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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:469.1 nTPM
HPA Brain:1437.7 nTPM
GTEx:469.1 nTPM
FANTOM5:1362.1 Scaled Tags Per Million
Pig:867.6 nTPM
Mouse:1056.8 nTPM
Allen mouse:18.1 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

1437.7
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 1277.4
2666 Male, age 74, left hemisphere 1759.6
1827 Male, age 72, unknown 1407.7
2019 Male, age 18, unknown 1394.6
2586 Male, age 75, left hemisphere 1327.8
2828 Female, age 72, unknown 1277.3
2411 Female, age 72, unknown 1260.6
1870 Female, age 42, unknown 1252.8
1833 Male, age 53, unknown 1122.6
1830 Male, age 51, unknown 1107.2
2219 Male, age 76, both hemispheres 863.6
Dorsal raphe nucleus
nTPM: 1425.7
2298 Female, age 72, unknown 1852.3
2016 Female, age 72, unknown 1445.0
1828 Male, age 53, unknown 1388.5
2047 Male, age 72, unknown 1346.8
2750 Male, age 76, both hemispheres 1095.9
Inferior colliculus
nTPM: 1221.6
2097 Female, age 72, unknown 1433.1
1848 Female, age 42, unknown 1192.5
1890 Male, age 53, unknown 1158.3
2849 Male, age 72, unknown 1102.5
Median raphe nucleus
nTPM: 1148.9
2220 Male, age 76, midline 1148.9
Periaquaductal grey, anterior
nTPM: 1376.1
1947 Male, age 18, unknown 1526.9
1795 Male, age 51, unknown 1360.5
2502 Female, age 75, unknown 1240.7
Periaquaductal grey, dorsal
nTPM: 1288.2
1840 Male, age 53, unknown 1427.7
2850 Male, age 76, both hemispheres 1350.2
1831 Male, age 72, unknown 1289.1
2464 Female, age 72, unknown 1085.9
Periaquaductal grey, lateral
nTPM: 1407.1
2272 Male, age 74, both hemispheres 1632.1
2140 Male, age 76, both hemispheres 1354.8
2053 Male, age 18, unknown 1234.4
Pretectal area
nTPM: 1437.7
2273 Male, age 74, both hemispheres 1928.3
1817 Female, age 42, unknown 1566.7
1944 Female, age 72, unknown 1550.2
1816 Male, age 51, unknown 1503.1
2007 Male, age 72, unknown 1493.5
2667 Female, age 75, unknown 1486.9
2224 Female, age 72, unknown 1472.1
1815 Male, age 53, unknown 1408.7
2825 Male, age 18, unknown 1217.4
2407 Male, age 75, both hemispheres 1109.2
2316 Male, age 76, right hemisphere 1078.9
Red nucleus
nTPM: 1184.1
1821 Female, age 72, unknown 1441.6
2725 Female, age 75, unknown 1421.2
2785 Male, age 18, unknown 1272.6
2503 Female, age 72, unknown 1253.0
1954 Female, age 42, unknown 1204.7
1865 Male, age 51, unknown 1178.8
1904 Male, age 53, unknown 1155.8
2584 Male, age 75, left hemisphere 1124.2
2769 Male, age 72, unknown 1119.3
2227 Male, age 72, unknown 1085.7
2823 Male, age 76, right hemisphere 1035.5
2588 Male, age 74, left hemisphere 916.4
Substantia nigra
nTPM: 1411.3
1916 Female, age 42, unknown 1910.6
1851 Male, age 51, unknown 1658.6
1889 Female, age 72, unknown 1435.5
1941 Male, age 53, unknown 1434.6
2241 Male, age 72, unknown 1393.8
2583 Male, age 75, right hemisphere 1362.8
2409 Female, age 72, unknown 1293.0
2699 Male, age 18, unknown 1292.1
2590 Female, age 75, unknown 1286.5
2665 Male, age 74, both hemispheres 1045.3
Superior colliculus
nTPM: 1274.5
1796 Male, age 53, unknown 1446.7
1995 Male, age 72, unknown 1403.3
2087 Female, age 72, unknown 1374.9
2261 Male, age 18, unknown 1353.3
2587 Male, age 74, left hemisphere 1297.5
1913 Female, age 42, unknown 1264.0
2668 Female, age 75, unknown 1200.8
1839 Male, age 51, unknown 1173.2
2664 Male, age 75, both hemispheres 1139.7
1895 Male, age 76, right hemisphere 1091.6
Ventral tegmental area
nTPM: 1366.3
1915 Female, age 42, unknown 1701.0
2410 Female, age 72, unknown 1470.7
1942 Male, age 51, unknown 1330.5
2021 Male, age 53, unknown 1266.8
2223 Female, age 72, unknown 1227.6
2218 Male, age 76, both hemispheres 1201.1

