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TISSUE MIDBRAIN Show tissue menu
ADIPOSE TISSUE ADRENAL GLAND AMYGDALA APPENDIX BASAL GANGLIA BONE MARROW BREAST CEREBELLUM CEREBRAL CORTEX CERVIX CHOROID PLEXUS COLON DUODENUM
ENDOMETRIUM EPIDIDYMIS ESOPHAGUS FALLOPIAN TUBE GALLBLADDER HEART MUSCLE HIPPOCAMPAL FORMATION HYPOTHALAMUS KIDNEY LIVER LUNG LYMPH NODE MIDBRAIN
OVARY PANCREAS PARATHYROID GLAND PITUITARY GLAND PLACENTA PROSTATE RECTUM RETINA SALIVARY GLAND SEMINAL VESICLE SKELETAL MUSCLE SKIN SMALL INTESTINE
SMOOTH MUSCLE SPINAL CORD SPLEEN STOMACH TESTIS THYMUS THYROID GLAND TONGUE TONSIL URINARY BLADDER VAGINA
Dictionary
Tissue proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:11752.8 nTPM
HPA Brain:27975.2 nTPM
GTEx:11752.8 nTPM
Pig:9315.4 nTPM
Mouse:4169.0 nTPM
Allen mouse:21.6 Expression energy

MIDBRAIN - Annotated protein expression
Pending normal tissue analysis

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

27975.2
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 19619.1
2586 Male, age 75, left hemisphere 31097.5
2219 Male, age 76, both hemispheres 30931.9
2666 Male, age 74, left hemisphere 25561.8
2828 Female, age 72, unknown 22396.9
1833 Male, age 53, unknown 18790.3
1870 Female, age 42, unknown 17263.8
1830 Male, age 51, unknown 17238.8
1827 Male, age 72, unknown 13321.8
2019 Male, age 18, unknown 11367.8
2411 Female, age 72, unknown 8220.1
Dorsal raphe nucleus
nTPM: 11375.2
1828 Male, age 53, unknown 16734.6
2047 Male, age 72, unknown 13619.0
2750 Male, age 76, both hemispheres 12385.8
2016 Female, age 72, unknown 9510.5
2298 Female, age 72, unknown 4626.0
Inferior colliculus
nTPM: 16290.6
2849 Male, age 72, unknown 29417.7
1890 Male, age 53, unknown 16124.9
1848 Female, age 42, unknown 13339.3
2097 Female, age 72, unknown 6280.6
Median raphe nucleus
nTPM: 27975.2
2220 Male, age 76, midline 27975.2
Periaquaductal grey, anterior
nTPM: 11359.6
2502 Female, age 75, unknown 14095.5
1795 Male, age 51, unknown 10265.6
1947 Male, age 18, unknown 9717.7
Periaquaductal grey, dorsal
nTPM: 17139.3
2850 Male, age 76, both hemispheres 30331.9
1831 Male, age 72, unknown 14801.8
2464 Female, age 72, unknown 12250.5
1840 Male, age 53, unknown 11173.0
Periaquaductal grey, lateral
nTPM: 10245.4
2140 Male, age 76, both hemispheres 14195.0
2053 Male, age 18, unknown 10539.7
2272 Male, age 74, both hemispheres 6001.4
Pretectal area
nTPM: 15982.7
1816 Male, age 51, unknown 23370.5
1944 Female, age 72, unknown 22760.7
1817 Female, age 42, unknown 21674.1
2667 Female, age 75, unknown 21601.6
1815 Male, age 53, unknown 20742.7
2007 Male, age 72, unknown 16585.8
2825 Male, age 18, unknown 16402.8
2407 Male, age 75, both hemispheres 12248.4
2224 Female, age 72, unknown 8173.6
2316 Male, age 76, right hemisphere 6843.4
2273 Male, age 74, both hemispheres 5405.6
Red nucleus
nTPM: 17522.2
2584 Male, age 75, left hemisphere 24732.8
2588 Male, age 74, left hemisphere 21965.5
2823 Male, age 76, right hemisphere 20530.5
2503 Female, age 72, unknown 20342.9
1954 Female, age 42, unknown 18848.3
1865 Male, age 51, unknown 17930.9
2785 Male, age 18, unknown 17203.0
2227 Male, age 72, unknown 15157.1
1904 Male, age 53, unknown 14835.9
2769 Male, age 72, unknown 14651.3
2725 Female, age 75, unknown 12650.2
1821 Female, age 72, unknown 11418.4
Substantia nigra
nTPM: 19179.3
2665 Male, age 74, both hemispheres 36352.8
2699 Male, age 18, unknown 33485.1
1916 Female, age 42, unknown 22327.3
1941 Male, age 53, unknown 18848.4
2583 Male, age 75, right hemisphere 16467.9
1889 Female, age 72, unknown 15367.1
2590 Female, age 75, unknown 12767.6
2241 Male, age 72, unknown 12748.4
1851 Male, age 51, unknown 12171.0
2409 Female, age 72, unknown 11257.7
Superior colliculus
nTPM: 15286.1
2664 Male, age 75, both hemispheres 27670.8
2087 Female, age 72, unknown 18215.7
2587 Male, age 74, left hemisphere 16135.8
1913 Female, age 42, unknown 15276.3
2668 Female, age 75, unknown 14489.4
1839 Male, age 51, unknown 13723.8
1895 Male, age 76, right hemisphere 12860.0
1995 Male, age 72, unknown 12343.8
2261 Male, age 18, unknown 11327.7
1796 Male, age 53, unknown 10817.3
Ventral tegmental area
nTPM: 15274.4
2218 Male, age 76, both hemispheres 24690.6
2223 Female, age 72, unknown 17611.9
1942 Male, age 51, unknown 15207.0
1915 Female, age 42, unknown 12857.3
2021 Male, age 53, unknown 10981.2
2410 Female, age 72, unknown 10298.2

