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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:90.9 nTPM
HPA Brain:216.4 nTPM
GTEx:90.9 nTPM
FANTOM5:96.2 Scaled Tags Per Million
Pig:132.6 nTPM
Mouse:75.5 nTPM
Allen mouse:6.5 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

216.4
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 197.5
2586 Male, age 75, left hemisphere 387.3
2828 Female, age 72, unknown 274.7
2666 Male, age 74, left hemisphere 249.6
1827 Male, age 72, unknown 183.8
1870 Female, age 42, unknown 168.1
1833 Male, age 53, unknown 154.3
2219 Male, age 76, both hemispheres 153.6
1830 Male, age 51, unknown 151.2
2411 Female, age 72, unknown 150.2
2019 Male, age 18, unknown 102.5
Dorsal raphe nucleus
nTPM: 199.1
1828 Male, age 53, unknown 236.2
2047 Male, age 72, unknown 234.5
2016 Female, age 72, unknown 209.6
2298 Female, age 72, unknown 164.6
2750 Male, age 76, both hemispheres 150.5
Inferior colliculus
nTPM: 153.8
2849 Male, age 72, unknown 170.2
1848 Female, age 42, unknown 167.6
1890 Male, age 53, unknown 154.4
2097 Female, age 72, unknown 123.1
Median raphe nucleus
nTPM: 163.0
2220 Male, age 76, midline 163.0
Periaquaductal grey, anterior
nTPM: 186.5
1795 Male, age 51, unknown 209.9
1947 Male, age 18, unknown 204.6
2502 Female, age 75, unknown 145.1
Periaquaductal grey, dorsal
nTPM: 167.3
1840 Male, age 53, unknown 186.4
1831 Male, age 72, unknown 170.1
2850 Male, age 76, both hemispheres 163.2
2464 Female, age 72, unknown 149.7
Periaquaductal grey, lateral
nTPM: 162.1
2053 Male, age 18, unknown 214.0
2140 Male, age 76, both hemispheres 155.9
2272 Male, age 74, both hemispheres 116.3
Pretectal area
nTPM: 161.5
2825 Male, age 18, unknown 217.7
2407 Male, age 75, both hemispheres 181.6
1815 Male, age 53, unknown 170.5
2667 Female, age 75, unknown 170.3
1944 Female, age 72, unknown 168.4
1817 Female, age 42, unknown 167.7
1816 Male, age 51, unknown 156.5
2224 Female, age 72, unknown 150.2
2007 Male, age 72, unknown 142.5
2316 Male, age 76, right hemisphere 138.3
2273 Male, age 74, both hemispheres 113.0
Red nucleus
nTPM: 182.5
2584 Male, age 75, left hemisphere 248.6
2503 Female, age 72, unknown 212.9
2588 Male, age 74, left hemisphere 212.7
2725 Female, age 75, unknown 196.6
2769 Male, age 72, unknown 190.6
2227 Male, age 72, unknown 182.8
1954 Female, age 42, unknown 181.2
1821 Female, age 72, unknown 167.4
2823 Male, age 76, right hemisphere 167.3
1865 Male, age 51, unknown 160.5
1904 Male, age 53, unknown 158.8
2785 Male, age 18, unknown 110.7
Substantia nigra
nTPM: 216.4
2699 Male, age 18, unknown 277.2
2583 Male, age 75, right hemisphere 264.3
1916 Female, age 42, unknown 245.2
2665 Male, age 74, both hemispheres 242.2
1851 Male, age 51, unknown 210.8
2409 Female, age 72, unknown 198.7
2590 Female, age 75, unknown 198.6
2241 Male, age 72, unknown 197.9
1889 Female, age 72, unknown 168.9
1941 Male, age 53, unknown 160.8
Superior colliculus
nTPM: 171.2
2664 Male, age 75, both hemispheres 284.7
1796 Male, age 53, unknown 198.6
2668 Female, age 75, unknown 192.8
2261 Male, age 18, unknown 179.3
1839 Male, age 51, unknown 173.1
2087 Female, age 72, unknown 159.4
2587 Male, age 74, left hemisphere 144.7
1995 Male, age 72, unknown 135.8
1913 Female, age 42, unknown 132.5
1895 Male, age 76, right hemisphere 110.8
Ventral tegmental area
nTPM: 186.7
1942 Male, age 51, unknown 218.5
2410 Female, age 72, unknown 201.7
1915 Female, age 42, unknown 190.1
2021 Male, age 53, unknown 189.7
2218 Male, age 76, both hemispheres 168.9
2223 Female, age 72, unknown 151.1

