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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:38.6 nTPM
HPA Brain:139.6 nTPM
GTEx:38.6 nTPM
FANTOM5:87.3 Scaled Tags Per Million
Mouse:62.9 nTPM
Allen mouse:2.0 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

139.6
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 104.5
1830 Male, age 51, unknown 130.4
2586 Male, age 75, left hemisphere 130.2
1833 Male, age 53, unknown 124.2
2411 Female, age 72, unknown 118.3
1870 Female, age 42, unknown 113.1
2019 Male, age 18, unknown 104.6
2828 Female, age 72, unknown 102.6
1827 Male, age 72, unknown 77.0
2666 Male, age 74, left hemisphere 76.5
2219 Male, age 76, both hemispheres 67.6
Dorsal raphe nucleus
nTPM: 76.5
2750 Male, age 76, both hemispheres 129.7
2016 Female, age 72, unknown 92.2
1828 Male, age 53, unknown 71.2
2047 Male, age 72, unknown 45.9
2298 Female, age 72, unknown 43.6
Inferior colliculus
nTPM: 64.8
2849 Male, age 72, unknown 79.4
1848 Female, age 42, unknown 67.4
1890 Male, age 53, unknown 65.9
2097 Female, age 72, unknown 46.6
Median raphe nucleus
nTPM: 41.5
2220 Male, age 76, midline 41.5
Periaquaductal grey, anterior
nTPM: 67.8
1947 Male, age 18, unknown 73.8
2502 Female, age 75, unknown 73.7
1795 Male, age 51, unknown 56.0
Periaquaductal grey, dorsal
nTPM: 49.6
2464 Female, age 72, unknown 76.8
1831 Male, age 72, unknown 49.1
1840 Male, age 53, unknown 38.4
2850 Male, age 76, both hemispheres 34.0
Periaquaductal grey, lateral
nTPM: 58.7
2272 Male, age 74, both hemispheres 80.1
2053 Male, age 18, unknown 58.6
2140 Male, age 76, both hemispheres 37.4
Pretectal area
nTPM: 68.0
2316 Male, age 76, right hemisphere 107.4
2407 Male, age 75, both hemispheres 97.3
1815 Male, age 53, unknown 90.8
2825 Male, age 18, unknown 76.4
2007 Male, age 72, unknown 69.1
1817 Female, age 42, unknown 67.9
2224 Female, age 72, unknown 58.0
2273 Male, age 74, both hemispheres 58.0
2667 Female, age 75, unknown 50.0
1816 Male, age 51, unknown 37.2
1944 Female, age 72, unknown 35.7
Red nucleus
nTPM: 139.6
1904 Male, age 53, unknown 157.2
2769 Male, age 72, unknown 156.8
2785 Male, age 18, unknown 156.5
2823 Male, age 76, right hemisphere 151.4
1865 Male, age 51, unknown 149.9
2227 Male, age 72, unknown 147.0
2503 Female, age 72, unknown 143.8
2588 Male, age 74, left hemisphere 132.6
1954 Female, age 42, unknown 125.1
1821 Female, age 72, unknown 123.5
2584 Male, age 75, left hemisphere 116.9
2725 Female, age 75, unknown 114.5
Substantia nigra
nTPM: 76.0
2583 Male, age 75, right hemisphere 137.8
2590 Female, age 75, unknown 105.4
1851 Male, age 51, unknown 86.9
2699 Male, age 18, unknown 79.7
2409 Female, age 72, unknown 78.1
1889 Female, age 72, unknown 69.9
1916 Female, age 42, unknown 55.0
1941 Male, age 53, unknown 49.8
2241 Male, age 72, unknown 48.8
2665 Male, age 74, both hemispheres 48.6
Superior colliculus
nTPM: 90.9
1995 Male, age 72, unknown 149.9
1913 Female, age 42, unknown 128.0
1895 Male, age 76, right hemisphere 117.0
1839 Male, age 51, unknown 101.8
2587 Male, age 74, left hemisphere 87.1
2668 Female, age 75, unknown 81.9
2664 Male, age 75, both hemispheres 79.7
1796 Male, age 53, unknown 75.7
2261 Male, age 18, unknown 48.1
2087 Female, age 72, unknown 39.8
Ventral tegmental area
nTPM: 78.5
2410 Female, age 72, unknown 97.3
2223 Female, age 72, unknown 88.1
1942 Male, age 51, unknown 79.5
2021 Male, age 53, unknown 74.6
1915 Female, age 42, unknown 70.2
2218 Male, age 76, both hemispheres 61.3

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

38.6
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 38.6
Samples: 139

Max nTPM: 150.6
Min nTPM: 8.8
Std nTPM: 25.6
Median nTPM: 30.8
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 150.6
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 146.6
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 119.8
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 104.6
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 102.6
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 95.2
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 92.1
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 91.2
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 88.9
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 87.4
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 87.2
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 80.2
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 78.6
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 77.7
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 72.4
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 72.2
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 66.7
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 63.1
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 62.4
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 61.4
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 60.8
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 60.3
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 58.3
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 57.3
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 53.5
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 52.9
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 52.7
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 51.9
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 51.9
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 51.0
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 49.8
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 49.0
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 48.1
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 47.7
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 47.6
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 47.4
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 47.3
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 47.2
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 45.2
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 43.1
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 42.4
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 41.6
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 41.2
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 39.9
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 39.2
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 38.2
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 37.6
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 37.4
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 36.8
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 36.7
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 36.4
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 36.0
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 36.0
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 35.7
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 35.6
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 34.7
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 33.8
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 33.4
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 33.0
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 32.9
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 32.6
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 32.2
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 32.0
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 31.9
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 31.8
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 31.4
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 31.2
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 31.0
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 30.8
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 30.8
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 30.5
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 30.3
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 29.8
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 29.8
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 29.4
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 29.4
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 29.3
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 29.2
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 29.0
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 28.9
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 28.3
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 28.3
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 27.7
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 27.5
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 27.5
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 27.5
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 27.1
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 27.1
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 26.7
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 26.0
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 25.8
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 25.5
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 25.3
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 24.8
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 24.2
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 23.9
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 23.8
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 23.4
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 22.5
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 22.4
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 22.3
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 22.2
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 22.2
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 21.9
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 21.8
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 21.7
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 21.4
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 21.3
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 21.2
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 21.1
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 20.5
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 20.2
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 19.9
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 19.8
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 19.6
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 19.6
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 19.3
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 19.2
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 18.6
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 18.5
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 17.9
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 17.2
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 17.0
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 15.9
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 15.8
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 15.3
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 15.1
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 15.1
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 14.8
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 14.2
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 14.2
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 13.6
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 12.6
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 12.6
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 12.5
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 12.4
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 11.5
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 9.6
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 8.8
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

87.3
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 87.3
FF:10158-103A5 76 years, female 87.3

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

62.9
Mouse sample Sample description nTPM
Midbrain
nTPM: 62.9
Samples: 4

Max nTPM: 69.8
Min nTPM: 58.8
Sample A Male 69.8
Sample B Male 58.8
Sample C Female 60.0
Sample D Female 63.0

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

2.0
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 2.0
69447782 Antisense, RP_050419_02_A12, Mouse strain C57BL/6J (56 days, male) 2.0

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