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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
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Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:183.4 nTPM
HPA Brain:274.7 nTPM
GTEx:183.4 nTPM
FANTOM5:240.0 Scaled Tags Per Million
Pig:152.5 nTPM
Mouse:34.8 nTPM
Allen mouse:0.6 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

274.7
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 141.9
2828 Female, age 72, unknown 228.1
2586 Male, age 75, left hemisphere 183.6
2666 Male, age 74, left hemisphere 151.5
2019 Male, age 18, unknown 147.4
1870 Female, age 42, unknown 134.6
2411 Female, age 72, unknown 131.6
1827 Male, age 72, unknown 130.4
1833 Male, age 53, unknown 124.1
1830 Male, age 51, unknown 112.9
2219 Male, age 76, both hemispheres 74.5
Dorsal raphe nucleus
nTPM: 224.4
2016 Female, age 72, unknown 276.8
2298 Female, age 72, unknown 265.3
1828 Male, age 53, unknown 261.0
2047 Male, age 72, unknown 196.8
2750 Male, age 76, both hemispheres 122.2
Inferior colliculus
nTPM: 130.4
2097 Female, age 72, unknown 176.2
2849 Male, age 72, unknown 121.0
1890 Male, age 53, unknown 114.4
1848 Female, age 42, unknown 110.0
Median raphe nucleus
nTPM: 149.4
2220 Male, age 76, midline 149.4
Periaquaductal grey, anterior
nTPM: 163.1
1795 Male, age 51, unknown 214.8
2502 Female, age 75, unknown 148.0
1947 Male, age 18, unknown 126.4
Periaquaductal grey, dorsal
nTPM: 223.3
2850 Male, age 76, both hemispheres 285.0
1840 Male, age 53, unknown 231.5
1831 Male, age 72, unknown 214.0
2464 Female, age 72, unknown 162.6
Periaquaductal grey, lateral
nTPM: 274.7
2140 Male, age 76, both hemispheres 299.8
2272 Male, age 74, both hemispheres 273.8
2053 Male, age 18, unknown 250.6
Pretectal area
nTPM: 201.6
2273 Male, age 74, both hemispheres 437.9
2224 Female, age 72, unknown 242.7
1944 Female, age 72, unknown 215.7
2667 Female, age 75, unknown 195.8
2316 Male, age 76, right hemisphere 179.6
1816 Male, age 51, unknown 177.6
2825 Male, age 18, unknown 170.8
1815 Male, age 53, unknown 169.5
2407 Male, age 75, both hemispheres 164.3
1817 Female, age 42, unknown 148.6
2007 Male, age 72, unknown 115.6
Red nucleus
nTPM: 145.7
2725 Female, age 75, unknown 234.3
2503 Female, age 72, unknown 169.3
1821 Female, age 72, unknown 154.5
2769 Male, age 72, unknown 149.8
2227 Male, age 72, unknown 146.0
2785 Male, age 18, unknown 142.9
2823 Male, age 76, right hemisphere 141.5
1865 Male, age 51, unknown 136.8
1954 Female, age 42, unknown 135.0
1904 Male, age 53, unknown 128.4
2584 Male, age 75, left hemisphere 112.0
2588 Male, age 74, left hemisphere 97.2
Substantia nigra
nTPM: 210.8
2699 Male, age 18, unknown 277.5
1851 Male, age 51, unknown 267.8
1916 Female, age 42, unknown 263.8
2241 Male, age 72, unknown 248.6
2409 Female, age 72, unknown 213.9
1941 Male, age 53, unknown 191.1
2590 Female, age 75, unknown 189.9
2583 Male, age 75, right hemisphere 167.7
1889 Female, age 72, unknown 160.7
2665 Male, age 74, both hemispheres 126.7
Superior colliculus
nTPM: 183.1
1995 Male, age 72, unknown 273.4
2087 Female, age 72, unknown 221.5
1913 Female, age 42, unknown 213.5
2587 Male, age 74, left hemisphere 198.1
1796 Male, age 53, unknown 195.9
2664 Male, age 75, both hemispheres 194.9
2261 Male, age 18, unknown 183.3
1839 Male, age 51, unknown 135.2
2668 Female, age 75, unknown 120.0
1895 Male, age 76, right hemisphere 95.6
Ventral tegmental area
nTPM: 194.9
1915 Female, age 42, unknown 250.8
2021 Male, age 53, unknown 220.0
2410 Female, age 72, unknown 198.6
1942 Male, age 51, unknown 190.0
2223 Female, age 72, unknown 155.7
2218 Male, age 76, both hemispheres 154.2

