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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:320.7 nTPM
HPA Brain:80.7 nTPM
GTEx:320.7 nTPM
FANTOM5:347.2 Scaled Tags Per Million
Pig:127.8 nTPM
Mouse:465.6 nTPM
Allen mouse:17.0 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

80.7
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 63.0
2019 Male, age 18, unknown 78.3
1827 Male, age 72, unknown 70.4
2411 Female, age 72, unknown 68.8
1870 Female, age 42, unknown 68.1
1833 Male, age 53, unknown 62.1
2666 Male, age 74, left hemisphere 61.8
1830 Male, age 51, unknown 57.0
2219 Male, age 76, both hemispheres 57.0
2828 Female, age 72, unknown 55.1
2586 Male, age 75, left hemisphere 50.9
Dorsal raphe nucleus
nTPM: 68.3
1828 Male, age 53, unknown 83.9
2298 Female, age 72, unknown 71.7
2016 Female, age 72, unknown 64.0
2750 Male, age 76, both hemispheres 61.2
2047 Male, age 72, unknown 60.7
Inferior colliculus
nTPM: 70.9
1890 Male, age 53, unknown 77.5
2097 Female, age 72, unknown 72.5
2849 Male, age 72, unknown 71.6
1848 Female, age 42, unknown 62.0
Median raphe nucleus
nTPM: 62.1
2220 Male, age 76, midline 62.1
Periaquaductal grey, anterior
nTPM: 66.1
1947 Male, age 18, unknown 68.6
2502 Female, age 75, unknown 68.1
1795 Male, age 51, unknown 61.7
Periaquaductal grey, dorsal
nTPM: 60.1
2850 Male, age 76, both hemispheres 66.2
1840 Male, age 53, unknown 62.7
1831 Male, age 72, unknown 59.7
2464 Female, age 72, unknown 51.8
Periaquaductal grey, lateral
nTPM: 57.8
2053 Male, age 18, unknown 58.9
2272 Male, age 74, both hemispheres 58.1
2140 Male, age 76, both hemispheres 56.5
Pretectal area
nTPM: 72.4
1817 Female, age 42, unknown 95.7
1816 Male, age 51, unknown 91.3
2007 Male, age 72, unknown 89.5
1944 Female, age 72, unknown 85.5
1815 Male, age 53, unknown 80.2
2667 Female, age 75, unknown 69.9
2224 Female, age 72, unknown 61.2
2273 Male, age 74, both hemispheres 59.8
2825 Male, age 18, unknown 57.3
2407 Male, age 75, both hemispheres 54.2
2316 Male, age 76, right hemisphere 51.9
Red nucleus
nTPM: 72.0
1821 Female, age 72, unknown 93.2
2725 Female, age 75, unknown 87.5
2584 Male, age 75, left hemisphere 83.7
2503 Female, age 72, unknown 83.5
1865 Male, age 51, unknown 68.6
2588 Male, age 74, left hemisphere 68.2
1904 Male, age 53, unknown 66.1
2785 Male, age 18, unknown 65.3
2769 Male, age 72, unknown 63.3
2227 Male, age 72, unknown 63.1
2823 Male, age 76, right hemisphere 61.0
1954 Female, age 42, unknown 60.2
Substantia nigra
nTPM: 80.7
2409 Female, age 72, unknown 95.1
1889 Female, age 72, unknown 94.5
1916 Female, age 42, unknown 92.0
2665 Male, age 74, both hemispheres 83.5
2241 Male, age 72, unknown 82.7
2699 Male, age 18, unknown 82.4
1851 Male, age 51, unknown 82.0
1941 Male, age 53, unknown 73.3
2583 Male, age 75, right hemisphere 63.0
2590 Female, age 75, unknown 58.3
Superior colliculus
nTPM: 64.5
2587 Male, age 74, left hemisphere 82.2
2668 Female, age 75, unknown 69.9
1895 Male, age 76, right hemisphere 68.2
2087 Female, age 72, unknown 67.1
1913 Female, age 42, unknown 65.4
1839 Male, age 51, unknown 63.1
2261 Male, age 18, unknown 62.8
1995 Male, age 72, unknown 60.6
1796 Male, age 53, unknown 55.4
2664 Male, age 75, both hemispheres 50.7
Ventral tegmental area
nTPM: 66.4
2410 Female, age 72, unknown 77.9
1915 Female, age 42, unknown 70.7
2223 Female, age 72, unknown 67.6
2218 Male, age 76, both hemispheres 65.0
1942 Male, age 51, unknown 61.4
2021 Male, age 53, unknown 55.6

