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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:1000.2 nTPM
HPA Brain:334.5 nTPM
GTEx:1000.2 nTPM
FANTOM5:36.5 Scaled Tags Per Million
Pig:140.0 nTPM
Mouse:838.4 nTPM
Allen mouse:0.5 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

334.5
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 290.6
2666 Male, age 74, left hemisphere 353.8
1870 Female, age 42, unknown 339.3
2586 Male, age 75, left hemisphere 317.8
2828 Female, age 72, unknown 291.0
1833 Male, age 53, unknown 278.6
2411 Female, age 72, unknown 273.2
2019 Male, age 18, unknown 271.9
1827 Male, age 72, unknown 270.7
1830 Male, age 51, unknown 270.4
2219 Male, age 76, both hemispheres 239.2
Dorsal raphe nucleus
nTPM: 263.2
2016 Female, age 72, unknown 278.1
2750 Male, age 76, both hemispheres 273.8
1828 Male, age 53, unknown 269.5
2298 Female, age 72, unknown 268.6
2047 Male, age 72, unknown 226.0
Inferior colliculus
nTPM: 286.0
1890 Male, age 53, unknown 318.0
2849 Male, age 72, unknown 312.1
2097 Female, age 72, unknown 257.5
1848 Female, age 42, unknown 256.6
Median raphe nucleus
nTPM: 274.6
2220 Male, age 76, midline 274.6
Periaquaductal grey, anterior
nTPM: 270.7
2502 Female, age 75, unknown 321.8
1795 Male, age 51, unknown 257.7
1947 Male, age 18, unknown 232.5
Periaquaductal grey, dorsal
nTPM: 287.5
2850 Male, age 76, both hemispheres 334.4
1840 Male, age 53, unknown 291.4
1831 Male, age 72, unknown 267.0
2464 Female, age 72, unknown 257.0
Periaquaductal grey, lateral
nTPM: 258.4
2053 Male, age 18, unknown 300.3
2140 Male, age 76, both hemispheres 261.1
2272 Male, age 74, both hemispheres 213.8
Pretectal area
nTPM: 272.3
1815 Male, age 53, unknown 318.4
1817 Female, age 42, unknown 303.0
1816 Male, age 51, unknown 291.2
2825 Male, age 18, unknown 284.7
2407 Male, age 75, both hemispheres 270.1
2224 Female, age 72, unknown 269.9
1944 Female, age 72, unknown 267.9
2316 Male, age 76, right hemisphere 266.3
2007 Male, age 72, unknown 261.6
2667 Female, age 75, unknown 241.8
2273 Male, age 74, both hemispheres 219.9
Red nucleus
nTPM: 314.9
2503 Female, age 72, unknown 372.3
1865 Male, age 51, unknown 364.2
1904 Male, age 53, unknown 342.0
2584 Male, age 75, left hemisphere 340.4
1821 Female, age 72, unknown 333.9
2725 Female, age 75, unknown 326.8
2769 Male, age 72, unknown 302.4
2785 Male, age 18, unknown 296.4
2227 Male, age 72, unknown 285.0
2588 Male, age 74, left hemisphere 282.2
2823 Male, age 76, right hemisphere 267.8
1954 Female, age 42, unknown 264.9
Substantia nigra
nTPM: 334.5
2409 Female, age 72, unknown 441.1
2699 Male, age 18, unknown 402.7
2241 Male, age 72, unknown 385.0
2665 Male, age 74, both hemispheres 373.9
1851 Male, age 51, unknown 367.0
1889 Female, age 72, unknown 298.0
2590 Female, age 75, unknown 293.5
1916 Female, age 42, unknown 292.3
2583 Male, age 75, right hemisphere 266.7
1941 Male, age 53, unknown 224.6
Superior colliculus
nTPM: 293.1
1913 Female, age 42, unknown 383.8
2587 Male, age 74, left hemisphere 368.6
1995 Male, age 72, unknown 349.9
2668 Female, age 75, unknown 288.3
1796 Male, age 53, unknown 284.9
2664 Male, age 75, both hemispheres 277.0
1839 Male, age 51, unknown 256.1
2261 Male, age 18, unknown 246.5
2087 Female, age 72, unknown 238.6
1895 Male, age 76, right hemisphere 236.7
Ventral tegmental area
nTPM: 304.9
1915 Female, age 42, unknown 346.1
2223 Female, age 72, unknown 334.2
2021 Male, age 53, unknown 309.7
2410 Female, age 72, unknown 304.7
1942 Male, age 51, unknown 271.4
2218 Male, age 76, both hemispheres 263.2