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

183.4
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 183.4
Samples: 139

Max nTPM: 454.5
Min nTPM: 52.0
Std nTPM: 73.9
Median nTPM: 169.8
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 454.5
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 429.8
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 379.1
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 365.8
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 354.6
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 341.3
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 340.8
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 321.2
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 313.4
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 313.3
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 301.3
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 285.1
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 274.6
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 270.5
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 269.8
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 267.2
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 264.9
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 261.6
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 258.7
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 258.7
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 256.6
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 251.5
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 250.7
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 248.5
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 243.2
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 243.0
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 240.5
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 239.5
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 238.6
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 233.0
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 231.0
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 230.5
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 229.6
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 226.5
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 225.7
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 223.3
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 215.6
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 215.0
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 214.7
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 214.1
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 213.6
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 207.9
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 207.4
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 204.7
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 203.6
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 203.0
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 201.9
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 201.8
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 201.3
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 200.6
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 199.4
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 194.3
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 194.0
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 193.0
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 188.4
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 187.0
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 184.6
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 183.5
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 182.6
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 181.2
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 181.2
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 179.2
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 178.9
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 178.6
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 178.3
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 176.6
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 174.1
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 172.1
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 170.7
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 169.8
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 169.3
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 166.7
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 166.3
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 165.9
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 164.8
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 163.8
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 163.6
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 162.7
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 162.6
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 162.3
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 161.5
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 160.7
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 160.0
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 154.8
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 154.1
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 152.3
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 151.7
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 151.6
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 151.4
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 151.4
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 150.6
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 148.6
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 148.1
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 148.0
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 147.7
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 147.2
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 146.9
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 146.5
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 143.6
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 142.8
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 140.2
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 139.4
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 136.8
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 136.1
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 135.3
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 135.1
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 134.6
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 134.6
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 128.3
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 124.2
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 123.5
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 123.0
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 118.4
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 116.5
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 115.2
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 114.9
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 114.6
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 111.6
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 110.5
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 107.0
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 107.0
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 107.0
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 105.2
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 100.7
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 100.1
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 99.8
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 99.0
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 98.8
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 95.0
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 91.2
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 85.9
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 83.6
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 82.4
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 77.0
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 76.2
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 59.1
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 55.6
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 52.5
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 52.0
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

240.0
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 240.0
FF:10158-103A5 76 years, female 240.0

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

152.5
Pig sample Sample description nTPM
Substantia nigra
nTPM: 136.9
Samples: 4

Max nTPM: 163.0
Min nTPM: 110.8
Sample A Female 163.0
Sample B Female 110.8
Sample C Male 135.6
Sample D Male 138.0
Midbrain
nTPM: 131.5
Samples: 4

Max nTPM: 205.4
Min nTPM: 82.5
Sample A Female 205.4
Sample B Female 85.4
Sample C Male 152.6
Sample D Male 82.5
Periaqueductal gray
nTPM: 69.4
Samples: 3

Max nTPM: 82.2
Min nTPM: 58.7
Sample B Female 67.3
Sample C Male 82.2
Sample D Male 58.7
Superior colliculi
nTPM: 152.5
Samples: 4

Max nTPM: 226.9
Min nTPM: 108.3
Sample A Female 150.9
Sample B Female 124.0
Sample C Male 226.9
Sample D Male 108.3

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

34.8
Mouse sample Sample description nTPM
Midbrain
nTPM: 34.8
Samples: 4

Max nTPM: 38.1
Min nTPM: 32.7
Sample A Male 35.2
Sample B Male 33.2
Sample C Female 32.7
Sample D Female 38.1

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

0.6
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 0.6
77454961 Antisense, RP_070129_01_E04, Mouse strain C57BL/6J (56 days, male) 0.9
68302203 Antisense, RP_041130_02_D06, Mouse strain C57BL/6J (56 days, male) 0.8
77866850 Antisense, RP_070129_01_E04, Mouse strain C57BL/6J (56 days, male) 0.5
1181 Antisense, RP_Baylor_103301, Mouse strain C57BL/6J (56 days, male) 0.1

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