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

469.1
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 469.1
Samples: 139

Max nTPM: 882.5
Min nTPM: 79.2
Std nTPM: 179.1
Median nTPM: 457.2
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 882.5
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 873.0
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 872.6
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 863.7
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 860.2
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 850.4
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 826.6
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 808.5
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 797.1
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 782.8
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 757.5
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 753.0
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 746.9
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 737.6
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 706.9
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 706.8
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 705.5
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 683.7
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 680.9
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 665.0
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 657.9
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 650.4
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 648.3
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 640.1
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 634.6
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 624.7
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 623.3
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 622.2
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 619.7
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 612.6
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 598.7
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 594.9
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 593.4
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 576.6
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 573.8
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 572.6
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 571.4
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 569.4
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 568.1
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 565.7
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 564.6
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 562.0
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 554.5
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 549.1
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 544.5
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 543.2
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 539.8
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 533.7
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 517.2
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 515.4
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 510.7
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 508.5
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 507.7
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 504.5
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 502.4
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 492.5
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 488.0
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 487.9
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 486.1
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 484.5
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 475.7
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 472.3
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 471.8
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 466.6
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 464.9
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 464.2
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 463.3
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 462.8
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 461.4
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 457.2
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 457.0
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 450.8
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 449.3
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 448.9
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 446.9
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 443.5
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 442.8
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 440.6
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 436.2
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 428.2
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 424.8
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 423.2
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 419.8
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 416.6
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 416.5
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 412.4
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 397.7
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 396.0
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 391.2
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 391.0
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 391.0
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 388.4
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 387.2
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 379.8
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 379.6
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 370.5
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 369.3
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 368.6
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 362.5
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 361.5
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 354.7
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 349.2
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 348.5
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 342.4
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 337.9
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 336.6
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 334.6
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 327.5
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 327.2
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 324.0
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 321.9
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 310.2
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 297.1
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 296.2
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 293.9
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 276.6
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 273.9
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 266.3
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 265.3
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 262.1
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 261.0
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 253.5
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 246.9
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 244.7
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 243.6
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 240.7
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 240.2
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 227.8
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 213.7
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 211.9
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 211.2
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 210.4
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 209.9
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 198.5
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 180.5
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 178.5
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 164.9
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 111.8
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 79.2
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MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

1362.1
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 1362.1
FF:10158-103A5 76 years, female 1362.1

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

867.6
Pig sample Sample description nTPM
Substantia nigra
nTPM: 841.2
Samples: 4

Max nTPM: 1016.1
Min nTPM: 698.4
Sample A Female 1016.1
Sample B Female 698.4
Sample C Male 899.2
Sample D Male 751.1
Midbrain
nTPM: 867.6
Samples: 4

Max nTPM: 1458.5
Min nTPM: 561.7
Sample A Female 1458.5
Sample B Female 631.7
Sample C Male 818.4
Sample D Male 561.7
Periaqueductal gray
nTPM: 800.1
Samples: 3

Max nTPM: 963.5
Min nTPM: 700.4
Sample B Female 736.4
Sample C Male 963.5
Sample D Male 700.4
Superior colliculi
nTPM: 800.4
Samples: 4

Max nTPM: 853.5
Min nTPM: 705.7
Sample A Female 853.5
Sample B Female 810.1
Sample C Male 832.1
Sample D Male 705.7

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

1056.8
Mouse sample Sample description nTPM
Midbrain
nTPM: 1056.9
Samples: 4

Max nTPM: 1074.4
Min nTPM: 1046.1
Sample A Male 1051.7
Sample B Male 1046.1
Sample C Female 1055.2
Sample D Female 1074.4

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

18.1
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 18.1
70919346 Antisense, RP_050713_01_B06, Mouse strain C57BL/6J (56 days, male) 22.0
846 Antisense, RP_Baylor_102983, Mouse strain C57BL/6J (56 days, male) 14.2
847 Antisense, RP_Baylor_102983, Mouse strain C57BL/6J (56 days, male) 12.7

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The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg Foundation.


contact@proteinatlas.org