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Similar staining to SCG2 but somehow more restricted in terms of anatomical distribution.
Moderate-strong diffuse-synaptic immunoreactivity is noticed in some distinct brain areas:
Strong diffuse-synaptic immunostaining is noticed in the lateral septum, ventral pallidum, shall of the nucleus accumbens, the preoptic area, some nuclei of BNST, some nuclei of the tuberal hypothalamus (paraventricular-, dorsomedial-, periventricular and arcuate nuclei), thalamic paraventricular nucleus, hippocampus mossy fibers, central amygdala, periaqueductal gray matter, some nuclei of the medulla, like parabrachial nucleus, dorsal raphe, locus coeruleus.
Moderate-weak synaptic immunoreactivity is noticed in all layers of the olfactory bulb, in midline thalamic nuclei, substantia nigra, and some medullar nuclei.
The median eminence and area postrema exhibits strong immunoreactivity.
Positive cells and structuresi
Manually selected location of the protein positivity, observed by immunofluorescence staining in mouse brain.
Synapse in neurons. Circumventricular organs of ependymal cells.
The Human Protein Atlas project is funded