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

320.7
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 320.7
Samples: 139

Max nTPM: 776.1
Min nTPM: 155.3
Std nTPM: 92.8
Median nTPM: 305.0
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 776.1
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 687.2
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 568.1
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 550.9
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 537.8
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 498.9
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 452.2
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 448.6
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 441.2
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 437.7
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 437.5
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 437.3
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 432.7
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 430.7
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 430.1
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 430.0
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 423.5
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 414.9
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 413.9
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 411.9
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 408.6
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 399.1
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 394.1
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 387.6
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 386.3
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 381.9
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 381.0
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 378.7
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 376.2
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 375.4
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 373.8
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 372.1
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 371.1
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 369.5
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 367.5
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 365.7
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 365.4
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 364.8
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 363.5
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 360.4
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 356.4
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 354.4
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 351.8
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 351.8
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 347.3
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 347.0
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 346.7
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 338.9
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 338.7
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 336.8
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 335.6
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 334.8
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 334.3
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 333.9
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 331.3
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 329.2
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 326.3
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 325.8
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 324.9
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 324.1
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 322.0
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 319.7
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 316.1
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 311.9
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 310.5
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 309.1
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 308.2
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 308.1
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 305.8
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 305.0
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 304.2
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 300.8
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 300.0
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 299.1
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 297.2
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 295.6
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 294.6
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 294.4
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 293.2
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 293.1
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 290.7
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 290.6
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 289.5
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 289.3
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 288.0
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 287.1
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 286.5
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 284.9
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 281.0
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 280.9
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 279.8
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 279.7
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 274.3
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 273.3
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 272.3
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 271.8
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 270.0
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 269.2
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 268.6
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 268.0
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 267.9
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 267.6
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 264.7
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 262.3
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 262.1
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 258.6
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 258.5
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 257.7
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 253.9
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 253.5
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 252.9
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 252.3
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 251.9
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 250.1
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 249.0
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 247.2
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 243.7
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 241.8
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 241.0
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 240.5
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 238.7
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 237.9
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 232.1
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 230.1
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 225.0
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 223.6
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 216.6
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 216.0
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 215.9
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 204.8
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 200.1
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 190.4
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 188.1
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 186.9
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 178.1
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 173.6
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 166.0
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 158.0
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 155.3
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MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

347.2
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 347.2
FF:10158-103A5 76 years, female 347.2

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

127.8
Pig sample Sample description nTPM
Substantia nigra
nTPM: 106.2
Samples: 4

Max nTPM: 145.3
Min nTPM: 72.6
Sample A Female 145.3
Sample B Female 82.2
Sample C Male 124.7
Sample D Male 72.6
Midbrain
nTPM: 115.6
Samples: 4

Max nTPM: 143.9
Min nTPM: 88.5
Sample A Female 88.5
Sample B Female 107.7
Sample C Male 143.9
Sample D Male 122.1
Periaqueductal gray
nTPM: 95.2
Samples: 3

Max nTPM: 105.7
Min nTPM: 89.6
Sample B Female 89.6
Sample C Male 105.7
Sample D Male 90.4
Superior colliculi
nTPM: 127.9
Samples: 4

Max nTPM: 172.1
Min nTPM: 69.2
Sample A Female 142.0
Sample B Female 69.2
Sample C Male 172.1
Sample D Male 128.1

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

465.6
Mouse sample Sample description nTPM
Midbrain
nTPM: 465.6
Samples: 4

Max nTPM: 481.2
Min nTPM: 452.7
Sample A Male 481.2
Sample B Male 457.5
Sample C Female 470.8
Sample D Female 452.7

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

17.0
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 17.0
293241 Antisense, RP_040609_01_G11, Mouse strain C57BL/6J (56 days, male) 17.0
323595 Antisense, RP_040609_01_G11, Mouse strain C57BL/6J (56 days, male) 7.9

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