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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
PRIMARY MOUSE DATA
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Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:289.5 nTPM
HPA Brain:738.6 nTPM
GTEx:289.5 nTPM
FANTOM5:91.1 Scaled Tags Per Million
Pig:494.1 nTPM
Mouse:430.7 nTPM
Allen mouse:0.9 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

738.6
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 139.3
2219 Male, age 76, both hemispheres 660.7
2828 Female, age 72, unknown 131.7
2586 Male, age 75, left hemisphere 115.5
2666 Male, age 74, left hemisphere 101.7
1833 Male, age 53, unknown 77.7
2411 Female, age 72, unknown 74.3
1827 Male, age 72, unknown 66.2
1830 Male, age 51, unknown 60.2
1870 Female, age 42, unknown 56.1
2019 Male, age 18, unknown 49.2
Dorsal raphe nucleus
nTPM: 87.0
2016 Female, age 72, unknown 113.1
1828 Male, age 53, unknown 91.3
2047 Male, age 72, unknown 78.1
2750 Male, age 76, both hemispheres 76.8
2298 Female, age 72, unknown 75.6
Inferior colliculus
nTPM: 88.5
1890 Male, age 53, unknown 104.8
2097 Female, age 72, unknown 90.5
1848 Female, age 42, unknown 84.2
2849 Male, age 72, unknown 74.3
Median raphe nucleus
nTPM: 56.1
2220 Male, age 76, midline 56.1
Periaquaductal grey, anterior
nTPM: 62.7
2502 Female, age 75, unknown 88.3
1947 Male, age 18, unknown 53.8
1795 Male, age 51, unknown 46.1
Periaquaductal grey, dorsal
nTPM: 81.1
1840 Male, age 53, unknown 108.7
2464 Female, age 72, unknown 84.2
2850 Male, age 76, both hemispheres 72.9
1831 Male, age 72, unknown 58.6
Periaquaductal grey, lateral
nTPM: 54.3
2053 Male, age 18, unknown 61.3
2140 Male, age 76, both hemispheres 58.6
2272 Male, age 74, both hemispheres 43.0
Pretectal area
nTPM: 65.3
1815 Male, age 53, unknown 90.7
2667 Female, age 75, unknown 89.4
1944 Female, age 72, unknown 84.4
1817 Female, age 42, unknown 74.3
2316 Male, age 76, right hemisphere 65.2
2825 Male, age 18, unknown 63.8
1816 Male, age 51, unknown 59.3
2007 Male, age 72, unknown 56.2
2407 Male, age 75, both hemispheres 50.8
2273 Male, age 74, both hemispheres 42.4
2224 Female, age 72, unknown 41.7
Red nucleus
nTPM: 86.3
2503 Female, age 72, unknown 114.9
2725 Female, age 75, unknown 112.4
1821 Female, age 72, unknown 109.6
2823 Male, age 76, right hemisphere 108.4
2769 Male, age 72, unknown 87.7
1904 Male, age 53, unknown 84.8
2227 Male, age 72, unknown 84.8
2588 Male, age 74, left hemisphere 78.9
1954 Female, age 42, unknown 71.6
2584 Male, age 75, left hemisphere 70.3
1865 Male, age 51, unknown 69.0
2785 Male, age 18, unknown 42.7
Substantia nigra
nTPM: 738.6
2699 Male, age 18, unknown 2165.2
1916 Female, age 42, unknown 1633.0
2241 Male, age 72, unknown 939.8
1941 Male, age 53, unknown 928.2
1851 Male, age 51, unknown 830.7
2409 Female, age 72, unknown 425.3
1889 Female, age 72, unknown 161.1
2665 Male, age 74, both hemispheres 116.5
2590 Female, age 75, unknown 95.2
2583 Male, age 75, right hemisphere 91.2
Superior colliculus
nTPM: 77.7
2668 Female, age 75, unknown 121.3
2087 Female, age 72, unknown 94.2
1995 Male, age 72, unknown 90.0
1913 Female, age 42, unknown 76.7
1796 Male, age 53, unknown 74.4
2664 Male, age 75, both hemispheres 72.8
2587 Male, age 74, left hemisphere 72.5
1895 Male, age 76, right hemisphere 64.9
1839 Male, age 51, unknown 56.8
2261 Male, age 18, unknown 53.2
Ventral tegmental area
nTPM: 544.6
2218 Male, age 76, both hemispheres 1081.4
1915 Female, age 42, unknown 879.7
1942 Male, age 51, unknown 650.9
2410 Female, age 72, unknown 478.5
2223 Female, age 72, unknown 95.4
2021 Male, age 53, unknown 81.8

