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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
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Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:562.1 nTPM
HPA Brain:306.9 nTPM
GTEx:562.1 nTPM
FANTOM5:226.8 Scaled Tags Per Million
Pig:729.8 nTPM
Mouse:488.7 nTPM
Allen mouse:5.3 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

306.9
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 253.6
2019 Male, age 18, unknown 333.9
2586 Male, age 75, left hemisphere 283.6
2411 Female, age 72, unknown 271.9
1827 Male, age 72, unknown 271.0
2828 Female, age 72, unknown 261.8
2666 Male, age 74, left hemisphere 235.1
2219 Male, age 76, both hemispheres 233.5
1870 Female, age 42, unknown 231.7
1833 Male, age 53, unknown 217.8
1830 Male, age 51, unknown 195.7
Dorsal raphe nucleus
nTPM: 281.7
2298 Female, age 72, unknown 371.2
1828 Male, age 53, unknown 301.8
2047 Male, age 72, unknown 270.5
2750 Male, age 76, both hemispheres 238.6
2016 Female, age 72, unknown 226.5
Inferior colliculus
nTPM: 275.0
2097 Female, age 72, unknown 353.6
1890 Male, age 53, unknown 309.9
1848 Female, age 42, unknown 237.5
2849 Male, age 72, unknown 199.2
Median raphe nucleus
nTPM: 218.4
2220 Male, age 76, midline 218.4
Periaquaductal grey, anterior
nTPM: 268.3
2502 Female, age 75, unknown 280.7
1947 Male, age 18, unknown 262.4
1795 Male, age 51, unknown 261.8
Periaquaductal grey, dorsal
nTPM: 224.8
1831 Male, age 72, unknown 230.2
1840 Male, age 53, unknown 228.1
2850 Male, age 76, both hemispheres 224.7
2464 Female, age 72, unknown 216.1
Periaquaductal grey, lateral
nTPM: 221.7
2272 Male, age 74, both hemispheres 228.3
2053 Male, age 18, unknown 221.6
2140 Male, age 76, both hemispheres 215.2
Pretectal area
nTPM: 303.7
2007 Male, age 72, unknown 431.5
1816 Male, age 51, unknown 410.8
1817 Female, age 42, unknown 389.1
1815 Male, age 53, unknown 327.1
2667 Female, age 75, unknown 320.4
1944 Female, age 72, unknown 318.1
2273 Male, age 74, both hemispheres 264.5
2224 Female, age 72, unknown 248.7
2316 Male, age 76, right hemisphere 245.9
2825 Male, age 18, unknown 219.9
2407 Male, age 75, both hemispheres 164.4
Red nucleus
nTPM: 290.9
1821 Female, age 72, unknown 415.9
2785 Male, age 18, unknown 312.2
2503 Female, age 72, unknown 310.7
2588 Male, age 74, left hemisphere 296.9
2725 Female, age 75, unknown 286.1
2823 Male, age 76, right hemisphere 284.9
1904 Male, age 53, unknown 282.7
2769 Male, age 72, unknown 281.5
2227 Male, age 72, unknown 280.7
1954 Female, age 42, unknown 265.3
1865 Male, age 51, unknown 264.9
2584 Male, age 75, left hemisphere 208.6
Substantia nigra
nTPM: 306.9
1916 Female, age 42, unknown 411.1
1851 Male, age 51, unknown 383.6
1889 Female, age 72, unknown 343.4
2665 Male, age 74, both hemispheres 338.4
1941 Male, age 53, unknown 294.8
2241 Male, age 72, unknown 268.6
2699 Male, age 18, unknown 267.5
2590 Female, age 75, unknown 264.3
2409 Female, age 72, unknown 259.6
2583 Male, age 75, right hemisphere 237.5
Superior colliculus
nTPM: 258.1
2087 Female, age 72, unknown 292.9
1796 Male, age 53, unknown 284.6
2261 Male, age 18, unknown 273.2
2587 Male, age 74, left hemisphere 271.8
1895 Male, age 76, right hemisphere 261.7
2668 Female, age 75, unknown 257.6
1995 Male, age 72, unknown 255.8
1913 Female, age 42, unknown 241.2
1839 Male, age 51, unknown 227.1
2664 Male, age 75, both hemispheres 214.8
Ventral tegmental area
nTPM: 279.4
1915 Female, age 42, unknown 353.7
2410 Female, age 72, unknown 319.7
2223 Female, age 72, unknown 274.7
2218 Male, age 76, both hemispheres 269.5
1942 Male, age 51, unknown 249.1
2021 Male, age 53, unknown 209.5