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

1000.2
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 1000.2
Samples: 139

Max nTPM: 3434.5
Min nTPM: 298.9
Std nTPM: 452.7
Median nTPM: 884.5
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 3434.5
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 2505.3
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 2443.1
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 2375.6
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 2237.2
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 2220.0
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 1839.2
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 1651.9
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 1642.5
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 1635.6
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 1620.5
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 1589.8
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 1581.0
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 1565.2
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 1539.9
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 1527.7
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 1460.3
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 1411.2
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 1407.4
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 1371.0
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 1352.7
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 1304.5
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 1274.5
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 1249.0
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 1248.3
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 1240.7
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 1230.1
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 1227.2
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 1196.5
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 1187.2
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 1186.6
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 1170.8
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 1155.6
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 1144.6
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 1143.8
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 1141.7
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 1135.6
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 1124.1
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 1118.5
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 1113.8
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 1111.0
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 1091.4
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 1089.0
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 1088.7
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 1086.3
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 1083.9
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 1083.7
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 1060.8
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 1057.3
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 1056.4
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 1053.6
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 1052.5
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 1050.0
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 1047.6
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 1040.6
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 1039.6
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 1038.2
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 1030.1
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 1024.8
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 1010.0
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 1008.9
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 979.4
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 957.5
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 943.7
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 920.3
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 914.8
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 907.8
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 893.6
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 884.5
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 884.5
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 880.9
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 879.0
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 873.7
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 866.8
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 857.4
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 852.4
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 833.8
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 829.8
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 822.4
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 812.6
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 812.3
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 811.3
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 805.1
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 803.5
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 800.8
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 798.3
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 788.1
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 784.4
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 783.9
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 780.8
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 778.4
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 767.8
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 758.0
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 746.5
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 745.9
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 745.9
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 732.9
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 732.7
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 728.6
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 723.8
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 723.5
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 721.1
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 720.8
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 713.2
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 703.2
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 701.8
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 695.9
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 690.8
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 689.8
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 684.9
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 666.0
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 662.9
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 660.9
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 648.1
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 644.2
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 640.8
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 634.2
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 622.4
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 619.9
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 618.4
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 613.2
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 612.7
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 607.0
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 591.7
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 579.0
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 577.7
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 573.5
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 565.4
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 564.4
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 558.6
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 555.5
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 549.3
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 546.2
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 541.9
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 507.2
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 449.0
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 440.3
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 405.9
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 298.9
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

36.5
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 36.5
FF:10158-103A5 76 years, female 36.5

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

140.0
Pig sample Sample description nTPM
Substantia nigra
nTPM: 140.0
Samples: 4

Max nTPM: 182.0
Min nTPM: 110.2
Sample A Female 182.0
Sample B Female 147.6
Sample C Male 110.2
Sample D Male 120.3
Midbrain
nTPM: 138.7
Samples: 4

Max nTPM: 218.6
Min nTPM: 85.9
Sample A Female 218.6
Sample B Female 148.8
Sample C Male 101.6
Sample D Male 85.9
Periaqueductal gray
nTPM: 110.7
Samples: 3

Max nTPM: 121.2
Min nTPM: 101.8
Sample B Female 121.2
Sample C Male 109.2
Sample D Male 101.8
Superior colliculi
nTPM: 132.2
Samples: 4

Max nTPM: 159.1
Min nTPM: 118.8
Sample A Female 159.1
Sample B Female 128.3
Sample C Male 122.6
Sample D Male 118.8

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

838.4
Mouse sample Sample description nTPM
Midbrain
nTPM: 838.4
Samples: 4

Max nTPM: 918.7
Min nTPM: 752.9
Sample A Male 918.7
Sample B Male 821.0
Sample C Female 752.9
Sample D Female 861.0

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

0.5
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 0.5
71763583 Antisense, RP_050921_02_C07, Mouse strain C57BL/6J (56 days, male) 0.5

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