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

289.5
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 289.5
Samples: 139

Max nTPM: 1344.8
Min nTPM: 17.5
Std nTPM: 264.8
Median nTPM: 203.3
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 1344.8
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 1306.3
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 1089.1
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 1041.5
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 1023.9
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 978.0
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 944.1
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 911.2
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 904.5
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 853.4
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 779.6
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 756.5
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 737.0
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 698.8
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 599.5
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 588.1
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 586.7
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 538.2
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 537.5
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 536.9
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 514.7
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 486.5
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 477.0
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 448.6
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 438.6
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 437.0
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 434.3
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 431.9
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 420.8
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 420.6
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 410.7
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 390.3
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 375.8
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 364.8
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 362.6
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 351.4
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 344.9
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 321.8
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 320.7
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 305.0
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 299.8
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 295.0
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 293.0
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 291.7
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 285.3
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 282.4
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 261.3
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 260.5
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 255.3
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 249.5
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 242.6
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 239.9
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 238.7
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 235.7
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 233.5
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 232.8
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 232.1
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 224.5
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 217.7
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 216.4
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 216.1
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 215.4
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 215.1
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 214.7
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 207.3
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 206.8
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 206.5
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 205.0
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 203.5
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 203.3
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 198.9
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 197.7
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 195.2
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 195.0
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 186.9
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 185.7
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 184.8
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 183.5
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 183.3
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 182.6
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 182.1
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 177.5
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 173.9
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 168.2
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 167.5
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 167.4
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 166.1
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 165.5
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 164.4
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 163.8
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 156.6
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 154.8
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 153.5
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 153.0
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 145.3
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 145.0
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 137.9
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 136.7
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 129.7
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 123.6
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 121.7
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 120.5
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 119.5
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 119.3
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 116.4
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 115.6
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 112.8
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 111.2
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 109.7
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 107.8
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 107.4
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 106.4
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 103.7
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 101.9
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 101.4
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 94.6
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 92.9
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 92.3
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 91.3
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 86.4
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 78.5
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 77.9
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 72.8
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 72.2
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 69.7
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 68.8
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 66.0
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 65.5
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 64.8
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 60.1
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 57.2
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 55.3
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 54.8
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 49.0
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 47.9
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 38.0
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 37.3
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 27.8
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 17.5
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

91.1
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 91.1
FF:10158-103A5 76 years, female 91.1

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

494.1
Pig sample Sample description nTPM
Substantia nigra
nTPM: 494.1
Samples: 4

Max nTPM: 852.9
Min nTPM: 31.6
Sample A Female 638.2
Sample B Female 453.7
Sample C Male 852.9
Sample D Male 31.6
Midbrain
nTPM: 76.8
Samples: 4

Max nTPM: 208.0
Min nTPM: 25.5
Sample A Female 46.3
Sample B Female 208.0
Sample C Male 25.5
Sample D Male 27.5
Periaqueductal gray
nTPM: 81.1
Samples: 3

Max nTPM: 100.5
Min nTPM: 55.3
Sample B Female 87.4
Sample C Male 55.3
Sample D Male 100.5
Superior colliculi
nTPM: 35.5
Samples: 4

Max nTPM: 69.1
Min nTPM: 15.5
Sample A Female 28.7
Sample B Female 69.1
Sample C Male 15.5
Sample D Male 28.5

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

430.7
Mouse sample Sample description nTPM
Midbrain
nTPM: 430.7
Samples: 4

Max nTPM: 446.7
Min nTPM: 420.3
Sample A Male 422.7
Sample B Male 420.3
Sample C Female 446.7
Sample D Female 433.1

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

0.9
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 0.9
72103809 Antisense, RP_051017_03_D07, Mouse strain C57BL/6J (56 days, male) 1.0
69013627 Antisense, RP_050309_02_F10, Mouse strain C57BL/6J (56 days, male) 0.8

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