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

562.1
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 562.1
Samples: 139

Max nTPM: 1115.8
Min nTPM: 241.5
Std nTPM: 150.1
Median nTPM: 551.3
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 1115.8
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 912.5
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 901.5
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 891.9
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 860.1
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 858.8
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 847.6
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 835.5
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 809.4
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 808.5
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 808.4
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 802.0
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 797.8
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 774.0
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 760.3
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 756.5
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 746.0
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 736.2
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 732.8
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 727.7
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 717.4
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 709.7
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 707.2
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 688.9
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 684.7
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 684.3
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 679.4
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 672.2
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 667.8
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 664.6
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 662.4
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 657.9
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 648.4
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 645.7
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 645.0
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 643.0
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 638.8
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 630.6
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 629.3
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 627.9
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 626.9
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 625.4
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 622.2
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 621.1
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 619.6
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 618.6
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 613.4
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 611.6
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 611.3
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 607.3
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 606.0
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 605.9
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 604.9
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 601.3
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 597.5
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 597.0
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 582.0
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 575.6
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 574.5
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 568.1
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 565.8
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 564.2
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 563.0
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 562.1
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 559.9
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 559.8
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 558.8
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 556.0
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 554.7
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 551.3
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 548.8
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 547.9
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 547.1
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 544.2
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 543.3
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 542.7
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 542.4
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 528.7
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 526.5
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 523.2
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 522.8
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 520.0
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 509.0
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 508.0
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 504.4
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 503.2
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 501.7
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 499.9
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 499.9
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 497.3
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 497.3
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 496.2
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 494.7
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 493.0
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 492.9
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 491.8
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 490.5
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 485.5
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 475.8
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 474.5
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 464.4
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 463.5
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 459.6
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 456.6
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 456.3
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 454.8
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 454.6
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 448.7
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 448.5
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 445.6
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 444.7
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 441.2
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 437.7
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 429.9
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 414.6
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 412.5
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 408.5
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 407.1
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 403.3
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 401.9
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 398.7
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 398.6
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 392.1
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 387.5
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 373.5
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 372.6
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 370.5
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 368.0
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 359.2
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 359.0
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 344.1
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 337.7
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 333.1
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 332.3
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 324.3
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 300.8
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 285.5
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 274.3
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 241.5
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MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

226.8
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 226.8
FF:10158-103A5 76 years, female 226.8

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

729.8
Pig sample Sample description nTPM
Substantia nigra
nTPM: 588.4
Samples: 4

Max nTPM: 888.0
Min nTPM: 404.0
Sample A Female 888.0
Sample B Female 491.3
Sample C Male 570.1
Sample D Male 404.0
Midbrain
nTPM: 648.7
Samples: 4

Max nTPM: 758.7
Min nTPM: 556.2
Sample A Female 693.9
Sample B Female 556.2
Sample C Male 758.7
Sample D Male 586.0
Periaqueductal gray
nTPM: 476.0
Samples: 3

Max nTPM: 526.0
Min nTPM: 418.5
Sample B Female 483.5
Sample C Male 526.0
Sample D Male 418.5
Superior colliculi
nTPM: 729.8
Samples: 4

Max nTPM: 905.1
Min nTPM: 579.6
Sample A Female 905.1
Sample B Female 638.6
Sample C Male 795.7
Sample D Male 579.6

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

488.7
Mouse sample Sample description nTPM
Midbrain
nTPM: 488.7
Samples: 4

Max nTPM: 535.4
Min nTPM: 460.8
Sample A Male 535.4
Sample B Male 486.9
Sample C Female 460.8
Sample D Female 471.7

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

5.3
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 5.3
69568986 Antisense, RP_050426_03_C02, Mouse strain C57BL/6J (56 days, male) 5.3

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