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

11752.8
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 11752.8
Samples: 139

Max nTPM: 48774.2
Min nTPM: 1755.3
Std nTPM: 8803.5
Median nTPM: 9186.8
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 48774.2
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 40649.9
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 39744.7
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 38408.9
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 38264.3
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 31947.7
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 30477.7
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 28891.1
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 27463.2
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 27280.9
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 26115.6
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 24133.6
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 23503.3
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 23370.0
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 22917.2
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 22837.9
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 22795.4
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 22103.7
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 22014.5
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 21475.7
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 21446.3
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 21249.3
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 21045.9
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 18774.1
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 18489.9
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 17773.9
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 17587.8
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 17544.2
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 17335.2
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 17159.3
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 16870.0
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 16706.4
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 16588.5
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 15174.4
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 14694.9
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 14624.5
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 14419.6
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 14159.5
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 13553.9
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 13339.0
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 13206.5
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 12919.5
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 12816.2
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 12741.5
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 12629.2
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 12596.4
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 11878.7
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 11581.5
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 11181.3
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 11163.2
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 11028.8
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 10892.8
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 10829.2
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 10666.2
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 10663.2
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 10613.8
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 10612.3
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 10610.1
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 10526.6
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 10484.6
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 10271.2
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 10096.2
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 9608.0
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 9556.2
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 9436.3
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 9300.1
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 9264.4
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 9232.1
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 9219.1
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 9186.8
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 9081.1
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 8914.1
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 8747.4
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 8709.0
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 8689.4
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 8197.2
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 8098.6
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 7710.6
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 7512.4
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 7461.5
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 7215.7
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 7125.3
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 7124.4
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 7083.2
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 7077.2
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 7072.2
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 6985.7
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 6884.7
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 6804.0
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 6797.0
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 6739.1
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 6715.3
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 6684.9
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 6650.8
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 6491.3
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 6349.9
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 6234.9
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 6126.3
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 5744.6
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 5689.2
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 5548.0
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 5538.9
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 5513.1
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 5509.6
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 5458.5
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 5361.2
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 5343.6
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 5330.3
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 5213.3
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 5125.4
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 5103.8
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 5066.7
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 5033.2
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 4847.6
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 4803.9
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 4689.5
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 4614.1
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 4584.7
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 4560.5
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 4537.4
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 4474.9
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 4401.4
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 4248.6
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 4211.7
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 4181.5
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 4085.6
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 4070.2
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 4018.1
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 3873.9
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 3840.8
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 3795.9
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 3547.3
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 3461.1
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 3416.3
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 3163.3
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 2967.3
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 2679.8
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 2425.6
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 1755.3
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MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

9315.4
Pig sample Sample description nTPM
Substantia nigra
nTPM: 8195.3
Samples: 4

Max nTPM: 10255.5
Min nTPM: 5174.1
Sample A Female 10255.5
Sample B Female 7234.7
Sample C Male 10116.8
Sample D Male 5174.1
Midbrain
nTPM: 9315.4
Samples: 4

Max nTPM: 12699.0
Min nTPM: 6593.5
Sample A Female 8028.6
Sample B Female 12699.0
Sample C Male 9940.5
Sample D Male 6593.5
Periaqueductal gray
nTPM: 7011.3
Samples: 3

Max nTPM: 8021.0
Min nTPM: 5939.7
Sample B Female 7073.3
Sample C Male 8021.0
Sample D Male 5939.7
Superior colliculi
nTPM: 7411.9
Samples: 4

Max nTPM: 9470.6
Min nTPM: 2359.3
Sample A Female 8810.7
Sample B Female 2359.3
Sample C Male 9470.6
Sample D Male 9007.1

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

4169.0
Mouse sample Sample description nTPM
Midbrain
nTPM: 4169.1
Samples: 4

Max nTPM: 4304.2
Min nTPM: 3911.9
Sample A Male 4304.2
Sample B Male 4296.1
Sample C Female 4164.0
Sample D Female 3911.9

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

21.6
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 21.6
75080269 Antisense, RP_060412_06_H09, Mouse strain C57BL/6J (56 days, male) 22.5
73906215 Antisense, RP_051212_04_H07, Mouse strain C57BL/6J (56 days, male) 20.8

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The Human Protein Atlas project is funded
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