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

90.9
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 90.9
Samples: 139

Max nTPM: 232.6
Min nTPM: 19.0
Std nTPM: 39.7
Median nTPM: 83.8
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 232.6
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 207.1
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 187.2
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 185.1
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 156.1
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 155.5
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 154.5
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 154.4
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 150.8
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 148.3
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 148.3
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 147.5
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 144.7
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 141.5
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 141.3
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 139.6
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 139.5
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 139.0
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 135.1
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 135.0
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 134.6
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 132.4
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 132.0
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 131.9
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 131.8
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 129.9
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 128.4
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 128.2
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 127.5
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 125.4
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 125.1
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 125.1
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 123.3
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 122.7
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 118.9
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 118.1
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 117.7
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 117.3
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 115.2
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 114.4
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 111.7
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 111.5
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 111.4
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 109.5
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 106.2
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 104.2
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 103.8
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 103.3
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 103.1
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 102.7
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 102.5
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 101.7
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 99.4
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 99.2
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 99.1
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 98.3
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 97.9
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 96.4
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 94.7
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 94.2
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 94.0
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 92.9
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 91.0
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 90.1
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 90.0
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 88.6
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 86.7
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 85.8
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 83.9
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 83.8
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 83.3
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 82.6
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 82.6
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 82.1
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 81.7
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 80.9
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 80.6
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 79.6
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 79.2
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 76.7
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 76.0
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 75.1
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 75.1
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 74.8
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 74.5
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 73.4
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 73.0
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 72.4
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 70.4
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 70.3
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 69.9
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 68.7
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 68.6
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 68.6
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 67.9
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 67.7
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 67.5
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 65.8
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 65.2
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 64.2
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 63.8
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 63.3
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 62.9
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 62.9
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 62.0
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 61.5
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 61.4
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 61.3
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 60.9
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 60.8
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 60.3
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 59.2
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 58.2
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 55.2
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 53.7
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 52.5
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 50.8
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 50.1
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 48.7
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 48.5
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 47.8
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 47.5
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 45.8
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 44.2
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 41.9
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 41.5
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 40.6
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 38.3
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 38.0
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 36.9
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 36.5
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 35.3
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 34.6
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 31.3
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 28.2
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 25.2
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 23.7
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 20.0
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 19.0
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

96.2
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 96.2
FF:10158-103A5 76 years, female 96.2

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

132.6
Pig sample Sample description nTPM
Substantia nigra
nTPM: 132.6
Samples: 4

Max nTPM: 158.7
Min nTPM: 97.3
Sample A Female 134.1
Sample B Female 97.3
Sample C Male 158.7
Sample D Male 140.2
Midbrain
nTPM: 125.8
Samples: 4

Max nTPM: 208.3
Min nTPM: 83.2
Sample A Female 83.2
Sample B Female 104.3
Sample C Male 208.3
Sample D Male 107.2
Periaqueductal gray
nTPM: 95.4
Samples: 3

Max nTPM: 108.1
Min nTPM: 75.7
Sample B Female 108.1
Sample C Male 102.5
Sample D Male 75.7
Superior colliculi
nTPM: 118.6
Samples: 4

Max nTPM: 167.4
Min nTPM: 61.8
Sample A Female 114.8
Sample B Female 61.8
Sample C Male 167.4
Sample D Male 130.5

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

75.5
Mouse sample Sample description nTPM
Midbrain
nTPM: 75.5
Samples: 4

Max nTPM: 80.3
Min nTPM: 71.4
Sample A Male 80.3
Sample B Male 75.8
Sample C Female 71.4
Sample D Female 74.3

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

6.5
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 6.5
71358662 Antisense, RP_050725_03_F12, Mouse strain C57BL/6J (56 days, male) 6.8
68845287 Antisense, RP_050224_01_E03, Mouse strain C57BL/6J (56 days, male) 6.3

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