
2261 Male, age 18, unknown 220.0
Ventral tegmental area
nTPM: 411.3
2223 Female, age 72, unknown 585.1
2410 Female, age 72, unknown 434.7
2021 Male, age 53, unknown 389.5
1942 Male, age 51, unknown 361.2
1915 Female, age 42, unknown 354.6
2218 Male, age 76, both hemispheres 343.0

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

297.6
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 297.6
Samples: 139

Max nTPM: 860.2
Min nTPM: 92.1
Std nTPM: 116.5
Median nTPM: 266.0
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 860.2
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 731.7
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 639.1
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 614.4
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 577.6
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 562.3
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 532.9
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 531.0
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 514.7
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 474.4
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 466.7
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 465.2
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 464.0
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 456.2
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 455.9
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 443.0
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 437.3
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 435.0
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 406.5
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 398.1
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 396.7
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 388.7
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 375.9
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 375.3
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 368.6
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 367.4
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 364.3
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 360.7
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 360.7
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 354.8
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 351.0
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 345.1
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 345.1
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 344.1
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 342.5
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 338.0
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 336.5
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 335.3
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 331.3
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 331.3
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 327.6
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 325.0
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 322.7
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 322.6
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 314.0
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 314.0
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 310.2
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 306.0
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 305.9
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 305.5
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 304.8
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 300.8
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 300.4
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 300.0
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 299.2
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 297.6
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 294.2
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 291.5
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 289.6
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 279.9
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 279.2
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 276.1
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 274.1
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 272.7
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 271.6
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 269.3
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 268.3
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 266.8
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 266.6
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 266.0
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 262.0
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 260.7
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 259.8
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 259.2
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 259.2
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 257.6
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 256.6
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 253.1
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 252.4
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 251.2
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 251.2
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 250.1
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 249.4
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 246.9
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 246.1
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 246.1
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 245.9
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 245.5
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 244.0
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 243.8
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 243.3
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 242.5
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 239.8
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 236.4
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 234.1
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 231.7
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 231.6
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 230.4
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 229.7
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 228.5
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 227.6
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 226.0
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 223.9
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 220.4
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 218.4
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 217.0
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 215.0
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 214.7
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 214.1
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 213.8
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 213.5
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 212.0
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 209.8
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 209.1
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 208.4
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 207.2
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 206.5
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 203.2
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 202.3
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 201.3
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 200.8
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 199.6
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 197.3
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 193.6
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 192.7
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 187.2
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 186.9
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 185.8
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 185.8
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 184.4
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 183.0
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 180.4
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 177.6
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 171.2
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 168.6
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 158.3
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 142.9
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 124.6
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 92.1
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

538.3
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 538.3
FF:10158-103A5 76 years, female 538.3

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

175.2
Pig sample Sample description nTPM
Substantia nigra
nTPM: 165.8
Samples: 4

Max nTPM: 208.8
Min nTPM: 117.2
Sample A Female 137.7
Sample B Female 208.8
Sample C Male 117.2
Sample D Male 199.4
Midbrain
nTPM: 168.0
Samples: 4

Max nTPM: 430.0
Min nTPM: 57.5
Sample A Female 430.0
Sample B Female 97.7
Sample C Male 86.8
Sample D Male 57.5
Periaqueductal gray
nTPM: 109.1
Samples: 3

Max nTPM: 124.0
Min nTPM: 94.7
Sample B Female 94.7
Sample C Male 108.5
Sample D Male 124.0
Superior colliculi
nTPM: 175.3
Samples: 4

Max nTPM: 301.1
Min nTPM: 118.7
Sample A Female 161.9
Sample B Female 301.1
Sample C Male 118.7
Sample D Male 119.4

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

128.1
Mouse sample Sample description nTPM
Midbrain
nTPM: 128.1
Samples: 4

Max nTPM: 149.9
Min nTPM: 108.8
Sample A Male 118.2
Sample B Male 108.8
Sample C Female 135.4
Sample D Female 149.9

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

6.0
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 6.0
72081395 Antisense, RP_051017_01_C01, Mouse strain C57BL/6J (56 days, male) 9.8
68444642 Antisense, RP_050111_02_C03, Mouse strain C57BL/6J (56 days, male) 2.2

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